<p> Supporting Table S4: </p><p>Term Count % P-Value Genes Pop Pop Fold Hits Total Enrichment rno04512:ECM- 20 1.9 3.56E-08 COL4A1,COL3A1,ITGA1,ITGA3 81 5590 4.540286 receptor interaction ,ITGA4,SDC4,COL5A3,COL5A2 ,COL5A1,HMMR,CD47,ITGA6,I TGB6,COL6A3,COL6A2,COL6A 1,LAMC2,TNN,THBS2,SPP1 rno04510:Focal 29 2.7 1.58E-06 CAV2,CAV1,PDGFB,COL3A1,P 195 5590 2.734649 adhesion XN,MYL9,VCL,ITGB6,COL6A3, SOS2,COL6A2,COL6A1,TNN,S HC2,THBS2,SPP1,COL4A1,PIK 3CB,ITGA1,MYLPF,PRKCG,IT GA3,ITGA4,VAV2,COL5A3,CO L5A2,COL5A1,ITGA6,LAMC2 rno05410:Hypertrophic 15 1.4 1.41E-04 CACNA2D1,TGFB3,ITGA1,CAC 84 5590 3.2836 cardiomyopathy (HCM) NB1,CACNB2,ITGA3,ITGA4,CA CNG1,CACNA2D2,TNNT2,ITG A6,SGCG,ITGB6,PRKAA2,SGC B rno05414:Dilated 15 1.4 3.00E-04 CACNA2D1,TGFB3,ITGA1,CAC 90 5590 3.064693 cardiomyopathy NB1,CACNB2,ITGA3,ITGA4,CA CNG1,CACNA2D2,TNNT2,ITG A6,SGCG,PLN,ITGB6,SGCB rno05412:Arrhythmoge 13 1.2 5.47E-04 CACNA2D1,ITGA1,CACNB1,C 74 5590 3.230352 nic right ventricular ACNB2,ITGA3,ITGA4,CACNG1, cardiomyopathy CACNA2D2,ITGA6,SGCG,PKP (ARVC) 2,ITGB6,SGCB rno04810:Regulation 24 2.2 8.41E-04 FGFR3,PDGFB,PIK3CB,LIMK1, 209 5590 2.111559 of actin cytoskeleton BAIAP2,FGF11,ITGA1,MYLPF,I TGA3,FGF13,ITGA4,VAV2,IQG AP1,PXN,MYL9,VCL,CHRM3,IT GA6,TIAM1,CHRM1,ITGB6,SO S2,MYH14,CD14 rno05200:Pathways in 31 2.9 0.00177 FGFR3,PDGFB,STAT5A,FGF1 317 5590 1.798211 cancer 1,TGFB3,FGF13,WNT4,CASP3, CDKN2B,SOS2,TGFA,FAS,WN T6,MYC,BMP4,BMP2,HSP90A A1,COL4A1,RALBP1,PIK3CB,R XRA,TGFBR2,FZD1,BRCA2,PR KCG,ITGA3,FZD2,RASSF5,ITG A6,LAMC2,TRA1 rno04610:Complement 11 1.0 0.004122 A2M,FGG,CD55,MASP1,F3,CD 70 5590 2.889568 and coagulation 59,SERPINE1,CFH,C1R,C1S,C cascades FD rno04010:MAPK 26 2.4 0.004628 FGFR3,PDGFB,TGFB3,FGF11, 266 5590 1.797339 signaling pathway CACNB1,CACNB2,FGF13,TNF RSF1A,CASP3,RASGRP3,MAP 3K1,SOS2,NFATC4,FAS,MYC, CCDC88B,CACNA2D1,TGFBR 2,PRKCG,CACNG1,CACNA2D 2,DUSP5,DUSP1,CACNA1G,G ADD45A,CD14 rno04360:Axon 15 1.4 0.008422 PLXNA2,LIMK1,EFNB2,EPHB3, 127 5590 2.17183 guidance EPHA2,SLIT3,EPHA4,SEMA6A, EPHA7,SEMA6C,UNC5B,SEM A3E,SRGAP3,NFATC4,UNC5C rno04670:Leukocyte 13 1.2 0.021172 PIK3CB,MYLPF,PRKCG,ITGA4 115 5590 2.078661 transendothelial ,VAV2,PXN,VCL,CLDN15,MYL9 migration ,VCAM1,RASSF5,PTK2B,RAP GEF3 rno03320:PPAR 9 0.8 0.037036 CPT1C,LPL,SLC27A1,ACADM, 71 5590 2.330893 signaling pathway RXRA,SCD,ACSL3,CPT1A,AC OX3 rno04530:Tight 13 1.2 0.048366 PARD6B,PARD3,VAPA,MYH2, 130 5590 1.838816 junction MYLPF,PRKCG,TJAP1,CLDN1 5,MYL9,EPB4.1L1,MYH14,PPP 2R2B,MYH7B rno04640:Hematopoiet 9 0.8 0.059172 CD55,ITGA6,CD3E,CD59,IL4R 78 5590 2.121711 ic cell lineage A,ITGA1,ITGA3,ITGA4,CD14 rno05223:Non-small 7 0.6 0.060477 RASSF5,PIK3CB,RXRA,SOS2, 52 5590 2.475329 cell lung cancer TGFA,PRKCG,FOXO3 rno04115:p53 8 0.7 0.064783 STEAP3,CASP3,CCNB2,SERPI 66 5590 2.228868 signaling pathway NE1,FAS,PMAIP1,CCNG2,GAD D45A rno04920:Adipocytokin 8 0.7 0.069155 CPT1C,TNFRSF1A,SOCS3,RX 67 5590 2.195601 e signaling pathway RA,PRKAA2,ACSL3,IRS1,CPT1 A rno00071:Fatty acid 6 0.5 0.074727 CPT1C,ACADM,ACSL3,DCI,CP 42 5590 2.62688 metabolism T1A,ACOX3 rno04650:Natural killer 10 0.9 0.091204 CASP3,PTK2B,PIK3CB,SOS2,L 100 5590 1.838816 cell mediated OC498276,NFATC4,PRKCG,FA cytotoxicity S,VAV2,SHC2 rno04350:TGF-beta 9 0.8 0.092978 BMP4,BMP2,CDKN2B,GDF6,S 86 5590 1.924342 signaling pathway MAD6,TGFBR2,TGFB3,THBS2, MYC rno05416:Viral 9 0.8 0.097851 CAV1,CD55,CASP3,SGCG,MY 87 5590 1.902223 myocarditis H2,MYH14,CXADR,MYH7B,SG CB</p>