1. Drugs acting on the Gastrointestinal System 1.1 Antacids and other drugs for dyspepsia 1.1.1 Aluminium- and magnesium- containing Aluminium hydroxide antacids Co-magaldrox (Mucogel®) Magnesium trisilicate 1.1.2 Antacid preparations containing simeticone Asilone® (for use in accordance with the Palliative Care Pain and Symptom Control Guidelines) 1.1.3 Other drugs for dyspepsia and gastro- Algicon® (second-line alginate) oesophageal disease Gaviscon Advance® liquid (first-line alginate) Gaviscon Infant® (Neonatal Unit only) 1.2 Antispasmodics and other drugs altering gut motility Alverine (Gastroenterology only) Dicycloverine Domperidone Hyoscine-n-butyl bromide Mebeverine Metoclopramide Peppermint oil 1.3 Ulcer-healing drugs 1.3.1 H2-receptor antagonists Cimetidine Ranitidine 1.3.3 Chelates and complexes Sucralfate 1.3.5 Proton pump inhibitors - Omeprazole capsules (first line PPI - Losec MUPS are non-formulary) see Salford PPI Strategy and Guidelines Lansoprazole orodispersible tablet (FasTab®) (for patients unable to swallow tablets) Rabeprazole (Gastroenterologists and Gastroenterology Surgeons only) 1.4 Acute diarrhoea 1.4.1 Adsorbents & bulk-forming Kaolin mixture 1.4.2 Antimotility drugs Codeine phosphate Loperamide 1.5 Chronic bowel disorders Colifoam® (hydrocortisone) Infliximab (in accordance with NICE guidance) - Follow restricted high cost drug procedure when prescribing infliximab Mesalazine Predenema® Predfoam® Predsol® Sulfasalazine Clipper® (Beclometasone dipropionate) (consultant gastroenterologist only) Budesonide Rectal Foam (consultant gastroenterologist only) Adalimumab (for Crohn’s disease) 1.6 Laxatives 1.6.1 Bulk forming laxatives Ispaghula husk (Fybogel®) Methylcellulose Sterculia (Normacol®) 1.6.2 Stimulant laxatives Bisacodyl Co-danthramer Co-danthrusate Docusate sodium Glycerol suppositories Senna Sodium picosulfate Neostigimine 1.6.3 Faecal softeners Arachis oil enema 1.6.4 Osmotic laxatives Lactulose (Gastroenterology only) Movicol® (do not use first line) Phosphate enema Micralax micro-enema® 1.6.5 Bowel cleansing solutions Fleet Phospho-soda® Klean-prep® Picolax® 1.7 Preparations for haemorrhoids 1.7.1 Soothing haemorrhoidal preps Anusol® 1.7.2 Compound preps with corticosteroids Anusol-HC® Xyloproct® 1.7.3 Rectal sclerosants Phenol 1.7.4 Management of anal fissures Dltiazem 2% cream (unlicensed - should not be used first line) Glyceryl trinitrate 0.4% (Rectogesic®) (for use in the treatment of anal fissure) 1.8 Stoma Care - contact Stoma Care Specialist for advice Dansac® soft paste 1.9 Drugs affecting intestinal secretions 1.9.2 Bile acid sequestrants Colestyramine 1.9.4 Pancreatin Creon® Pancrease® .
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