<p> KnO2wledge Kathmandu: Oxygen The 10th anniversary Caudwell Xtreme Everest Meeting in Kathmandu</p><p>Yak and Yeti Hotel, Tuesday March 28th and 29th 2017 Organised by the Xtreme Everest Oxygen Research Consortium in collaboration with the Nepal Mountain Medicine Society</p><p>Chairs: Prof Mike Grocott and Sr Kay Mitchell</p><p>09.30-11.00 SESSION 1: INTRODUCTION Mike Grocott 09.30-09.40 Welcome and introduction Mike Grocott 09.40-10.10 Xtreme Everest: the journey Kay Mitchell 10.10-10.40 History of altitude research George Rodway 10.40-11.10 Cardiopulmonary physiology Sue Ward 11.10-11.30 COFFEE 11.30-13.00 SESSION 2: PHYSIOLOGY AT ALTITUDE Kay Mitchell 11.30-12.00 Oxygen delivery and consumption Denny Levett 12.00-12.30 Microcirculatory blood flow at altitude Daniel Martin 12.30-13.00 Metabolism at altitude Andrew Murray 12.30-13.30 LUNCH 13.30-15.00 HIGH ALTITUDE ILLNESS AND DYSFUNCTION Dan Martin 13.00-14.00 Illness at altitude Denny Levett 14.00-14.30 The Airways at Altitude David Howard 14.30-15.00 The Brain at Altitude Mike Grocott 15.00-15.30 COFFEE 15.30-16.30 Denny Levett 15.30-15.45 Translation into practice Kay Mitchell 15.45-16.25 Climbing to the summit Dan Martin 16.25-16.30 Closing remarks Mike Grocott and Kay Mitchell UK-Nepal Medical Congress The 10th anniversary Caudwell Xtreme Everest Meeting in Kathmandu</p><p>Yak and Yeti Hotel, Wednesday March 29th 2017 Organised by the Xtreme Everest Oxygen Research Consortium in collaboration with the Nepal Mountain Medicine Society</p><p>Chairs: Prof Buddha Basnyat and Prof Mike Grocott</p><p>09.30-11.00 SESSION 1: OXYGEN DELIVERY? Buddha Basnyat 09.30-09.40 Welcome and introduction Buddha Basnyat 09.40-10.10 Exercise is medicine? Denny Levett 10.10-10.40 Fluid Therapy Monty Mythen 10.40-11.10 Oxygen therapy Daniel Martin 11.10-11.30 COFFEE 11.30-13.00 SESSION 2: INFECTION Monty Mythen 11.30-12.00 Infectious diseases in Nepal Buddha Basnyat 12.00-12.30 What is the microbiome? Mike Grocott 12.30-13.00 Patan hospital ID RCT azithromycin vs cotrimoxazole with Oxford University. 12.30-13.30 LUNCH 13.30-15.00 MOUNTAIN ILLNESS Buddha Basnyat 13.00-14.00 Mountain Medicine Society does ( from volunteering as doctors at the Everest Base Camp to working with Nick Mason's group ( IPPG) at Machermo to helping out at the Gosainkunda ( pilgrimage) festival etc. </p><p>14.00-14.30 There will also be a presentation of a completed ( and about to be published) randomization double blind study about paracetamol vs ibuprofen in the prevention of AMS at 4300 m at Pheriche and 14.30-15.00 young docs will also present case reports of interesting altitude material we have seen. We may also have a study about the impact of new Himalayan roads on AMS, time permitting 15.00-15.30 COFFEE 15.30-14.30 ADVENTURES IN MEDICINE AND SURGERY Kay Mitchell 15.30-16.00 Adventures in critical care Max Jonas 16.00-16.30 Adventures in the upper airway David Howard 16.30 Closing remarks Buddha Basnyat and Mike Grocott </p>