Ratnesh Kumar Soni K.N. Govt. P.G. College,Gyanpur Assistant Professor Gyanpur, (Bhadohi) Department of Zoology E-Mail: [email protected] Multiple Choice Questions M.Sc. Zoology IV Semester Special Paper III C ( Cell Biology), Ultrastructure and Morphodynamics of Cell 1. Average thickness of plasma membrane is 6. The main role of carbohydrates in the cell a. 5-10 nm membrane is b. 10-20 nm a. Adhesion c. 5-50 nm b. Recognition d. 50-100 nm c. Locomotion d. Reception 2. The fluidity of plasma membrane increase with 7. Glycolipids in plasma membrane are usually a. Increase in saturated fatty acids in the located at: membrane a. Outer leaflet of plasma membrane b. Increase in unsaturated fatty acids in the b. Inner leaflet of plasma membrane membrane c. Evenly distributed in both inner and c. Increase in unsaturated fatty acids in the outer leaves of plasma membrane membrane d. Cannot be predicted, it varies according d. Increase in glycolipid content in the to cell types membrane 8. Transverse diffusion (flip-flop) is the 3. Which of the following is NOT the function movement of of plasma membrane? a. Cholesterol molecule a. Intercellular interactions b. amino acid b. Responding to external stimuli c. Protein c. Energy transduction d. Phospholipid d. Assisting in chromosome segregation 9. Which of the following genetic diseases is 4. The carbohydrate content of plasma caused by mutations in a membrane protein? membrane in eukaryotes is: a. Alzheimer’s disease a. 2 – 10 % by weight b. Parkinson’s disease b. 20 – 25% by weight c. Anemia c. 30 – 50 % by weight d. Hemolytic anemia d. 60 – 70% by weight 10. The protruding invaginated sheets inside 5. Carbohydrates in the plasma membrane: mitochondria is known as a. Always face inward to the non-polar a. Cristae portion of membrane b. Fimbrae b. Always face outward to extracellular c. Hyphae space d. Cellular Digestion c. Always face to the lumen of cells d. Directed to all sides in the membrane 11. Which part of mitochondria has almost 70- random 75% protein content? a. Outer membrane b. Inner membrane c. Both outer and inner membrane d. Intermembrane space 19. Which type of endomembrane secretion occurs in nerve cells? 12. In the inner membrane of mitochondria, a. Constitutive there is one protein molecule for b. Regulatory approximately every c. Non-continuous a. 15 phospholipids d. Intermittent b. 5 phospholipids c. 25 phospholipids 20. Which of the following biomolecules are d. 50 phospholipids contained in the lysosomes? a. Nucleic acids 13. Cardiolipin present in inner mitochondrial b. Ribonucleic acids membrane plays a role in c. Proteins a. Formation of the respiratory d. Polysaccharides mechanisms b. Activation of proteins involved in 21. In animals, the amount of cholesterol Glycolysis present in cell membrane is c. Activation of proteins involved in a. 20% electron oxidation b. 15% d. Activation of proteins c. 50% d. 33% 14. Porins are present in a. Inner membrane 22. Carbohydrates present in cell membrane are b. Outer membrane generally c. Both inner and outer membrane a. Monosaccharides d. Intermembrane space b. Disachharides c. Oligosaccharides 15. Which of the following together represent an d. Polysaccharides endomembrane system? a. macromolecules of the cell 23. Which of the following is described by the b. Cell receptors fluid mosaic model c. Cytoplasmic structures a. Nucleus d. Nuclear structures b. Plasma membrane c. Endoplasmic reticulum 16. Proteins are synthesized in which of the d. Ribosome following organelle of the endomembrane system 24. Which of the following organelle control a. Endoplasmic reticulum intracellular digestion of macromolecules b. Golgi complex with the help of hydrolytic enzymes? c. Lysosomes a. Plastid d. Vacuoles b. Peroxisome c. Lysosome 17. There are ______ types of secretory d. Actin activities of a cell. a. One 25. Which of these are not the hydrolytic b. Two enzymes of lysosome? c. Three a. Lipases d. Four b. Sulfatases c. Phosphatases 18. In regulated secretion, materials are d. Aldolase a. Secreted b. Stored 26. Digestion of cell’s own component is known c. Degraded as d. Aggregated a. Autophagy b. Heterophagy a. Lysosomal aggregation c. Phagocytosis b. Multiple units of ribosomes d. Pinocytosis c. Attachment of many ribosomes to common mRNA 27. Which of the following organelle takes part d. Attachment of many mRNA to in the secretion? ribosomes a. Cytoplasm b. Ribosomes 35. Name the antibiotic which inhibits protein c. ER compartments synthesis in eukaryotes? d. Golgi apparatus a. Penicillin b. Cycloheximide 28. Which of the following is not the function of c. Cinhonine the Golgi apparatus? d. Chlorophenicol a. Processing and shorting of glycoprotein b. Lipid metabolism 36. Which of the following is NOT the type of c. Carbohydrate metabolism cancer? d. Amino acid metabolism a. Carcinomas b. Sarcomas 29. What is microsome? c. Leukemia a. Compartment of Golgi d. Caspases b. Smaller ribosomes c. Small ER compartments 37. What is the origin of the cancerous cells? d. Small vesicles of fragmented ER a. Monoclonal b. Polyclonal 30. Which of the following coated vesicle c. Stem cells transport protein from ER to Golgi? d. Mesodermal cells a. Clathrin b. COP II 38. Which of the following is the characteristic c. COP I of a cancer cell? d. COP III a. Density dependent inhibition b. Contact inhibition 31. Genetic information stored in mRNA is c. Loss of anchorage dependence translated to polypeptide by d. Apoptosis a. Ribosome b. Nucleus 39. If DNA is damaged, which of the following c. Endoplasmic reticulum gene arrest cell cycle? d. Golgi apparatus a. Rb b. p53 32. Which of the following Scientist discovered c. Hedgehog receptor ribosome for the first time? d. p16 a. George Emil Palade b. Theodor Schwann 40. Name the cells which lost their control of c. Antonie van Leeuwenhoek the regulated division, differentiation, and d. Robert Hook apoptosis? a. Tumor cell 33. Which of the following is not a sorting b. Immune cell signal present of protein c. Platelets a. Signal patch d. Stem cells b. Signal peptide c. Carbohydrate sequence 41. Chromosome is the thickest during d. Amino acid sequence a. Prophase b. Metaphase 34. Which of the following statement is defines c. Anaphase polysomes? d. Telophase c. Tubulin 42. The structure help in chromosome d. Actin and myosin separation during cell division are 50. Which of the following is a microtubule a. Microtubules associated protein (MAPS) b. Microfilaments a. ‘tus’ protein c. Intermediate filaments b. ‘tau’ protein d. All c. ‘rho’ protein d. G protein 43. The mitotic apparatus of animal cells comprises of 51. The microtubule assembly is inhibited by a. Kinetochore microtubules a. Colchicine b. Polar microtubules b. Vincristine c. Both c. Vinblastine d. None d. All of these 44. Which microtubule motor proteins 52. Chromosome movement during cell division conserved in all spindle fibre is regulated by a. BimC a. Microtubules b. CENP-E b. Microfilaments c. Cytosolic dynein c. Intermediate filaments d. All d. All of these 45. During cell division the (-) end of 53. Which of the following statements are true microtubule towards a. Intermediate filaments are resistant to a. Pole colchicine and cytochalasin-B b. Chromosome b. Microtubules are made up of tubulins c. Any side c. Microfilaments are made up of actin d. None d. All of these 46. Name the components participate in 54. Cilia and flagella of Eukaryotic cells are attaching chromosomes to microtubules made up of during cell division a. Keratin a. Centromere b. Tubulin b. Kinetochore c. Lamin c. Spindle proteins d. Desmi d. All 55. Which of the following is the most 47. Which of the following cells lacks heterogeneous type of cytoskeletal filament cytoskeleton? a. Microtubules a. Eukaryotic plant cell b. Microfilaments b. prokaryotic bacterial cells c. Intermediate filaments c. Bot A and B d. None of these d. Prokaryotic cells and eukaryotic animal cells 56. Microfilaments are involved in a. Cyclosis 48. Cytoskeletons are chemically b. Amoeboid movement a. Nucleoprotein filaments c. Furrow formation during cell division b. Nucleoprotein filaments and lipids d. All c. Ribonucleoproteins filaments d. Protein Filament 57. Which of the following is a microtubule organizing center? 49. Microtubules are made up of a. Centrosome a. Flagellin b. Kinetochore b. Desmin c. G2 phase d. Centrioles 58. Name the protein which holds two sister 66. Polyploidy can be artificially induced by chromatids? a. Self pollination a. Securin b. Line breeding b. Separase c. Inbreeding c. Cohesin d. Colchicine d. APC 67. Chiasmata formation takes place during 59. Which of the following microtubule pulls a. Prophase I the chromosomes towards pole? b. Metaphase I a. Astral c. Anaphase I b. Polar d. Telophase I c. Kinetochore d. Centrioles 68. Anaphase is brought about by the change in which cytoskeletal element? 60. Spindle fiber attached to the chromosome by a. Tubulin a process known as_________ b. Actin a. Congression c. Myosin b. Binding d. Dyani c. Alignment d. Search and capture 69. Chromosomal compaction is brought about by 61. What is congression? a. Cohesin a. Attachment of microtubule to b. Thrombin chromosomes c. Condensin b. Attachment of two sister chromatids d. Sequrin c. The endpoint of the spindle pole d. The midpoint of two spindle poles 70. P53 activates transcription of a. P5 62. Which of these proteins is responsible for b. p27 depolymerization of microtubule? c. p21 a. Kin I kinesin d. p35 b. CENP-E c. Dynein 71. Name the cells which lost their control of d. Actin the regulated division, differentiation, and apoptosis? 63. Name the medication which hinders the a. Tumor cell shortening of the microtubule. b. Immune cell a. Colchicine c. Platelets b. Cytochalasin d. Stem cells c.