<p>Additional file 2: Table S2 Ex vivo secreted cytokines</p><p>All A A A B B B C t B 1 t L 2 1 BL t24 BL 2 BL sett BL BL t24 Cytokine ST m BL STD m mea me m me ing mean STD mean D e e n an e an a a a n n n</p><p>IFNα me diu 1 3 2 5 1 8 0 1 0 2 0 (pg/ml) m PM IFNα A/i 1 ono 16 15 10 10 12 16 12 14 18 17 (pg/ml) my 3 cin 2 TNFα me 6 37 392 diu 2122 2560 2938 3192 2881 3457 7443 1471 (pg/ml) m 8 85 6 6 4 TNFα LP 1 56 758 4435 3874 4107 4761 6081 4924 11039 3970 (pg/ml) S 6 94 1 8 PM 3 TNFα A/i 24 41. ono 36.4 23.5 3. 26.3 36.3 44.8 22.2 48.2 33.3 (ng/ml) .4 2 my 6 cin me IFNγ diu 13 12 9 5 10 12 20 19 13 42 7 (U/ml) m IFNγ LP 1 25 32 7 13 28 40 38 31 76 10 (U/ml) S 3 PM A/i 9 IFNγ(U/ 83 ono 961 319 2 264 906 1052 178 899 1049 932 ml) 1 my 6 cin 2 IL-4 me 30 diu 552 813 8 305 194 448 551 563 665 1030 (pg/ml) 8 m 0 PM 1 IL-4 A/i 1 96 109 ono 124.5 73.2 53.0 106.8 133.1 66.7 135.9 119.4 (ng/ml) my 1. .2 .5 cin 7 5 IL-10 me 41 diu 466 297 5 386 521 459 303 426 415 435 (pg/ml) 1 m 2 IL-10 LP 1053 679 1 935 80 1078 1067 640 955 1069 959 (pg/ml) S 1 8 2 8 PM 3 IL-10 A/i 33 35. ono 33.8 30.2 2. 26.7 59.5 55.2 43.3 103.3 22.8 (ng/ml) .8 4 my 0 cin 2 IL-17 me 24 diu 154 224 4 314 196 240 252 180 212 53 (U/ml) 3 m 8 PM IL-17 2 A/i 22 23. (1000 ono 27.8 14.0 5. 13.7 24.2 29.7 13.5 30.2 27.4 .3 0 U/ml) my 6 cin Equine cytokines in PBMC supernatants after 12 h of cell culture: mean concentration (STD); BL: Baseline (mean t-24 – t0); t12: 12 h post-treatment; t24: 24 h post-treatment; Detection limits: IFNα (12 – 30,000 pg/ml), TNFα (31.2 – 2,000 pg/ml), IFNγ (10 – 5,000 U/ml), IL-4 (40 – 80,000 pg/ml), IL-10 (15 – 35,000 pg/ml), and IL-17 (10 – 10,000 U/ml).</p>