<p> Table of graduate student supervisor</p><p>Name Ji Min</p><p>Professional titles Professor</p><p>Doctoral supervisor Doctoral supervisor OR Master's supervisor Major Nano medicine, Medicinal Chemistry </p><p>Academic expertise 1. Design, synthesis and application of novel and research direction pharmaceutical nano-material 2. Anti-tumor activity of multi-targets kinase inhibitors 3. Design and synthesis of central nerves system (CNS) drugs 4. Research of Drug delivery system Current research and July, 2011 – July, 2014 other projects “ Technology development and industrialization of enzyme catalyzed synthesis of high quality atorvastatin calcium and its intermediates”, Major Achievements Transfer Projects of Jiangsu province (BA2011130), the team leader.</p><p> July, 2011 – July, 2014 “ Continuous chromatographic separation technique for preparation of high purity Netilmicin”, Major Achievements Transfer Projects of Jiangsu province (BA2011035), the team leader.</p><p> July, 2012 – July, 2014 “Green technology and industrialization of atorvastatin calcium preparation”, The prospective project of Jiangsu Province (BY2012203), the team leader.</p><p> July, 2009 – July, 2012 “ Multiple targets kinase inhibitors Segitinib for antitumor preclinical studies”, Social Development--- Technology Supporting Program of Jiangsu province (BE2009639), the team leader. Books and papers Books: 1.《Combinatory Chemistry》Chemical series of books in the 21st century Chemical Industry press 2004.6. Jimin Write 2.《Medicinal Chemistry》(Ordinary higher education " 15 " teaching materials of national-level planning " ) Higher Education Press 2004.11. Jimin join writing 3 . 《 Medicinal Chemistry 》 The guide for entrance of National operation pharmacist's qualifying examination Chinese Pharmaceutical Scientific and technological publishing house 1997,2001 Jimin join writing Papers:</p><p>1. Zhang, S. G.; Feng, C. L.; Cai, J.; Chen, J. Q.; Hu, H. Y.; Ji, M. Solvent free synthesis of 2-acylpyrroles and its derivatives catalysed by reuseable zinc oxide. Journal of Chemical Research 2013, 480- 482. 2. Zheng, Y. G.; Zheng, M.; Ling, X.; Liu, Y.; Xue, Y. S.; An, L.; Gu, N.; Ji, M. Design, synthesis, quantum chemical studies and biological activity evaluation of pyrazole-benzimidazole derivatives as potent Aurora A/B kinase inhibitors (vol 23, pg 3523, 2013). Bioorganic & Medicinal Chemistry Letters 2013, 23, 4471-4471. 3. Feng, C. L.; Zhang, S. G.; Chen, J. Q.; Cai, J.; Ji, M. First total synthesis of isoquinolinone alkaloid marinamide and its methyl ester. Chinese Chemical Letters 2013, 24, 767-769. 4. Zhang, S. G.; Huang, S.; Feng, C. L.; Cai, J.; Chen, J. Q.; Ji, M. Novel preparation of tiaprofenic acid. Journal of Chemical Research 2013, 406-408. 5. Zheng, M.; Zheng, Y. G.; Xie, L.; Chang, W. W.; Gu, N.; Ji, M. Orally Active Aurora A/B Kinase Inhibitor, AM-005, Suppresses the Growth of Human Colon Carcinoma Cells. Drug Development Research 2013, 74, 272-281. 6. Zheng, Y. G.; Zheng, M.; Liu, Y.; Xue, Y. S.; Zhang, L.; An, L.; Liu, L.; Ji, M. Design, Synthesis, and In vitro Antitumor Evaluation of Novel Phenylaminopyrimidine Derivatives. Medicinal Chemistry 2013, 9, 340-350. 7. Cai, J.; Sun, M.; Wu, X. Q.; Chen, J. Q.; Wang, P.; Zong, X.; Ji, M. Design and synthesis of novel 4-benzothiazole amino quinazolines Dasatinib derivatives as potential anti-tumor agents. European Journal Of Medicinal Chemistry 2013, 63, 702-712. 8. Zhang, S. G.; Feng, C. L.; Cai, J.; Chen, J. Q.; Ji, M. Total synthesis of a novel isoquinolinone alkaloid marinamide and its methyl ester. Journal of Chemical Research 2013, 291-293. 9. Zheng, M.; Zheng, Y. G.; Xue, Y. S.; Liu, Y.; An, L.; Zhang, L.; Ji, M.; Xue, B.; Wu, X.; Gong, X. D.; Gu, N.; Zhan, X. Synthesis and Quantum Chemical Studies of New 4-aminoquinazoline Derivatives as Aurora A/B Kinase Inhibitors. Chemical Biology & Drug Design 2013, 81, 399-407. 10. Wang, P.; Cai, J.; Yang, J. B.; Sun, C. L.; Li, L. S.; Ji, M. Solvent-Dependent Regioselective Oxidation of trans-Chalcones using Aqueous Hydrogen Peroxide. Journal Of The Brazilian Chemical Society 2013, 24, 518-522. 11. Wang, P.; Cai, J.; Yang, J. B.; Sun, C. L.; Li, L. S.; Hu, H. Y.; Ji, M. Zinc(II)-catalyzed oxidation of alcohols to carbonyl compounds with chloramine-T. Tetrahedron Letters 2013, 54, 533-535. 12. Duan, Y. B.; Ji, M.; Lu, X. H. Simultaneous high-performance liquid chromatographic determination of a rhein-diclofenac prodrug and its active compounds. Pharmazie 2013, 68, 12-14. 13. Wang, P.; Yang, J. B.; Cai, J.; Sun, C. L.; Li, L. S.; Ji, M. An efficient and facile synthesis of flavanones catalyzed by N- methylimidazole. Journal Of The Serbian Chemical Society 2013, 78, 917-920. 14. Cao, M.; Zhan, T. L.; Ji, M.; Zhan, X. Dimerization is necessary for MIM-mediated membrane deformation and endocytosis. Biochemical Journal 2012, 446, 469-475. 15. Cai, J.; Duan, Y. B.; Yu, J.; Chen, J. Q.; Chao, M.; Ji, M. Bone- targeting glycol and NSAIDS ester prodrugs of rhein: Synthesis, hydroxyapatite affinity, stability, anti-inflammatory, ulcerogenicity index and pharmacokinetics studies. European Journal Of Medicinal Chemistry 2012, 55, 409-419. 16. Hu, H. Y.; Liu, Y.; Zhong, H.; Zhu, Y. L.; Wang, C.; Ji, M. Heck- Type Cross-Dehydrogenative Coupling Reactions of Indolizines at the 3-Position with Electron-Deficient Alkenes through Palladium- Catalyzed C?H Activation. Chemistry-an Asian Journal 2012, 7, 884- 888. 17. Cai, J.; Zhang, S. N.; Zheng, M.; Wu, X. Q.; Chen, J. Q.; Ji, M. Design, synthesis, and in vitro antiproliferative activity of novel Dasatinib derivatives. Bioorganic & Medicinal Chemistry Letters 2012, 22, 806-810. 18. Wu, X. Q.; Li, M. D.; Tang, W. H.; Zheng, Y. G.; Lian, J. Q.; Xu, L.; Ji, M. Design, Synthesis, and In vitro Antitumor Activity Evaluation of Novel 4-pyrrylamino Quinazoline Derivatives. Chemical Biology & Drug Design 2011, 78, 932-940. 19. Zheng, Y. G.; Sun, M.; Liu, Y.; Li, M. D.; Ji, M. Design, Synthesis of Novel Quinazolone Alkaloids Derivatives as Potential Antitumor Agents. Medicinal Chemistry 2011, 7, 295-300. 20. Chen, J. Q.; Sun, M.; Cai, J.; Cao, M.; Zhou, W.; Ji, M. The Synthesis and Crystal Structure of (4 alpha,8 beta,13 beta,16 beta)- 13-Methyl-16,18-diol-17-Norkaurane: A Simultaneous Reduction Product of Isosteviol. Journal Of Chemical Crystallography 2011, 41, 519-522. 21. Chen, J. Q.; Zha, X. M.; Sun, M.; Cai, J.; Zhou, W.; Ji, M. Synthesis and In Vivo Acute Antihyperglycemic Evaluation of Novel Isosteviol Derivatives. Letters in Drug Design & Discovery 2010, 7, 686-693. 22. Zheng, Y. G.; Wu, X. Q.; Xue, B.; Li, M. D.; Ji, M. Design, Synthesis, Docking and Antitumor Activity of Quinazolino [3, 4-a] thieno [3, 2-d] pyrimidin-8-one Derivatives. Chemical Biology & Drug Design 2010, 76, 285-290. 23. Wu, X. Q.; Li, M. D.; Qu, Y.; Tang, W. H.; Zheng, Y. G.; Lian, J. Q.; Ji, M.; Xu, L. Design and synthesis of novel Gefitinib analogues with improved anti-tumor activity. Bioorganic & Medicinal Chemistry 2010, 18, 3812-3822. 24. Sun, M.; Wu, X. Q.; Chen, J. Q.; Cai, J.; Cao, M.; Ji, M. Design, synthesis, and in vitro antitumor evaluation of novel diaryl ureas derivatives. European Journal Of Medicinal Chemistry 2010, 45, 2299-2306. 25. Sun, M.; Chen, J. Q.; Cai, J.; Cao, M.; Yin, S. Q.; Ji, M. Simultaneously Optimized Support Vector Regression Combined With Genetic Algorithm for QSAR Analysis of KDR/VEGFR-2 Inhibitors. Chemical Biology & Drug Design 2010, 75, 494-505. 26. Duan, Y. B.; Yu, J.; Liu, S.; Ji, M. Synthesis of Anthraquinone- Ibuprofen Prodrugs with Hydroxyapatite Affinity and Anti- Inflammatory Activity Characteristics. Medicinal Chemistry 2009, 5, 577-582. 27. Sun, M.; Zheng, Y. G.; Wei, H. T.; Chen, J. Q.; Ji, M. QSAR studies on 4-anilino-3-quinolinecarbonitriles as Src kinase inhibitors using robust PCA and both linear and nonlinear models. Journal Of Enzyme Inhibition And Medicinal Chemistry 2009, 24, 1109-1116. 28. Zheng, Y. G.; Wu, X. Q.; Sun, M.; Feng, L. H.; Li, M. D.; Ji, M. Design, Synthesis, Crystal Structure and Antitumor Activity of A New Ethyl 3-(quinazolin-4-ylamino)-1H-pyrrole-2-carboxylate Derivative. Letters in Drug Design & Discovery 2009, 6, 538-541. 29. Duan, Y. B.; Yu, J.; Liu, H. F.; Ji, M. Bone-Targeting Anthraquinone-Diclofenac Prodrugs with Hydrolytic and Bone Affinity Characteristics. Letters in Drug Design & Discovery 2009, 6, 393-396. 30. Sun, M.; Chen, J. Q.; Wei, H. T.; Yin, S. Q.; Yang, Y.; Ji, M. Quantitative Structure-Activity Relationship and Classification Analysis of Diaryl Ureas Against Vascular Endothelial Growth Factor Receptor-2 Kinase Using Linear and Non-Linear Models. Chemical Biology & Drug Design 2009, 73, 644-654. 31. Wei, H. T.; Sun, M.; Ji, M. A straightforward expeditious synthesis of 5-nitrobenzo[b]thiophene-2-carbaldehyde. Journal Of Chemical Research-s 2009, 359-360. 32. Zheng, Y. G.; Li, M. D.; Zhang, S. N.; Ji, M. Novel preparation of gefitinib. Journal Of Chemical Research-s 2009, 388-390. 33. Sun, M.; Zheng, Y. G.; Wei, H. T.; Chen, J. Q.; Cai, J.; Ji, M. Enhanced Replacement Method-based Quantitative Structure - Activity Relationship Modeling and Support Vector Machine Classification of 4-Anilino-3-quinolinecarbonitriles as Src Kinase Inhibitors. Qsar & Combinatorial Science 2009, 28, 312-324. 34. Cai, J.; Zhou, W.; Chen, J. Q.; Sun, M.; Ji, M. Synthesis and Crystal Structure of Benzoyloxymethyl (4 alpha,8 beta,13 beta)-13- methyl-16-oxo-17-norkauran-18-carbonate Ester. Journal Of Chemical Crystallography 2009, 39, 108-111. 35. Liu, H. F.; Wu, X. Q.; Duan, Y. B.; Dou, R. B.; Sun, H. F.; Ji, M. An efficient one-pot synthesis of cyclovirobuxine A from buxozine C. Chemistry Of Natural Compounds 2008, 44, 829-830. 36. Shi, C. L.; Chen, H.; Li, Y.; Shi, D. Q.; Ji, M. A three- component synthesis of N-substituted quinoline-3-carbonitrile derivatives catalysed by L-proline. Journal Of Chemical Research-s 2008, 534-537. 37. Shi, C. L.; Shi, D. Q.; Kim, S. H.; Huang, Z. B.; Ji, S. J.; Ji, M. A novel and efficient one-pot synthesis of furo[3 ',4 ': 5,6]pyrido[2,3- c]pyrazole derivatives using organocatalysts. Tetrahedron 2008, 64, 2425-2432. 38. Liu, H. F.; Wu, X. Q.; Duan, Y. B.; Gu, B.; Ji, M. An efficient one-pot, two-step synthesis of cyclobuxophyllinine M from cyclovirobuxine D in aqueous media. Letters In Organic Chemistry 2008, 5, 140-141. 39. Yang, F.; Gu, A. Y.; Chen, Z. P.; Gu, N.; Ji, M. Multiple emulsion microbubbles for ultrasound imaging. Materials Letters 2008, 62, 121-124. 40. Sun, M.; Wei, H. T.; Li, D.; Zheng, Y. G.; Cai, J.; Ji, M. Mild and efficient one-pot synthesis of 2-imidazolines from nitriles using sodium hydrosulfide as catalyst. Synthetic Communications 2008, 38, 3151-3158. 41. Shi, C. L.; Shi, D. Q.; Kim, S. H.; Huang, Z. B.; Ji, M. A novel and efficient synthesis of 3,3 '-benzylidenebis(4-hydroxy-6- methylpyridin-2(1H)-one) derivatives through a multi-component reaction catalyzed by L-proline. Australian Journal Of Chemistry 2008, 61, 547-551. 42. Wei, H.; Cai, J.; Sun, M.; Ji, M. Synthesis of substituted thieno[2,3-b]pyrroles. Heteroatom Chemistry 2007, 18, 236-238. 43. Liu, H. F.; Ji, M.; Cai, J. Short and efficient approach towards buxozine-C, an alkaloid from Buxus sempervirens. Archiv Der Pharmazie 2006, 339, 675-676.</p><p>Email [email protected]</p><p>Other explanation</p><p>友情提醒:表格中所有内容均需用英文填写。如果贵实验室有其他情况想 加入介绍中,可以填写在 Other explanation 一栏。 另外,附件名务必请以“实验室+导师名”命名后于 10 月 18 日之前发送至 本人邮箱,[email protected]。</p><p>十分感谢各位老师您的支持工作!</p><p>顺祝老师您工作顺利,生活愉快,万事如意!</p>
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