<p> Selected Bibliography of Presentation</p><p>“Life’s Mirror: New Ways of Understanding and Treating Alzheimer’s Disease”</p><p>Barry Reisberg, M.D. Professor Department of Psychiatry Clinical Director Silberstein Aging and Dementia Research Center New York University School of Medicine</p><p>1. Reisberg, B., Ferris, S.H., de Leon, M.J., & Crook, T. (1982). The global deterioration scale for assessment of primary degenerative dementia. American Journal of Psychiatry, 139, 1136-1139. </p><p>2. Reisberg, B., Ferris, S.H., de Leon, M.J., & Crook, T. (1988). The Global Deterioration Scale (GDS). Psychopharmacology Bulletin, 24, 661-663. </p><p>3. Reisberg, B., & Ferris, S.H. (1988). The Brief Cognitive Rating Scale (BCRS). Psychopharmacology Bulletin, 24, 629-636. </p><p>4. Reisberg, B., Ferris, S.H., & Franssen, E. (1985). An ordinal functional assessment tool for Alzheimer's-type dementia. Hospital and Community Psychiatry, 36, 593-595. </p><p>5. Reisberg, B. (1988). Functional assessment staging (FAST). Psychopharmacology Bulletin, 24, 653-659. </p><p>6. Sclan, S.G., & Reisberg, B. (1992). Functional assessment staging (FAST) in Alzheimer's disease: Reliability, validity and ordinality. International Psychogeriatrics, 4 (Supp.1), 55-69. </p><p>7. Flicker, C., Ferris, S.H., & Reisberg, B. (1993). A two-year longitudinal study of cognitive function in normal aging and Alzheimer's disease. Journal of Geriatric Psychiatry and Neurology, 6, 84-96. </p><p>8. Prichep, L.S., John, E.R., Ferris, S.H., Reisberg, B., Alper, K., Almas, M., & Cancro, R. (1994). Quantitative EEG correlates of cognitive deterioration in the elderly. Neurobiology of Aging, 15, 85-90. </p><p>9. Franssen, E.H., Reisberg, B., Kluger, A., Sinaiko, E., & Boja, C. (1991). Cognition-independent neurologic symptoms in normal aging and probable Alzheimer's disease. Archives of Neurology, 48, 148-154. 10. Franssen, E.H., Kluger, A., Torossian, C.L., & Reisberg, B. (1993). The neurologic syndrome of severe Alzheimer's disease: Relationship to functional decline. Archives of Neurology, 50, 1029-1039. </p><p>11. Reisberg, B., Sclan, S.G., Franssen, E., de Leon, M.J., Kluger, A., Torossian, C., Shulman, E., Steinberg, G., Monteiro, I., McRae, T., Boksay, I., Mackell, J., & Ferris, S.H. (1993). Clinical stages of normal aging and Alzheimer's disease: The GDS staging system. Neuroscience Research Communications, 13 (Suppl. 1), 551-554. </p><p>12. Reisberg, B., Borenstein, J., Salob, S.P., Ferris, S.H., Franssen, E., & Georgotas, A. (1987). Behavioral symptoms in Alzheimer's disease: Phenomenology and treatment. Journal of Clinical Psychiatry, 48 (Suppl.), 9-15. </p><p>13. Reisberg, B., Franssen, E., Sclan, S.G., Kluger, A., & Ferris, S.H. (1989). Stage specific incidence of potentially remediable behavioral symptoms in aging and Alzheimer's disease: A study of 120 patients using the BEHAVE-AD. Bulletin of Clinical Neurosciences, 54, 95-112. </p><p>14. Reisberg, B. (1986). Dementia: A systematic approach to identifying reversible causes. Geriatrics, 41 (4), 30-46. </p><p>15. Auer, S.R., Sclan, S.G., Yaffee, R.A., & Reisberg, B. The neglected half of Alzheimer's disease: Cognitive and functional concomitants of severe dementia. Journal of the American Geriatrics Society, 42 (12),1229-1329), 1994.</p><p>16. Bobinski, M., Wegiel, J., Wisniewski, H.M., Tarnawski, M., Reisberg, B., Mlodzik, G., de Leon, M.J., Miller, D.C. Atrophy of hippocampal formation subdivisions correlates with stage and duration of Alzheimer disease Dementia (in press) (1995). </p><p>17. Souren, L.E.M., Franssen, E.M., Reisberg, B. Contractures and loss of function in patients with Alzheimer's disease. Journal of the American Geriatrics Society,.1995, 43:650-655.</p><p>18. Reisberg, B., Franssen, E., Bobinski, M., Auer, S., Monteiro, I., Boksay, I., Wegiel, J., Shulman, E., Steinberg, G., Souren, L., Kluger, A., Torossian, C., Sinaiko, E., Wisnieski, H.M, Ferris, S.H. Overview of methodologic issues for pharmacologic trials in mild, moderate, and severe Alzheimer's disease. International Psychogeriatrics, 1996, 8:159- 193.</p><p>19. Auer, S.R., Monteiro, I.M., Reisberg, B. The Empirical Behavioral Pathology in Alzheimer's Disease (E-BEHAVE-AD) Rating Scale. International Psychogeriatrics, 1996, 8:247-266. 20. Reisberg, B., Ferris, S.H., Franssen, E., Shulman, E., Monteiro, I., Sclan, S.G., Steinberg, G., Kluger, A., Torossian, C., de Leon, M.J., Laska, E. Mortality and temporal course of probable Alzheimer's disease: A five-year prospective study. International Psychogeriatrics, 1996, 8:291- 311.</p><p>21. Sclan, S.G., Saillon, A., Franssen, E., Hugonot-Diener, L., Saillon, A., Reisberg, B. The Behavioral Pathology in Alzheimer's Disease Rating Scale (BEHAVE-AD): Reliability and analysis of symptom category scores. International Journal of Geriatric Psychiatry, 1996, 11:819-830.</p><p>22. Kluger, A., Gianutsos, J.G., Golomb, J., Ferris, S.H., George, A.E., Franssen, E., Reisberg, B. Patterns of motor impairment in normal aging, mild cognitive decline and early Alzheimer's disease. Journal of Gerontology: Psychological Sciences, 1997, 52B:P28-P39.</p><p>23. Franssen, E.H., Souren, L.E.M., Torossian, C.L., Reisberg, B. Utility of developmental reflexes in the differential diagnosis and prognosis of incontinence in Alzheimer's disease. Journal of Geriatric Psychiatry and Neurology, 1997, 10:22- 28.</p><p>24. Bobinski, M., Wegiel. J., Tarnawski, M., Bobinski, M., Reisberg, B., de Leon, M.J., Miller, D.C., Wisniewski, H.M. Relationships between regional neuronal loss and neurofibrillary changes in the hippocampal formation and duration and severity of Alzheimer disease, Journal of Neuropathology and Experimental Neurology, 1997, 56:414-420.</p><p>25. Souren, L.E.M., Franssen, E.H., Reisberg, B. Neuromotor changes in Alzheimer's disease: Implications for patient care. Journal of Geriatric Psychiatry and Neurology, 1997, 10:93-98.</p><p>26. Franssen, E.H., Reisberg, B. Neurologic markers of the progression of Alzheimer's disease. International Psychogeriatrics, 1997, 9(Suppl. 1):297-306.</p><p>27. Reisberg, B., Auer, S.R., Monteiro, I., Fransen, E., Kenowsky, S. A rational psychological approach to the treatment of behavioral disturbances and symptomatology in Alzheimer's disease based upon recognition of the developmental age. International Academy for Biomedical and Drug Research, 1998, 13:102-109.</p><p>28. Reisberg, B., Franssen, E., Souren, L.E.M., Auer, S., Kenowsky, S. Progression of Alzheimer's disease: Variability and consistency: Ontogenic models, their applicability and relevance. Journal of Neural Transmission, 1998 [Suppl.] 54:9-20.</p><p>29 Reisberg, B., Kenowsky, S., Franssen, E.H., Auer, S.R., Souren, L.E.M., President's Report: Towards a science of Alzheimer's disease management: A model based upon current knowledge of retrogenesis. International Psychogeriatrics, 1999, 11:7- 23.</p><p>30. Reisberg, B., Franssen, E.H., Hasan, S.M., Monteiro, I., Boksay, I., Souren, L.E.M., Kenowsky, S., Auer, S.R., Elahi, S., Kluger, A. Retrogenesis: clinical, physiologic and pathologic mechanisms in brain aging, Alzheimer's and other dementing processes, European Archives of Psychiatry and Clinical Neuroscience, 1999, 249 (Suppl. 3): 28-36. Czech translation published as follows: Reisberg, B., Franssen, E.H., Hasan, S.M., Monteiro, I., Boksay, I., Souren, L.E.M., Kenowsky, S., Auer, S.R., Elahi, S., Kluger, A. Retrogeneze: Klinické, fyziologické a patologické mechanismy při stárnuti mozku, Alheimerově nemoci a jinych demencich, Forum Medicinae, 2000 (2):39-47.</p><p>31. Reisberg, B., Franssen, E.H., Souren, L.E.M., Auer, S.R., Akram, I., Kenowsky, S. Evidence and mechanisms of retrogenesis in Alzheimer’s and other dementias: Management and treatment import. American Journal of Alzheimer’s Disease, 2002, 17:202-212.</p><p>32. Franssen, E.H., souren, L.E.M., Torossian, C.L., Reisberg, B., Equilibrium and limb coordination in mild cognitive impairment and mild Alzheimer's disease, Journal of the American Geriatrics Society, 1999, 47:463-499.</p><p>33. Reisberg, B., Franssen, E.H.Clinical stages of Alzheimer's disease. In: An Atlas of Alzheimer's Disease, M.J. de Leon, (Ed.), Carnforth (UK), Parthenon, 1999, pp. 11-20.</p><p>34. Kluger, A., Ferris, S. H., Golomb, J., Mittelman, M. S., Reisberg, B. Neuropsychological prediction of decline to dementia in nondemented elderly. Journal of Geriatric Psychiatry and Neurology, 1999, 12:168-179.</p><p>35. Monteiro, I. M., Boksay, I., Auer, S. R., Torossian, C., Ferris, S. H., Reisberg, B. Addition of a frequency weighted score to the Behavioral Pathology in Alzheimer's Disease Rating Scale: The BEHAVE-AD-FW: Methodology and Reliability. European Psychiatry, 2001, 16: (Suppl. 1), 5S-24S. 36. Reisberg, B. Senile dementia. In: The Encyclopedia of Aging, Third Edition.G.L. Maddox, R.C. Atchley, J.G. Evans, R.B. Hudson, R.A. Kane, E.J. Masoro, M.D. Mezey, L.W. Poon, and I.C. Siegler (Eds.). New York: Springer, 2001, pp. 907-916. </p><p>37. Reisberg, B., Finkel, S., Overall, J., Schmidt-Gollas, N., Kanowski, S., Lehfeld, H., Hulla, F., Sclan, S.G., Wilms, H. -U., Heininger, K., Hindmarch, I., Stemmler, M., Poon, L., Kluger, A., Cooler, C., Bergener, M., Hugonot-Diener, L., Robert, P.H., Erzigkeit H. The Alzheimer’s disease Activities of Daily Living International Scale (ADL-IS). International Psychogeriatrics, 2001, 13:163-181.</p><p>38. de Leon, M.J., Convit, A., Wolf, O.T., Tarshish, C.Y., DeSanti, S., Rusinek, H., Tsui, W., Kandil, E., Scherer, A.J., Roche, A., Imossi, A., Thorn, E., Bobinski, M., Caraos, C., Lesbre, P., Schlyer, D., Poirier, J., Reisberg, B.,Fowler, J. Prediction of cognitive decline in normal elderly subjects with2-[18F] fluoro-2-deoxy- D-glucose/positron- emission tomography (FDG/PET). Proceedings of the National Academy of Sciences, 2001, 98:10966-10971. </p><p>39. Shimada, M., Hayat, J., Meguro, K., Oo, T., Jafri, S., Yamadori, A., Franssen, E.H., Reisberg, B. Correlation between functional assessment staging and the ‘Basic Age’ by the Binet scale supports the retrogenesis model of Alzheimer’s disease: a preliminary study. Psychogeriatrics, 2003, 3:82-87.</p><p>40. Reisberg, B., Doody, R., Stöffler, A., Schmitt, F., Ferris, S., Möbius, H.-J., for the Memantine Study Group. Memantine in moderate- to- severe Alzheimer’s disease. New England Journal of Medicine, 2003, 348:1333-1341.</p><p>41. Reisberg, B., Doody, R., Stöffler, A., Schmitt, F., Ferris, S., Möbius, H-J. A 24-week open-label extension study of memantine in moderate-to-severe Alzheimer’s disease. Archives of Neurology, 2006, 63: 49-54.</p><p>42. Reisberg, B., Saeed, M.U. Alzheimer’s disease. In: Comprehensive Textbook of Geriatric Psychiatry - Third Edition, J. Sadovoy, L.F. Jarvik, G.T. Grossberg and B. S. Meyers (Eds.), New York (NY): W.W. Norton, 2004, 449-509.</p><p>43. Reisberg, B., Wegiel, J., Franssen, E., Kadiyala, S., Auer, S., Souren, L., Sabbagh, M., Golomb, J., Clinical features of severe dementia: staging. In: Severe Dementia, A. Burns and B. Winblad (Eds.). London, John Wiley & Sons, 2006, 83-115.</p>