<p>Appendix II. Row numbers of occurrences of the 20 aminoacids at several positions considered in this work in the sequences given in the alignment of Appendix I with similarity with the query higher than 0.25. Bold numbers indicate the residue present in WT E. coli thioredoxin.</p><p>RES. G A V L I S T C M P D N E Q K R H F Y W POS. 4 - - 122 13 85 1 2 - 8 3 - 1 1 - - - - - 4 - 5 - 5 87 70 85 - 11 - 3 1 - - 1 3 20 2 2 11 1 - 16 - 34 209 55 59 1 35 - 6 1 - - 2 1 4 - - 11 2 - 23 - 20 250 32 59 7 17 2 11 - - - - - 1 1 - 1 - 44 25 - 15 333 29 61 2 3 4 1 - - - - - 1 - - 19 1 - 38 2 5 24 175 144 - 5 - 57 - 1 - 4 18 - - 2 50 3 - 41 - 29 90 24 135 9 41 1 8 - 9 1 77 6 13 9 4 19 4 4 45 - 86 68 197 73 3 4 2 24 - 1 ------19 5 4 55 - 10 103 130 91 - 4 5 3 - - - 2 0 1 0 2 119 4 5 60 4 72 154 9 73 8 46 69 4 - 5 1 0 0 3 11 5 4 1 0 72 - 5 226 18 237 ------1 ------75 - 1 35 39 181 - 37 - 49 - - - 1 2 1 - - 55 85 1 86 4 27 99 46 32 4 10 - 19 39 3 2 45 28 47 8 - 5 2 - 91 4 29 148 14 36 32 13 1 11 14 11 17 13 19 7 6 9 4 3 -</p>