![Table 1. Comparative Analysis of Bce ATCC 14579 and Ban A2012 Based on the Metabolic](https://data.docslib.org/img/3a60ab92a6e30910dab9bd827208bcff-1.webp)
<p>Table 1. Comparative analysis of Bce ATCC 14579 and Ban A2012 based on the metabolic reconstruction. </p><p>@ Carbohydrate_metabolism</p><p>@ Carbohydrate_assimilation</p><p>@ Polysaccharide_degradation</p><p>@ Pullulan_degradation</p><p>* Pullulan_degradation_by_pullulanase</p><p>. 3.2.1.41 - Pullulanase</p><p>BC2734, BA_3251 95% identical</p><p>BC4699, BA_5371 92% identical</p><p>@ Chitin_and_chitosan_degradation</p><p>* Chitosan_degradation</p><p>. Chitosanase (EC 3.2.1.132)</p><p>BC2682, BA_3190 96% identical</p><p>* Chitin_degradation</p><p>. Endochitinase (EC 3.2.1.14)</p><p>BC0429, BA_0961 94% identical</p><p>. Exochitinase (EC 3.2.1.14)</p><p>BC3725, BA_4327 94% identical</p><p>@ Degradation_of_inulin_and_levan</p><p>* Inulin_oligomer_degradation_by_beta-fructosidase</p><p>. 3.2.1.26 - Beta-fructofuranosidase</p><p>BC0774, BA_1337 89% identical</p><p>@ Glycogen_and_starch_degradation</p><p>* Amylose_hydrolysis_via_cyclomaltodextrin</p><p>. 3.2.1.54 - Cyclomaltodextrinase</p><p>BC4014, BA_4691 93% identical * Amylose_hydrolysis_by_maltogenic_alpha-amylase</p><p>. 3.2.1.133 - Glucan 1,4-alpha-maltohydrolase</p><p>BC4014, BA_4691 93% identical</p><p>* Amylose_hydrolysis_by_maltohexaosidase</p><p>. 3.2.1.98 - Glucan 1,4-alpha-maltohexaosidase</p><p>BC3482, BA_4041 95% identical</p><p>* Amylose_hydrolysis_by_alpha-glucosidase</p><p>. 3.2.1.20 - Alpha-glucosidase</p><p>BC0413, BA_0945 95% identical</p><p>* Amylose_hydrolysis_by_alpha-amylase</p><p>. 3.2.1.1 - Alpha-amylase</p><p>BC1157, BA_1706 88% identical</p><p>* Amylose_phosphorolysis</p><p>. 2.4.1.1 - Phosphorylase</p><p>BC4863, BA_5537 95% identical</p><p>* Glycogen_and_amylopectin_hydrolysis_to_limit_dextrin_by_alpha-amylase</p><p>. 3.2.1.1 - Alpha-amylase</p><p>BC1157, BA_1706 88% identical</p><p>* Glycogen_and_amylopectin_phosphorolysis_to_limit_dextrin</p><p>. 2.4.1.1 - Phosphorylase</p><p>BC4863, BA_5537 95% identical</p><p>@ Assimilation_of_oligosaccharides_and_disaccharides</p><p>@ Sucrose_degradation</p><p>* Sucrose_hydrolysis</p><p>. 3.2.1.26 - Beta-fructofuranosidase</p><p>BC0774, BA_1337 89% identical</p><p> or . 3.2.1.48 - Sucrose Alpha-glucosidase * Sucrose-6-phosphate_hydrolysis</p><p>. 3.2.1.26 - Beta-fructofuranosidase</p><p>BC0774, BA_1337 89% identical</p><p>@ Degradation_of_alpha-D-glucosyl-D-fructoses</p><p>* Palatinose_hydrolysis</p><p>. 3.2.1.10 - Oligosaccharide Alpha-1,6-glucosidase</p><p>BC4015, BA_4692 95% identical</p><p>@ Raffinose_degradation</p><p>* Raffinose_degradation_via_beta-fructofuranosidase</p><p>. 3.2.1.26 - Beta-fructofuranosidase</p><p>BC0774, BA_1337 89% identical</p><p>@ Cellobiose_degradation</p><p>* Cellobiose_6-phosphate_hydrolysis_via_6-phospho-beta-glucosidase</p><p>. 3.2.1.86 - 6-phospho-beta-glucosidase</p><p>BC5209, BA_0294 99% identical</p><p>BC3760</p><p>@ Panose_and_isopanose_degradation</p><p>* Panose_hydrolysis_to_glucose_and_maltose</p><p>. 3.2.1.70 - Glucan 1,6-alpha-glucosidase</p><p> or . 3.2.1.10 - Oligosaccharide Alpha-1,6-glucosidase</p><p>BC4015, BA_4692 95% identical</p><p>@ Isomaltose_degradation</p><p>* Isomaltose_hydrolysis</p><p>. 3.2.1.10 - Oligosaccharide Alpha-1,6-glucosidase</p><p>BC4015, BA_4692 95% identical</p><p>@ Maltose_degradation</p><p>* Maltose_acetylation . 2.3.1.79 - Maltose O-acetyltransferase</p><p>BC4658, BA_3901 66% identical</p><p>* Maltose_hydrolysis</p><p>. 3.2.1.20 - Alpha-glucosidase</p><p>BC0413, BA_0945 95% identical</p><p> or . 3.2.1.48 - Sucrose Alpha-glucosidase</p><p>@ Trehalose_degradation</p><p>* Trehalose_6-phosphate_hydrolysis</p><p>. 3.2.1.93 - Alpha,alpha-phosphotrehalase</p><p>BC0632, BA_1215 95% identical</p><p> or . 3.2.1.122 - Maltose-6'-phosphate Glucosidase</p><p>@ Diacetylchitobiose_and_chitobiose_degradation</p><p>* Diacetylchitobiose_uptake_PTS_system</p><p>. PTS system, diacetylchitobiose-specific IIA component (EC 2.7.1.69)</p><p>BC0807, BA_1377 92% identical</p><p>. PTS system, diacetylchitobiose-specific IIB component (EC 2.7.1.69)</p><p>BC2393, BA_2957 95% identical</p><p>BC0808, BA_1378 94% identical</p><p>* Chitobiose-6-phosphate_hydrolysis</p><p>. 3.2.1.86 - 6-phospho-beta-glucosidase</p><p>BC5209, BA_0294 99% identical</p><p>BC3760 </p><p>@ Glucose_and_gluconate_metabolism</p><p>@ Glucose_phosphorylation</p><p>* Glucose_phosphorylation_by_glucokinase</p><p>. 2.7.1.2 - Glucokinase</p><p>BC4260, BA_4934 98% identical * Alpha-phosphoglucomutase_reaction</p><p>. 5.4.2.2 - Phosphoglucomutase</p><p>BC4919, BA_0026 97% identical</p><p>* Glucose-6-phosphate_oxidation_to_6-phosphogluconate</p><p>. 1.1.1.49 - Glucose-6-phosphate 1-dehydrogenase</p><p>BC3375, BA_3931 97% identical</p><p>BC3376, BA_3932 92% identical</p><p>. 3.1.1.31 - 6-phosphogluconolactonase, putative</p><p>BC3368, BA_3925 91% identical</p><p>* D-gluconate_phosphorylation</p><p>. 2.7.1.12 - Gluconokinase</p><p>BC3369, BA_3926 97% identical</p><p>BC2223</p><p>BA_0743, BA_0744 </p><p>* D-glucose_oxidation_by_glucose_1-dehydrogenase</p><p>. 1.1.1.47 - Glucose 1-dehydrogenase</p><p>BC4715, BA_5386 97% identical</p><p>. 3.1.1.17 - Gluconolactonase</p><p>@ D-fructose_metabolism</p><p>* Fructose_phosphorylation_by_fructokinase</p><p>. 2.7.1.4 - Fructokinase</p><p>BC0773, BA_1336 88% identical</p><p>* D-fructose-1-phosphate_phosphorylation</p><p>. 2.7.1.56 - 1-phosphofructokinase</p><p>BC3719, BA_4320 90% identical</p><p>@ Metabolism_of_D-ribose,_2-deoxy-D-ribose_and_ribitol</p><p>* Deoxyribose-phosphate_aldolase . 4.1.2.4 - Deoxyribose-phosphate Aldolase</p><p>BC1820, BA_2394 78% identical</p><p>* Phosphopentomutase_reaction_(deoxyribose)</p><p>. 5.4.2.7 - Phosphopentomutase</p><p>BC4087, BA_4767 98% identical</p><p>* 2-deoxy-D-ribose_phosphorylation_via_ribokinase</p><p>. 2.7.1.15 - Ribokinase</p><p>BC0660, BA_1253 95% identical</p><p>* Ribokinase</p><p>. 2.7.1.15 - Ribokinase</p><p>BC0660, BA_1253 95% identical</p><p>@ Aminosugar_degradation</p><p>@ N-acetylglucosamine_metabolism</p><p>* N-acetylglucosamine_phosphorylation_by N-acetylglucosamine_kinase</p><p>. 2.7.1.59 - N-acetylglucosamine Kinase</p><p>BC2397, BA_2961 79% identical</p><p>* N-acetylglucosamine_6-phosphate_deacetylation</p><p>. 3.5.1.25 - N-acetylglucosamine-6-phosphate Deacetylase</p><p>BC4055, BA_4734 97% identical</p><p>* D-glucosamine_6-phosphate_degradation</p><p>. 3.5.99.6 - Glucosamine-6-phosphate Deaminase</p><p>BC4054, BA_4733 98% identical</p><p>@ Uronic_acid_metabolism</p><p>* 2-dehydro-3-deoxy-D-gluconate_degradation</p><p>. 2.7.1.45 - 2-dehydro-3-deoxygluconokinase</p><p>BC4843, BA_5516 95% identical</p><p>. 4.1.2.14 - 2-dehydro-3-deoxyphosphogluconate Aldolase BC4844, BA_5517 98% identical</p><p>@ Polyol_metabolism</p><p>@ Glycerol_and_dihydroxyacetone_metabolism</p><p>* Dihydroxyacetone_kinase</p><p>. 2.7.1.29 - Glycerone Kinase</p><p>BC0981, BA_1540 97% identical</p><p>BC0979, BA_1538 94% identical</p><p>* Glycerol-3-phosphate_oxidation_to_glycerone-3-phosphate_(NAD(P))</p><p>. 1.1.1.94 - Glycerol-3-phosphate Dehydrogenase (nad(p)+)</p><p>BC1505, BA_2046 96% identical</p><p>. 1.1.1.8 - Glycerol-3-phosphate Dehydrogenase (nad+)</p><p>* Glycerol-3-phosphate_oxidation_to_glycerone-3-phosphate_(FAD)</p><p>. 1.1.99.5 - Glycerol-3-phosphate Dehydrogenase</p><p>BC1036, BA_1587 97% identical</p><p>* Glycerol_catabolism_via_EC_2.7.1.30</p><p>. 2.7.1.30 - Glycerol Kinase</p><p>BC1035, BA_1586 98% identical</p><p>@ Myo-inositol_metabolism</p><p>* D-inositol_1-phosphate_catabolism</p><p>. 3.1.3.25 - Myo-inositol-1(or 4)-monophosphatase</p><p>BC3958, BA_4639 94% identical</p><p>* Myo-inositol_degradation</p><p>. 1.1.1.18 - Myo-inositol 2-dehydrogenase</p><p>BA_3002</p><p>. IolD protein</p><p>BA_3005</p><p>. IolB protein BA_3009</p><p>. IolE protein</p><p>BA_3007</p><p>BA_3005</p><p>. IolH protein</p><p>. IolI protein</p><p>. 2.7.1.92 - 5-dehydro-2-deoxygluconokinase</p><p>BA_3003</p><p>. 4.1.2.29 - 5-dehydro-2-deoxyphosphogluconate Aldolase</p><p>BA_3008</p><p>. 1.2.1.18 - Malonate-semialdehyde Dehydrogenase (acetylating)</p><p>BA_3004</p><p>@ Metabolism_of_alcohols,_aldehydes_and_ketones</p><p>@ Ethanol_and_acetaldehyde_metabolism</p><p>* Ethanol_oxidation_by_alcohol_dehydrogenase</p><p>. 1.1.1.1 - Alcohol Dehydrogenase</p><p>BC2660, BA_3165 89% identical</p><p>BC2220, BA_2770 97% identical</p><p>BC0802, BA_1368 92% identical</p><p>BC4365, BA_5039 96% identical</p><p>* Acetaldehyde_oxidation</p><p>. 1.2.1.3 - Aldehyde Dehydrogenase (nad+)</p><p>BC3555, BA_4101 98% identical</p><p>BC2832, BA_3352 95% identical</p><p> or . 1.2.1.4 - Aldehyde Dehydrogenase (nadp+)</p><p>* Acetaldehyde_oxidation_(CoA-acetylating)</p><p>. 1.2.1.10 - Acetaldehyde Dehydrogenase (acetylating) BC4365, BA_5039 96% identical</p><p>@ Methanol_and_formaldehyde_metabolism</p><p>* Methanol_oxidation_via_alcohol_dehydrogenase</p><p>. 1.1.1.1 - Alcohol Dehydrogenase</p><p>BC2660, BA_3165 89% identical</p><p>BC2220, BA_2770 97% identical</p><p>BC0802, BA_1368 92% identical</p><p>BC4365, BA_5039 96% identical</p><p>* Formate_biosynthesis</p><p>. 1.2.1.1 - Formaldehyde Dehydrogenase (glutathione)</p><p>BC3092, BA_3633 98% identical</p><p>. 3.1.2.12 - S-formylglutathione Hydrolase</p><p>@ Metabolism_of_butane-2,3-diol_and_acetoin</p><p>* Acetoin_dehydrogenase_accessory_proteins</p><p>. Acetoin utilization protein acuA (EC 2.3.1.-)</p><p>BC4660, BA_5335 98% identical</p><p>. Acetoin utilization acuB protein</p><p>BC4661, BA_5336 98% identical</p><p>. Acetoin utilization acuC protein</p><p>BC4662, BA_5337 97% identical</p><p>* (R,R)-butanediol_oxidation_to_acetoin</p><p>. 1.1.1.4 - (r,r)-butanediol Dehydrogenase</p><p>BC0668, BA_1262 98% identical</p><p>* Acetoin_degradation_to_acetyl-CoA</p><p>. 1.2.4.- - Acetoin dehydrogenase E1 component alpha-subunit</p><p>BC2779, BA_3300 98% identical</p><p>. 1.2.4.- - Acetoin dehydrogenase E1 component beta-subunit BC2778, BA_3299 98% identical</p><p>. 2.3.1.- - Dihydrolipoamide acetyltransferase component of acetoin dehydrogenase complex</p><p>BC2777, BA_3298 89% identical</p><p>. 1.8.1.4 - Dihydrolipoamide Dehydrogenase</p><p>BC2776, BA_3297 89% identical</p><p>@ Metabolism_of_carboxylic_acids</p><p>@ Butyrate_metabolism</p><p>* Butanoyl-CoA_biosynthesis_via_butanoyl_phosphate</p><p>. 2.7.2.14 - Branched-chain-fatty-acid Kinase</p><p>BC4161, BA_4841 97% identical</p><p> or . 2.7.2.7 - Butyrate Kinase</p><p>. 2.3.1.19 - Phosphate Butyryltransferase</p><p>BC4163, BA_4843 96% identical</p><p>* Butanoyl-CoA oxidation_via_butyryl-CoA_dehydrogenase</p><p>. 1.3.99.2 - Butyryl-CoA Dehydrogenase</p><p>BC3074, BA_3608 95% identical</p><p>BC5342, BA_0443 97% identical</p><p>BC5341, BA_0442 97% identical</p><p>* Crotonoyl-CoA--acetyl-CoA_metabolism</p><p>. 4.2.1.55 - 3-hydroxybutyryl-coa Dehydratase</p><p>BC0898, BA_1476 98% identical</p><p>. 1.1.1.157 - 3-hydroxybutyryl-coa Dehydrogenase</p><p>BC5343, BA_0444 98% identical</p><p>. 2.3.1.9 - Acetyl-coa Acetyltransferase</p><p>BC5344, BA_0445 99% identical</p><p>@ Propionate_metabolism * Propanoyl-CoA_biosynthesis_via_acetate-CoA_ligase</p><p>. 6.2.1.1 - Acetate--coa Ligase</p><p>BC4659, BA_5334 98% identical</p><p>BC4645, BA_5317 97% identical</p><p>BC2489, BA_3055 97% identical</p><p>* Methylcitrate_pathway</p><p>. 4.1.3.31 - 2-methylcitrate Synthase</p><p>BC2285, BA_2844 99% identical</p><p>. 4.2.1.79 - 2-methylcitrate Dehydratase</p><p>BC2286, BA_2845 99% identical</p><p>. 4.2.1.99 - 2-methylisocitrate Dehydratase</p><p>BC2286, BA_2845 99% identical</p><p>. 4.1.3.30 - Methylisocitrate Lyase</p><p>BC2287, RBAT10010 94% identical </p><p>* (S)-methylmalonyl-CoA_biosynthesis_via_propionyl-CoA_carboxylase</p><p>. 6.4.1.3 - Propionyl-coa Carboxylase</p><p>BC2484, BA_3050 97% identical</p><p>BC2488, BA_3054 98% identical</p><p>* Methylmalonyl-CoA_epimerase</p><p>. 5.1.99.1 - Methylmalonyl-coa Epimerase</p><p>BC1837, BA_2415 97% identical</p><p>@ D-lactate_and_L-lactate_metabolism</p><p>* L-lactate_dehydrogenase</p><p>. 1.1.1.27 - L-lactate Deydrogenase</p><p>BC4996, BA_0106 99% identical</p><p>BC1924, BA_2427 99% identical</p><p>BC1519 * D-lactate_oxidation_by_(S)-hydroxy-acid_oxidase</p><p>. 1.1.3.15 - (s)-2-hydroxy-acid Oxidase</p><p>BC1296, BA_1834 96% identical</p><p>BC1297, BA_1835 97% identical</p><p>BC1303, BA_1841 98% identical</p><p>BC3504, BA_4067 93% identical</p><p>@ Glycolate_oxidation</p><p>* Glyoxylate_reductase</p><p>. 1.1.1.79 - Glyoxylate Reductase (nadp+)</p><p>BC1415, BA_1955 95% identical</p><p>. 1.1.1.26 - Glycolate Reductase</p><p>BC1415, BA_1955 95% identical</p><p>* Glyoxylate_oxidation_by_(S)-hydroxy-acid_oxidase</p><p>. 1.1.3.15 - (s)-2-hydroxy-acid Oxidase</p><p>BC1296, BA_1834 96% identical</p><p>BC1297, BA_1835 97% identical</p><p>BC1303, BA_1841 98% identical</p><p>BC3504, BA_4067 93% identical</p><p>@ Acetate_assimilation</p><p>* Acetyl-CoA_biosynthesis_via_acetate--CoA_ligase</p><p>. 6.2.1.1 - Acetate--coa Ligase</p><p>BC4659, BA_5334 98% identical</p><p>BC4645, BA_5317 97% identical</p><p>BC2489, BA_3055 97% identical</p><p>* Acetyl-CoA_catabolism_via_acetyl_phosphate</p><p>. 2.7.2.1 - Acetate Kinase</p><p>BC4637, BA_5309 98% identical . 2.3.1.8 - Phosphate Acetyltransferase</p><p>BC5387, BA_0493 99% identical</p><p>* 3-phosphoglycerate_anabolism</p><p>. 2.7.1.31 - Glycerate Kinase</p><p>BC0184, BA_0734 84% identical</p><p>* Oxalate_decarboxylation</p><p>. 4.1.1.2 - Oxalate Decarboxylase</p><p>BC2383, BA_2948 87% identical</p><p>BC1031</p><p>BA_2254</p><p>@ Carbohydrate_membrane_transport</p><p>* PTS_system_general_components</p><p>. 2.7.3.9 - Phosphoenolpyruvate--protein Phosphatase</p><p>BC4048, BA_4726 98% identical</p><p>. Phosphocarrier protein HPr</p><p>BC4049, BA_4727 100% identical</p><p>@ Oligosaccharides_membrane_transport</p><p>* Beta-cyclodextrin_uptake_via_cyclodextrin_ABC_transporter</p><p>* Alpha-cyclodextrin_uptake_via_cyclodextrin_ABC_transporter</p><p>* Linear_maltodextrin_uptake_via_cyclodextrin_ABC_transporter</p><p>* Gamma-cyclodextrin_uptake_via_cyclodextrin_ABC_transporter</p><p>. Cyclodextrin-binding protein</p><p>BC4013, BA_4690 95% identical</p><p>. Cyclodextrin transport system permease protein</p><p>BC4012, BA_4689 98% identical</p><p>BC4011, BA_4688 100% identical</p><p>* Lichenan_oligosaccharide_uptake_lic_PTS_system . PTS system, lichenan oligosaccharide-specific IIA component (EC 2.7.1.69)</p><p>BC5215, BA_0300 98% identical</p><p>BC5210, BA_0295 98% identical</p><p>. PTS system, lichenan oligosaccharide-specific IIB component (EC 2.7.1.69)</p><p>BC5217, BA_0302 97% identical</p><p>. PTS system, lichenan oligosaccharide-specific IIC component</p><p>BC5211, BA_0296 99% identical</p><p>@ Monosaccharide_membrane_transport</p><p>@ Glucose_membrane_transport</p><p>* Glucose_uptake_glcBC_PTS_forming_glucose-6-phosphate</p><p>. PTS system, glucose-specific IIA component (EC 2.7.1.69)</p><p>BC5320, BA_0418 99% identical</p><p>. PTS system, glucose-specific IIBC component (EC 2.7.1.69)</p><p>* D-glucose_uptake_glucose_transporter_glcU</p><p>. Glucose uptake protein</p><p>BC4716, BA_5387 97% identical</p><p>BC0219, BA_0780 99% identical</p><p>@ D-fructose_membrane_transport</p><p>* D-fructose_uptake_FruABC_PTS_system</p><p>. PTS system, fructose-specific IIABC component (EC 2.7.1.69)</p><p>BC3718, BA_4319 94% identical</p><p>@ N-acetylglucosamine_membrane_transport</p><p>* N-acetylglucosamine_uptake_nag_PTS_forming_GlcNAc-6-phosphate</p><p>. PTS system, N-acetylglucosamine-specific IIABC component (EC 2.7.1.69)</p><p>BC0482, BA_1071 88% identical</p><p>@ Ribose_membrane_transport</p><p>* D-ribose_uptake_ribose_ABC_transporter . D-ribose-binding protein</p><p>BC0664, BA_1257 97% identical</p><p>. Ribose transport system permease protein rbsC</p><p>BC2961, BA_3482 95% identical</p><p>BC0663, BA_1256 98% identical</p><p>. Ribose transport ATP-binding protein rbsA</p><p>BC2963, BA_3484 94% identical</p><p>. High affinity ribose transport protein rbsD</p><p>BC0661, BA_1254 96% identical</p><p>@ Carbohydrate_efflux</p><p>* Formate_channel</p><p>. Formate Transporter</p><p>BC3727, BA_4331 93% identical</p><p>BC3568, BA_4115 94% identical</p><p>@ Aldonic_Uronic_acids_membrane_transport</p><p>* D-gluconate_uptake_proton_symport_gluconate_permease</p><p>. Gluconate permease</p><p>BC4841, BA_5514 98% identical</p><p>BC3370, BA_3927 98% identical</p><p>@ Disaccharides_membrane_transport</p><p>* Diacetylchitobiose_uptake_PTS_system</p><p>. PTS system, diacetylchitobiose-specific IIA component (EC 2.7.1.69)</p><p>BC0807, BA_1377 92% identical</p><p>. PTS system, diacetylchitobiose-specific IIB component (EC 2.7.1.69)</p><p>BC2393, BA_2957 95% identical</p><p>BC0808, BA_1378 94% identical</p><p>. PTS system, diacetylchitobiose-specific IIC component @ Trehalose_membrane_transport</p><p>* Trehalose_uptake_glv_PTS_forming_trehalose-6-phosphate</p><p>. PTS system, glucose-specific IIA component (EC 2.7.1.69)</p><p>BC5320, BA_0418 99% identical</p><p>. PTS system, maltose-specific IIBC component (EC 2.7.1.69)</p><p>* Trehalose_uptake,_PTS_system</p><p>. PTS system, glucose-specific IIA component (EC 2.7.1.69)</p><p>BC5320, BA_0418 99% identical</p><p>. PTS system, trehalose-specific IIBC component (EC 2.7.1.69)</p><p>BC0631, BA_1214 98% identical</p><p>@ Sucrose_membrane_transport</p><p>* Sucrose_uptake,_PTS_system</p><p>. PTS system, glucose-specific IIA component (EC 2.7.1.69)</p><p>BC5320, BA_0418 99% identical</p><p>. PTS system, sucrose-specific IIBC component (EC 2.7.1.69)</p><p>BC0842, BA_1410 96% identical</p><p>@ Cellobiose_membrane_transport</p><p>* Cellobiose_uptake_lic_PTS_forming_cellobiose-6-phosphate</p><p>. PTS system, lichenan oligosaccharide-specific IIA component (EC 2.7.1.69)</p><p>BC5215, BA_0300 98% identical</p><p>BC5210, BA_0295 98% identical</p><p>. PTS system, lichenan oligosaccharide-specific IIB component (EC 2.7.1.69)</p><p>BC5217, BA_0302 97% identical</p><p>. PTS system, lichenan oligosaccharide-specific IIC component</p><p>BC5211, BA_0296 99% identical</p><p>@ Salicin_membrane_transport</p><p>* Salicin_uptake_lic_PTS_forming_salicin-6-phosphate . PTS system, lichenan oligosaccharide-specific IIA component (EC 2.7.1.69)</p><p>BC5215, BA_0300 98% identical</p><p>BC5210, BA_0295 98% identical</p><p>. PTS system, lichenan oligosaccharide-specific IIB component (EC 2.7.1.69)</p><p>BC5217, BA_0302 97% identical</p><p>. PTS system, lichenan oligosaccharide-specific IIC component</p><p>BC5211, BA_0296 99% identical</p><p>@ Arbutin_membrane_transport</p><p>* Arbutin_uptake_lic_PTS_forming_arbutin-6-phosphate</p><p>. PTS system, lichenan oligosaccharide-specific IIA component (EC 2.7.1.69)</p><p>BC5215, BA_0300 98% identical</p><p>BC5210, BA_0295 98% identical</p><p>. PTS system, lichenan oligosaccharide-specific IIB component (EC 2.7.1.69)</p><p>BC5217, BA_0302 97% identical</p><p>. PTS system, lichenan oligosaccharide-specific IIC component</p><p>BC5211, BA_0296 99% identical</p><p>@ Polyols_membrane_transport</p><p>@ Glycerol_3-phosphate_membrane_transport</p><p>* Glycerol-3-phosphate_uptake_ABC_transporter</p><p>. Glycerol-3-phosphate-binding protein</p><p>BC0570, BA_1149 84% identical</p><p>. SN-glycerol-3-phosphate transport system permease protein ugpA</p><p>BC0568, BA_1145 73% identical</p><p>. SN-glycerol-3-phosphate transport system permease protein ugpE</p><p>BC0569, BA_1147 98% identical</p><p>. SN-glycerol-3-phosphate transport ATP-binding protein ugpC</p><p>* Glycerol-3-P_phosphate_antiport_glpT . Glycerol-3-phosphate transporter</p><p>BC0656, BA_1247 98% identical</p><p>* Glycerol_uptake_channel</p><p>. Glycerol uptake facilitator protein</p><p>BC1034, BA_1585 86% identical</p><p>@ Carboxylic_acids_membrane_transport</p><p>* Anaerobic_fumarate_uptake_succinate_antiport</p><p>. Anaerobic C4-dicarboxylate transporter</p><p>BC0421, BA_0954 99% identical</p><p>* Anaerobic_fumarate_uptake_proton_symport</p><p>. Anaerobic C4-dicarboxylate transporter</p><p>BC0421, BA_0954 99% identical</p><p>@ Citrate_membrane_transport</p><p>* Citrate_uptake_proton_symport</p><p>. Citrate-proton symporter</p><p>BC0562, BA_1139 94% identical</p><p>BC0935, BA_1501 98% identical</p><p>* L-lactate_uptake_proton_symport_L-lactate_permease</p><p>* Glycolate_uptake_proton_symport_L-lactate_permease</p><p>* D-lactate_uptake_proton_symport_L-lactate_permease</p><p>. L-lactate permease</p><p>BC0612, BA_1194 91% identical</p><p>BC1240, BA_1789 96% identical</p><p>@ Bacterial_Protein_Metabolism</p><p>@ Bacterial_Protein_Degradation</p><p>@ Bacterial_metallopeptidases * Bacterial_metallopeptidases</p><p>. 3.4.24.3 - Microbial Collagenase</p><p>BC4377, BA_5051 95% identical</p><p>BC3529, BA_4075 94% identical</p><p>BC0556, BA_1129 93% identical</p><p>BC3762, BA_4363 90% identical</p><p>BC3161, BA_3802 92% identical</p><p>BC3412</p><p>BC2466</p><p>BC3009</p><p>BC3010</p><p>. 3.4.24.28 - Bacillolysin</p><p>BC2735, BA_3252 95% identical</p><p>BC0602, BA_1181 95% identical</p><p>BC5036, BA_0144 94% identical</p><p>BC3383, BA_3938 94% identical</p><p>BC5351</p><p>BC2167, BA_2678 93% identical</p><p>BC2506, BA_3074 82% identical</p><p>. 3.4.24.57 - O-sialoglycoprotein Endopeptidase</p><p>BC0289, BA_0832 97% identical</p><p>. Immune inhibitor A precursor (ec 3.4.24.-)</p><p>BC1284, BA_1822 96% identical</p><p>BC0666, BA_1259 96% identical</p><p>BC2984</p><p>. Membrane metalloprotease</p><p>BC5377, BA_0481 91% identical BC1446, BA_1986 84% identical</p><p>BC3818, BA_4428 94% identical</p><p>. Oligoendopeptidase F (ec 3.4.24.-)</p><p>BC5453, BA_0564 91% identical</p><p>BC1338, BA_1880 90% identical</p><p>BC1193, BA_1742 97% identical</p><p>BC2870, BA_3391 85% identical</p><p>BC2524, BA_3093 95% identical</p><p>BC3484, BA_4043 92% identical</p><p>BA_3346</p><p>. Zinc metalloprotease (ec 3.4.24.-)</p><p>BC0369, BA_0908 95% identical</p><p>BC1123, BA_1672 94% identical</p><p>BC0268, BA_0826 85% identical</p><p>. Zinc Protease (ec 3.4.99.-)</p><p>BC3803, BA_4413 98% identical</p><p>BC3786, BA_4393 95% identical</p><p>BC3787, BA_4394 98% identical</p><p>. Cell envelope-bound metalloprotease (camelysin) (ec 3.4.24.-)</p><p>BC1281, BA_1819 94% identical</p><p>BC4868</p><p>@ Bacterial_Serine_proteases</p><p>* Bacterial_serine_proteases</p><p>. 3.4.21.19 - Glutamyl Endopeptidase</p><p>BC0789</p><p>. 3.4.21.26 - Prolyl Oligopeptidase</p><p>BC2927, BA_4352 78% identical . 3.4.21.53 - Endopeptidase La</p><p>BC3926, BA_4603 92% identical</p><p>BC4478, BA_5142 98% identical</p><p>BC4477, BA_5141 98% identical</p><p>. 3.4.21.66 - Thermitase</p><p>BC2316, BA_2875 96% identical</p><p>BC3240</p><p>. 3.4.21.89 - Signal Peptidase I</p><p>BC1136, BA_1687 93% identical</p><p>BC3060, BA_3591 89% identical</p><p>BC3837, BA_4447 68% identical</p><p>BC3070, BA_3602 97% identical</p><p>BC0456, BA_0989 90% identical</p><p>BC1278, BA_1816 94% identical</p><p>BC2621</p><p>. 3.4.21.92 - Endopeptidase Clp</p><p>BC2793, BA_3310 96% identical</p><p>BC5152, BA_0238 99% identical</p><p>BA_4564</p><p>. ATP-dependent protease hslV (ec 3.4.25.-)</p><p>BC3828, BA_4438 100% identical</p><p>. ATP-dependent hsl protease ATP-binding subunit hslU</p><p>BC3827, BA_4437 98% identical</p><p>. Minor extracellular protease VPR precursor (ec 3.4.21.-)</p><p>BC4351, BA_5024 92% identical</p><p>BC4869</p><p>. Protease Do (ec 3.4.21.-) BC5458, BA_0568 95% identical</p><p>. Serine Protease (ec 3.4.21.-)</p><p>BC0759, BA_1330 98% identical</p><p>BC3927, BA_4604 96% identical</p><p>BC2704, BA_3217 91% identical</p><p>. Protease Hhoa (ec 3.4.21.-)</p><p>BC3600, BA_4148 97% identical</p><p>@ Bacterial_Exopeptidases</p><p>@ Bacterial_Omega_peptidases</p><p>* Bacterial_omega_peptidases</p><p>. 3.4.19.1 - Acylaminoacyl-peptidase</p><p>BC0192, BA_0747 85% identical</p><p>. 3.4.19.3 - Pyroglutamyl-peptidase I</p><p>BC3063, BA_3595 94% identical</p><p>@ Bacterial_Carboxy_peptidases</p><p>* Bacterial_carboxy_peptidases</p><p>. 3.4.13.3 - Xaa-his Dipeptidase</p><p>BC2439, BA_2989 94% identical</p><p>BC4702, BA_5374 94% identical</p><p>. 3.4.13.9 - Xaa-pro Dipeptidase</p><p>BC4614, BA_5282 99% identical</p><p>BC4198, BA_4875 98% identical</p><p>BC5199, BA_0284 96% identical</p><p>BC3875, BA_4485 90% identical</p><p>. 3.4.13.19 - Membrane Dipeptidase</p><p>BC3775, BA_4381 92% identical</p><p>. 3.4.17.19 - Thermostable Carboxypeptidase 1 BC1566, BA_2104 97% identical</p><p>@ Bacterial_Amino_peptidases</p><p>* Bacterial_amino_peptidases</p><p>. 3.4.11.1 - Leucyl Aminopeptidase</p><p>BC4921, BA_0028 96% identical</p><p>. 3.4.11.5 - Prolyl Aminopeptidase</p><p>BC2171, BA_2719 93% identical</p><p>BC4663</p><p>BC2337</p><p>BA_3206</p><p>. 3.4.11.9 - Xaa-pro Aminopeptidase</p><p>BC1828, BA_2405 91% identical</p><p>. 3.4.11.18 - Methionyl Aminopeptidase</p><p>BC5356, BA_0458 98% identical</p><p>BC0153, BA_0715 100% identical</p><p>BC1568, BA_2107 89% identical</p><p>. 3.4.14.11 - Xaa-pro Dipeptidyl-peptidase</p><p>BC2861, BA_3381 87% identical</p><p>. Aminopeptidase (EC 3.4.11.-)</p><p>BC4678, BA_5352 98% identical</p><p>BC0360, BA_0899 96% identical</p><p>BC1812</p><p>. Aminopeptidase Y (EC 3.4.11.-)</p><p>BC5359, BA_0463 93% identical</p><p>. Deblocking aminopeptidase (EC 3.4.11.-)</p><p>BC0901, BA_1479 97% identical</p><p>BC4693, BA_5365 98% identical BC4571, BA_5240 98% identical</p><p>. Peptidase T (EC 3.4.11.-)</p><p>BC3743, BA_4347 95% identical</p><p>BC4143, BA_4824 98% identical</p><p>@ Amino_acid_membrane_transport</p><p>@ Gln_Asn_uptake</p><p>* L-glutamine_uptake_Gln_ABC_transporter</p><p>. Glutamine-binding protein</p><p>BC0640, BA_1224 98% identical</p><p>. Glutamine transport system permease protein glnP</p><p>BC0642, BA_1226 96% identical</p><p>. Glutamine transport ATP-binding protein glnQ</p><p>BC0639, BA_1223 95% identical</p><p>@ Ser_Thr_uptake</p><p>* Serine_uptake_proton_symport_sdaC</p><p>. Serine transporter</p><p>BC3398, BA_3947 99% identical</p><p>BC3189, BA_3808 92% identical</p><p>* L-threonine_uptake_LIVTA_ABC_transporter</p><p>. Leucine-, isoleucine-, valine-, threonine-, and alanine-binding protein</p><p>BC1927, BA_2434 96% identical</p><p>. Branched-chain amino acid transport system permease protein livH</p><p>BC1930, BA_2437 97% identical</p><p>. Branched-chain amino acid transport system permease protein livM</p><p>BC1931, BA_2438 97% identical</p><p>. Branched-chain amino acid transport ATP-binding protein livG</p><p>BC1928, BA_2435 95% identical . Branched-chain amino acid transport ATP-binding protein livF</p><p>BC1929, BA_2436 92% identical</p><p>@ Cys_Met_uptake</p><p>* Cystine_uptake_cystine_ABC_transporter</p><p>. Cystine-binding protein</p><p>BC0402, BA_0941 95% identical</p><p>. Cystine transport system permease protein</p><p>BC0873, BA_1436 99% identical</p><p>. Cystine transport ATP-binding protein</p><p>BC0874, BA_1437 98% identical</p><p>@ Ala_Gly_Pro_uptake</p><p>* L-alanine_uptake_proton_symport_acp</p><p>. Sodium/proton-dependent alanine carrier protein</p><p>BC2831, BA_3351 94% identical</p><p>BC0638, BA_1222 98% identical</p><p>BC5043, BA_0150 96% identical</p><p>* Glycine_uptake_sodium_symport_AHdagA</p><p>. Na(+)-linked D-alanine glycine permease</p><p>BC2317, BA_2876 98% identical</p><p>* D-alanine_uptake_sodium_symport_AHdagA</p><p>. Na(+)-linked D-alanine glycine permease</p><p>BC2317, BA_2876 98% identical</p><p>@ Glu_Asp_uptake</p><p>* L-glutamate_uptake_proton_sodium_symport_gltT</p><p>. Proton/sodium-glutamate symport protein</p><p>BC1389, BA_1930 97% identical</p><p>BC1739, BA_2304 98% identical BC4242, BA_4917 85% identical</p><p>BC5218, BA_0303 99% identical</p><p>BC1432, BA_1972 98% identical</p><p>* L-aspartate_uptake_proton_sodium_symport_gltT</p><p>. Proton/sodium-glutamate symport protein</p><p>BC1389, BA_1930 97% identical</p><p>BC1739, BA_2304 98% identical</p><p>BC4242, BA_4917 85% identical</p><p>BC5218, BA_0303 99% identical</p><p>BC1432, BA_1972 98% identical</p><p>@ Polyamine_transport</p><p>* Putrescine_uptake_spermidine-putrescine_ABC_transporter</p><p>* Spermidine_uptake_spermidine-putrescine_ABC_transporter</p><p>. Spermidine/putrescine-binding protein</p><p>BC1289, BA_1827 95% identical</p><p>. Spermidine/putrescine transport system permease protein potB</p><p>BC1287, BA_1825 95% identical</p><p>. Spermidine/putrescine transport system permease protein potC</p><p>BC1288, BA_1826 97% identical</p><p>. Spermidine/putrescine transport ATP-binding protein potA</p><p>BC1286, BA_1824 98% identical</p><p>@ Lys_Arg_Orn_uptake</p><p>* Diaminopimelate_uptake_cystine_ABC_transporter</p><p>. Cystine-binding protein</p><p>BC0402, BA_0941 95% identical</p><p>. Cystine transport system permease protein</p><p>BC0873, BA_1436 99% identical . Cystine transport ATP-binding protein</p><p>BC0874, BA_1437 98% identical</p><p>* L-arginine_uptake_L-ornithine_antiport</p><p>. Arginine/ornithine antiporter</p><p>BC0865, BA_1428 98% identical</p><p>BC2234, BA_2786 94% identical</p><p>BC0629, BA_1212 96% identical</p><p>* L-lysine_uptake_proton_symport_lysine_permease</p><p>. Lysine-specific permease</p><p>BC3052, BA_3583 98% identical</p><p>@ Leu_Ile_Val_uptake</p><p>* L-leucine_uptake_proton_symport_Leu-Ile-Val_transporter</p><p>. Branched-chain amino acid transport system carrier protein</p><p>BC0685, BA_1278 76% identical</p><p>BC1836, BA_3643 70% identical</p><p>BC1441, BA_1981 96% identical</p><p>* L-isoleucine_uptake_proton_symport_Leu-Ile-Val_transporter</p><p>. Branched-chain amino acid transport system carrier protein</p><p>BC0685, BA_1278 76% identical</p><p>BC1836, BA_3643 70% identical</p><p>BC1441, BA_1981 96% identical</p><p>* L-valine_uptake_proton_symport_Leu-Ile-Val_transporter</p><p>. Branched-chain amino acid transport system carrier protein</p><p>BC0685, BA_1278 76% identical</p><p>BC1836, BA_3643 70% identical</p><p>BC1441, BA_1981 96% identical</p><p>@ Peptide_uptake * Tripeptide_uptake_proton_symport_PTR2</p><p>. Di-/tripeptide transporter</p><p>BC0684, BA_1277 98% identical</p><p>* Dipeptide_uptake_proton_symport_PTR2</p><p>. Di-/tripeptide transporter</p><p>BC0684, BA_1277 98% identical</p><p>* Oligopeptide_uptake_opp_ABC_transporter</p><p>. Oligopeptide-binding protein oppA</p><p>BC3585, BA_4131 89% identical</p><p>BC0215, BA_0775 98% identical</p><p>BC0211, BA_0771 96% identical</p><p>BC1794, BA_2372 88% identical</p><p>BC0241, BA_0798 78% identical</p><p>BC2884, BA_3402 74% identical</p><p>BC0216, BA_0776 98% identical</p><p>BC2848, BA_3371 96% identical</p><p>BC0907, BA_1491 97% identical</p><p>BC1185, BA_1728 62% identical</p><p>BC0859, BA_1422 95% identical</p><p>BC2026, BA_2541 95% identical</p><p>. Oligopeptide transport system permease protein oppB</p><p>BC0242, BA_0799 88% identical</p><p>BC2326, BA_2890 96% identical</p><p>BC0908, BA_1492 96% identical</p><p>BC2222, BA_2772 91% identical</p><p>BC0818, BA_1387 94% identical</p><p>BC1180, BA_1729 97% identical . Oligopeptide transport system permease protein oppC</p><p>BC2327, BA_2891 91% identical</p><p>BC0909, BA_1493 97% identical</p><p>BC2221, BA_2771 92% identical</p><p>BC0819, BA_1388 95% identical</p><p>BC1181, BA_1730 98% identical</p><p>. Oligopeptide transport ATP-binding protein oppD</p><p>BC1182, BA_1731 99% identical</p><p>. Oligopeptide transport ATP-binding protein oppF</p><p>BC0210, BA_0770 98% identical</p><p>BC1183, BA_1732 99% identical</p><p>* Amino_acid_uptake,_unknown_specificity,_proton_symport</p><p>. Amino acid permease</p><p>BC0837, BA_1404 98% identical</p><p>BC3245, BA_3819 100% identical</p><p>BC3455, BA_4016 98% identical</p><p>BC1807, BA_2387 97% identical</p><p>BC5013, BA_0124 97% identical</p><p>@ Amino_acid_catabolism</p><p>@ Degradation_of_aromatic_amino_acids</p><p>@ Tryptophan_degradation</p><p>* Tryptophan_dioxygenase</p><p>. 1.13.11.11 - Tryptophan 2,3-dioxygenase</p><p>BC2757, BA_3277 98% identical</p><p>* Arylformamidase</p><p>. 3.5.1.9 - Arylformamidase sequence not known</p><p>@ Kynurenine_degradation * L-kynurenine_hydrolysis</p><p>. 3.7.1.3 - Kynureninase</p><p>BC2759, BA_3279 95% identical</p><p>@ Degradation_of_glutamate,_glutamine,_lysine,_proline_and_arginine</p><p>@ Lysine_degradation</p><p>* L-lysine_2,3-aminomutase</p><p>. 5.4.3.2 - Lysine 2,3-aminomutase</p><p>BC2251, BA_2804 99% identical</p><p>* L-beta-lysine_degradation_via_beta-lysine_acetyltransferase_(putative)</p><p>. Beta-lysine acetyltransferase (EC 2.3.1.-)</p><p>BC2249, BA_2802 93% identical</p><p>. 6-acetamido-3-oxohexanoate aminotransferase (EC 2.6.1.-)</p><p>BC2245, BA_2798 98% identical</p><p>. Putative 3-keto-6-acetamidohexanoate cleavage enzyme (EC 2.3.-.-)</p><p>BC2247, BA_2800 96% identical</p><p>BC2246, BA_2799 98% identical</p><p>. 4-acetamidobutyryl-CoA deacetylase-thioesterase (EC 3.-.-.-)</p><p>BC2248, BA_2801 95% identical</p><p>@ Arginine_degradation</p><p>* Arginine_utilization_regulation</p><p>. Arginine utilization regulatory protein rocR</p><p>BC0473, BA_1064 92% identical</p><p>* Arginase</p><p>. 3.5.3.1 - Arginase</p><p>BC0185, BA_0735 96% identical</p><p>* Arginine_degradation_via_arginine_deiminase</p><p>. 3.5.3.6 - Arginine Deiminase BC0406</p><p>. 2.1.3.3 - Ornithine Carbamoyltransferase</p><p>BC0407</p><p>BC4126, BA_4808 96% identical</p><p>@ Ornithine_degradation</p><p>@ D-ornithine_deamination</p><p>* D-ornithine_deamination_via_D-alanine_transaminase</p><p>. 2.6.1.21 - D-alanine Aminotransferase</p><p>BC2209, BA_2758 91% identical</p><p>BC5233, BA_0320 73% identical</p><p>* D-ornithine_oxidative_deamination</p><p>. 1.4.99.1 - D-amino-acid Dehydrogenase</p><p>BC2723, BA_3236 95% identical</p><p> or . 1.4.3.3 - D-amino Acid Oxidase</p><p>* Ornithine_degradation_via_ornithine_cyclodeaminase</p><p>. 4.3.1.12 - Ornithine Cyclodeaminase</p><p>BC0906, BA_1484 86% identical</p><p>* Ornithine--glutamate_degradation</p><p>. 2.6.1.13 - Ornithine--oxo-acid Aminotransferase</p><p>BC1149, BA_1699 98% identical</p><p>. 1.5.1.12 - 1-pyrroline-5-carboxylate Dehydrogenase</p><p>BC5006, BA_0116 99% identical</p><p>@ L-proline_and_D-proline_degradation</p><p>* 4-hydroxy-D-proline_degradation</p><p>. 1.4.99.1 - D-amino-acid Dehydrogenase</p><p>BC2723, BA_3236 95% identical</p><p> or . D-proline oxidase (EC 1.4.-.-) or . 1.4.3.3 - D-amino Acid Oxidase</p><p>. 3.5.4.22 - 1-pyrroline-4-hydroxy-2-carboxylate Deaminase</p><p>* 4-hydroxy-L-proline_degradation</p><p>. 1.5.1.12 - 1-pyrroline-5-carboxylate Dehydrogenase</p><p>BC5006, BA_0116 99% identical</p><p>. 1.5.1.2 - Pyrroline-5-carboxylate Reductase</p><p>BC4134, BA_4817 93% identical</p><p>BC3109, BA_3644 92% identical</p><p>BC0218, BA_0778 93% identical</p><p>. 2.6.1.23 - 4-hydroxyglutamate Aminotransferase sequence not known</p><p>. 2.6.1.1 - Aspartate Aminotransferase</p><p>BC2896, BA_3415 94% identical</p><p>BC4035, BA_4713 96% identical</p><p>BC4906, BA_0012 93% identical</p><p>. 4.1.3.16 - 4-hydroxy-2-oxoglutarate Aldolase</p><p>BC4844, BA_5517 98% identical</p><p>* Proline_racemase</p><p>. 5.1.1.4 - Proline Racemase</p><p>BC2834, BA_3354 92% identical</p><p>BC2835, BA_3355 89% identical</p><p>BC0905, BA_1483 94% identical</p><p>* D-proline_oxidation</p><p>. D-proline oxidase (EC 1.4.-.-)</p><p> or . 1.4.99.1 - D-amino-acid Dehydrogenase</p><p>BC2723, BA_3236 95% identical</p><p> or . 1.4.3.3 - D-amino Acid Oxidase</p><p>* Proline--glutamate_degradation . 1.5.99.8 - Proline Dehydrogenase</p><p>BC5006, BA_0116 99% identical</p><p>. 1.5.1.12 - 1-pyrroline-5-carboxylate Dehydrogenase</p><p>BC5006, BA_0116 99% identical</p><p>@ Glutamine_deamination</p><p>* L-glutamine_degradation_via_glutaminase</p><p>. 3.5.1.2 - Glutaminase</p><p>BC3115, BA_3658 99% identical</p><p>BC0481, BA_1070 98% identical</p><p>@ Glutamate_degradation</p><p>* L-glutamate-D-glutamate.anabolism</p><p>. 5.1.1.3 - Glutamate Racemase</p><p>BC0866, BA_1429 93% identical</p><p>BC4496, BA_5151 99% identical</p><p>@ D-glutamate_degradation</p><p>* D-alanine_aminotransferase</p><p>. 2.6.1.21 - D-alanine Aminotransferase</p><p>BC2209, BA_2758 91% identical</p><p>BC5233, BA_0320 73% identical</p><p>* Gamma-aminobutyrate_shunt</p><p>. 4.1.1.15 - Glutamate Decarboxylase</p><p> or . 4.1.1.19 - Arginine Decarboxylase</p><p>BC0035, BA_0617 87% identical</p><p>BC3962, BA_4643 94% identical</p><p>. 2.6.1.19 - 4-aminobutyrate Aminotransferase</p><p>BC0355, BA_0895 96% identical</p><p>. 1.2.1.16 - Succinate-semialdehyde Dehydrogenase (nad(p)+) BC0357, BA_0897 97% identical</p><p>BC2241, BA_2794 93% identical</p><p>@ Degradation_of_cysteine,_serine_and_alanine</p><p>@ Serine_degradation</p><p>* L-serine_transamination</p><p>. 2.6.1.51 - Serine--pyruvate Aminotransferase</p><p>BC2399, BA_2963 88% identical</p><p> or . 2.6.1.45 - Serine--glyoxylate Aminotransferase</p><p>* L-serine_deamination</p><p>. 4.2.1.13 - L-serine Dehydratase</p><p>BC4135, BA_4818 99% identical</p><p>BC4136, BA_4819 97% identical</p><p>. 4.2.1.16 - Threonine Dehydratase</p><p>BC2400, RBAT10057 82% identical</p><p>BC1781, BA_2357 96% identical</p><p>* L-serine_racemization</p><p>. Serine racemase (EC 5.1.1.-)</p><p> or . 5.1.1.10 - Amino-acid Racemase</p><p> or . 5.1.1.1 - Alanine Racemase</p><p>BC0264, BA_0822 96% identical</p><p>BC2063, BA_2575 94% identical</p><p>* D-serine--pyruvate,_NH(,3)_catabolism_(cytosol)</p><p>. 4.2.1.14 - D-serine Dehydratase</p><p>BC1725, BA_2290 90% identical</p><p>@ Alanine_degradation</p><p>@ L-alanine_degradation</p><p>* L-alanine_oxidative_deamination . 1.4.1.1 - Alanine Dehydrogenase</p><p>BC4623, BA_5294 99% identical</p><p>BC0592, BA_1174 100% identical</p><p>* L-alanine--D-alanine_anabolism</p><p>. 5.1.1.1 - Alanine Racemase</p><p>BC0264, BA_0822 96% identical</p><p>BC2063, BA_2575 94% identical</p><p>@ D-alanine_degradation</p><p>* D-alanine_aminotransferase</p><p>. 2.6.1.21 - D-alanine Aminotransferase</p><p>BC2209, BA_2758 91% identical</p><p>BC5233, BA_0320 73% identical</p><p>* D-alanine_degradation_D-amino_acid_dehydrogenase</p><p>. 1.4.99.1 - D-amino-acid Dehydrogenase</p><p>BC2723, BA_3236 95% identical</p><p>@ Cysteine_desulfuration</p><p>* Cysteine--pyruvate,_sulfide,_NH(,3)_catabolism</p><p>. 4.4.1.8 - Cystathionine Beta-lyase</p><p>BC4366, BA_5041 98% identical</p><p>BC4254, BA_4928 96% identical</p><p>@ Degradation_of_branched-chain_amino_acids</p><p>@ Leucine_degradation</p><p>@ Leucine_deamination</p><p>* L-leucine_deamination_via_aminotransferases</p><p>. 2.6.1.6 - Leucine Aminotransferase sequence not known</p><p> or . 2.6.1.42 - Branched-chain Amino Acid Aminotransferase</p><p>BC1776, BA_2352 97% identical BC1396, BA_1936 98% identical</p><p>* L-leucine_oxidative_deamination_via_leucine_dehydrogenase</p><p>. 1.4.1.9 - Leucine Dehydrogenase</p><p>BC4162, BA_4842 99% identical</p><p>* 2-oxoisocaproate_degradation_via_branched-chain_alpha-keto_acid_dehydrogenase</p><p>. 1.2.4.4 - 2-oxoisovalerate Dehydrogenase beta subunit</p><p>BC4158, BA_4838 99% identical</p><p>. 1.2.4.4 - 2-oxoisovalerate Dehydrogenase alpha subunit</p><p>BC4159, BA_4839 97% identical</p><p>. Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex (EC 2.3.1.-)</p><p>BC4157, BA_4837 98% identical</p><p>. 1.8.1.4 - Dihydrolipoamide Dehydrogenase</p><p>BC4160, BA_4840 99% identical</p><p>* Isovalerate_fermentation</p><p>. 2.3.1.19 - Phosphate Butyryltransferase</p><p>BC4163, BA_4843 96% identical</p><p>. 2.7.2.14 - Branched-chain-fatty-acid Kinase</p><p>BC4161, BA_4841 97% identical</p><p>@ Valine_degradation</p><p>@ Valine_deamination</p><p>* L-valine_deamination_via_branched-chain-amino-acid_transaminase</p><p>. 2.6.1.42 - Branched-chain Amino Acid Aminotransferase</p><p>BC1776, BA_2352 97% identical</p><p>BC1396, BA_1936 98% identical</p><p>* L-valine_deamination_via_dehydrogenases</p><p>. 1.4.1.8 - Valine Dehydrogenase (nadp+) . 1.4.1.9 - Leucine Dehydrogenase</p><p>BC4162, BA_4842 99% identical</p><p>* Ketovaline--isobutyryl-CoA</p><p>. 1.2.4.4 - 2-oxoisovalerate Dehydrogenase beta subunit</p><p>BC4158, BA_4838 99% identical</p><p>. 1.2.4.4 - 2-oxoisovalerate Dehydrogenase alpha subunit</p><p>BC4159, BA_4839 97% identical</p><p>. Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex (EC 2.3.1.-)</p><p>BC4157, BA_4837 98% identical</p><p>. 1.8.1.4 - Dihydrolipoamide Dehydrogenase</p><p>BC4160, BA_4840 99% identical</p><p>* Isobutyrate_fermentation</p><p>. 2.3.1.19 - Phosphate Butyryltransferase</p><p>BC4163, BA_4843 96% identical</p><p>. 2.7.2.14 - Branched-chain-fatty-acid Kinase</p><p>BC4161, BA_4841 97% identical</p><p>@ Isoleucine_degradation</p><p>@ Isoleucine_deamination</p><p>* L-isoleucine_deamination_via_branched-chain-amino-acid_transaminase</p><p>. 2.6.1.42 - Branched-chain Amino Acid Aminotransferase</p><p>BC1776, BA_2352 97% identical</p><p>BC1396, BA_1936 98% identical</p><p>* L-isoleucine_oxidative_deamination_via_leucine_dehydrogenase</p><p>. 1.4.1.9 - Leucine Dehydrogenase</p><p>BC4162, BA_4842 99% identical</p><p>* 3-Methyl-2-oxopentanoate--2-methylbutyryl-CoA . 1.2.4.4 - 2-oxoisovalerate Dehydrogenase beta subunit</p><p>BC4158, BA_4838 99% identical</p><p>. 1.2.4.4 - 2-oxoisovalerate Dehydrogenase alpha subunit</p><p>BC4159, BA_4839 97% identical</p><p>. Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex (EC 2.3.1.-)</p><p>BC4157, BA_4837 98% identical</p><p>. 1.8.1.4 - Dihydrolipoamide Dehydrogenase</p><p>BC4160, BA_4840 99% identical</p><p>* 2-methylbutyrate_fermentation</p><p>. 2.3.1.19 - Phosphate Butyryltransferase</p><p>BC4163, BA_4843 96% identical</p><p>. 2.7.2.14 - Branched-chain-fatty-acid Kinase</p><p>BC4161, BA_4841 97% identical</p><p>@ Degradation_of_homocysteine,_homoserine_and_threonine</p><p>@ Threonine_degradation</p><p>* Threonine--glycine_degradation</p><p>. 1.1.1.103 - L-threonine 3-dehydrogenase</p><p>BC0622, BA_1204 97% identical</p><p>. 2.3.1.29 - Glycine C-acetyltransferase</p><p>BC0621, BA_1203 99% identical</p><p>* Threonine--2-oxobutanoate_degradation</p><p>. 4.2.1.16 - Threonine Dehydratase</p><p>BC2400, RBAT10057 82% identical</p><p>BC1781, BA_2357 96% identical</p><p>* Homocysteine--2-oxobutanoate_catabolism</p><p>. 4.4.1.1 - Cystathionine Gamma-lyase BC4366, BA_5041 98% identical</p><p>* Homoserine--2-oxobutanoate_catabolism</p><p>. 4.4.1.1 - Cystathionine Gamma-lyase</p><p>BC4366, BA_5041 98% identical</p><p>* 2-oxobutanoate_decarboxylation_by_pyruvate_dehydrogenase_complex</p><p>. 1.2.4.1 - Pyruvate Dehydrogenase E1 Component alpha subunit</p><p>BC3973, BA_4650 98% identical</p><p>. 1.2.4.1 - Pyruvate Dehydrogenase E1 Component beta subunit</p><p>BC3972, BA_4649 99% identical</p><p>. 2.3.1.12 - Dihydrolipoamide Acetyltransferase Component of pyruvate dehydrogenase complex</p><p>BC3971, BA_4648 98% identical</p><p>. 1.8.1.4 - Dihydrolipoamide dehydrogenase</p><p>BC3970, BA_4647 99% identical</p><p>@ Degradation_of_glycine_and_sarcosine</p><p>* Sarcosine_degradation_by_glycine_oxidase</p><p>. Glycine oxidase (ec 1.5.3.-)</p><p>BC0747, BA_1318 93% identical</p><p>@ Glycine_degradation</p><p>* Glycine_decarboxylase_complex</p><p>. 1.4.4.2 - Glycine Dehydrogenase (decarboxylating)</p><p>BC4225, BA_4902 99% identical</p><p>BC4224, BA_4901 97% identical</p><p>. 2.1.2.10 - Aminomethyltransferase</p><p>BC4226, BA_4903 100% identical</p><p>* Glycine_oxidase</p><p>BC0747, BA_1318 93% identical @ Degradation_of_histidine,_aspartate_and_asparagine</p><p>@ Histidine_degradation</p><p>@ Histidine--glutamate_degradation </p><p>* Histidine--glutamate,_formamide_catabolism</p><p>. 4.3.1.3 - Histidine Ammonia-lyase</p><p>BC3652, BA_4195 97% identical</p><p>. 4.2.1.49 - Urocanate Hydratase</p><p>BC3651, BA_4194 99% identical</p><p>. 3.5.2.7 - Imidazolonepropionase</p><p>BC3650, BA_4193 99% identical</p><p>. 3.5.3.8 - Formiminoglutamase</p><p>BC3649, BA_4192 97% identical</p><p>* Formamidase</p><p>. 3.5.1.49 - Formamidase sequence not known</p><p>@ Asparagine_degradation</p><p>* Asparaginase</p><p>. 3.5.1.1 - Asparaginase</p><p>BC3094, BA_3638 98% identical</p><p>BC1496, BA_2038 95% identical</p><p>@ Aspartate_degradation</p><p>* L-aspartate--D-aspartate_anabolism</p><p>. 5.1.1.13 - Aspartate Racemase</p><p>BC4750, BA_5425 90% identical</p><p>BC2177, BA_2726 87% identical</p><p>BC2623, BA_3158 94% identical</p><p>@ D-aspartate_degradation</p><p>* D-aspartate_deamination_via_D-alanine_aminotransferase . 2.6.1.21 - D-alanine Aminotransferase</p><p>BC2209, BA_2758 91% identical</p><p>BC5233, BA_0320 73% identical</p><p>@ Bacterial_Nucleic_acid_metabolism</p><p>@ Bacterial_DNA_Repair</p><p>@ Bacterial_Excision_Repair</p><p>* Nucleotide_Excision_Repair_NER</p><p>. Excinuclease ABC subunit A</p><p>BC2513, RBAT10056 81% identical</p><p>BC5167, BA_0253 99% identical</p><p>. Excinuclease ABC subunit B</p><p>BC5168, BA_0254 99% identical</p><p>. Excinuclease ABC subunit C</p><p>BC4520, BA_5187 97% identical</p><p>. DNA helicase II (EC 3.6.1.-)</p><p>BC0340, BA_0876 98% identical</p><p>. DNA polymerase I (EC 2.7.7.7)</p><p>BC4587, BA_5255 98% identical</p><p>. 6.5.1.2 - Dna Ligase (nad+)</p><p>BC0341, BA_0877 98% identical</p><p>. 4.2.99.18 - Dna-(apurinic Or Apyrimidinic Site) Lyase</p><p>BC1548, BA_2089 94% identical</p><p>. Transcription-repair coupling factor</p><p>BC0058, BA_0641 98% identical</p><p>. DNA repair protein recN</p><p>BC4173, RBAT10024 98% identical . Uvr repair protein</p><p>BA_3794</p><p>BXB0094</p><p>. UvrC-like protein</p><p>BC2713, BA_3227 87% identical</p><p>BC3107, BA_3641 92% identical</p><p>. UV-ENDONUCLEASE (UvsE/Uve1/UvdE Family)</p><p>BC0260, BA_0818 92% identical</p><p>BC5347, BA_0449 90% identical</p><p>* Base_Excision_Repair_BER</p><p>. 2.1.1.63 - Methylated-dna--[protein]-cysteine S-methyltransferase</p><p>BC3741, BA_4345 89% identical</p><p>BC2024, BA_2538 87% identical</p><p>. Ada Regulatory Protein</p><p>BC3740, BA_4344 89% identical</p><p>. 3.2.2.21 - Dna-3-methyladenine Glycosylase Ii</p><p>BC3742, BA_4346 86% identical</p><p>BC0468, BA_1003 94% identical</p><p>. Uracil-DNA glycosylase (EC 3.2.2.-)</p><p>BC5398, BA_0505 93% identical</p><p>. Single-stranded-DNA-specific exonuclease recJ (EC 3.1.-.-)</p><p>BC4403, BA_5077 96% identical</p><p>. Mutator mutT protein (7,8-dihydro-8-oxoguanine-triphosphatase) (EC 3.6.1.-)</p><p>BC5157, BA_0243 100% identical</p><p>BC3037, BA_3568 90% identical</p><p>. 4.2.99.18 - Dna-(apurinic Or Apyrimidinic Site) Lyase</p><p>BC1548, BA_2089 94% identical . 3.2.2.23 - Dna-formamidopyrimidine Glycosylase</p><p>BC4586, BA_5254 98% identical</p><p>. A/G-specific adenine DNA glycosylase (EC 3.2.2.-)</p><p>BC0504, BA_1092 95% identical</p><p>. 3.1.11.2 - Exodeoxyribonuclease Iii</p><p>BC0415, BA_0947 90% identical</p><p>BC3739, BA_4343 94% identical</p><p>. 3.1.21.2 - Deoxyribonuclease Iv (phage T4-induced)</p><p>BC4282, BA_4956 98% identical</p><p>. 6.5.1.2 - Dna Ligase (nad+)</p><p>BC0341, BA_0877 98% identical</p><p>@ Mismatch_Repair</p><p>* Long-Patch_MMR</p><p>. DNA mismatch repair protein mutL</p><p>BC3768, BA_4374 96% identical</p><p>. DNA mismatch repair protein mutS</p><p>BC3769, BA_4375 97% identical</p><p>BC3480, BA_4039 96% identical</p><p>BC4552, BA_5220 98% identical</p><p>. Mutator mutT protein (7,8-dihydro-8-oxoguanine-triphosphatase) (EC 3.6.1.-)</p><p>BC5157, BA_0243 100% identical</p><p>BC3037, BA_3568 90% identical</p><p>BC0540, BA_1114 94% identical</p><p>. MutT/nudix family protein</p><p>BC4636, BA_5308 81% identical</p><p>BC2686, BA_3192 83% identical</p><p>. A/G-specific adenine DNA glycosylase (EC 3.2.2.-) BC0504, BA_1092 95% identical</p><p>. Single-stranded-DNA-specific exonuclease recJ (EC 3.1.-.-)</p><p>BC4403, BA_5077 96% identical</p><p>. 3.1.11.6 - Exodeoxyribonuclease Vii</p><p>BC4179, BA_4856 98% identical</p><p>. DNA polymerase III alpha subunit (EC 2.7.7.7)</p><p>BC3816, BA_4426 98% identical</p><p>BC4605, BA_5272 96% identical</p><p>BC3611, BA_4159 92% identical</p><p>. DNA polymerase III, epsilon chain (EC 2.7.7.7)</p><p>BC3538, BA_4085 87% identical</p><p>. DNA polymerase III, beta chain (EC 2.7.7.7)</p><p>BC2693, BA_3202 86% identical</p><p>BC0002, BA_0597 96% identical</p><p>. DNA polymerase III, delta subunit (EC 2.7.7.7)</p><p>BC4321, BA_4995 97% identical</p><p>. DNA polymerase III, delta' subunit (EC 2.7.7.7)</p><p>BC0037, BA_0619 96% identical</p><p>. DNA polymerase III subunit gamma/tau (EC 2.7.7.7)</p><p>BC0024, BA_0613 96% identical</p><p>. Single-strand DNA binding protein</p><p>BC5475, BA_0580 98% identical</p><p>BC2154, BA_2661 91% identical</p><p>* Short-Patch_MMR</p><p>. DNA mismatch repair protein mutS</p><p>BC3769, BA_4375 97% identical</p><p>BC3480, BA_4039 96% identical BC4552, BA_5220 98% identical</p><p>. DNA mismatch repair protein mutL</p><p>BC3768, BA_4374 96% identical</p><p>. DNA polymerase I (EC 2.7.7.7)</p><p>BC4587, BA_5255 98% identical</p><p>* Recombinational_Repair_RER</p><p>. 3.1.11.5 - Exodeoxyribonuclease V</p><p>BC4389, BA_5063 98% identical</p><p>. ATP-dependent nuclease subunit A</p><p>BC1138, BA_1689 97% identical</p><p>. ATP-dependent nuclease subunit B</p><p>BC1137, BA_1688 96% identical</p><p>. Single-stranded-DNA-specific exonuclease recJ (EC 3.1.-.-)</p><p>BC4403, BA_5077 96% identical</p><p>. ATP-dependent DNA helicase recQ (EC 3.6.1.-)</p><p>BC2815, BA_3339 97% identical</p><p>BC1485, BA_2026 94% identical</p><p>. ATP-dependent DNA helicase recG (EC 3.6.1.-)</p><p>BC3853, BA_4464 98% identical</p><p>. Regulatory protein recX</p><p>BC0498, BA_1086 95% identical</p><p>. Recf Protein</p><p>BC0004, BA_0599 98% identical</p><p>. DNA repair protein recO</p><p>BC4295, BA_4969 98% identical</p><p>. Recombination protein recR</p><p>BC0026, BA_0615 99% identical . Holliday junction DNA helicase ruvA</p><p>BC4415, BA_5089 99% identical</p><p>. Holliday junction DNA helicase ruvB</p><p>BC4414, BA_5088 97% identical</p><p>. DNA repair protein recN</p><p>BC4173, RBAT10024 98% identical</p><p>. DNA polymerase I (EC 2.7.7.7)</p><p>BC4587, BA_5255 98% identical</p><p>. DNA repair protein radC</p><p>BC4461, BA_5125 87% identical</p><p>. DNA repair protein RadA</p><p>BC0103, BA_0671 99% identical</p><p>. Recombination protein recU</p><p>BC1554, BA_2092 96% identical</p><p>. Primosomal protein N'</p><p>BC3866, BA_4477 96% identical</p><p>. Primosomal protein dnaI</p><p>BC4579, BA_5247 98% identical</p><p>. Replicative DNA helicase (EC 3.6.1.-)</p><p>BC0956, BA_1513 96% identical</p><p>BC5470, BA_0575 97% identical</p><p>. DNA primase (EC 2.7.7.-)</p><p>BC4290, BA_4965 88% identical</p><p>* SOS_Error-Prone_Repair_SOS</p><p>. Regulatory protein recX</p><p>BC0498, BA_1086 95% identical</p><p>. 3.4.21.88 - Repressor Lexa BC3690, BA_4235 100% identical</p><p>. ATP-dependent helicase, DinG family</p><p>BC1543, BA_2084 91% identical</p><p>BC1565, BA_2103 98% identical</p><p>. Excinuclease ABC subunit A</p><p>BC2513, RBAT10056 81% identical</p><p>BC5167, BA_0253 99% identical</p><p>. Excinuclease ABC subunit B</p><p>BC5168, BA_0254 99% identical</p><p>. DNA polymerase IV (EC 2.7.7.7)</p><p>BC4142, BA_4822 95% identical</p><p>. Recombination protein recR</p><p>BC0026, BA_0615 99% identical</p><p>. Holliday junction DNA helicase ruvA</p><p>BC4415, BA_5089 99% identical</p><p>. Holliday junction DNA helicase ruvB</p><p>BC4414, BA_5088 97% identical</p><p>. ATP-dependent DNA helicase recG (EC 3.6.1.-)</p><p>BC3853, BA_4464 98% identical</p><p>. Cell division inhibitor</p><p>BC0497, BA_1085 90% identical</p><p>. Cell division protein ftsZ</p><p>BC3906, BA_4515 81% identical</p><p>. DinB protein</p><p>BC2315, BA_2874 90% identical</p><p>@ Bacterial_Direct_Damage_Reversal</p><p>* Bacterial_specialized_photorepair . Spore photoproduct lyase (EC 4.1.99.-)</p><p>BC4205, BA_4882 97% identical</p><p>* Bacterial_photorepair</p><p>. 4.1.99.3 - Deoxyribodipyrimidine Photolyase</p><p>BC3137, BA_3689 90% identical</p><p>* Bacterial_DNA-joining</p><p>. 6.5.1.2 - Dna Ligase (nad+)</p><p>BC0341, BA_0877 98% identical</p><p>* Bacterial_alkylation-damage_repair</p><p>. Ada Regulatory Protein</p><p>BC3740, BA_4344 89% identical</p><p>. 2.1.1.63 - Methylated-dna--[protein]-cysteine S-methyltransferase</p><p>BC3741, BA_4345 89% identical</p><p>BC2024, BA_2538 87% identical</p><p>@ Bacterial_Restriction_Modification</p><p>* Restriction_Modification_Type_Mmr</p><p>. 5-methylcytosine-specific restriction enzyme MRR (EC 3.1.21.-)</p><p>RBAT10021</p><p>* Restriction_Modification_Type_Mcr</p><p>. 5-methylcytosine-specific restriction enzyme A (EC 3.1.21.-)</p><p>BC2144</p><p>BC2145</p><p>. 5-methylcytosine-specific Restriction Related Enzyme</p><p>BC2236, BA_2788 88% identical</p><p>* Restriction_Modification_Type_I</p><p>. Type I Restriction-modification System Specificity Subunit</p><p>BC4458 BC4460</p><p>. Type I Restriction-modification System Methylation Subunit</p><p>BC4459</p><p>. Type I Restriction-modification System Restriction Subunit (ec 3.1.21.3)</p><p>BC4456</p><p>BC4457</p><p>* Restriction_Modification_TypeII</p><p>. Type Ii Restriction-modification System Restriction Subunit (ec 3.1.24.1)</p><p>BC0939</p><p>BC0940</p><p>. Type Ii Restriction-modification System Methylation Subunit</p><p>BC0941</p><p>Pathways from the Integrated Genomics proprietary pathway collection are organized into the functional hierarchy. Only those parts of the functional hierarchy that are discussed in the paper are presented in the table. For Ban CDSs that were not identified by GenBank, Integrated Genomics CDS numbers are used; sequences of these CDSs along with annotations and partial reconstructions of Bce and Ban can be found at http://www.ergo-light.com. CDSs in the table are pairs of close bi-directional best hits from Bce and Ban that are listed according to their functional assignment, which corresponds to the functional role in the pathway. Percent of identity is that of protein sequences.</p>
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