The Institutional Animal Care and Use Committee (Iacuc) s1

The Institutional Animal Care and Use Committee (Iacuc) s1

<p> THE INSTITUTIONAL ANIMAL CARE AND USE COMMITTEE (IACUC) </p><p>IACUC / LARC STANDARD PROCEDURES</p><p>Title of Standard Procedure:</p><p>Body Condition Scoring of Rats</p><p>Description of procedure:</p><p>Scoring the body condition of rodents is a non- invasive method for assessing health and establishing endpoints for adults where body weight is not a viable monitoring tool, such as with tumor models, ascites production and pregnancy, or young growing animals. Body condition scores (BCS) range from 1 (emaciation) to 5 (obesity). An anticipated BCS of 2 (underconditioned) or lower requires justification in the protocol. Scores are determined by frequent visual and hands-on examination of each animal. For the hands-on evaluation, allow the rat to rest on the cage’s wire top. Assess the vertebrae by palpation of the lumbar spine and the pelvic bones by palpation of the hips. Match the findings to the descriptions and diagrams provided to determine a score. Scores must be documented for each animal.</p><p>Literature search words required:</p><p>Literature search was performed for refinement of this Standard Procedure in June 2010:</p><p>Key Words Search Site Years Covered Body condition Pubmed and Full scoring BIOSIS database Rats/Rodents Previews up to 2010</p><p>One reference found for rats.</p><p>Reference used:</p><p>Hickman, D.L., M. Swan. 2010. Use of a body condition score technique to assess health status in a rat model of polycystic kidney disease. J Am Assoc Lab Anim Sci. 49(2):155-9.</p><p>Updated 8/2010</p>

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