<p>Supplemental material: Table 3 haplotype counts and odds ratios</p><p>Hypertension 2X2 risk or protective </p><p> haplotype vs. others C Haplotyp # in 1st SNP 2nd SNP # in Control OR h e Case Risk/protective Haplotype Case # Control #</p><p>GC 0 35 GC 0.5 35.5 47.5 2 rs10496288 rs10496289 AC 3543 5220 Other 3904.5 5841.5 GT 361 621 AA 33 2 AA 33 2 25.0 AG 3103 4676 other 3870 5869 2 rs13420028 rs10188442 CA 767 1193 CG 1 5 AC 62 15 AC 62 15 6.3 AG 2928 4400 other 3842 5858 5 rs7735940 rs12522034 CC 914 1458 CG 0 3 AA 1706 2615 GA 3 39 8.7 GA 3 39 other 3897 5837 5 rs6452524 rs6887846 GG 2191 3222 AG 4 0 AC 0 42 AC 0.5 42.5 56.9 6 rs3798440 rs9350602 AT 588 902 other 3904.5 5834.5 GC 3316 4932 120. CC 3174 4786 GC 39.5 0.5 1 8 rs2469997 rs6469823 GC 39 0 other 3865.5 5876.5 GT 691 1090 335. CC 2601 3923 CG 108.5 0.5 8 8 rs7827545 rs1372662 CG 108 0 other 3796.5 5875.5 TG 1195 1952 TC 0 1 GC 1318 1922 TC 3 47 10.5 1 TC 3 47 other 3899 5828 rs7960483 rs10785581 2 TG 2581 3906 GG 2 1 CA 3413 5208 TA 44 3 22.3 2 CG 12 18 other 3848 5855 rs200752 rs200759 0 TA 44 3 TG 435 647 *** No clear risk haplotype </p><p>Coronary Artery Disease 2X2 risk or protective </p><p> haplotype vs. others C Haplotyp # in 1st SNP 2nd SNP # in Control OR h e Case Risk/Protective Haplotype Case # Control #</p><p>CC 24 2 CC 24 2 18.4 1 rs12091564 rs10218795 CT 135 207 other 3828 5874 TC 3693 5667 CA 2 71 CA 2 71 23.5 CG 1545 2499 other 3847 5804 3 rs11924705 rs6789378 TA 2302 3305 TG 3 1 AG 3742 5728 GG 27.5 0.5 84.5 4 rs7697839 rs7673097 GG 27 0 other 3825.5 5876.5 GT 83 148 GC 2130 2777 GG 62 108 1.1 GG 62 108 other 3785 5761 9 rs1333048 rs1333049 TC 5 7 TG 1655 2984 CC 76 114 GT 19.5 0.5 59.8 CT 3701 5674 other 3833.5 5876.5 1 rs2066314 rs2066315 0 GC 56 88 *** No clear risk GT 19 0 haplotype 1 rs1165668 rs1165669 AC 2825 4339 GC 21.5 0.5 65.9 GC 21 0 other 3831.5 5875.5 2 GT 1006 1536 AT 0 1</p><p>Haplotype information and odds ratios (OR) information is given for those single nucleotide polymorphisms (SNPs)SNPs reported in the article. (Ch) denotes chromosome. The highlighted areas denote haplotypes not counted due to low counts. Except for two tables, after eliminating any haplotype that is rare in both cases and controls (always < 12 total), there is clearly only one haplotype that is risk or protective. The odds ratio was calculated as the odds for this haplotype divided by the odds for the other two haplotypes combined. If any cell in this fourfold table is zero, 0.5 was added to each cell.</p>