<p> S8 Table: List of functionally annotated domain of 578 proteins with known function from Mycobacterium tuberculosis </p><p>S. No. PROTEIN NAME Gene ID Function</p><p>1. HP Rv0004 NP_214518.1 RNA Binding protein 2. HP Rv0021C NP_214535.1 Oxidoreductage 3. HP Rv 0025 NP_214539.1 Biofilm regulator 4. HP Rv0026 NP_214540.1 Biofilm regulator NP_214541.1 ESX-1 secretion-associated 5. HP Rv0027 | protein</p><p>6. HP RvOO28 NP_214542.1 DUF2694 domain containing protein 7. HP Rv0030 NP_214544.1 Transposase 8. HP Rv0034 NP_214548.1 ACP 9. HP Rv0036 NP_214550.1 Mycothiolmaleylpyruvateisomerase N- terminal domain 10. HP Rv0038 NP_214552.1 transcriptional regulator 11. HP Rv0040 NP_214554.2 proline-rich antigen 12. HP Rv0047 NP_214561.1 PadR family transcriptional regulator 13. HP Rv0052 NP_214566.3 DJ-1/PfpI family protein 14. HP Rv0060 NP_214574.1 RNase III inhibitor 15. HP Rv0074 NP_214588.1 imidazolonepropionase 16. HP Rv0079 NP_214593.1 putative regulatory protein 17. HP Rv0080 NP_214594.1 Pyridoxamine 5'-phosphate oxidase 18. HP Rv0094C NP_214608.1 repeat protein 19. HP Rv0095C NP_214609.1 REP13E12 repeat protein 20. HP Rv 0104 NP_214618.1 S-adenosyl-L-homocysteine hydrolase 21. HP Rv 0106 NP_214620.1 Probable cobalamin synthesis protein 22. HP Rv0138 NP_214652.1 polyketidecyclase 23. HP Rv0140 NP_214654.1 acyl-CoA thioesterase 24. HP Rv0141c NP_214655.1 Ketosteroidisomerase-related protein HP Rv 0121c NP_214635.1 PPOX class F420-dependen 25. | oxidoreductase</p><p>26. HP Rv 0163 NP_214677.1 4-hydroxybenzoyl-CoA thioesterase 27. HP Rv 0184 NP_214698.1 DUF2786 domain-containing protein 28. HP Rv 0190 NP_214704.1 CopY family transcriptional regulator 29. HP Rv 0192 NP_214706.1 Transpeptidase 30. HP Rv 0203 NP_214717.1 Hemophore 31. HP Rv 0207C NP_214721.1 NYN domain protein 32. HP Rv 0225 NP_214739.1 glycosyltransferase 33. HP Rv 0229C NP_214743.2 twitching motility protein PilT 34. HP Rv0259C NP_214773.1 sirohydrochlorincobaltochelatase 35. HP Rv0263C NP_214777.1 allophanate hydrolase 36. HP Rv0264C NP_214778.1 allophanate hydrolase 37. HP Rv0268C NP_214782.1 prevent-host-death protein 38. HP Rv0274 NP_214788.1 glyoxalase/bleomycin resistance protein/dioxygenase 39. HP Rv0276 NP_214790.1 FadD2 7</p><p>40. HP Rv0293c NP_214807.1 alpha/beta hydrolase family protein 41. HP Rv0295c NP_214809.1 sulfotransferase 42. HP Rv0310c NP_214824.1 bile acid 7-alpha dehydratase 43. HP Rv0312 NP_214826.1 putative proline and threonine rich protein 44. HP Rv0323c NP_214837.1 Mycothiol conjugate amidaseMca 45. HP Rv0326 NP_214840.1 6-O-methylguanine DNA methyltransferase 46. HP Rv0329 NP_214843.1 Methyltransferase domain 47. HP Rv0330c NP_214844.1 TetR family transcriptional regulator 48. HP Rv0333 NP_214847.1 SnoaL-like domain protein 49. HP Rv0336 NP_214850.1 13E12 repeat family protein 50. HP Rv0345 NP_214859.1 MobA-like protein 51. HP Rv0356c NP_214870.1 thioesterase superfamily protein 52. HP Rv0365c NP_214879.1 fructose-bisphosphatealdolase 53. HP Rv0366c NP_214880.1 ATPase 54. HP Rv0367c NP_214881.1 ParD-like antitoxin of type II bacterial toxin- antitoxin system 55. HP Rv0368c NP_214882.1 VWA containing CoxE family protein 56. HP Rv0371 NP_214885.1 carbon monoxide dehydrogenase 57. HP Rv0372c NP_214886.1 xanthine dehydrogenase accessory factor 58. HP Rv0376c NP_214890.1 xanthine dehydrogenase accessory factor 59. HP Rv0390 NP_214904.1 sulfurtransferase 60. HP Rv0393 NP_214907.1 13E12 repeat family protein 61. HP Rv0430 NP_214944.1 Fis family transcriptional regulator 62. HP Rv0434 NP_214948.1 ATP-dependent protease 63. HP Rv0443 NP_214957.1 Chorismate synthase 64. HP Rv0448C NP_214962.1 DUF1365 domain-containing protein 65. HP Rv0449C NP_214963.1 Amine oxidase 66. HP Rv0455C NP_214969.1 DUF5078 domain-containing protein 67. HP Rv0459 NP_214973.1 UDP-glucose 4-epimerase 68. HP Rv0460 NP_214974.1 Putative membrane protein 69. HP Rv0464C NP_214978.1 4-carboxymuconolactone decarboxylase 70. HP Rv0466 NP_214980.1 acyl-ACP thioesterase 71. HP Rv0477 NP_214991.1 PF10783 family protein 72. HP Rv0481C NP_214995.1 carbon-nitrogen hydrolase 73. HP Rv0487 NP_215001.1 Mannosyltransferase 74. HP Rv0496 NP_215010.3 exopolyphosphatase 75. HP Rv0498 NP_215012.1 sugar phosphate isomerase/epimerase 76. HP Rv0499 NP_215013.1 diacylglycerol kinase catalytic subunit 77. HP Rv0502 NP_215016.1 acyltransferase 78. HP Rv0504C NP_215018.1 MaoC-like dehydratase 79. HP Rv0508 NP_215022.1 thioredoxin family protein 80. HP Rv0515 NP_215029.1 13E12 repeat family protein 81. HP Rv0518 NP_215032.1 lysophospholipase L1-like esterase 82. HP Rv0525 NP_215039.1 phosphoglyceratemutase 83. HP Rv0530 NP_215044.1 ATPase 84. HP Rv0540 NP_215054.1 glycosyltransferase involved in cell wall biogenesis 85. HP Rv0543C NP_215057.1 DUF3349 domain-containing protein 86. HP Rv0546C NP_215060.1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 87. HP Rv0552 NP_215066.1 amidohydrolase 88. HP Rv0559C NP_215073.1 putative secreted protein 89. HP Rv0566C NP_215080.1 YajQ family cyclic di-GMP-binding protein 90. HP Rv0569 NP_215083.1 cytochrome P450 91. HP Rv0571C NP_215085.1 phosphoribosyltransferase 92. HP Rv0574C NP_215088.1 poly-gamma-glutamate synthesis protein 93. HP Rv0577 NP_215091.1 transcriptional regulator 94. HP Rv0579 NP_215093.1 ub domain fused to Mut7-C family protein 95. HP Rv0587 NP_215101.1 ABC transporter permease 96. HP Rv0588 NP_215102.1 ABC transporter permease 97. HP Rv0597C NP_215111.1 ATPase AAA+ superfamily protein 98. HP Rv611C NP_215125.2 DUF4926 domain-containing protein 99. HP Rv613C NP_215125.2 tetratricopeptide repeat family protein 100. HP Rv 628c NP_215142.1 FIST C domain protein 101. HP Rv 647c NP_215161.1 protein kinase 102. HP Rv 674 NP_215188.1 PaaX domain-containing protein, C- domain protein 103. HP Rv 679c NP_215193.1 threonine rich protein 104. HP Rv 690c NP_215204.1 DUF2332 domain-containing protein 105. HP Rv 712 NP_215226.1 sulfatase-modifying factor 1 106. HP Rv 725c NP_215239.1 SAM-dependent methyltransferase 107. HP Rv 738 NP_215252.1 Mycothiolmaleylpyruvateisomerase N- terminal domain 108. HP Rv 739 NP_215253.1 Biofilm regulator%2C BssS 109. HP Rv 759c NP_215273.3 hit-like protein 110. HP Rv 760c NP_215274.3 steroid Delta-isomerase 111. HP Rv 774c NP_215288.2 Esterase 112. HP Rv 775 NP_215289.1 TetR family transcriptional regulator 113. HP Rv 776c NP_215290.1 RelA/SpoT domain-containing protein 114. HP Rv 784 NP_215298.1 putative deacetylase 115. HP Rv 786c NP_215300.2 MBL fold metallo-hydrolase 116. HP Rv 790c NP_215305.1 transglutaminase-like enzyme 117. HP Rv 791c NP_215306.1 Oxidoreductase 118. HP Rv 798c NP_215313.1 bacteriocin 119. HP Rv 799c NP_215314.1 Peroxidase 120. HP Rv 804 NP_215319.1 abortive phage infection protein 121. HP Rv 810c NP_215325.1 DUF3073 domain-containing protein 122. HP Rv 811c NP_215326.1 glycine cleavage system protein T 123. HP Rv 813c NP_215328.1 FABP family protein 124. HP Rv 814c NP_215329.1 thiosulfate sulfurtransferase cysA2 125. HP Rv 817c NP_215332.1 Protein of unknown function (DUF2993) 126. HP Rv 822c NP_215337.1 LytR family transcriptional regulator 127. HP Rv 825c NP_215340.1 TetR family transcriptional regulator 128. HP Rv 839 NP_215354.1 UbiE/COQ5 family methlytransferase 129. HP Rv 854 NP_215369.1 cyclase 130. HP Rv 856 NP_215371.1 cyclase 131. HP Rv 857 NP_215372.2 cyclase/dehydrase 132. HP Rv 862c NP_215377.1 DNA-binding protein 133. HP Rv 874c NP_215389.1 FIST N domain protein 134. HP Rv 875c NP_215390.1 DUF2771 domain-containing protein 135. HP Rv 883c NP_215398.1 DNA-binding protein 136. HP Rv0885 NP_215400.1 membrane protein 137. HP Rv0887C NP_215402.1 Glyoxalase 138. HP Rv0891c NP_215406.1 adenylate/guanylatecyclase domain- containing protein 139. HP Rv0898C NP_215413.1 DUF2630 domain-containing protein 140. HP RvO907 NP_215422.1 serine hydrolase 141. HP Rv0911 NP_215426.1 Hydroxylase 142. HP Rv0923C NP_215438.1 replication protein 143. HP Rv0925C NP_215440.1 flavodoxin 144. HP Rv0941C NP_215456.1 anti-anti-sigma factor 145. HP Rv0950C NP_215465.1 Phage peptidoglycan binding endopeptidase 146. HP Rv0966C NP_215481.2 DUF1707 domain-containing protein 147. HP Rv0968 NP_215483.1 DUF1490 domain-containing protein 148. HP Rv0976C NP_215491.1 exopolyphosphatase 149. HP Rv0988 NP_215503.1 exported protein 150. HP Rv0990C NP_215505.1 flagellar biosynthesis protein FlgA 151. HP Rv0991C NP_215506.1 FmdB family transcriptional regulator 152. HP Rv0992C NP_215507.1 5-formyltetrahydrofolate cyclo-ligase 153. HP Rv1025 NP_215541.1 septum formation initiator subfamily protein 154. HP Rv1026 NP_215542.1 exopolyphosphatase 155. HP Rv1043C NP_215559.1 membrane-associated serine protease 156. HP Rv1045 NP_215561.1 putative DUF1814 family protein 157. HP Rv1051C NP_215567.1 Helix-turn-helix domain 158. HP Rv1056 NP_215572.1 PF04248 domain protein 159. HP Rv1057 NP_215573.1 YVTN family beta-propeller repeat protein 160. HP Rv1059 NP_215575.1 dihydrodipicolinatereductas 161. HP Rv1060 NP_215576.1 Putative polyketidecyclase 162. HP Rv 1061 NP_215577.1 glutamine amidotransferase 163. HP Rv 1062 NP_215578.1 Patatin 164. HP Rv 1065 NP_215581.1 cysteine dioxygenase type I superfamily protein 165. HP Rv 1066 NP_215582.1 sulfurtransferase 166. HP Rv 1069C NP_215585.1 membrane protein 167. HP Rv 1075C NP_215591.1 exported protein 168. HP Rv 1078 NP_215594.1 Proline-rich antigen homolog 169. HP Rv 1084 NP_215600.1 transmembrane protein 170. HP Rv 1100 NP_215616.1 DUF4245 domain-containing protein 171. HP Rv 1101C NP_215617.1 AI-2E family transporter 172. HP Rv 1117 NP_215633.1 antibiotic biosynthesis monooxygenase 173. HP Rv 1120C NP_215636.1 adenylate/guanylatecyclase domain- containing protein 174. HP Rv 1125 NP_215641.1 DUF1298 domain-containing protein 175. HP Rv 1132 NP_215648.1 putative transmembrane protein 176. HP Rv 1147 NP_215663.1 phosphatidylethanolamine N- methyltransferase 177. HP Rv 1154C NP_215670.1 pyridoxamine 5'-phosphate oxidase 178. HP Rv 1156 NP_215672.1 Fe-S cluster assembly protein HesB 179. HP Rv 1176C NP_215692.1 PadR family transcriptional regulator 180. HP Rv 1179C NP_215695.1 DNA or RNA helicase of superfamily II 181. HP Rv 1184C NP_215700.1 PE-PPE domain-containing protein 182. HP Rv 1186C NP_215702.1 transcriptional regulator 183. HP Rv 1190 NP_215706.1 Hydrolase 184. HP Rv 1191 NP_215707.1 alpha/beta hydrolase 185. HP Rv 1194C NP_215710.1 transcriptional regulator 186. HP Rv 1205 NP_215721.1 Decarboxylase, TIGR00730 family Rossman fold protein 187. HP Rv 1211 NP_215727.1 DUF3117 domain-containing protein 188. HP Rv 1215C NP_215731.1 Hydrolase 189. HP Rv 1225C NP_215741.1 HAD superfamily hydrolase 190. HP Rv 1232C NP_215748.1 magnesium transporter 191. HP Rv 1233C NP_215749.1 membrane protein 192. HP Rv 1251C NP_215767.1 nuclease 193. HP Rv 1261C NP_215777.1 deazaflavin-dependent nitroreductase 194. HP Rv 1262C NP_215778.1 HIT family protein 195. HP Rv 1269C NP_215785.1 putative secreted protein 196. HP Rv 1271C NP_215787.1 secreted protein 197. HP Rv 1276C NP_215792.1 phosphohistidine phosphatase 198. HP Rv 1277 NP_215793.1 DNA repair exonuclease 199. HP Rv 1288 NP_215804.1 esterase 200. HP Rv 1291C NP_215807.1 DUF732 domain-containing protein 201. HP Rv 1303 NP_215819.1 ATP synthase subunit 202. HP Rv 1312 NP_215828.1 putative secreted protein 203. HP Rv 1339 NP_215855.1 metal-dependent hydrolase of the beta- lactamase III 204. HP Rv 1354C NP_215870.1 bifunctionaldiguanylatecyclase/phosphodiest erase 205. HP Rv 1357C NP_215873.1 EAL domain-containing protein 206. HP Rv 1366 NP_215882.1 RelA/SpoT domain protein 207. HP Rv 1367C NP_215883.1 beta-lactamase 208. HP Rv 1376 NP_215892.1 TfuA-like protein 209. HP Rv 1378C NP_215894.1 HNH endonuclease 210. HP Rv 1382 NP_215898.1 Transporter 211. HP Rv 1413 NP_215929.1 alanine racemase 212. HP Rv 1414 NP_215930.1 alanine racemase 213. HP Rv 1419 NP_215935.1 ricin-type beta-trefoil lectin domain protein 214. HP Rv 1421 NP_215937.1 glmZ(sRNA)-inactivating NTPase 215. HP Rv 1422 NP_215938.1 gluconeogenesis factor 216. HP Rv 1428C NP_215944.1 glycerol acyltransferase 217. HP Rv 1429 NP_215945.1 putative regulatory protein 218. HP Rv 1431 NP_215947.1 membrane protein 219. HP Rv 1433 NP_215949.1 Transpeptidase 220. HP Rv 1439C NP_215955.1 SnoaL-like domain protein 221. HP Rv 1444C NP_215960.1 ATPase 222. HP Rv 1461 NP_215977.1 Fe-S cluster assembly protein SufB 223. HP Rv 1462 NP_215978.1 Fe-S cluster assembly protein SufD 224. HP Rv 1466 NP_215982.1 metal-sulfur cluster biosynthetic enzyme 225. HP Rv 1480 NP_215996.1 VWA domain-containing protein 226. HP Rv 1487 NP_216003.1 membrane protein 227. HP Rv 1488 NP_216004.1 SPFH domain / Band 7 family protein 228. HP Rv 1501 NP_216017.1 Phytanoyl-CoA dioxygenase 229. HP Rv 1505c NP_216021.1 Transferase 230. HP Rv 1506c NP_216022.1 SAM-dependent methyltransferase 231. HP Rv 1507c NP_216023.1 WbqC-like protein 232. HP Rv 1509 NP_216025.1 membrane protein 233. HP Rv 1515c NP_216031.1 bifunctional 3-demethylubiquinone-9 3- methyltransferase/ 2-octaprenyl-6-hydroxy phenol methylase 234. HP Rv 1517 NP_216033.1 membrane protein 235. HP Rv 1518 NP_216034.1 glycosyltransferase family protein 236. HP Rv 1519 NP_216035.1 perosaminesynthetase 237. HP Rv 1531 NP_216047.1 carboxymuconolactone decarboxylase 238. HP Rv 1532c NP_216048.1 Thioesterase 239. HP Rv 1546 NP_216062.1 polyketidecyclase/dehydrase and lipid transport 240. HP Rv 1558 NP_216074.1 Nitroreductase 241. HP Rv 1565c NP_216081.1 Acyltransferase 242. HP Rv 1566c NP_216082.1 NLP/P60 family protein 243. HP Rv 1587c NP_216103.2 REP13E12 repeat-containing protein 244. HP Rv 1588c NP_216104.1 13E12 repeat family protein 245. HP Rv 1592c NP_216108.1 Lipase 246. HP Rv 1593c NP_216109.1 NUDIX hydrolase 247. HP Rv 1597 NP_216113.1 methyltransferase type 11 248. HP Rv 1598c NP_216114.1 Nitroreductase 249. HP Rv 1616 NP_216132.1 membrane protein 250. HP Rv 1619 NP_216135.1 membrane protein 251. HP Rv 1628c NP_216144.1 benzoylsuccinyl-CoA thiolase 252. HP Rv 1637c NP_216153.1 metallo-beta-lactamase superfamily protein 253. HP Rv 1639c NP_216155.1 membrane protein 254. HP Rv 1670 NP_216186.1 acyl-CoA thioesterase 255. HP Rv 1673c NP_216189.1 transglutaminase domain-containing protein 256. HP Rv 1676 NP_216192.1 AhpC/TSA family 257. HP Rv 1680 NP_216196.1 phosphate ABC transporter substrate-binding protein 258. HP Rv 1682 NP_216198.1 coiled-coil structural protein 259. HP Rv 1684 NP_216200.1 protein YcaR in KDO2-Lipid A biosynthesis cluster 260. HP Rv 1685c NP_216201.1 TetR family transcriptional regulator 261. HP Rv 1697 NP_216213.1 thiamine pyrophosphokinase 262. HP Rv 1702c NP_216218.1 DUF222 domain-containing protein 263. HP Rv 1716 NP_216232.1 Cyclase 264. HP Rv 1717 NP_216233.1 Cupin 265. HP Rv 1718 NP_216234.1 3-keto-5-aminohexanoate cleavage protein 266. HP Rv 1725c NP_216241.1 transcriptional regulator 267. HP Rv 1727 NP_216243.1 TIGR03086 family protein 268. HP Rv 1732c NP_216248.1 thioredoxin family protein 269. HP Rv 1734c NP_216250.1 pyruvate dehydrogenase E2 component 270. HP Rv 1761c NP_216277.1 DUF5073 domain-containing protein 271. HP Rv 1762c NP_216278.1 heavy-metal-binding family protein 272. HP Rv 1765c NP_216281.1 IclR family transcriptional regulator 273. HP Rv 1766 NP_216282.1 transposase 274. HP Rv 1767 NP_216283.1 Alkyl hydroperoxidereductaseAhpD 275. HP Rv 1769 NP_216285.1 alanine racemase 276. HP Rv 1770 NP_216286.1 Peptidase family M28 277. HP Rv 1772 NP_216288.1 antitermination regulator 278. HP Rv 1794 NP_216310.1 ESX secretion-associated protein EspG 279. HP Rv 1804c NP_216320.1 glycine cleavage system protein P 280. HP Rv 1810 NP_216326.1 PF05305 family protein 281. HP Rv 1813c NP_216329.1 putative open reading frame 282. HP Rv 1823 NP_216339.1 membrane associated protein 283. HP Rv 1824 NP_216340.1 integral membrane protein 284. HP Rv 1825 NP_216341.1 Division initiation protein 285. HP Rv 1836c NP_216352.1 von Willebrand factor%2C type A 286. HP Rv 1841c NP_216357.1 membrane protein 287. HP Rv 1842c NP_216358.1 membrane protein 288. HP Rv 1864c NP_216380.1 molybdenum cofactor biosysynthesis protein 289. HP Rv 1866 NP_216382.1 CoA transferase 290. HP Rv 1868 NP_216384.1 UDP-glucose 4-epimerase GalE4 291. HP Rv 1871c NP_216387.1 deazaflavin-dependent nitroreductase 292. HP Rv 1873 NP_216389.1 Calpastatin 293. HP Rv 1875 NP_216391.1 pyridoxamine 5'-phosphate oxidase 294. HP Rv 1879 NP_216395.1 amidohydrolase 295. HP Rv 1883c NP_216399.1 Cyclase 296. HP Rv 1890c NP_216406.1 Putative S-adenosyl-L-methionine-dependent methyltransferase 297. HP Rv 1894c NP_216410.1 Monooxygenase 298. HP Rv 1898 NP_216414.1 S-adenosyl-L-methionine-dependent methyl transferase 299. HP Rv 1904 NP_216420.1 anti-anti-sigma factor 300. HP Rv 1910c NP_216426.1 phosphatidylethanolamine-binding protein 301. HP Rv 1913 NP_216429.1 MBL fold metallo-hydrolase 302. HP Rv 1919c NP_216435.1 polyketidecyclase 303. HP Rv 1944c NP_216460.1 SEC-C motif domain-containing protein 304. HP Rv 1945 NP_216461.1 PF02720 domain protein 305. HP Rv 1975 NP_216491.1 Cysteine-rich secretory protein family 306. HP Rv 1976c NP_216492.1 RNA-binding protein 307. HP Rv 1977 NP_216493.1 Zn-dependent protease 308. HP Rv 1978 NP_216494.1 methyltransferase type 11 309. HP Rv 1993c NP_216509.1 PF07371 family protein 310. HP Rv 1998c NP_216514.1 PEP phosphonomutase-like enzyme 311. HP Rv 2001 NP_216517.1 acyl-ACP thioesterase%2C FatA 312. HP Rv 2003 NP_216519.1 Methyltransferase domain 313. HP Rv 2004c NP_216520.1 Predicted kinase 314. HP Rv 2008c NP_216524.1 ATPase AAA+ superfamily protein 315. HP Rv 2012 NP_216528.1 DUF1398 domain-containing protein 316. HP Rv 2015c NP_216531.1 IclR family transcriptional regulator 317. HP Rv 2018 NP_216534.1 Chain A, X-ray Crystal Structure Of Rv2018 From Mycobacterium Tuberculosis 318. HP Rv 2022c NP_216538.1 diaminopimelate decarboxylase 319. HP Rv 2030c NP_216546.1 erythromycin esterase 320. HP Rv 2035 NP_216551.1 ATPase 321. HP Rv 2036 NP_216552.1 DinB family protein 322. HP Rv 2042c NP_216558.1 pyrazinamidase/nicotinamidaspncA 323. HP Rv 2044c NP_216560.1 membrane protein 324. HP Rv 2047c NP_216563.1 UDP-glucose 4-epimerase GalE4 325. z HP Rv 2052c NP_216568.1 amidohydrolase 326. HP Rv 2054 NP_216570.1 Carboxymethylenebutenolidase 327. HP Rv 2059 NP_216575.1 zinc/manganese transporter substrate-binding protein 328. HP Rv 2061c NP_216577.1 PPOX class F420-dependent oxidoreductase 329. HP Rv 2067c NP_216583.1 asparaginyl-tRNAsynthetase 330. HP Rv 2086 NP_216602.2 Transposase 331. HP Rv 2102 NP_216618.1 SWIM zinc finger 332. HP Rv 2119 NP_216635.1 recombinaseRecB 333. HP Rv 2125 NP_216641.1 carboxylate--amine ligase 334. HP Rv 2132 NP_216648.1 DNA-binding protein, CopG family 335. HP Rv 2135c NP_216651.1 phosphoglyceratemutase 336. HP Rv 2140c NP_216656.1 Chain A, Structure Of Rv2140c, A Phosphatidyl-ethanolamine Binding Protein From Mycobacterium Tuberculosis In Complex With Sulphate 337. HP Rv 2143 NP_216659.1 phosphoribosyltransferase 338. HP Rv 2148c NP_216664.1 YggS family pyridoxal phosphate enzyme 339. HP Rv 2159c NP_216675.1 alkylhydroperoxidaseAhpD family core domain-containing protein 340. HP Rv 2161c NP_216677.1 LLM class F420-dependent oxidoreductase 341. HP Rv 2184c NP_216700.1 membrane protein, arsenite-transporting ATPase 342. HP Rv 2185c NP_216701.1 Cyclase 343. HP Rv 2191 NP_216707.1 exonuclease, DNA polymerase III, epsilon subunit 344. HP Rv 2204c NP_216720.1 HesB/YadR/YfhF family protein 345. HP Rv 2205c NP_216721.1 glycerate kinase 346. HP Rv 2226 NP_216742.1 CHAD domain-containing protein 347. HP Rv 2229c NP_216745.1 Zn-ribbon protein%2C possibly nucleic acid- binding protein 348. HP Rv 2237 NP_216753.1 FadD27 349. HP Rv 2239c NP_216755.1 DUF3052 domain-containing protein 350. HP Rv 2242 NP_216758.1 PucR family transcriptional regulator 351. HP Rv 2257c NP_216773.1 transcriptional regulator 352. HP Rv 2260 NP_216776.1 metallo-beta-lactamase superfamily protein 353. HP Rv 2267c NP_216783.1 sulfotransferase family protein 354. HP Rv 2271 NP_216787.1 Lipoprotein 355. HP Rv 2286c NP_216802.1 2-hydroxychromene-2-carboxylate isomerase 356. HP Rv 2292c NP_216808.1 nucleoside phosphorylase 357. HP Rv 2302 NP_216818.1 Chain A, Solution Structure Of The Conserved Hypothetical Protein Rv2302 From The Bacterium Mycobacterium Tuberculosis 358. HP Rv 2307c NP_216823.1 alpha/beta superfamily hydrolase 359. HP Rv 2314c NP_216830.1 Peptidase 360. HP Rv 2315c NP_216831.1 peptidase C69 361. HP Rv 2323c NP_216839.1 N-dimethylargininedimethylaminohydrolase 362. HP Rv 2325c NP_216841.1 cobalt/nickel transporter permease 363. HP Rv 2327 NP_216843.1 MarR family transcriptional regulator 364. HP Rv 2370c NP_216886.1 transcriptional activator protein 365. HP Rv 2377c NP_216893.1 protein mbtH 366. HP Rv 2387 NP_216903.1 sodium-dependent bicarbonate transport family permease 367. HP Rv 2405 NP_216921.1 mRNA interferasePemK 368. HP Rv 2406c NP_216922.1 CBS domain-containing protein, histidine kinase 369. HP Rv 2409c NP_216925.1 transglutaminase domain-containing protein 370. HP Rv 2411c NP_216927.1 carboxylate-amine ligase%2C YbdK family 371. HP Rv 2413c NP_216929.1 DNA polymerase III delta subunit 372. HP Rv 2414c NP_216930.1 competence protein 373. HP Rv 2415c NP_216931.1 membrane protein 374. HP Rv 2418c NP_216934.1 Lysophospholipase 375. HP Rv 2420c NP_216936.1 ribosome silencing factor RsfS 376. HP Rv 2423 NP_216939.1 methyltransferase type 12 377. HP Rv 2425c NP_216941.1 protein containing von Willebrand factor type A (vWA) domain 378. HP Rv 2426c NP_216942.1 ATPase 379. HP Rv 2466c NP_216982.1 Chain A, Rv2466c Mediates The Activation Of Tp053 To Kill Replicating And Non- Replicating Mycobacterium Tuberculosis 380. HP Rv 2468c NP_216984.1 DUF5130 domain-containing prote 381. HP Rv 2469c NP_216985.1 HNH endonuclease 382. HP Rv 2475c NP_216991.1 Thioesterase 383. HP Rv 2478c NP_216994.1 single-strand DNA-binding protein 384. HP Rv 2507 NP_217023.1 proline rich membrane protein 385. HP Rv 2510c NP_217026.1 ATPase 386. HP Rv 2515c NP_217031.1 Zn peptidase 387. HP Rv 2522c NP_217038.1 acetylornithinedeacetylaseArgE 388. HP Rv 2525c NP_217041.1 Chain A, Crystal Structure Of The Mycobacterium Tuberculosis Tat-secreted Protein Rv2525c, Monoclinic Crystal Form 389. HP Rv 2542 NP_217058.1 lipoprotein LppA 390. HP Rv 2551c NP_217067.1 prepilin peptidase 391. HP Rv 2556c NP_217072.1 secondary thiamine-phosphate synthase enzyme 392. HP Rv 2559c NP_217075.1 AAA family ATPase 393. HP Rv 2566 NP_217082.1 transglutaminase family protein 394. HP Rv 2569c NP_217085.1 transglutaminase domain-containing protein 395. HP Rv 2574 NP_217090.1 MxaD family protein 396. HP Rv 2577 NP_217093.1 metallophosphoesteras 397. HP Rv 2578c NP_217094.1 radical SAM protein 398. HP Rv 2598 NP_217114.1 Toxin 399. HP Rv 2616 NP_217132.1 DUF1990 domain-containing protein 400. HP Rv 2630 NP_217146.1 Archease 401. HP Rv 2638 NP_217154.1 anti-anti-sigma factor 402. HP Rv 2647 NP_217163.2 phiRv1 phage protein 403. HP Rv 2670c NP_217186.1 ATPase 404. HP Rv 2675c NP_217191.1 thiopurine S-methyl transferase 405. HP Rv 2676c NP_217192.1 chlorite dismutase 406. HP Rv 2681 NP_217197.1 3'-5' exonuclease 407. HP Rv 2683 NP_217199.1 CBS domain-containing protein 408. HP Rv 2689c NP_217205.1 23S rRNA methyltransferase 409. HP Rv 2695 NP_217211.1 alpha/beta hydrolase family protein 410. HP Rv 2699 NP_217215.1 dUTPase 411. HP Rv 2700 NP_217216.1 secreted alanine rich protein 412. HP Rv 2704 NP_217220.1 endoribonuclease L-PSP 413. HP Rv 2705c NP_217221.1 glutathione S-transferase 414. HP Rv 2707 NP_217223.1 ribonuclease BN 415. HP Rv 2714 NP_217230.1 proteasome protein 416. HP Rv 2716 NP_217232.1 thymidylate synthase 417. HP Rv 2717c NP_217233.1 FABP family protein 418. HP Rv 2721c NP_217237.1 transmembrane alanine/glycine-rich protein 419. HP Rv 2731 NP_217247.1 DNA repair ATPase 420. HP Rv 2734 NP_217250.1 phage Gp37Gp68 family protein 421. HP Rv 2738c NP_217254.1 Transferase 422. HP Rv 2742c NP_217258.1 arginine rich protein 423. HP Rv 2749 NP_217265.1 antibiotic biosynthesis monooxygenase 424. HP Rv 2751 NP_217267.1 methyltransferase 425. HP Rv 2777c NP_217293.1 metal-dependent hydrolase 426. HP Rv 2778c NP_217294.1 polyketidecyclase/dehydrase and lipid transport 427. HP Rv 2787 NP_217303.1 putative alanine rich protein 428. HP Rv 2795c NP_217311.1 metallophosphoesterase 429. HP Rv arginine NP_217318.1 putative arginine and alanine rich protein 430. HP Rv 2807 NP_217323.1 integrase 431. HP Rv 2813 NP_217329.1 AAA family ATPase 432. HP Rv 2827c NP_217343.1 Chain A, Crystal Structure Of Rv2827c Protein From Mycobacterium Tuberculosis 433. HP Rv 2840c NP_217356.3 DNA-binding protein 434. HP Rv 2844 NP_217360.1 Chain A, Crystal Structure Of A Conserved Hypothetical Protein, Rv2844, From Mycobacterium Tuberculosis 435. HP Rv 2854 NP_217370.1 lysophospholipase 436. HP Rv 2891 NP_217407.1 M23 peptidase domain-containing protein 437. HP Rv 2896c NP_217412.1 DNA protecting protein DprA 438. HP Rv 2897c NP_217413.1 magnesium chelatase 439. HP Rv 2898c NP_217414.1 putative endonuclease 440. HP Rv 2908c NP_217424.1 putative RNA-binding protein (contains KH domain) 441. HP Rv 2910c NP_217426.1 snoaL-like domain protein 442. HP Rv 2915c NP_217431.1 Amidohydrolase 443. HP Rv 2917 NP_217433.1 alanine and arginine rich protein 444. HP Rv 2923c NP_217439.1 putative redox protein%2C regulator of disulfide bond formation [Mycobacterium tuberculosis] 445. HP Rv 2926c NP_217442.1 putative metal-binding protein%2C possibly nucleic-acid binding protein 446. HP Rv 2955c NP_217471.1 methyltransferase 447. HP Rv 2956 NP_217472.1 FkbM family methyltransferase 448. HP Rv 2969c NP_217485.1 membrane protein 449. HP Rv 2972c NP_217488.1 membrane or exported protein 450. HP Rv 2974c NP_217490.1 dihydroxyacetone kinase 451. HP Rv 2980 NP_217496.1 secreted protein 452. HP Rv 2991 NP_217507.1 PPOX class F420-dependent enzyme 453. HP Rv 3005c NP_217521.1 membrane protein 454. HP Rv 3015c NP_217531.1 methionine synthase 455. HP Rv 3026c NP_217542.1 1-acyl-sn-glycerol-3-phosphate acyltransferase 456. HP Rv 3035 NP_217551.1 pyrrolo-quinolinequinone 457. HP Rv 3036c NP_217552.1 putative secreted protein 458. HP Rv 3038c NP_217554.1 Methyltransferase 459. HP Rv 3046c NP_217562.1 endonuclease 460. HP Rv 3054c NP_217570.1 FMN reductase 461. HP Rv 3067c NP_217583.1 putative secreted protein 462. HP Rv 3072c NP_217588.1 LLM class F420-dependent oxidoreductas 463. HP Rv 3074 NP_217590.1 HNH endonuclease 464. HP Rv 3075c NP_217591.1 citrate lyase subunit beta 465. HP Rv 3076 NP_217592.1 Cyclase 466. HP Rv 3079c NP_217595.1 5,10-methylenetetrahydromethanopterin reductase 467. HP Rv 3081 NP_217597.1 Nucleotidyltransferase of uncharacterised function 468. HP Rv 3090 NP_217606.1 alanine/valine-rich protein 469. HP Rv 3091 NP_217607.1 putative esterase of the alpha-beta hydrolase superfamily 470. HP Rv 3094c NP_217610.1 Hydroxylase 471. HP Rv 3114 NP_217630.1 cytidine and deoxycytidylatedeaminase family protein 472. HP Rv 3120 NP_217636.1 Methyltransferase 473. HP Rv 3163c NP_217679.1 ATPase 474. HP Rv 3179 NP_217695.1 ATPase AAA+ superfamily protein 475. HP Rv 3182 NP_217698.1 DNA-binding protein 476. HP Rv 3189 NP_217705.1 RES domain-containing protein 477. HP Rv 3192 NP_217708.1 alanine/proline-rich protein 478. HP Rv 3194c NP_217710.1 signal protein PDZ 479. HP Rv 3195 NP_217711.1 hydrolase 480. HP Rv 3207c NP_217723.1 membrane protein 481. HP Rv 3209c NP_217725.1 threonine AND proline RICH protein 482. HP Rv 3210c NP_217726.1 Hydroxylase 483. HP Rv 3218 NP_217734.1 diacylglycerol kinase catalytic subunit 484. HP Rv 3221c NP_217737.1 acetyl-CoA carboxylase biotin carboxyl carrier protein subunit 485. HP Rv 3226c NP_217742.1 DUF159 family protein 486. HP Rv 3228 NP_217744.1 ribosome small subunit-dependent GTPase A 487. HP Rv 3237c NP_217754.1 potassium transporter TrkA 488. HP Rv 3241c NP_217758.1 ribosomal subunit interface protein 489. HP Rv 3259 NP_217776.1 exonuclease 490. HP Rv 3267 NP_217784.1 LytR family transcriptional regulator 491. HP Rv 3269 NP_217786.1 TIGR03089 family protein 492. HP Rv 3272 NP_217789.1 CoA transferase 493. HP Rv 3282 NP_217799.1 septum formation inhibitor Maf 494. HP Rv 3284 NP_217801.1 cysteine desufuration protein SufE 495. HP Rv 3292 NP_217809.1 DUF1338 domain-containing protein 496. HP Rv 3300c NP_217817.1 Pseudouridine synthase 497. HP Rv 3304 NP_217821.1 gamma-glutamylcyclotransferase 498. HP Rv 3312c NP_217829.1 alpha/beta fold family hydrolase 499. HP Rv 3333c NP_217850.1 proline-rich protein 500. HP Rv 3351c NP_217868.1 oxidoreductase 501. HP Rv 3354 NP_217871.1 Lipoprotein 502. HP Rv 3360 NP_217877.1 ABC transporter ATP-binding/permease protein 503. HP Rv 3361c NP_217878.1 pentapeptide repeat protein MfpA 504. HP Rv 3364c NP_217881.1 dynein regulation protein LC7 505. HP Rv 3365c NP_217882.1 histidine kinase [ 506. HP Rv 3369 NP_217886.1 Pyridoxamine 5'-phosphate oxidase 507. HP Rv 3394c NP_217911.1 DNA polymerase 508. HP Rv 3402c NP_217919.1 perosaminesynthetase 509. HP Rv 3404c NP_217921.1 methionyl-tRNAformyltransferase 510. HP Rv 3421c NP_217938.1 ribosomal-protein-alanine acetyltransferaserimI 511. HP Rv 3463c NP_217980.1 LLM class F420-dependent oxidoreductase 512. HP Rv 3466 NP_217983.1 13E12 repeat family protein 513. HP Rv 3472 NP_217989.1 SnoaL-like polyketidecyclas 514. HP Rv 3483c NP_218000.1 LppP/LprE lipoprotein 515. HP Rv 3484 NP_218001.1 transcriptional regulator, LytR family prote 516. HP Rv 3488 NP_218005.1 PadR family transcriptional regulator 517. HP Rv 3510c NP_218007.1 amidohydrolase 518. HP Rv 3519 NP_218016.1 acetoacetate decarboxylase 519. HP Rv 3521 NP_218018.1 DNA-binding protein 520. HP Rv 3529c NP_218046.1 Sulfotransferase 521. HP Rv 3542c NP_218059.1 putative nucleic-acid-binding protein 522. HP Rv 3555c NP_218072.1 cullin%2C a subunit of E3 ubiquitin ligase 523. HP Rv 3594 NP_218111.1 peptidoglycan-binding domain 1 protein 524. HP Rv 3603c NP_218120.1 Oxidoreductase 525. HP Rv 3605c NP_218122.1 membrane protein 526. HP Rv 3626c NP_218143.1 Hydrolase 527. HP Rv 3627c NP_218144.1 D-alanyl-D-alanine carboxypeptidase 528. HP Rv 3633 NP_218150.1 Phytanoyl-CoA dioxygenase 529. HP Rv 3654c NP_218171.2 Helicase 530. HP Rv 3656c NP_218173.2 membrane protein 531. HP Rv 3661 NP_218178.1 HAD hydrolase%2C family I 532. HP Rv 3672c NP_218189.1 coenzyme A pyrophosphatase 533. HP Rv 3678c NP_218195.1 LysR family transcriptional regulator 534. HP Rv 3683 NP_218200.1 Metallophosphoesterase 535. HP Rv 3688c NP_218205.1 glutamyl-tRNAamidotransferase 536. HP Rv 3691 NP_218208.1 membrane protein 537. HP Rv 3699 NP_218216.1 SAM-dependent methyltransferase 538. HP Rv 3705c NP_218222.1 sensor domain-containing protein 539. HP Rv 3707c NP_218224.1 putative secreted protein 540. HP Rv 3716c NP_218233.1 nucleoid-associated protein 541. HP Rv 3717 NP_218234.1 N-acetylmuramoyl-L-alanine amidase 542. HP Rv 3718c NP_218235.1 polyketidecyclase 543. HP Rv 3719 NP_218236.1 FAD binding domain-containing protein 544. HP Rv 3722c NP_218239.1 aspartate transaminase 545. HP Rv 3730c NP_218247.1 DNA ligase D 546. HP Rv 3733c NP_218250.1 NTP pyrophosphohydrolase 547. HP Rv 3735 NP_218252.1 Adenosine specific kinase 548. HP Rv 3755c NP_218272.1 glycine/betaine ABC transporter permease 549. HP Rv 3768 NP_218285.1 polyketidecyclase 550. HP Rv 3776 NP_218293.1 putative HNH endonuclease domain protein 551. HP Rv 3786c NP_218303.1 peptidase M23B 552. HP Rv 3788 NP_218305.1 nucleoside diphosphate kinase regulator 553. HP Rv 3813c NP_218330.1 HAD family hydrolase 554. HP Rv 3818 NP_218335.1 UDP-MurNAc hydroxylase%2C NamH 555. HP Rv 3822 NP_218339.1 PE-PPE domain-containing protein 556. HP Rv 3835 NP_218352.1 cell division protein, Z-ring complex Ib 557. HP Rv 3836 NP_218353.1 putative zinc metalloproteas 558. HP Rv 3856c NP_218373.1 PHP domain-containing protei 559. HP Rv 3860 NP_218377.1 ATPase 560. HP Rv 3902c NP_218419.1 Chain A, Atomic Structure Of Tuberculosis Necrotizing Toxin (tnt) Complexed With Its Immunity Factor Ift 561. HP Rv 3903c NP_218420.1 alanine and proline rich protein 562. HP Rv 3920c NP_218437.1 single-stranded DNA-binding protein 563. HP Rv 1228a YP_009030032.1 prevent-host-death family protein 564. HP Rv 1984a YP_009030034.1 PE-PGRS family protein 565. HP Rv 0164 YP_177617.1 Cyclase 566. HP Rv 0236A YP_177619.1 DUF2613 domain-containing protein 567. HP Rv 0634A YP_177629.1 antitoxin VapB 568. HP Rv 1322A YP_177643.1 methylmalonyl-CoA epimerase 569. HP Rv 1498A YP_177647.1 methylmalonyl-CoA mutase 570. HP Rv 1508A YP_177649.1 GDP-D-mannose dehydratase 571. HP Rv 0787A YP_177755.1 phosphoribosylformylglycinamidine synthase subunit PurS 572. HP Rv 1000C YP_177777.1 DNA repair protein 573. HP Rv 1342C YP_177800.1 membrane protein 574. HP Rv 1860 YP_177849.1 alanine and proline-rich secreted protein Apa 575. HP Rv 2141C YP_177864.1 carboxypeptidase PM20D1 576. HP Rv 3294C YP_177954.1 ATPase AAA+ superfamily protein 577. HP Rv 3796 YP_178016.1 metal-dependent hydrolase 578. HP Rv 3811 YP_178018.1 cold-shock protein</p>