<p>Table 1. Prevalence of colic and fussing/crying in infants aged 0–12 months Study, year Country Study design No in population Ag Criteria/definition Prevalence Akman 2006 Turkey Prospective 78 0–6 Wessel criteria 22% [26] cohort Canivet 1996 Sweden Population- 376 Wessel criteria 9% [15] based Crying/fussing ≥3 h/day on 3 12% prospectiv days/week e and Crying/screaming ≥1 h/day, 4 16% retrospecti days/week, for ≥1 week ve Crying seen as a problem 9% Canivet 2004 Sweden Prospective 1094 Crying/fussing ≥3 h/day on ≥3 9.1% [14] cohort days of preceding week Castro- USA Prospective 964 0–2 Recorded on well-infant visit form 9.2% Rodriguez populatio 2001 [19] n Chouraqui 2011 France Prospective 1211 (1-4 years) 0–4 Rome III criteria 19% [6] populatio n Clifford 2002 Canada Prospective 617 0–6 Modified Wessel criteria 24% [21] cohort Cohen Engler Israel Cross- 94 2–4 Parental report of paroxysmal 56% of breast fed; 2011 [27] sectional irritability 73% of formula fed Crowcroft 1997 UK Questionnaire 67,172 Not formally defined 18.3% [8] study Fazil 2011 [24] Pakistan Prospective 426 0–6 Wessel criteria 22% cohort Forsyth 1985 USA Prospective 373 Excessive crying 21% [32] cohort Colic 11% Hide 1982 [13] UK Prospective 843 0– Not reported 16% populatio n survey Høgdall 1991 Denmark Prospective 365 0–6 Crying/fussing for ≥90 min/day for 19% [17] cohort ≥6/7 preceding days, or ≥3 h/day in ≥3/7 days Howard 2006 USA Prospective 700 Parental report 15% [22] cohort Modified Wessel criteria 2% Iacono 2005 [4] Italy Population- 2879 0–6 Crying ≥3 hours/day, ≥3 20.5% based days/week during previous 2 prospectiv weeks, accompanied by e swelling of abdomen due to intestinal gas and sleep disturbances Infante Pina Spain Cross- 3487 1– Not reported 9.2% 2008 [7] sectional Lehtonen 1995 Finland Cross- 959 0–3 Wessel criteria 13% [12] sectional Lothe 1990 [16] Sweden Prospective 219 0–3 Crying ≥3 hours/day, ≥4 17% cohort days/week for ≥1 week Rautava 1993 Finland Population 1204 0–3 Nurse/parent report 28% [10] sample Reijneveld 2005 Netherland National 5845 0–3 Crying ≥3 hours/day for ≥3 days of 4% [30] s sample previous week Rubin 1984 [9] UK Prospective 1019 0– Parental report 26% cohort Saavedra 2003 Brazil Prospective 1086 0–3 Wessel criteria 16.3% [23] cohort Stagnara 1997 France Prospective 2797 0–4 Frequent and/or unexplained 22.5% [5] crying Ståhlberg 1984 Finland Retrospective 323 Ear Unexplained periods of crying and 40% [11] questionn restlessness, mostly in the aire evenings Talachian 2008 Iran Prospective 321 0–3 Wessel criteria 20% [25] cohort Tasche 1993 Netherland Stratified 4451 0–4 Excessive crying, colic or 10% [28] s sample of restlessness GPs Thomas 1987 USA Retrospective 964 2– Recurrent episodes of unexplained 20% [20] analysis crying and irritability for ≥1 week van der Wal Netherland Questionnaire 1826 2–3 Problematic infant crying 20.3% 1998 [29] s survey Crying for ≥3 hours/24-h day 7.6% Crying a lot 14.0% Difficult to comfort 10.3% van Tilburg USA Cross- 264 (0-3 years) 0– Rome III criteria 6% 2015 [18] sectional survey Wake 2006 [33] Australia Prospective 483 Cry-fuss problems 19% cohort 13% 6% Wurmser 2001 Germany Telephone 662 0–3 Excessive crying/fussing 21% [31] survey </p>