Annotated Bibliography of NIMR (Publications: 2011-2015) NIMR Library Annotated Bibliography of National Institute of Malaria Research (Publications: 2011-2015) Compiled and Edited by Md. Rashid Perwez Assistant Library and Information Officer Library and Information Centre ICMR-National Institute of Malaria Research Sector-8, Dwarka, New Delhi-110077 Email: [email protected]; Website: https://nimr.icmr.org.in Annotated Bibliography of NIMR (Publications: 2011-2015) NIMR Library Annotated Bibliography of National Institute of Malaria Research Publications (2011-2015) Contents Page no. Master List-Titles: A-Z 1. Titles: A-Z- 2011 1 2. Titles: A-Z- 2012 58 3. Titles: A-Z- 2013 99 4. Titles: A-Z- 2014 138 5. Titles: A-Z- 2015 177 6. Books: A-Z- 2011-2015 217 Index 7. NIMR Author(s): A-Z 224 8. Sources(s): A-Z 233 9. Publisher(s): A-Z 240 Annotated Bibliography of NIMR (Publications: 2011-2015) NIMR Library Master List Titles: A-Z 2011 1. Mathur A, Singh R, Yousuf S, Bhardwaj A, Verma SK, Babu P, Gupta V, Prasad GBKS, Dua VK. Antifungal activity of some plant extracts against clinical pathogens. Adv Appl Sci Res 2011; 2(2): 260-4. ABSTRACT The antifungal activity and minimum inhibitory concentration (MIC) of various plant extracts in different solvents such as hydro-alcohol (50 % v/v) and hexane of plants traditionally used as medicines as Valeriana jatamansi (Sugandhbala), Coleus barbatus (Pathar choor), Berberis aristata (Kingore), Asparagus racemosus (Satrawal), Andrographis paniculata (Kalmegha), Achyranthes aspera (Latjiri), Tinospora cordifolia (Giloei), Plantago depressa (Isabgol) were evaluated against Aspergillus niger and Candida albicans. Hydro-alcoholic extracts of all the plants were found to have maximum antifungal activity in comparison to hexane extracts. Hydroalcoholic extracts of Andrographis paniculata and Achyranthes aspera showed maximum potency against Aspergillus niger and Candida albicans at highest MIC value of 0.5 and 0.3 mg/ml respectively. Hexane extracts of Andrographis paniculata showed highest MIC value of 0.7 mg/ml against Aspergillus niger. KEY WORDS: Hydroalcoholic extracts, hexane extracts, clinical pathogens, antifungal activity. 2. Prajapati SK, Joshi H, Dua VK. Antigeneic repertoire of Plasmodium vivax transmission blocking vaccine candidates from the Indian subcontinent. Malar J 2011; 10: 111. ABSTRACT Background: Genetic polymorphism is an inevitable component of a multistage infectious organism, such as the malaria parasite. By means of genetic polymorphism, parasite opts 1 Annotated Bibliography of NIMR (Publications: 2011-2015) NIMR Library particular polymorph and reveals survival advantage. Pvs25 and pvs28 are sexual stage antigen genes, expressed at the ookinete stage inside the mosquito gut, and considered as potential transmission-blocking vaccine candidates. This study presents sequence variations in two important transmission blocking antigen genes pvs25 and pvs28 in the field isolates of P. vivax from the Indian subcontinent. Methods: One hundred microscopically diagnosed P. vivax isolates were collected from five geographical regions of India. Pvs25 and pvs28 genes were PCR amplified and sequenced to assess sequence variation among field isolates. Results: A total of 26 amino acid substitutions were observed in Pvs25 (10) and Pvs28 (16) among field isolates of P. vivax. Tandem repeat polymorphism observed in pvs28 shows 3-6 tandem repeats in the field isolates. Seven and eight novel amino acid substitutions were observed in Pvs25 and Pvs28, respectively in Indian isolates. Comparison of amino acid substitutions suggests that majority of substitutions observed in global isolates were also present in Indian subcontinent. A single haplotype was observed to be major haplotype among isolates of Delhi, Nadiad, Chennai and Panna except in isolates of Kamrup. Further, population comparison analyses suggest that P. vivax isolates inhabiting in north-eastern region (Kamrup) were distantly related with the isolates from remaining parts of the country. Majority of the amino acid substitutions observed in Indian isolates were more identical to the substitutions reported from isolates of Thailand and Bangladesh. Conclusion: Study uncovered many new amino acid substitutions as well as a predominance of single haplotype in Indian subcontinent except in north-eastern region of the country. The amino acid substitutions data generated in this study from different geographical regions of the Indian subcontinent could be helpful in designing a more effective anti-malarial transmission-blocking vaccine. 3. Verma G, Dua VK, Agarwal DD, Atul PK. Antimalarial activity of Holarrhena anti- dysenterica and Viola canesxcens, plants traditionally used against malaria in the Garhwal region of northwest Himalaya. Malar J 2011; 10: 20. ABSTRACT Background: The increasing number of multidrug-resistant Plasmodium strains warrants exploration of new anti-malarials. Medicinal plant research has become more important, particularly after the development of Chinese anti-malarial drug artemisnin from Artemisia annua. 2 Annotated Bibliography of NIMR (Publications: 2011-2015) NIMR Library The present study shows evaluation of anti-malarial effects of two plants commonly used against malaria in the Garhwal region of north-west Himalaya, in order to discover the herbal-based medicine. Methods: In vitro anti-plasmodial sensitivity of plant extracts was assessed using schizont maturation and parasite lactate dehydrogenase (pLDH) assay. Cytotoxic activities of the examined extracts were determined on L-6 cells of rat skeletal muscle myoblast. The 4-day test for anti-malarial activity against a chloroquine sensitivePlasmodium berghei NK65 strain in Swiss albino mice was used for monitoring in vivo activity of plant extracts. Results: Chloroform extract of H. antidysenterica (HA-2) and petroleum ether extract of V. canescens (VC-1) plants significantly reduced parasitaemia in P. berghei infected mice. The extract HA-2 showedin vitro anti-plasmodial activity with its IC50 value 5.5 μg/ml using pLDH assay and ED50 value 18.29 mg/kg in P. berghei infected Swiss albino mice. Similarly petroleum ether extract of V. canescens(VC-1) showed in vitro anti-plasmodial activity with its IC50 value 2.76 μg/ml using pLDH assay and ED50 15.8 mg/kg in P. bergheiinfected mice. The extracts coded as HA-2 at 30 mg/kg and VC-1 at 20 mg/kg exhibited parasite inhibition in mice: 73.2% and 63.0% respectively. Of these two plant extracts, petroleum ether extract ofV. canescens was found slightly cytotoxic. Conclusion: The present investigation reflects the use of these traditional medicinal plants against malaria and these plants may work as potential source in the development of variety of herbal formulations for the treatment of malaria. 4. Mathur A, Verma SK, Yousuf S, Singh SK, Prasad GBKS, Dua VK. Antimicrobia Potential of roots of Riccinus communis against pathogenic microorganisms. Int J Pharma Biosci 2011; 2(1): 545-8. ABSTRACT Antimicrobial activity of various extracts of roots (200mg/ml) of Ricinus communis were screened against pathogenic microorganisms such as Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa, Salmonella typhimurium, Proteus vulgaris, Bacillus subtilis, Candida albicans and Aspergillus niger using well diffusion method. Aqueous extracts don’t show any significant antimicrobial properties. The hexane and methanol extracts revealed maximum antimicrobial activity (p<0001). These findings established the potential of the roots of Ricinus 3 Annotated Bibliography of NIMR (Publications: 2011-2015) NIMR Library communis as an effective antimicrobial agent. However, further studies are needed to evaluate active compounds and probable medicinal benefits in chemotherapy among humans. KEYWORDS: Ricinus communis, pathogenic microorganisms, methanol extracts, hexane extracts and chemotherapy. 5. Mathur A, Verma SK, Singh SK, Prakash A, Prasad A, Prasad GBKS, Dua VK. Anti- inflammatory activity of earthworm extracts. Int J Pharmaceut Sci Res 2011; 2(2): 278-81. ABSTRACT Earthworm plays a major role in the proper functioning of the soil ecosystem. It acts as scavenger and helps in recycling of dead and decayed plant material by feeding on them. Earthworm increases the soil fertility and is often referred to as a farmer’s friend. Earthworms have been used in medicine for various remedies. In the present investigation, various solvent extracts of an earthworm, Eudrilus eugeniae were prepared and antiinflammatory activity of these extracts were determined. The petroleum ether fraction possessed maximum anti-inflammatory activity in carrageenan induced albino rats in comparison to 95% ethanol and 0.2 M phosphate buffer (pH, 7.0) extracts. The paw volume was determined and was compared with that of aspirin, a standard anti-inflammatory drug. The results indicates that petroleum ether fraction of earthworm extract possessed similar anti-inflammatory activity as that of aspirin. KEYWORDS: Eudrilus eugeniae, anti-inflammatory activity, 95% ethanol, petroleum ether, 0.2 M phosphate buffer (pH, 7.0). 6. Shah NK, Dhillon GP, Dash AP, Arora U, Meshnick SR, Valecha N. Antimalarial drug resistance of Plasmodium falciparum in India: changes over time and space. Lancet Infect Dis 2011; 11(1): 57-64. ABSTRACT After the launch of the National Malaria Control Programme in 1953, the number of malaria cases reported in India fell to an all-time low of 0•1 million in 1965. However, the initial success could not be maintained and a