Index -acylation 365 , -unsaturated esters -alkoxymethylenation 364–5 enantioselective synthesis 544 -alkylation formation and reactions of 591–6 of [14C]malonates 359–62 from alkoxycarbonyl[14C]methylenezinc of alkyl [14C]cyanoacetates 422 bromide 335–6 -amino acids, exchange labeling 58, 94–5 from alkyl 2-trimethylsilyl[14C]- -amino acids acetates 329 by enantioselective catalytic from [14C]malonates 265–7, 354, 357 tritiation 530–4 from trialkyl phosphono[14C]acetates 218, by enantioselective tritioreduction of 322–8, 544 oximes 540 , -unsaturated ketones, exchange from 2-acetamido-2-cyano[2-14C]- labeling 87 acetate 427 , -unsaturated oximes, exchange from [14C]glycines 316–7 labeling 87 from [2-14C]malonates 371–2 , -unsaturated ketones 542–4 -arylation absorption see ADME studies of [14C]malonates 362–4 [14C]acarbose, by biotransformation 623 of alkyl [14C]cyanoacetates 422 accelerator mass spectrometry (AMS) 1 [3H]- -conotoxin G1 95 [14C]acetaldehyde 290, 445–6 , -dehydrogenation/tritioreduction of [14C]acetamidines 377–8 carbonyls 483–5 2-acetamido[2-14C]acetate, from [14C]- , -unsaturated acids, exchange labeling 76 cyanoacetic acid 427 , -unsaturated acids see also , -unsaturated acetanilide derivatives, exchange labeling 80 esters [2H,3H]acetic acid (chiral) 617 from [14C]cyanohydrins 406–7 [14C]acetic acids from [14C]malonates by Knoevenagel [14C]acetic anhydride and mixed anhydrides reaction 365–7 from 298–301 , -unsaturated [14C]aldehydesCOPYRIGHTED 312 [14C]acetoacetates MATERIAL from 346–8 , -unsaturated amino acids [14C]acetyl halides from 289–90 N-acetyl, enantioselective reduction 532–4 chiral acetate 617 N-acetyl, preparation 530–2 esterification 301–2 reconstitution strategies 530–4 formation of 269, 287–9, 446–7 , -unsaturated carbonyls 503–5 -halogenation of 308 , -unsaturated [14C]carboxamides 323, 327 in C-[14C]acetylations 291–6 Preparation of Compounds Labeled with Tritium and Carbon-14 Rolf Voges, J.