CONTROLLED RELEASE SOCIETY Volume 19 • Number 32 • 2002 NEWSLETTER CRS Updates Entrepeneuer Scientific Tomorrow’s Passing theGavel Passing Spotlight: ALZA www.controlledrelease.org We characterize macromolecules from eighteen different angles. So you don’t have to. Eighteen angles may sound like a lot. But it’s not when Wyatt instruments have helped thousands of scientists, you consider that molecular weights and sizes can’t be from Nobel laureates to members of the National Academy determined accurately from one or two angles. of Sciences to researchers in over 50 countries worldwide. That’s why Wyatt’s multi-angle light scattering systems We also provide unmatched training, service, and deploy the greatest number of detectors over the support, as well as ongoing access to our nine PhD broadest range of angles. In fact, a Wyatt DAWN® scientists with broad expertise in liquid chromatography, instrument directly measures molecular weights polymer chemistry, protein science, biochemistry, and sizes without column calibration or and light scattering. reference standards —with up to 25 times For more information on our more precision than one or full range of instruments, worldwide dealer two angle instruments.* network, applications, and a bibliography No wonder 28 of the of light scattering papers, please call top 30 chemical, pharmaceutical, 805-681-9009, fax us at 805-681-0123, or visit us at and biotechnology companies rely on www.wyatt.com. We’ll show Wyatt instruments, as do all major fed- you how to generate data eral regulatory agencies and national laboratories. so precise, you won’t believe CORPORATION your eyes. *Precision improvement from measuring with Wyatt Multi-Angle Light scattering detectors vs. One or Two-angle light scattering detectors under typical chromatography conditions. All trademarks and registered trademarks are properties of their respective holders. ©2002 Wyatt Technology. All rights reserved. Editors CONTROLLED RELEASE SOCIETY Bozena Michniak & Ijeoma Uchegbu Consumer & Diversified Products Special Feature Editor Jerome Barra NEWSLETTER Managing Editor Volume 19 • Number 3 • 2002 Jaymie Griffin Thanks to members of the Publications Newsletter Subcommittee for helping with this inthisissue issue: Martyn Davies, Agis From the Editor Kydonieus, Harlan Hall, and Mike ............................................................................................................................................... 1 Rathbone. An introduction to the editorial team. The Controlled Release Society Passing the Gavel ........................................................................................................................................... 2 Newsletter is the official newsletter of As we say good-bye and thank you to current, Past President Dr. Kinam Park we welcome current the Controlled Release Society. The President, Professor Alexander (Sandy) Florence. newsletter is published three times annually providing scientific and technical information pertinent to the Pharm News ..................................................................................................................................................... 4 controlled release community and news The Animal Heath Consortium – a new initiative offers a communication forum to member about society and chapter activities. organizations, and interactions between humans and animals bears well for next year’s conference. Members receive the newsletter via mail. The newsletter may also be Awarding Excellence .................................................................................................................................... 5 viewed on-line at The Controlled Release Society showcases the impressive list of winners awarded for their excellence at www.controlledrelease.org. the Annual Meeting in Seoul, Korea. Newsletter articles reflect only the views of the authors. Publication of Scientifically Speaking ................................................................................................................................. 7 articles or advertisements within the Formulation of gene delivery vectors offers an exciting opportunity for interdisciplinary research. Controlled Release Society Newsletter does not constitute endorsement by the Spotlight: Alza ................................................................................................................................................ 12 Controlled Release Society or its A leader in the development and manufacturing of drug delivery technology based pharmaceutical agents of products, services, or views products for the healthcare industry. expressed herein. No representation is made as to the accuracy hereof and Thanks to Donors ......................................................................................................................................... 13 the publication is printed subject to Thank you 2002 educational and social donors. errors and omissions. Editorial contributions should be Our Technology ............................................................................................................................................ 17 directed to Jaymie Griffin, Managing Part one of a two part article on the use of In Vitro dissolution testing procedures for veterinary drug Editor, products. ([email protected]) and are subject to the terms and conditions People on the Move .................................................................................................................................... 23 of the Editorial and Publication Release. Publisher assumes no responsibility for Kevin Shakesheff is honored at MIT’s award ceremony. the safety or return of artwork, photographs, or manuscripts. Tomorrow’s Scientific Entrepreneurs ................................................................................................... 23 A spin-out company from The University of Nottingham was named as the authors of the best business Requests for advertisement placement plan to commercialize British science. may be directed to the Business Development Department; telephone Consumer & Diversified Products .......................................................................................................... 24 +1 (763)512-0909, or e-mail at [email protected]. All Take a look at the importance of controlled release systems in the consumer and diversified products. advertisements are subject to “General Conditions of Sale.” Unauthorized reproduction in whole or in part is prohibited. Requests for permission should be directed to the On the cover – Managing Editor. Call For Nominations .............................1 ©Copyright 2002 Controlled Release Transition ...................................................6 Society. All rights reserved. Controlled Release Society Patent Watch ............................................9 13355 Tenth Avenue North, Suite 108 Minneapolis, MN 55441-5554 Member Release .................................. 16 +1(763)512-0909 telephone +1(763)765-2329 facsimile CRS Chapter News .............................. 16 [email protected] [email protected] In the News Contact [email protected] News briefs from around the globe ........ 22 regarding new or existing membership service or publication purchase issues. JCR Highlights ....................................... 26 Contact [email protected] regarding meeting registration. Event Calendar...................................... 27 Polyhedral drug delivery vesicles. Photo provided by Contact [email protected] Doctors, I. F. Uchegbu, A.G. Schatzlein, and A.T. for information about exhibiting, Florence, School of Pharmacy, University of London. advertising or other visibility opportunities. Dedicated to the science and technology of controlled release and delivery Contact [email protected] and promoting education by releasing science to deliver a better future. for meeting program information. From the Editor It was with sadness that I learned that my colleague David Doelker. After 4 years working on Friend had decided to resign from his position as Co-Editor the potentials of solubility By Bo Michniak of the Newsletter. Dave had been Editor for many years and parameter and surface energy in invited me to help him with this task about a year ago. I pharmaceutical formulation, Dr. Barra joined Firmenich SA, think you will all agree that he did a wonderful job during a world leading flavor and fragrance house, in Geneva his tenure. We wish him well in all his future ventures. (Switzerland) in 1999 as Pharmaceutical Technology Meanwhile, I would like to welcome our new Co-Editor on Manager where he created a dedicated pharmaceutical board, Ijeoma Uchegbu Ph.D. and Consumer & Diversified development laboratory for flavoring active ingredients. Products Special Feature Editor, Jerome Barra Ph.D. Some areas of investigation, in collaboration with internal research fellows, include flavor interactions with active Dr. Uchegbu is currently a ingredients or packaging, bitter masking, flavor perception, Senior Lecturer in drug and performance of flavor delivery systems in pharmaceutical delivery at the University of and non-pharmaceutical applications. Strathclyde in Glasgow, U.K. She graduated with a degree in We now have one U.S. based Editor and one in Europe pharmacy from the University which allows the newsletter to be even more global. We hope of Benin in Nigeria,