RESPIRATORY/CNS PHARMACOLOGY DRUG LIST 2010 Mark Tuttle

RESPIRATORY/CNS PHARMACOLOGY DRUG LIST 2010 Mark Tuttle

<p> RESPIRATORY/CNS PHARMACOLOGY DRUG LIST © 2010 Mark Tuttle - Non-selective CNS depressants oTrue Benzodiazepines oBarbiturates . Diazepam (Valium) . Thiopental . Flumazenil . Pentobarbital . Methly-β-carboline . Secobarbital . Anxiolytics . Barbital  Lorazepam . Phenobarbital  Alprazolam oOthers . Hypnotics . Propofol  Flurazepam . Etomidate  Triazolam . Ketamine  Temazepam . Non-barbiturate sedative hypnotics  Zolpidem  Zelepon - Local Anesthetics . Anticonvulsant oEsters  Diazepam . Cocaine  Lorazepam . Procaine  Clonazepam . Benzocaine . Muscle Relaxant . Tetracaine  Diazepam oAmides  Midazolam . Lidocaine oNon-benzodiazepine hypnotics . Bupivacaine . Zolpidem (Ambien) . Prilocaine . Ramelton . Ropivacaine oNon-benzodiazepine anxiolytics . Mepivicaine . Buspirone oToxins . Saxitoxin (puffer fish) - Parkinson’s Drugs . Tetrodotoxin oDopamine oLevadopa - General Anesthetics oCarbidopa oInhalational oSegeline . Halothane oBromocriptine . Isoflurane oParamipexole . Enflurane Amantadine . Sevoflurane o . Desflurane oBenztropine o(Trihexyphenidyl) . N2O . (Methoxyflurane) o(Procyclidine) . (Ether, Chloroform) o(Biperiden) oIntravenous . Barbiturates - CNS Stimulants . Propofol oMethylxanthines . Etomidate . Caffeine . Not non-selective CNS depressants . Theobromine  Opioids . Theophylline  Benzodiazepine oSympathetomimmetics .  Ketamine Amphetamines  Dextroamphetamine  Methylphneidate  (Phentermine & sibutramine)  Cocaine</p><p>- Benzodiazepines RESPIRATORY/CNS PHARMACOLOGY DRUG LIST © 2010 Mark Tuttle - Anti-psychotics - Antidepressants/Anti-Manics st oTypical (First-generation): D2 Block oTricyclic (1 Generation) . Phenothiazines . Imipramine  Aliphatic: Chloropromazine . Amitriptyline  Piperidine: Thioridazine . Nortriptyline  Piperazine: Fluphenazine . Desipramine . Thioxanthines . Clomipramine nd  Thiothixine oAtypical (2 Generation) . Butyrophenones . Bupropion  Haloperidol . Amoxapine</p><p> oAtypical (Second-generation): 5HT2 >D2 block oSerotonin-selective Reuptake Inhibitors (SSRIs) . Indoles . Fluoxetine  Clozapine . Sertaline  Risperidol . Peroxetine  Olanzepine . Excitalopram  Quetiapine oMood Stabilizors  Ziprazidone . Lithium .  Zotepine Valproic acid  Aripiprazole - Anti-epileptics  Amisulpride o Na + channel antiepileptics . Phenytoin - Opioids . Fosphenytoin oMorphine . Carbamazepine oEtrophine . Oxcarbazepine oHeroin . Valproic Acid oCodeine . Lamotrigine oDextromethorphan . Topiramate Meperidine o . Zonisamide Fentanyl o oEnhance GABA oMethadone . Benzodiazepines oPropoxyphene  Clonazepam Endogenous opiopeptins o  Diazepam/Lorazepam . Met-enkephalin . Barbiturates . β-endorphin  Phenobarbital oLow PC, don’t cross BBB 2+ oT-type Ca channel . Diphenoxylate . Ethosuximide . Loperamide oInhibit excitatory NT release oOpioid Antagonists . Gabapentin (α2δ) . Naloxone . Pregabalin (α2δ) . Naltrexone . Levatiracetam (SV2A) . (Nalmefene) oPartial-mixed agonists/antagonists . (Nalorphine) . Pentazocine . Nalbuphine . Botorphanol . Buprenorphine RESPIRATORY/CNS PHARMACOLOGY DRUG LIST © 2010 Mark Tuttle - Drugs of abuse oOpioids oSedative-hypnotics oEthanol oBenzodiazepines oVolatile intoxicants oAmphetamine type stimulants oCocaine oCaffeine oHallucinogens, phencyclidine, marijuana oNicotine</p><p>- Respiratory oβ-agonists . Epinephrine . Terbutaline . Albuterol . Salmeterol oAnticholinergics . Ipratropium bromide oGlucocorticoids . Prednisone . Prednisolone . Methylprednisolone . Triamcinolone . Triamcinolone acetonide . Beclomethasone . Fluticasone oLeukotriene Receptor Antagonists . Zafirlukast . Montelukast o 5-LO inhibitor s . Zileuton oMethylxanthines . Theophylline oMast Cell Stabilizers . Cromolyn sodium oProstaglandins . Epoprostenol oEndothelin antagonists . Bosentan oOpioid Agonists . Codeine . Dextromethorphan oExpectorants . Guaifenesin</p>

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