<p>EP 16 Cancer Center Interdisciplinary Collaboration across multiple settings</p><p>From: Smith, Christine Date: Wednesday, August 31, 2911 5:29 PM To: [email protected]; Donington, Jessica Cc: Williams, Pamela; DeVolk, April; Harr, Jodi; Lowen, Shelley; Tucker, Kelinda; Winemiller, Cynthia; Zach, Leigh Subject: RTOG-839</p><p>I have a patient on the RTOG 0839 study. He has completed his induction treatment, but we have delayed surgery now for 7 weeks and it appears to be delayed at minimum another week, due to AQFRB infection in the lung. My questions is do I need to pull patient off study due to the delay? Christine Smith RN OCN Clinical Research Coordinator, Penrose Cancer Center Research Department ------</p><p>From: Donington, Jessica Date: Wednesday, August 31, 2911 5:29 PM To: Smith, Christine; [email protected]; Cc: Williams, Pamela; DeVolk, April; Harr, Jodi; Lowen, Shelley; Tucker, Kelinda; Winemiller, Cynthia; Zach, Leigh Subject: RTOG-839</p><p>Christine, This is not a major deviation from a surgical standpoint as of now, but an active AFB infection is not something that can be quickly resolved. Can you send me the date for when the patient finished therapy and the projected date for resection? What criteria are being used to determine timing for surgery?</p><p>Jessica S. Donington, MD, Assistant Professor Cardiothoracic Surgery, NYU School of Medicine ------From: Martin Edelman Date: Tuesday, September 06, 2011 5:39 AM To: Smith, Christine; Jessica Donington Cc: Williams, Pamela; DeVolk, April; Harr, Jodi; Lowen, Shelley; Tucker, Kelinda; Winemiller, Cynthia; Zach, Leigh Subject: RTOG-839</p><p>If the patient does not proceed to surgery, then he could be considered for the “consolidation” portion of chemotherapy. That, of course, assumes that the infection has resolved and the patient has adequate PS etc. If the patient is not felt suitable for further treatment, the reasons must be documented. As patients are followed for the secondary endpoints, they are never truly “off study”. Martin J Edelman, MD, Professor of Medicine, University of Maryland School of Medicine</p>