1 Q Systemic drugs and ocular toxicity: Matching Chlorpromazine (Thorazine)? Blue tinting of vision Retinopathy rare at Thioridazine (Mellaril) doses <800 mg/d Tamoxifen Blair Witch cataract Iritis, hypotony can Sildenafil (Viagra) develop Cidofovir Causes a crystalline retinopathy Isotretinoin (Accutane) Causes nyctalopia Rifabutin Yellow tinting of vision Digitalis Causes uveitis with hypopyon (Start with chlorpromazine and work down the list) 2 A Systemic drugs and retinalocular toxicity: Matching Chlorpromazine (Thorazine) Blue tinting of vision Retinopathy rare at Thioridazine (Mellaril) doses <800 mg/d Tamoxifen Blair Witch cataract Iritis, hypotony can Sildenafil (Viagra) develop Cidofovir Causes a crystalline retinopathy Isotretinoin (Accutane) Causes nyctalopia Rifabutin Yellow tinting of vision Digitalis Causes uveitis with hypopyon 3 Systemic drugs and ocular toxicity: Matching Chlorpromazine: Blair Witch cataract 4 Q Systemic drugs and retinalocular toxicity: Matching Chlorpromazine (Thorazine) Blue tinting of vision Retinopathy rare at ThioridazineWhat class of medicine (isMellaril chlorpromazine?) It is a phenothiazine doses <800 mg/d TamoxifenWhat sort of med are phenothiazines? Blair Witch cataract They are neuroleptics (but have other uses as well) Iritis, hypotony can Sildenafil (Viagra) In addition to cataracts, what ophthalmic effects does develop high-dose chlorpromazine therapy have? CidofovirIt causes pigmentation of the lids and conj Causes a crystalline retinopathy IsotretinoinWhat corneal finding (Accutane)is associated with high-dose phenothiazine use? Causes nyctalopia Corneal verticillata Rifabutin Yellow tinting of vision Digitalis Causes uveitis with hypopyon 5 A Systemic drugs and retinalocular toxicity: Matching Chlorpromazine (Thorazine) Blue tinting of vision Retinopathy rare at ThioridazineWhat class of medicine (isMellaril chlorpromazine?) It is a phenothiazine doses <800 mg/d TamoxifenWhat sort of med are phenothiazines? Blair Witch cataract They are neuroleptics (but have other uses as well) Iritis, hypotony can Sildenafil (Viagra) In addition to cataracts, what ophthalmic effects does develop high-dose chlorpromazine therapy have? CidofovirIt causes pigmentation of the lids and conj Causes a crystalline retinopathy IsotretinoinWhat corneal finding (Accutane)is associated with high-dose phenothiazine use? Causes nyctalopia Corneal verticillata Rifabutin Yellow tinting of vision Digitalis Causes uveitis with hypopyon 6 Q Systemic drugs and retinalocular toxicity: Matching Chlorpromazine (Thorazine) Blue tinting of vision Retinopathy rare at ThioridazineWhat class of medicine (isMellaril chlorpromazine?) It is a phenothiazine doses <800 mg/d TamoxifenWhat sort of med are phenothiazines? Blair Witch cataract They are neuroleptics (but have other uses as well) Iritis, hypotony can Sildenafil (Viagra) In addition to cataracts, what ophthalmic effects does develop high-dose chlorpromazine therapy have? CidofovirIt causes pigmentation of the lids and conj Causes a crystalline retinopathy IsotretinoinWhat corneal finding (Accutane)is associated with high-dose phenothiazine use? Causes nyctalopia Corneal verticillata Rifabutin Yellow tinting of vision Digitalis Causes uveitis with hypopyon 7 A Systemic drugs and retinalocular toxicity: Matching Chlorpromazine (Thorazine) Blue tinting of vision Retinopathy rare at ThioridazineWhat class of medicine (isMellaril chlorpromazine?) It is a phenothiazine doses <800 mg/d TamoxifenWhat sort of med are phenothiazines? Blair Witch cataract They are neuroleptics Iritis, hypotony can Sildenafil (Viagra) In addition to cataracts, what ophthalmic effects does develop high-dose chlorpromazine therapy have? CidofovirIt causes pigmentation of the lids and conj Causes a crystalline retinopathy IsotretinoinWhat corneal finding (Accutane)is associated with high-dose phenothiazine use? Causes nyctalopia Corneal verticillata Rifabutin Yellow tinting of vision Digitalis Causes uveitis with hypopyon 8 Q Systemic drugs and retinalocular toxicity: Matching Chlorpromazine (Thorazine) Blue tinting of vision Retinopathy rare at ThioridazineWhat class of medicine (isMellaril chlorpromazine?) It is a phenothiazine doses <800 mg/d TamoxifenWhat sort of med are phenothiazines? Blair Witch cataract They are neuroleptics Iritis, hypotony can Sildenafil (Viagra) WhatIn sortaddition of drug to cataracts,are neuroleptics? what ophthalmic effects does develop Theyhigh are- doseantipsychotics chlorpromazine--so-called therapy ‘major have? tranquilizers’ CidofovirIt causes pigmentation of the lids and conj Causes a crystalline retinopathy IsotretinoinWhat corneal finding (Accutane)is associated with high-dose phenothiazine use? Causes nyctalopia Corneal verticillata Rifabutin Yellow tinting of vision Digitalis Causes uveitis with hypopyon 9 A Systemic drugs and retinalocular toxicity: Matching Chlorpromazine (Thorazine) Blue tinting of vision Retinopathy rare at ThioridazineWhat class of medicine (isMellaril chlorpromazine?) It is a phenothiazine doses <800 mg/d TamoxifenWhat sort of med are phenothiazines? Blair Witch cataract They are neuroleptics Iritis, hypotony can Sildenafil (Viagra) WhatIn sortaddition of drug to cataracts,are neuroleptics? what ophthalmic effects does develop Theyhigh are- doseantipsychotics chlorpromazine--so-called therapy ‘major have? tranquilizers’ CidofovirIt causes pigmentation of the lids and conj Causes a crystalline retinopathy IsotretinoinWhat corneal finding (Accutane)is associated with high-dose phenothiazine use? Causes nyctalopia Corneal verticillata Rifabutin Yellow tinting of vision Digitalis Causes uveitis with hypopyon 10 Q Systemic drugs and retinalocular toxicity: Matching Chlorpromazine (Thorazine) Blue tinting of vision Retinopathy rare at ThioridazineWhat class of medicine (isMellaril chlorpromazine?) It is a phenothiazine doses <800 mg/d TamoxifenWhat sort of med are phenothiazines? Blair Witch cataract They are neuroleptics Iritis, hypotony can Sildenafil (Viagra) In addition to cataracts, what ophthalmic effects does develop high-dose chlorpromazine therapy have? CidofovirIt causes pigmentation of the lids and conj Causes a crystalline retinopathy IsotretinoinWhat corneal finding (Accutane)is associated with high-dose phenothiazine use? Causes nyctalopia Corneal verticillata Rifabutin Yellow tinting of vision Digitalis Causes uveitis with hypopyon 11 A Systemic drugs and retinalocular toxicity: Matching Chlorpromazine (Thorazine) Blue tinting of vision Retinopathy rare at ThioridazineWhat class of medicine (isMellaril chlorpromazine?) It is a phenothiazine doses <800 mg/d TamoxifenWhat sort of med are phenothiazines? Blair Witch cataract They are neuroleptics Iritis, hypotony can Sildenafil (Viagra) In addition to cataracts, what ophthalmic effects does develop high-dose chlorpromazine therapy have? CidofovirIt causes pigmentation of the lids and conj Causes a crystalline retinopathy IsotretinoinWhat corneal finding (Accutane)is associated with high-dose phenothiazine use? Causes nyctalopia Corneal verticillata Rifabutin Yellow tinting of vision Digitalis Causes uveitis with hypopyon 12 Systemic drugs and ocular toxicity: Matching Chloropromazine-associated pigmentation 13 Q Systemic drugs and retinalocular toxicity: Matching Chlorpromazine (Thorazine) Blue tinting of vision Retinopathy rare at ThioridazineWhat class of medicine (isMellaril chlorpromazine?) It is a phenothiazine doses <800 mg/d TamoxifenWhat sort of med are phenothiazines? Blair Witch cataract They are neuroleptics Iritis, hypotony can Sildenafil (Viagra) In addition to cataracts, what ophthalmic effects does develop high-dose chlorpromazine therapy have? CidofovirIt causes pigmentation of the lids and conj Causes a crystalline retinopathy IsotretinoinWhatDoes corneal it cause finding a pigmentary(Accutane)is associated retinopathy with high- doseas well? phenothiazineVery rarely use? Causes nyctalopia Corneal verticillata Rifabutin Yellow tinting of vision Digitalis Causes uveitis with hypopyon 14 A Systemic drugs and retinalocular toxicity: Matching Chlorpromazine (Thorazine) Blue tinting of vision Retinopathy rare at ThioridazineWhat class of medicine (isMellaril chlorpromazine?) It is a phenothiazine doses <800 mg/d TamoxifenWhat sort of med are phenothiazines? Blair Witch cataract They are neuroleptics Iritis, hypotony can Sildenafil (Viagra) In addition to cataracts, what ophthalmic effects does develop high-dose chlorpromazine therapy have? CidofovirIt causes pigmentation of the lids and conj Causes a crystalline retinopathy IsotretinoinWhatDoes corneal it cause finding a pigmentary(Accutane)is associated retinopathy with high- doseas well? phenothiazineVery rarely use? Causes nyctalopia Corneal verticillata Rifabutin Yellow tinting of vision Digitalis Causes uveitis with hypopyon 15 Q Systemic drugs and retinalocular toxicity: Matching Chlorpromazine (Thorazine) Blue tinting of vision Retinopathy rare at ThioridazineWhat class of medicine (isMellaril chlorpromazine?) It is a phenothiazine doses <800 mg/d TamoxifenWhat sort of med are phenothiazines? Blair Witch cataract They are neuroleptics Iritis, hypotony can Sildenafil (Viagra) In addition to cataracts, what ophthalmic effects does develop high-dose chlorpromazine therapy have? CidofovirIt causes pigmentation