<p>Ministry of Higher Education وزارة التعليم العالي Majmaah University جامعة المجمعة College of Applied Medical Sciences Department of Medical Laboratory ةةةة ةةةةةة ةةةةةة التطبيقية ةةة ةةةة ةةةةةةةةة الطبية WEEK (7 – 8) Name of Instructor: Dr. Omar Amer Location: Majmaah male campus MCQ: Please find the proper answer of the following: 1. Each of the following statements concerning Malaria is correct except a. The female anopheles mosquito is the vector b. Early infection, sporozoites enter hepatocytes c. Release of merozoites from red blood cells cause fever and chills d. The principal site of gametocyte formation is the human gastrointestinal tract. 2. In malaria, the form of plasmodia that is transmitted from mosquito to human is the: a. Sporozoite b. Gametocyte c. Merozoite d. Trophozoite 3. Weight loss, tenesmus, bloody stool, intestinal hemorrhage, intestinal perforation: a. How are Balantidium coli infections treated? b. How do severe Balantidium coli infections present? c. How do chronic Balantidium coli infections present?</p><p> d. How do Balantidium coli infections usually present? 4. Seeing trophozoites and cysts on a direct smear, floatation (cysts), Histopathology: a. How are Balantidium coli infections treated? b. How is Balantidium coli diagnosed? c. What is Balantidium coli? d. How can Balantidium coli infections be prevented?</p><p>1 5. Cosmopolitan, opportunistic pathogen. Ciliated protozoon known to infect humans, non-human primates, swine, dogs, birds, rats & guinea pigs. Rotary type motion and binucleated: a. How is Balantidium coli diagnosed? b. What is Balantidium coli? c. How do trophozoites reproduce? d. How does the cyst stage appear? 6. Humans, monkeys, guinea pigs, rats (cecum and colon): a. int hosts b. diagnosis</p><p> c. definitive hosts c. disease 7. Fecal-oral: a. How is B. coli transmitted? b. What is Balantidium coli? c. How would you treat B. coli? d. How is B. coli diagnosed? 8. Sanitation, Preventative measures (gloves, masks, etc), Periodic screening of carrier animals: a. What is the pathology of B. coli?</p><p> b. What are the clinical signs of B. coli?</p><p> c. How would you treat B. coli?</p><p> d. How can you prevent/control B. coli?</p><p>9. Cysts passed in feces-> trophozoites travel to cecum & colon-> encyst in digestive gut:</p><p> a. What is the pathology of B. coli?</p><p> b. Describe the life cycle of B. coli.</p><p> c. What are the clinical signs of B. coli?</p><p> d. Describe the cyst stage of B. coli.</p><p>10. Worldwide; particularly common in the Philippines and other parts of </p><p>Asia:</p><p> a. Distribution? b. Inhabits?</p><p>2</p><p> c. Treatment? d. Diagnosis?</p><p>11. i. Most asymptomatic</p><p> ii. May resemble amoebic dysentery infection iii. Persistent diarrhea, cramping, occasionally dysentery, abdominal </p><p> pain and weight loss.</p><p> iv. Symptoms can be sever in debilitated persons</p><p> v. intestinal perforation</p><p> vi. Rarely spread to other organs (liver, lung-abscesses).</p><p>1. Diagnosis? b. Inhabits? C. Cyst d. Symptoms? 12. i. molecular test: PCR detects nucleic acids </p><p> ii. Rapid tests: detect parasite antigen</p><p> iii. Parasites in blood smear (gold standard)</p><p> a. What are the main strategies for malaria control in 2012?</p><p>2. What are the direct diagnostic tests used for malaria/plasmodium?</p><p>3. What is the initial fever pattern for P. malariae? 4. What are two common clinical symptoms for malaria? 13. Infective stage to man in plasmodium: a. Sporogony b. Sporozoite</p><p> c. P. Ovale d. P. ovale 14. Significance of thick film: a. Provide a better diagnostic tool for experienced workers 1. Near the tail of the blood thin smear 2. Release of merozoites</p><p>3 3. Histidine-rich protein II 15. Mosquitos (anopheles - about 50 species): a. Intermediate hosts b. body forms c. definitive hosts d. diagnosis 16. (Leukocytes – Reticulocytes – Thrombocytes) Young red blood cells that merozoites of Plasmodium vivax invade.</p><p>17. Part of the name of the disease caused by Plasmodium vivax that is due to its fever lasting 48 hours:</p><p> a. Tertian b. Vivax c. Temperate 4. Benign 18. Associated with synchrony of merozoite release In between, </p><p> temperature is normal and patient feels well falciparum does not exhibit classical signs (continuous fever)</p><p> a. Malaria word origin</p><p> b. Malaria life cycle</p><p> c. Malaria Paroxysm</p><p> d. Malaria (treatment)</p><p>19. Pale, enlarge, numerous Shuffner's dots; all asexual stages may be seen at once (trophozoite, merozoite, schizont):</p><p> a. RBS's in P. falciparum infection</p><p> b. P. vivax and P. Ovale Parasitized Erythrocyte</p><p> c. Erythrocyte parasitized by P. ovale are</p><p> d. Possible adverse effects of TNF</p><p>20. Merozoites rapidly and specifically enter erythrocytes.</p><p>4 1. Pre-erythrocytic schizogony 2. Plasmodium ovale 3. merozoites 4. Erythrocytic phase SAQ</p><p>1. How does the trophozoite of B. coli appear? Ans.: Large (50-150um), cilia (motile), kidney or bean shaped macronucleus, cystome or gullet (mouth).</p><p>2. Compare between E. histolytica & B. coli. 3. How you can explain the disappearance of trophozoite, schizont, merozoites stages in case of Plasmodium falciparum infection. Name of Instructor: Dr. Mosaab Omar Location: Zulfi campus MCQ: 1. Which of the following statements regarding Balantidium coli is true……………….. a. Inhabits the large intestine of Human b. Moves by Cilia c.Multiply both sexually and a sexually d.Has two nuclei (Macro and micro nuclei) e.All of them 2. Balantidium coli Trophozoite is characterized by the presence of: a. Both of Macro and micronuclei b. 4 pairs of Flagella c. Only one Macro Nucleus d. none of them 3. Balantidium coli is transmitted through: a. contaminated food and water b. sexual contact c. inhalation d. blood transfusion 4. The species of Plasmodium that infect Human are …………… a. Plasmodium falciparum b. Plasmodium vivax c. Plasmodium ovale d. Plasmodium malariae e. All of them 5. Alteration of Generation in Malaria life cycle refers to…… a.Has sexual stages in Human body b.That possesses sexual and asexual stage c.Has a sexual multiplication in insect d.none of them 6. The stages of Plasmodium life cycle in Human are:</p><p>5 a.Erythrocytic schizogony b.Exo- erythrocytic schizogony c. Sporogony d. Both a and b 7. The most commonly used drugs in plasmodium treatment are: a. Chloroquine b. Sulfadoxine-pyrimethamine (Fansidar) c. Flagyl d. Both a and b e. Both b and c 8. The definitive host of Toxoplasma gondii is….. a. Wild animals b. Cat c. Human d. All of them 9. Toxoplasma gondii infection may be acquired through: a. Ingestion of the sporulated Oocyst b. Transplacental transmission c.Blood transfusion d.All of them SAQ: 1. Clinical signs of Plasmodium falciparum infection 2. Laboratory diagnosis of Plasmodium infection in Human.</p><p>6</p>