(12) STANDARD PATENT (11) Application No. AU 2004318169 B2 (19) AUSTRALIAN PATENT OFFICE (54) Title Low sodium salt of botanic origin (51) International Patent Classification(s) A23L 1/237 (2006.01) C01D 3/04 (2006.01) (21) Application No: 2004318169 (22) Date of Filing: 2004.11.09 (87) WIPO No: W005/097681 (30) Priority Data (31) Number (32) Date (33) Country 10/819,001 2004.04.06 US (43) Publication Date: 2005.10.20 (44) Accepted Journal Date: 2010.12.09 (71) Applicant(s) Council of Scientific and Industrial Research (72) Inventor(s) Bhatt, Ajoy Muralidharbhai;Eswaran, Karuppanan;Patolia, Jinalal Shambhubhai;Reddy, Alamuru Venkata Rami;Shah, Rajul Ashvinbhai;Barot, Bhargav Kaushikbhai;Mehta, Aditya Shantibhai;Gandhi, Mahesh Ramniklal;Mody, Kalpana Haresh;Reddy, Muppala Parandhami;Ghosh, Pushpito Kumar (74) Agent / Attorney Cullens Patent and Trade Mark Attorneys, Level 32 239 George Street, Brisbane, QLD, 4000 (12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization 11111|11| 1 111 |1 11111111 1111| 1111111|111 1111111 ||111 International Bureau 1111111 111111 111111111111111 1111 ii1111li iili (43) International Publication Date (10) International Publication Number 20 October 2005 (20.10.2005) PCT WO 2005/097681 Al (51) International Patent Classification7 : C01D 3/04, Marine Chemicals Research Institute, Bhavnagar, Gujarat A23L 1/237 364 002 (IN). BHATT, Ajoy, Muralidharbhai [IN/IN]; Central Salt and Marine Chemicals Research Institute, (21) International Application Number: Bhavnagar, Gujarat 364 002 (IN). REDDY, Alamuru, PCT/IB2004/003678 Venkata, Rami [IN/IN]; Central Salt and Marine Chemi cals Research Institute, Bhavnagar, Gujarat 364 002 (IN). (22) International Filing Date:9(74) Agents: BHOLA, Ravi et al.; K & S Partners, 84-C, C6 November 2004 (09.11.2004) Lane, Off Central Avenue, Sainik Farms, New Delhi 110 062 (IN). (25) Filing Language: English (81) Designated States (unless otherwise indicated,for every (26) Publication Language: English kind of nationalprotection available): AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, ClIL CN, (30) Priority Data: CO, CR, CU, CZ, DE, DK, DM, DZ, EC, FE, EU, ES, H, 10/819,001 6 April 2004 (06.04.2004) US AT,GB, PL,GD, PT, GE, ROA GIL ,B, GM, S,HR, S,HU,BW, ID, S, IL, BZ, IN, CA, IS, TJ,JP, TM,KE, KG, KP, KR, KZ, LC, LK, LR, LS, LI, LU, LV, MA, MD, (71) Applicant (for all designated States except US): COUN- MG, MK, MN, MW, MX, MZ, NA, M, NO, NZ, OM, PG, CIL OF SCIENTIFIC AND INDUSTRIAL RE TN, TR, T, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, SEARCH [IN/IN]; Rafi Marg, New Delhi 110 062 (IN). 9 (72) Inventors; and (84) Designated States (unless otherwise indicated, for every (75) Inventors/Applicants (for US only): GHOSH, Pushpito, Kumar [IN/IN]; Central Salt and Marine Chemicals Re- GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, search Institute, Bhavnagar, Gujarat 364 002 (IN). MODY, Kalpana, Haresh [IN/IN]; Central Salt and Marine European (AT, BE, BG, CL CY, CZ, DE, DK, FE, ES, H, Chemicals Research Institute, Bhavnagar, Gujarat 364 002 F, GB, GR, HU, IF, IS, IT, LU, MC, NL, PL, PT, RO, SF, (IN). REDDY, Muppala, Parandhami [IN/IN]; Central SI, SK, IR), GAPI (BE BJ, C, CG, CI, CM, GA, GN, GQ, Salt and Marine Chemicals Research Institute, Bhavnagar, GW, ML, MR, NE, SN, TD, TG). Gujarat 364 002 (IN). PATOLIA, Jinalal, Shambhubhai [IN/IN]; Central Salt and Marine Chemicals Research Institute, Bhavnagar, Gujarat 364 002 (IN). ESWARAN, Dcarato ue ule 4.17: Karuppanan [IN/IN]; Central Salt and Marine Chemicals Research Institute, Bhavnagar, Gujarat 364 002 (IN). earlier application(Rule 4.17(iii))for all designations SHAH, Rajul, Ashvinbhai [IN/IN]; Central Salt and Marine Chemicals Research Institute, Bhavnagar, Gujarat Published: 364 002 (IN). BAROT, Bhargav, Kaushikbhai [IN/IN]; with internationalsearch report Central Salt and Marine Chemicals Research Institute, Bhavnagar, Gujarat 364 002 (IN). GANDHI, Mahesh, Ramniklal [IN/IN]; Central Salt and Marine Chemicals For two-letter codes and other abbreviations, refer to the "Guid Research Institute, Bhavnagar, Gujarat 364 002 (IN). dance Notes on Codes andAbbreviations"appearing at the begin MEHTA, Aditya, Shantibhai [IN/(N]; Central Salt and ning of each regular issue of the FCT Gazette. Title: LOW SODIUM SALT OF BOTANIC ORIGIN I(54) Abstract: The invention describes the cost effective process for-(57) the preparation of a mixture of salts having low sodium salt salt) contain and exclusively derived from vegetable sources whiche(health have desired sodium chloride: potassium chloride ratio and traces of micronutrients including iodine, said salt is white in color and free flowing in nature. WO 2005/097681 PCT/IB2004/003678 1 LOW SODIUM SALT OF BOTANIC ORIGIN FIELD OF INVENTION: The present invention relates to a mixture of homogeneous salts having low sodium salt content of botanic origin and a process thereof. More particularly, the invention relates 5 to preparation of low sodium salt by blending crude sodium chloride and potassium chloride salts of plant by-products and then processing under aqueous conditions to obtain low sodium salt of desired composition in cost-effective manner. Low sodium salt is a mixture of sodium chloride and potassium chloride and is useful for those persons who have been advised to eat less common salt because of medical problems 10 like hypertension. BACKGROUND OF THE INVENTION It is well known that in certain cardiac and renal conditions, particularly when associated with edema, hypertension, arteriosclerosis, pregnancy complications and epilepsy, the diet must be relatively salt free to avoid further damage and to ameliorate 15 these conditions to the degree that control of diet can do. It is further known that the deleterious action of common table salt is due to sodium content thereof, since it is the sodium in the form of sodium ions, which must be avoided. Further, the tendency of the sodium content in the diet to cause an accumulation of fluids with a corresponding increase in the weight of the body tissues has underscored the importance of reducing 20 the sodium intake in diets. It is also known that potassium salt, a mineral present in many fruits, vegetables and legumes, protects against high blood pressure. Presence of potassium in low sodium salt inhibits sodium-induced hypertension. Reference may be made to "The Heinz Handbook of Nutrition" by Benzamin T Burton, published for H J Heinz co., by 25 McGrew Hill Book Co. Second Edition , Page 132-133, wherein, it is mentioned that the dietary need for potassium roughly equals to that of sodium. Salt is an excellent transporter for the supply of any nutrient supplement including potassium and micronutrients such as magnesium, calcium, zinc, iron and copper since people are consuming salt daily to improve the taste of food, though in a very limited 30 quantity; an important example being fortification of salt with iodine and iron for the control of goiter and anemia respectively (M G Venkatesh Mannar, S Jaipal and C S Pandya, Proceedings of sixth international congress, Seoul, 1989) WO 2005/097681 PCT/IB2004/003678 2 Many attempts have been made to provide salty tasting compositions as a substitute for table salt, which would give similar seasoning effect, and which is comprised of substantially reduced quantities of sodium chloride. In the fields of chemical technology, the recovery of low sodium salt from bittern, a by 5 product of salt industry, has gained importance because of its requirement for the patients suffering from heart problem and blood pressure and also for its nutritive value. Most typically, the pure salts are mixed together to produce low sodium salt but the prior art has also revealed that it is possible to directly produce low sodium salt by a process that involves chemical treatment of bittern with CaCl2 to separate sulfate; 10 concentrating bittern to produce mixture of salt and carnallite and finally processing the mixture to produce low sodium salt. Reference may be made to Biale and Zolotov, (EP0809942, dated 03-12-1998 and US patent No 5,853,792; 29 / 12/1998), entitled "Low sodium edible salt mixture" and " Low sodium edible salt composition and process for its preparation ", respectively, 15 wherein composition of low sodium edible salt is described which comprises, based on dry weight of ingredients, 0-50% sodium chloride, 45-99.5% potassium chloride and at least 0.5% additives, which comprise at least one edible nucleotide monophosphate salt and at least one member other than said nucleotide monophosphate salt selected from the group consisting of low organic acid, low organic acid salt, phosphoric acid, 20 phosphate salt, a magnesium salt, sugar and burnt sugar. The additives have the effect of countering the bitter taste of potassium chloride. However, the drawback of this process is that the product is obtained by simple physical mixing of the ingredients and hence difficult to get a homogenous mixture. Reference may be made to the patent of Rood Robert P. and Tilkian Sarko M. 25 (WO8500958, 14-3-1985, US4473595 dated 25-9-1984)), entitled "Low sodium salt substitute" wherein a process for low sodium composition is described as a substitute for common table salt and as a magnesium dietary supplement comprised of about 40 50% of sodium chloride, 25 -35% of potassium chloride and 15-25% of magnesium salt including magnesium sulfate and magnesium chloride. Presence of magnesium 30 overcomes potassium-generated bitterness or aftertaste while providing desirable magnesium dietary supplementation. However, the drawback of this process is that the product is obtained by simple physical mixing of the ingredients and hencd difficult to obtain a true homogeneous solid mixture.