
<p> Curriculum Vitae: Max Joseph</p><p>Full Name Maxim Bruckshaw Joseph Email [email protected]</p><p>Address RRA54 Resident Tutor, Telephone 07908 498 447 University of Warwick, Coventry, CV7 4AL. Date of Birth 04/01/1985 Education (2008 – current) University of Warwick Ph.D ‘Microfluidic devices for DNA and protein interaction studies’. (2007 – 2008) University of Warwick M.Sc. (Hons) MOAC; Mathematical Biology and Biophysical Chemistry (distinction) (2003 – 2007) University of York B.Sc. (Hons) Biochemistry (1st class) Employment Sept. 2008 - Resident Tutor (Rootes residence), University of Warwick Current Live-in postgraduate for facilitation of student welfare and discipline in University residences. July 2005 - Smith&Nephew Research Centre (S&N RC), York July 2006 Year-in-industry placement within RC of major multinational medical products manufacturer. Research Interests Microfluidic analytical techniques in biology and biochemistry; particularly high throughput methods. High order regulation of gene expression through promoter and regulatory module interactions. Design and implementation of information pipelines for rapid analysis of experimental data. Laboratory experience Year-in-Industry: Developed a body of evidence to support the efficacy of a proposed improvement to an existing product, including primary tissue cult/ure, protein arrays, biochemical assays and literature reviews. Final Year Project: Cloning and expression of Metal Transport Protein (MTP) chimeras. Work indicated contribution of previously disregarded subdomains of MTP proteins to metal ion selectivity. MOAC miniprojects: 3 x 2 month placements in (Systems Biology, Electrochemistry and Neurosciences). Ph.D.: Primary research findings: Created library of regulatory module mutants by two step LCR process using oligonucleotides optimised by a Matlab program written by myself; Cloned mutants into promoter- containing plasmid and assessed effect of mutants on expression of GFP by flow cytometry; Designed and made PDMS microfluidic chip (water-in-oil droplets) for high throughput generation of LCR substrate mixtures. Publications M. Joseph and G. Koentges, “Mutant library creation by parallel assembly of partially degenerate oligonucleotides using OptiCut,” In preparation. R.P. Arasaradnam, L. Wedlake, H.J.N. Andreyev, N. Ouaret, M. Joseph, C.U. Nwokolo, K.D. Bardhan, and J.A. Covington, “A novel measure for identifying patients at risk of gastrointestinal toxicity during pelvic radiotherapy?,” In review. R.P. Arasaradnam, N. Quraishi, I. Kyrou, C.U. Nwokolo, M. Joseph, S. Kumar, K.D. Bardhan, and C.J. A., “Insights into ‘fermentonomics’: evaluation of volatile organic compounds (VOCs) in human disease using an electronic ‘e- nose’,” Journal of Medical Engineering & Technology, vol. 35, 2011, pp. 87-91. References James Covington (PhD supervisor, primary) [email protected] School of Engineering, University of Warwick, Coventry, CV4 7AL Georgy Koentges (PhD supervisor, secondary) [email protected] Biological Sciences, University of Warwick, Coventry, CV4 7AL Alison Rodgers (Course director) [email protected] MOAC DTC, University of Warwick, Coventry, CV4 7AL</p>
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