ESSENTIAL DRUGS LIST ﺃ- ﺍﻻﺴﺒﻘﻴﺔ ﺍﻻﻭﻟﻰ (priority 1):- ﻭﺘﺸﺘﻤل ﻋﻠﻰ ﻤﺠﺎﻤﻴﻊ ﺍﻻﺩﻭﻴﺔ ﺍﻟﻀﺭﻭﺭﻴﺔ ﺍﻟﻤﻌﺭﻭﻓﺔ ﺒﺎﻟﻔﻌﺎﻟﻴﺔ ﺍﻟﻌﺎﻟﻴﺔ ﻭﺴﻼﻤﺔ ﺍﺴﺘﻌﻤﺎﻟﻬﺎ ﻭﺘﻘﺴﻡ ﺍﻟﻰ:- A ---- Drugs of First choice ﺍ ﻭ ﻻﹰ:- ﻤﺠﻤﻭﻋﺔ ﺍﺩﻭﻴﺔ ﺍﻻﺨﺘﻴﺎﺭ ﺍﻻﻭل ﻭﻤﺅﺸﺭ A/a ---- Alternative drugs ﺜ ﺎ ﻨ ﻴ ﺎﹰ:- ﻤﺠﻤﻭﻋﺔ ﺍﺩﻭﻴﺔ ﺍﻻﺨﺘﻴـﺎﺭ ﺍﻻ ﻭل ﻤـﻥ ﺍﻟﺒـﺩﺍﺌل ﻤـﻥ ﻨﻔـﺱ ﺍﻟﻤﺠﻤﻭﻋﺔ A/L---- Essential but of limited use ﺜ ﺎ ﻟ ﺜ ﺎﹰ:- ﻤﺠﻤﻭﻋﺔ ﺍﺩﻭﻴﺔ ﺍﻟﺨﻁ ﺍﻻﻭل ﻤﺤﺩﻭﺩﺓ ﺍﻻﺴﺘﻌﻤﺎل This category represent the most necessary drugs that should be regularly available in adequet quantities to satisfy the needs of the majority of Iraqi people and should be of a good quality to ensure safety and efficacy. ﺏ- ﺍﻻﺴﺒﻘﻴﺔ ﺍﻟﺜﺎﻨﻴﺔ (priority 2):- ﻭﺘﺸﺘﻤل ﻋﻠﻰ ﺍﻻﺩﻭﻴﺔ ﺍﻟﻤﻌﺭﻭﻓﺔ ﺒﻔﻌﺎﻟﻴﺘﻬﺎ ﺍﻟﻌﺎﻟﻴﺔ ﻭﺴﻼﻤﺔ ﺍﻻﺴﺘﻌﻤﺎل ﻤﻊ ﺨﺼﺎﺌﺹ ﻭﻤﻭﺍﺼﻔﺎﺕ ﺍﻀﺎﻓﻴﺔ ﻭﻟﻜﻨﻬﺎ ﺒﺎﻫﻀﺔ ﺍﻟﺜﻤﻥ ﻟﺫ ﻟﻙ ﺘﻭﻓﺭ ﺤ ﺎ ﻟ ﻴ ﺎﹰ ﺒﻜﻤﻴﺎﺕ ﻤﺤـﺩﻭﺩﺓ ﻭﺘـﻭﺯﻉ ﻋﻠﻰ ﺍﻟﻤﺭﺍﻜﺯ ﺍﻟﺘﺨﺼﺼﻴﺔ ﺍﻭ ﺘﻭﺼﻑ ﻟﻠﻤﺭﻴﺽ ﺍﻟﺫﻱ ﻟﻡ ﻴﺴﺘﺠﺏ ﻻﺩﻭﻴﺔ ﺍﻻﺴﺒﻘﻴﺔ ﺍﻻﻭﻟـﻰ ﺍﻭ ﻟﻌـﺩﻡ ﻤﻼﺌﻤﺘﻬﺎ ﺒﺴﺒﺏ ﺍﻻﺜﺎﺭ ﺍﻟﺠﺎﻨﺒﻴﺔ ﺍﻭ ﻟﻠﺤﺎﻻﺕ ﺍﻟﻤﺭﻀﻴﺔ ﺍﻟﻤﺼﺤﻭﺒﺔ ﺒﺎﻻﺨﺘﻼﻁـﺎﺕ ﺍﻟﻤﻌﻘـﺩﺓ ، ﻭﺘﻘـﺴﻡ ﻭﺘﺅﺸﺭ ﻫﺫﻩ ﺍﻻﺴﺒﻘﻴﺔ ﻜﻤﺎ ﻓﻲ (ﺃ) : B ---- First choice ﺃ ﻭ ﻻﹰ:- ﺩﻭﺍﺀ ﺍﻟﺨﻴﺎﺭ ﺍﻻﻭل B/a ---- Alternative ﺜ ﺎ ﻨ ﻴ ﺎﹰ:- ﺩﻭﺍﺀ ﺍﻟﺨﻴﺎﺭ ﺍﻻﻭل ﻤﻥ ﺍﻟﺒﺩﺍﺌل ﻤﻥ ﻨﻔﺱ ﺍﻟﻤﺠﻤﻭﻋﺔ B/L ---- Limited use ﺜ ﺎ ﻟ ﺜ ﺎﹰ:- ﺩﻭﺍﺀ ﺍﻟﺨﻴﺎﺭ ﺍﻻﻭل ﻤﺤﺩﻭﺩ ﺍﻻﺴﺘﻌﻤﺎل ﺠـ- ﺍﻻﺴﺒﻘﻴﺔ ﺍﻟﺜﺎﻟﺜﺔ (priority 3):- ﻭﺘﺸﻤل ﺍﻻﺩﻭﻴﺔ ﺍﻟﻤﻜﻤﻠﺔ ﺍﻟﻤﺘﺒﻘﻴـﺔ ﻤـﻥ ﻗﺎﺌﻤـﺔ ﺍﻻ ﺩﻭﻴـﺔ ﺍﻻﺴﺎﺴـﻴﺔ Complimantary drugs ﻭﺘﺅﺸﺭ ﻜﻤﺎ ﻴﻠﻲ:- C ---- ﺃ ﻭ ﻻﹰ:- ﺍﺩﻭﻴﺔ ﺍﻟﺨﻴﺎﺭ ﺍﻻﻭل ﻤﻥ ﺍﻻﺴﺒﻘﻴﺔ ﺍﻟﺜﺎﻟﺜﺔ C/a ---- Alternative ﺜ ﺎ ﻨ ﻴ ﺎﹰ:- ﺍﺩﻭﻴﺔ ﺍﻟﺨﻴﺎﺭ ﺍﻻﻭل ﻤﻥ ﺍﻟﺒﺩﺍﺌل ﻤﻥ ﺍﻻﺴﺒﻘﻴﺔ ﺍﻟﺜﺎﻟﺜﺔ C/L ---- Limited use ﺜ ﺎ ﻟ ﺜ ﺎﹰ:- ﺍﺩﻭﻴﺔ ﺍﻟﺨﻴﺎﺭ ﺍﻻﻭل ﻤﺤﺩﻭﺩ ﺍﻻﺴﺘﻌﻤﺎل ﻤﻥ ﺍﺩﻭﻴﺔ ﺍﻻﺴﺒﻘﻴﺔ ﺍﻟﺜﺎﻟﺜﺔ ﻟﺴﻬﻭﻟﺔ ﺍﻟﺘﻭﻀﻴﺢ:- A : Drugs of first choice (Reasonable cost). A/a: First choice alternative drugs. A/L: First choice drugs of limited use. B: First choice drugs (Best & expensive) B/a: First choice alternative drugs. B/L: First choice drugs of limited use. C: Complementary drugs. Decision : All human products must be of human recombinant origin wherever these are avialable in the markets. : For oral solution it is preferable: Syrup then Suspension and then Elixir : Caution To be written if the products contian metabisulphite as following (Caution: this product contain metabisulphite – may cause broncho spasm in atopic & Asthmatic subjects) : There is no objection of all tablets that approved in the national list as scored tab to be plain tab (Not scored) ESSENTIAL DRUGS LIST & THE MOST NECESSARY DRUGS 1 CARDIOVASCULAR SYSTEM 1 A Positive inotropic drugs 1 Aa Digitalis glycoside B Digoxin tab 125 mcg A Digoxin scored tab 250 mcg A Digoxin PG Elixir 50mcg /ml (60ml) A Digoxin inj 250 mcg/ml, ( 2ml Amp) 1 A.b Phosphodiesterase inhibitors: A/L Enoximone inj:5mg/ml (20ml Amp) Only For heart specilised centers – See section 17 1 B Diuretics A/L Bumetanide tab 1 mg B Chlorthalidone tab 50mg A Frusemide I.V. , I.M. inj 20mg/2ml Amp A Frusemide I.V. infusion inj 10mg/ml, ( 25ml - Amp) A Frusemide tab 40mg A Frusemide oral solution pead. Liquid 1mg/1ml A Frusemide oral solution 4mg/ml A Hydrochlorothiazide tab 25mg A Hydrochlorothiazide tab scored 50mg B/L Indapamide tab 2.5mg A Mannitol 10% I.V. infusion 500ml A Mannitol 20% I.V. infusion 500ml B/L Metolazone tab 5mg A Spironolactone tab 25mg Spironolactone tab 50mg (558) A Spironolactone tab 100mg 1 C Beta adrenoceptor blocking drugs A Atenolol tab 100mg A Atenolol tab (or scored tab) 50mg A Atenolol inj 500mcg/ml (10ml Amp) A/L/a Bisoprolol fumarate scored tab 5mg A/L Carvedilol 3.125mg tab A/L Carvedilol 6.25mg tab A/L Carvedilol 25mg tab 1 اﻟﻬﻴﺌﺔ اﻟﻮﻃﻨﻴﺔ ﻻﻧﺘﻘﺎء اﻻدوﻳﺔ National Board For Selection Of The Drugs/ NBSD B/L Esmolol Hcl I.V. infusion 10mg /ml (10ml vial) (CCU) A/L Labetalol inj 5mg/ml, (20ml Amp) B/L Labetalol tab 200mg A/a Metoprolol tartrate tab 50mg A/a Metoprolol tartrate 100mg tab A/a Metoprolol tartrate I.V. inj. 1mg /1ml (5ml Amp) C/L Pindolol tab 5mg A/L Propranolol Hcl slow I.V. inj 1mg/ml (1ml -Amp) A Propranolol Hcl tab 10mg A Propranolol Hcl tab (or scord tab) 40mg 1 D Anti arrhythmic drugs A Adenosine inj. 3mg/ml (2ml – vial) or amp. A/L Amiodarone Hcl inj 50mg/ml ( 3ml - Amp) A Amiodarone Hcl tab 200mg A/L Disopyramide caps 100mg B/L Disopyramide tab Retard (s/r) 250mg A/L Disopyramide inj 10mg/ml (5ml- Amp) (Hospital only) A/L Flecainide acetate 50mg Tab. (Only in the heart specialised center) A/L Flecainide acetate inj 10mg/ ml (15ml-amp) (Only in the heart specialized center) A Lignocaine Hcl 2% 20mg /ml 2ml – amp ( CCU) A/L Mexiletine Hcl caps 200mg A/L Mexiletine Hcl I.V., I.V. infusion inj 25mg/ml, (10ml Amp) A/L/a Procainamide Hcl slow I.V., I.V. infusion inj 100mg/ml, (10ml vial) A/L/a Procainamide Hcl tab 500mg A Propafenon Hcl tab 150mg C Quinidine sulphate tab 200mg A Verapamil Hcl inj 2.5mg/ml, (2ml Amp) A Verapamil Hcl tab 40mg A Verapamil Hcl tab 80mg 1 E Anti - hypertensive drugs Note:- Principles for ARBs group (Angioteusin II Receptor blockers) To be available & dispensed limitly for the following cases only:- 1- Mild to moderately severe heart failure. 2- Diabetic (Type I & type II) Nephropathy with or with out hypertension (H.T) i-e D.M. concomitant with H.T or with out, that effecting on kidney’s function by the following evidences: a- Micro & macro albumin urea. b- Reduced GFR. c- Elevated serum creatinin. 3- Hypertension with proteinuria. When ACE-Is not tolerated by patient (e.g: side effects) Such as coughing/ or decrement in anti- proteinuric activity of ACEIs in those patients. Provided that (ARBs) to be dispensed by aspecialist or consultant in internal medicine , documented by report of scientific proofs & tests which referring to those above mentioned cases (a, b, c). There fore, ARBs as agroup of ACEIs not given or used by pregnant wowen at all. A Captopril tab 25mg A Captopril tab 50mg A Candesartan cilexetil scored tab 8mg (can be imported if irbesartan ,telmisartan, valsartan , Losartan are not avialable) (566) A Candesartan cilexetil 16mg tab (can be imported if irbesartan ,telmisartan, valsartan , Losartan are not avialable) (566) A/a Doxazosin mesylate equivalent to doxazosine 2mg scored tab A/a Enalapril maleate scored tab 5mg 2 اﻟﻬﻴﺌﺔ اﻟﻮﻃﻨﻴﺔ ﻻﻧﺘﻘﺎء اﻻدوﻳﺔ National Board For Selection Of The Drugs/ NBSD A/a Enalapril maleate scored tab 10mg A/a Enalapril maleate scored tab 20mg A/L Hydralazine Hcl I.V. Infusion inj 20mg per Amp. B Hydralazine Hcl tab 25mg (limited use) A Irbesartan 150mg tab (can be imported if candesartan ,telmisartan, valsartan , Losartan are not avialable) (566) A Irbesartan 300mg tab (can be imported if candesartan , valsartan , Losartan are not avialable) (566) A/a Lisinopril (Lisinopril (as base) or Lisinopril (anhydrous) , Lisinopril (as dihydrate) , the same drug with or without water of hydration) tab 10mg A/a Lisinopril (Lisinopril (as base) or Lisinopril (anhydrous) , Lisinopril (as dihydrate) , the same drug with or without water of hydration) tab 20mg A Losartan potassium tab 50mg (can be imported if, candesartan , irbesartan,telmisartan, valsartan are not avialable) A/L Methyldopate inj 50mg/ml (5ml Amp) (limited use) A Methyldopa tab 250mg B/L Minoxidil tab 5mg (limited) A/L Phenoxybenzamine Hcl caps 10mg A/L Phentolamine mesylate inj 10mg/ml (1ml Amp) C Prazosin Hcl tab or scord tab 1mg A/L Ramipril 2.5 mg tab. (598) A/L Ramipril 5 mg tab. (598) A/L Ramipril 10 mg tab. (598) A/L Sodium nitroprusside I.V. infusion 50mg Amp or vial with solvent A Terazosin as Hcl tab 2mg A Terazosin as Hcl tab 5mg A/L Tolazoline Hcl inj I.V. (limited use for cardiac surgery) A/a Telmisartan Tab 40mg (can be imported if, irbesartan, candesartan , valsartan , Losartan are not avialable) (566) A/a Telmisartan Tab 80mg (can be imported if , irbesartan , candesartan , valsartan , Losartan are not avialable) (566) A Valsartan tab or cap 80mg (can be imported if , irbesartan , candesartan , Losartan, telmisartan are not avialable) (678) A Valsartan tab or cap 160mg (can be imported if , irbesartan , candesartan , Losartan, telmisartan are not avialable) (678) 1 F Vasodilators A/a Amlodipine (as besylate) tab 2.5mg A/a Amlodipine (as besylate) scored tab 5mg or Cap. A Diltiazem HCl tab or cap 60mg (normal release) A Diltiazem HCl tab or cap (s/r) 90mg B Diltiazem HCl tab or cap (s/r) 120mg B Diltiazem HCl I.V inj or infusion 25mg/vial A Glyceryl trinitrate ( sublingual) tab 0.5mg A/L Glyceryl trinitrate inj 5mg/1ml Amp (5 ml-Amp) B Glyceryl trinitrate Patches 10mg B Glyceryl trinitrate Patches 5mg B Glyceryl trinitrate Patches 25mg A Isosorbide dinitrate tab (s/l i-e sublingual)5mg A Isosorbide dinitrate tab 10mg B Isosorbide dinitrate tab (s/r) 20mg or retard cap 20mg A/a Isosorbide mononitrate tab 10mg A Nifedipine (s/r) caps or tab. 10mg (40% of the need) A Nifedipine cap or tab (s/r or retard) 20mg (60% of the need) A/L Nimodipine tab 30mg 3 اﻟﻬﻴﺌﺔ اﻟﻮﻃﻨﻴﺔ ﻻﻧﺘﻘﺎء اﻻدوﻳﺔ National Board For Selection Of The Drugs/ NBSD A/L Nimodipine I.V. infusion 200mcg/ml (50ml vial) B Oxpentifylline tab 400mg (Pentoxifylline) 1 G Sympathomimetic drugs A Dobutamine (as Hcl) I.V infusion inj 250mg/amp or vial (12.5mg/ml 20ml amp or vial). A Dopamine Hcl inj 40mg/ml, (5ml Amp) A/L Ephedrine Hcl inj 3% 30 mg / ml,( 1ml Amp) ( hypotension prevention in epidural/spinal anaesthesia) A/a Ephedrine Hcl inj 3mg / ml, 10 ml Amp A/L Metaraminol (as tartrate) inj 10mg/ml, (1ml Amp) A/L Phenylephrine Hcl inj 10mg/ml, (1ml Amp) By s.c.