CENTRAL NERVOUS SYSTEM DEPRESSANTS Opioid Pain Relievers Anxiolytics (also belong to psychiatric medication category) • codeine (in 222® Tablets, Tylenol® No. 1/2/3/4, Fiorinal® C, Benzodiazepines Codeine Contin, etc.) • heroin • alprazolam (Xanax®) • hydrocodone (Hycodan®, etc.) • chlordiazepoxide (Librium®) • hydromorphone (Dilaudid®) • clonazepam (Rivotril®) • methadone • diazepam (Valium®) • morphine (MS Contin®, M-Eslon®, Kadian®, Statex®, etc.) • flurazepam (Dalmane®) • oxycodone (in Oxycocet®, Percocet®, Percodan®, OxyContin®, etc.) • lorazepam (Ativan®) • pentazocine (Talwin®) • nitrazepam (Mogadon®) • oxazepam ( Serax®) Alcohol • temazepam (Restoril®) Inhalants Barbiturates • gases (e.g. nitrous oxide, “laughing gas”, chloroform, halothane, • butalbital (in Fiorinal®) ether) • secobarbital (Seconal®) • volatile solvents (benzene, toluene, xylene, acetone, naptha and hexane) Buspirone (Buspar®) • nitrites (amyl nitrite, butyl nitrite and cyclohexyl nitrite – also known as “poppers”) Non-Benzodiazepine Hypnotics (also belong to psychiatric medication category) • chloral hydrate • zopiclone (Imovane®) Other • GHB (gamma-hydroxybutyrate) • Rohypnol (flunitrazepam) CENTRAL NERVOUS SYSTEM STIMULANTS Amphetamines Caffeine • dextroamphetamine (Dexadrine®) Methelynedioxyamphetamine (MDA) • methamphetamine (“Crystal meth”) (also has hallucinogenic actions) • methylphenidate (Biphentin®, Concerta®, Ritalin®) • mixed amphetamine salts (Adderall XR®) 3,4-Methelynedioxymethamphetamine (MDMA, Ecstasy) (also has hallucinogenic actions) Cocaine/Crack Nicotine Decongestants (alone or in combination with other medications in allergy and cough and cold products) • phenylephrine • pseudoephedrine (Sudafed®) Herbal Stimulants (e.g. ephedra) HALLUCINOGENS Indolealkylamines Cannabinoids (especially “THC”/tetrahydrocannabinol, found in marijuana, hash, • DMT (Dimethyltryptamine, from the bark of the Virola and hash oil) tree, and other sources) (also have CNS depressant activity) • LSD (d-lysergic acid diethylamide, “Acid”) • LSA (d-lysergic amide, from morning Anticholinergics • glory seeds) • psilocybin (“Magic mushrooms”) • deadly nightshade (Atropa belladonna) • jimsonweed (Datura stramonium) • scopolamine (Transderm-V®) Phenylethylamines Arylcycloalkylamines • mescaline (found in peyote cactus) • MDA (Methylenedioxyamphetamine) • ketamine • MDMA (Ecstasy, 3,4-methylenedioxymethamphetamine) • PCP (Phencyclidine) • PMA (Paramethoxyamphetamine) • 2-CB (4-bromo-2,5-dimethoxyphenethylamine) Salvinorin-A (from the plant Salvia divinorum) • STP (2,5-dimethoxy-4-methylamphetamine) • TMA (Trimethoxyamphetamine) PSYCHIATRIC MEDICATIONS Antipsychotics Antidepressants Typical (oral) Tricyclic Antidepressants (TCAs) • chlorpromazine (Largactil®) • amitriptyline (Elavil®) • flupenthixol (Fluanxol) • clomipramine (Anafranil®) • fluphenazine (Modecate®) • desipramine (Norpramin®) • haloperidol (Haldol®) • doxepin • loxapine • imipramine (Tofranil®) • methotrimeprazine (Nozinan®) • nortriptyline (Aventyl®) • perphenazine (Trilafon®) • trimipramine (Surmontil®) • pimozide (Orap®) • trifluoperazine (Stelazine®) Monoamine Oxidase Inhibitors (MAOIs) • zuclopenthixol (Clopixol®) • moclobemide (Manerix®) • phenelzine (Nardil®) Atypical (oral) • tranylcypromine (Parnate®) • aripiprazole (Abilify®) Selective Serotonin Reuptake Inhibitors (SSRIs) • clozapine (Clozaril®) • olanzapine (Zyprexa®/Zyprexa® Zydis/Zyprexa® • citalopram (Celexa®) IntraMuscular) • escitalopram (Cipralex®) • paliperidone extended release tablet (Invega®) • fluoxetine (Prozac®) • quetiapine (Seroquel®/Seroquel® XR) • fluvoxamine (Luvox®) • risperidone (Risperdal®/Risperdal® M-Tab/Risperdal® • paroxetine (Paxil® and Paxil CR®) Oral Solution) • sertraline (Zoloft®) • ziprasidone (Zeldox®) Selective Serotonin and Norepinephrine Reuptake Depot (long-acting) antipsychotic injections Inhibitors (SNRIs) • flupenthixol decanoate (Fluanxol® Depot) • desvenlafaxine (Pristiq®) • fluphenazine decanoate (Modecate® Depot) • duloxetine (Cymbalta®) • haloperidol decanoate (Haldol® Depot) • venlafaxine (Effexor® XR) • paliperidone palmitate long acting injection (Invega® Sustenna) Serotonin-2 Antagonists/Reuptake Inhibitor (SARI) • pipotiazine palmitate (Piportil® Depot) • risperidone (Risperdal® Consta) • trazodone (Desyrel®) • zuclopenthixol acetate (Clopixol® Accuphase) • zuclopenthixol decanoate (Clopixol® Depot) Norepinephrine and Dopamine Reuptake Inhibitors (NDRIs) Antiparkinsonian Agents (for treatment of extrapyramidal side effects of • bupropion SR (Wellbutrin® SR) antipsychotics) • bupropion XL (Wellbutrin® XL) • benztropine (Cogentin®) Noradrenergic/Specific Serotonergic Antidepressants • biperiden (NaSSAs) • ethopropazine • procyclidine (Kemadrin®) • mirtazapine (Remeron®) • trihexyphenidyl (Artane®) • mirtazapine orally disintegrating tablet (Remeron RD®) Non-Benzodiazepine Sedative/Hypnotics (also belong to CNS depressants category) Mood Stabilizers • chloral hydrate • carbamazepine (Tegretol®) • zopiclone (Imovane®) • lamotrigine (Lamictal®) • lithium (Carbolith®) Agents for Alcohol Dependence • topiramate (Topamax®) • valproic acid/divalproex (Epival®) • acamprosate (Campral®) • disulfiram (Antabuse®) Adjunct in the treatment of mood disorders • naltrexone (Revia®) • L-tryptophan (Tryptan®) Agents for Smoking Cessation Anxiolytics • nicotine (patch, gum, lozenge, inhaler) (also belong to the CNS depressants category) • varenicline (Champix®) Benzodiazepines • bupropion SR (Zyban®) • alprazolam (Xanax®) Opioid Substitution Therapy • chlordiazepoxide (Librium®) • clonazepam (Rivotril®) • buprenorphine with naloxone (Suboxone®) • diazepam (Valium®) • methadone • flurazepam (Dalmane®) • lorazepam (Ativan®) Opioid Antagonists • nitrazepam (Mogadon®) • oxazepam ( Serax®) • naloxone (Narcan®) • temazepam (Restoril®) Barbiturates • butalbital (in Fiorinal®) • secobarbital (Seconal®) Buspirone (Buspar®) .