<p> BIOL 4753, Human Molecular Genetics, Spring 2012 Class: 215 Williams Hall, 3:10PM-6:00PM (Tuesdays) Textbook: Strachan & Read, Human Molecular Genetics, 4th ed. (2010) Course Director: Prof. Mark Batzer, 643 LSA, x8-7102, [email protected], http://batzerlab.lsu.edu Teaching Assistant: Adam McLain, 653 LSA, x8-7104, [email protected]</p><p>DATE: LECTURE TOPICS:</p><p>January 17, 2012 Lecture 1: DNA Structure and chromosomes</p><p>January 24, 2012 Lecture 2: Genes in pedigrees, cloning</p><p>January 31, 2012 Lecture 3: Cloning cont., hybridization assays</p><p>February 7, 2012 Lecture 4: PCR, sequencing</p><p>February 14, 2012 Lecture 5: Human genome organization</p><p>February 21, 2012 Mardi Gras Holiday (No class)</p><p>February 28, 2012 Lecture 6: Human gene expression (A)</p><p>March 6, 2012 Lecture 7: Instability of the human genome, exam review</p><p>March 13, 2012 Exam 1 (40%)</p><p>March 20, 2012 Lecture 8: Physical and genetic mapping, complex diseases</p><p>March 27, 2012 Lecture 9: Genome projects, evolution</p><p>April 3, 2012 Lecture 10: Mobile elements</p><p>April 10, 2012 Spring Break (No class)</p><p>April 17, 2012 Lecture 11: Identifying human genes, forensics (A)</p><p>April 24, 2012 Lecture 12: Research literature discussion (A)</p><p>May 1, 2012 Lecture 13: Research literature discussion, exam review</p><p>May 7, 2012 Exam 2 (40%) Monday 3:00 – 5:00PM</p><p>Exams: Exams 1 and 2 will each count for 40% of the final grade (80% total). The second exam (Final) will be cumulative. The remaining 20% of the grade will come from the preparation and discussion of original research literature article outlines. The research outlines are due at the beginning of class on March 27th, 2012. The final/revised versions of the research outlines are due on April 17th. Graduate credit will be earned through the completion of additional essay examination questions. A single comprehensive make-up exam will be given May 7th to those students with excused absences from the exam during the semester.</p><p>Grading: A, 100-90%; B, 89-80%; C, 79-70%; D, 69-60%; F 59% and lower.</p>