Chemical and Pharmaceutical Bulletin Published by the Pharmaceutical Society of Japan Editorial Board Chairman of Committee Naoto Oku [School of Pharmaceutical Sciences, University of Shizuoka] Editors-in-Chief Chem. Pharm. Bull.: Yoshiji Takemoto [Graduate School of Pharmaceutical Sciences, Kyoto University] Biol. Pharm. Bull.: Ken-ichi Hosoya [Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama] Yakugaku Zasshi: Tadashi Suzuki [Graduate School of Pharmaceutical Sciences, Nagoya City University] Section Editors-in-Chief Masami Ishibashi [Graduate School of Pharmaceutical Sciences, Chiba University] Hiroyuki Itabe [School of Pharmacy, Showa University] Hiroshi Katsuki [Faculty of Life Sciences, Kumamoto University] Sumio Ohtsuki [Faculty of Life Sciences, Kumamoto University] Tetsuya Ozeki [Graduate School of Pharmaceutical Sciences, Nagoya City University] Masahiko Satoh [School of Pharmacy, Aichi Gakuin University] Editors Yoshiaki Amakura [College of Pharmaceutical Sciences, Matsuyama University] Yoshiharu Deguchi [Faculty of Pharma Sciences, Teikyo University] Hirotoshi Echizen [Faculty of Pharmaceutical Sciences, Meiji Pharmaceutical University] Yasuyuki Fujiwara [School of Pharmacy, Tokyo University of Pharmacy and Life Sciences] Yukihiro Goda [National Institute of Health Sciences] Takashi Hakamatsuka [National Institute of Health Sciences] Yoshitaka Hamashima [School of Pharmaceutical Sciences, University of Shizuoka] Shuntaro Hara [School of Pharmacy, Showa University] Noriyuki Hatae [School of Pharmaceutical Sciences, Health Sciences University of Hokkaido] Masamichi Hirose [Faculty of Pharmaceutical Sciences, Iwate Medical University] Hiroaki Hisa [Faculty of Pharmaceutical Sciences, Kyusyu University of Health and Welfare] Shin-ichi Hoshino [Graduate School of Pharmaceutical Sciences, Nagoya City University] Tsuyoshi Ikeda [Faculty of Pharmaceutical Sciences, Sojo University] Hirotaka Imai [School of Pharmaceutical Sciences, Kitasato University] Yasushi Ishihama [Graduate School of Pharmaceutical Sciences, Kyoto University] Yuji Ishii [Graduate School of Pharmaceutical Sciences, Kyushu University] Shigeru Itai [School of Pharmaceutical Sciences, University of Shizuoka] Kiyoshi Ito [Faculty of Pharmaceutical Sciences, Setsunan University] Kousei Ito [Graduate School of Pharmaceutical Sciences, Chiba University] Keiji Izushi [School of Pharmacy, Shujitsu University] Toshiyuki Kan [School of Pharmaceutical Sciences, University of Shizuoka] Yoshiki Kashiwada [Institute of Biomedical Sciences, Tokushima University Graduate School] Shigeru Kawakami [Graduate School of Biomedical Sciences, Nagasaki University] Kiyoshi Kawasaki [Faculty of Pharmaceutical Sciences, Doshisha Women’s College of Liberal Arts] Hiroto Kawashima [Graduate School of Pharmaceutical Sciences, Chiba University] Tomoki Kimura [Faculty of Science and Engineering, Setsunan University] Ken-Ichi Kiyomiya [School of Pharmacy, Hyogo University of Health Sciences] Michiya Kobayashi [School of Pharmaceutical Sciences, Health Sciences University of Hokkaido] Tsuneo Kobayashi [School of Pharmacy and Pharmaceutical Sciences, Hoshi University] Munetaka Kunishima [Institute of Medical, Pharmaceutical, and Health Sciences, Kanazawa University] Nariyasu Mano [Department of Pharmaceutical Sciences, Tohoku University Hospital] Toshiyuki Masuzawa [Faculty of Pharmacy, Chiba Institute of Science] Kinzo Matsumoto [Institute of Natural Medicine, University of Toyama] Katsuyoshi Matsunami [Graduate School of Biomedical & Health Sciences, Hiroshima University] Tsuyoshi Miura [School of Pharmacy, Tokyo University of Pharmacy and Life Sciences] Kunikazu Moribe [Graduate School of Pharmaceutical Sciences, Chiba University] Toshio Morikawa [Pharmaceutical Research and Technology Institute, Kinki University] Tatsuya Morimoto [School of Pharmaceutical Sciences, University of Shizuoka] Hiroyuki Morita [Institute of Natural Medicine, University of Toyama] Takeshi Nabe [Faculty of Pharmaceutical Sciences, Setsunan University] Masayuki Nadai [Faculty of Pharmacy, Meijo University] Hideko Nagasawa [Faculty of Pharmaceutical Sciences, Gifu Pharmaceutical University] Akito Nagatsu [College of Pharmacy, Kinjo Gakuin University] Makoto Nakajima [Graduate School of Pharmaceutical Sciences, Kumamoto University] Tsuyoshi Nakanishi [Faculty of Pharmaceutical Sciences, Gifu Pharmaceutical University] Mikiro Nakashima [Graduate School of Biomedical Sciences, Nagasaki University] Hiroyuki Nishi [Faculty of Pharmacy, Yasuda Women’s University] Mitsuhiko Nose [Faculty of Pharmacy, Meijo University] Hiroaki Ohno [Graduate School of Pharmaceutical Sciences, Kyoto University] Susumu Ohya [Kyoto Pharmaceutical University] Kazuhiko Oishi [Faculty of Pharmaceutical Sciences, Meiji Pharmaceutical University] Shigehiro Osada [Graduate School of Pharmaceutical Sciences, Nagoya City University] Masayoshi Oyama [Faculty of Pharmaceutical Sciences, Gifu Pharmaceutical University] Yutaka Sadakane [Faculty of Pharmaceutical Sciences, Suzuka University of Medical Science] Hideyuki Saito [Department of Pharmacy, Kumamoto University Hospital] Hiroyuki Saito [Institute of Biomedical Sciences, Tokushima University Graduate School] Daisuke Sawada [Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama University] Masayuki Seki [Tohoku Pharmaceutical University] Toshiaki Sendo [Department of Pharmacy, Okayama University Hospital] Mitsuru Sugawara [Faculty of Pharmaceutical Sciences, Hokkaido University] Takumichi Sugihara [Faculty of Pharmaceutical Sciences, Niigata University of Pharmacy and Applied Life Sciences] Daigo Sumi [Faculty of Pharmaceutical Sciences, Tokushima Bunri University] Takaaki Sumiyoshi [Fuculty of Chemistry, Materials and Bioengineering, Kansai University] Shinya Suzuki [Faculty of Pharmaceutical Sciences, Tokushima Bunri University] Atsushi Takeda [School of Pharmaceutical Sciences, University of Shizuoka] Mariko Takeda [Faculty of Pharmaceutical Sciences, Kobe Gakuin University] Yoshio Tanaka [Faculty of Pharmaceutical Sciences, Toho University] Toshiko Tanaka-Kagawa [Yokohama University of Pharmacy] Koichi Tan-no [Tohoku Pharmaceutical University] Yoshikazu Tasaki [Department of Hospital Pharmacy and Pharmacology, Asahikawa Medical University] Tomohiro Terada [Department of Pharmacy, Shiga University of Medical Science Hospital] Hidetoshi Tokuyama [Graduate School of Pharmaceutical Sciences, Tohoku University] Yuichi Tozuka [Faculty of Pharmaceutical Sciences, Osaka University of Pharmaceutical Sciences] Seiji Tsuboi [School of Pharmacy, Shujitsu University] Takashi Uehara [Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama University] Akemi Umeyama [Faculty of Pharmaceutical Sciences, Tokushima Bunri University] Hiromitsu Yamamoto [School of Pharmacy, Aichi Gakuin University] Etsuo Yonemochi [School of Pharmacy and Pharmaceutical Sciences, Hoshi University] Hideyuki Yoshida [Faculty of Pharmaceutical Sciences, Fukuoka University] Makoto Yoshida [Faculty of Pharmacy, Takasaki University of Health and Welfare] Kouichi Yoshinari [School of Pharmaceutical Sciences, University of Shizuoka] Leslie Z. Benet [University of California, U.S.A.] Henri B. Kagan [University Paris-Sud, France] Manfred Schubert-Zsilavecz [Johann Wolfgang Goethe University, Germany] Mukund P. Sibi [North Dakota State University, U.S.A.] Amos B. Smith, III [University of Pennsylvania, U.S.A.].