PDF Output of CLIC (clustering by inferred co-expression) Dataset: Num of genes in input gene set: 93 Total number of genes: 16493 CLIC PDF output has three sections: 1) Overview of Co-Expression Modules (CEMs) Heatmap shows pairwise correlations between all genes in the input query gene set. Red lines shows the partition of input genes into CEMs, ordered by CEM strength. Each row shows one gene, and the brightness of squares indicates its correlations with other genes. Gene symbols are shown at left side and on the top of the heatmap. 2) Details of each CEM and its expansion CEM+ Top panel shows the posterior selection probability (dataset weights) for top GEO series datasets. Bottom panel shows the CEM genes (blue rows) as well as expanded CEM+ genes (green rows). Each column is one GEO series dataset, sorted by their posterior probability of being selected. The brightness of squares indicates the gene's correlations with CEM genes in the corresponding dataset. CEM+ includes genes that co-express with CEM genes in high-weight datasets, measured by LLR score. 3) Details of each GEO series dataset and its expression profile: Top panel shows the detailed information (e.g. title, summary) for the GEO series dataset. Bottom panel shows the background distribution and the expression profile for CEM genes in this dataset. Overview of Co-Expression Modules (CEMs) with Dataset Weighting Scale of average Pearson correlations Num of Genes in Query Geneset: 93. Num of CEMs: 1. 0.0 0.2 0.4 0.6 0.8 1.0 Aurka Bub1 Plk1 Cdc20 Ccnb2 Sgol1 Espl1 Fbxo5 Cdc25c Ccne2 Ccne1 Pkmyt1 Smc1a Ccnb1 Smc3 Anapc1 Anapc5 Anapc2 Ppp2r1a Ywhah Ywhaz Rps6ka1 Itpr1 Itpr3 Btrc Ppp2ca Rps6ka2 Cpeb1 Adcy4 Adcy6 Anapc7 Adcy9 Calml3 Adcy8 Rec8 Igf1 Pttg1 Prkacb Ywhag Ywhaq Ywhab Adcy7 Pgr Itpr2 Ppp3r1 Ppp2cb Adcy3 Ins2 Plcz1 Camk2d Ar Ppp2r5a Anapc4 Camk2g Cdc26 Prkx Fbxw11 Cdc27 Ppp1cb Ywhae Ppp3ca Ppp2r5b Rps6ka3 Fbxo43 Ppp3cb Ppp2r1b Ppp2r5e Anapc10 Spdya Rps6ka6 Ppp3cc Chp2 Cdc16 Slk Camk2a Ppp3r2 Adcy5 Cdc23 Adcy1 Cdk2 Camk2b Smc1b Mapk12 Prkaca Ppp2r5d Calm4 Mos Anapc13 Adcy2 Anapc11 Ppp1ca Stag3 Mad2l2 Aurka Bub1 Plk1 Cdc20 Ccnb2 Sgol1 Espl1 Fbxo5 Cdc25c CEM 1 (626 datasets) Ccne2 Ccne1 Pkmyt1 Smc1a Ccnb1 Smc3 Anapc1 Anapc5 Anapc2 Ppp2r1a Ywhah Ywhaz Rps6ka1 Itpr1 Itpr3 Btrc Ppp2ca Rps6ka2 Cpeb1 Adcy4 Adcy6 Anapc7 Adcy9 Calml3 Adcy8 Rec8 Igf1 Pttg1 Prkacb Ywhag Ywhaq Ywhab Adcy7 Pgr Itpr2 Ppp3r1 Ppp2cb Adcy3 Ins2 Plcz1 Camk2d Ar Ppp2r5a Anapc4 Camk2g Cdc26 Singletons Prkx Fbxw11 Cdc27 Ppp1cb Ywhae Ppp3ca Ppp2r5b Rps6ka3 Fbxo43 Ppp3cb Ppp2r1b Ppp2r5e Anapc10 Spdya Rps6ka6 Ppp3cc Chp2 Cdc16 Slk Camk2a Ppp3r2 Adcy5 Cdc23 Adcy1 Cdk2 Camk2b Smc1b Mapk12 Prkaca Ppp2r5d Calm4 Mos Anapc13 Adcy2 Anapc11 Ppp1ca Stag3 Mad2l2 Symbol Num ofCEMGenes:17.Predicted546.SelectedDatasets:626.Strength:79.0 CEM 1,Geneset"[K]Oocytemeiosis",Page1 Mis18bp1 Racgap1 Ncapd2 Shcbp1 Nusap1 Anapc5 Anapc1 Pkmyt1 Cdc25c Smc1a Incenp Bub1b Ncaph Cenpe Ncapg Ccnb1 Ccnb2 Rad51 Spag5 Cdca5 Cdca8 Ube2c Kif20a Ccna2 Ccne1 Ccne2 Cdc20 Fbxo5 Aurkb Aurka Cenpf Mki67 Asf1b Cenpi Aspm Sgol1 Smc3 Espl1 Birc5 Bub1 Kif22 Kif11 Cdk1 Tpx2 Melk Nuf2 Prc1 Plk1 Kif4 Pbk 0.0 1.0 GSE40513 [6] GSE16874 [12] GSE17266 [59] Only showingfirst200datasets-Seetxtoutputforfulldetails. GSE53916 [6] GSE17794 [44] GSE39621 [51] GSE54215 [13] GSE6998 [32] GSE13225 [6] GSE46797 [6] GSE21224 [16] GSE57543 [6] GSE44260 [10] GSE13874 [14] GSE15303 [11] GSE31028 [6] GSE4694 [6] GSE27605 [8] GSE17796 [39] GSE48382 [10] GSE51385 [8] GSE17316 [12] GSE26290 [12] GSE30192 [6] GSE51883 [30] GSE20954 [14] GSE54490 [12] GSE51243 [7] GSE39449 [6] GSE7875 [16] GSE34839 [6] GSE25257 [6] GSE27786 [20] GSE21299 [12] GSE51075 [12] GSE12454 [13] GSE6957 [12] GSE54653 [6] GSE9287 [8] GSE29241 [6] GSE33308 [10] GSE15741 [6] GSE46185 [6] GSE6837 [8] GSE23845 [15] GSE26616 [6] GSE12498 [12] GSE21716 [28] GSE6875 [8] GSE12881 [6] GSE18135 [18] GSE21309 [9] GSE52474 [154] GSE32386 [13] GSE39034 [9] GSE16675 [72] GSE9763 [20] GSE45051 [18] GSE41342 [26] GSE17509 [57] GSE47959 [8] GSE12993 [6] GSE7020 [8] GSE45143 [6] GSE46209 [21] GSE31359 [8] GSE28621 [21] GSE46090 [12] GSE21900 [12] GSE30160 [6] GSE14769 [24] GSE12001 [6] GSE21379 [10] GSE10525 [18] GSE39082 [6] GSE22774 [6] GSE20302 [12] GSE11220 [44] GSE48397 [10] GSE24512 [29] GSE46606 [30] GSE28457 [24] GSE16684 [6] GSE34324 [12] GSE4260 [6] GSE8039 [32] GSE10176 [6] GSE6689 [12] GSE22180 [60] GSE28417 [12] GSE23502 [8] GSE15326 [10] GSE51628 [15] GSE13873 [27] GSE18326 [8] GSE7694 [12] GSE24628 [16] GSE4535 [6] GSE23505 [10] GSE8678 [6] GSE32330 [12] GSE27901 [23] GSE17745 [6] GSE21278 [48] GSE13611 [8] GSE15610 [12] GSE18115 [8] GSE13693 [9] GSE20100 [15] GSE33471 [12] GSE22124 [18] GSE50813 [24] GSE30745 [12] GSE39984 [18] GSE30485 [15] GSE18993 [13] GSE7657 [12] GSE30962 [16] GSE22005 [23] GSE11222 [42] GSE26355 [6] GSE23925 [6] GSE9247 [15] GSE19729 [14] GSE8660 [6] GSE13259 [10] GSE8960 [18] GSE32277 [33] GSE19885 [9] GSE20500 [6] GSE8025 [21] GSE31099 [24] GSE15872 [18] GSE31313 [22] GSE34729 [6] GSE20696 [8] GSE4768 [18] GSE28389 [20] GSE19925 [6] GSE27379 [6] GSE5041 [8] GSE5891 [6] GSE7460 [52] GSE45465 [39] GSE18534 [15] GSE40856 [8] GSE19004 [9] GSE13692 [8] GSE21491 [9] GSE49194 [14] GSE15267 [8] GSE43419 [20] GSE11201 [18] GSE18460 [16] CEM+ CEM GSE7503 [6] GSE24210 [16] GSE11818 [6] GSE48004 [6] GSE38031 [8] GSE27546 [51] 0.0 GSE7897 [60] GSE21711 [6] GSE47421 [24] Scale ofaveragePearsoncorrelations GSE9975 [36] GSE19369 [8] GSE13635 [6] GSE1435 [27] GSE12518 [6] GSE51608 [6] 0.2 GSE15580 [14] GSE7225 [9] GSE11186 [33] GSE42021 [27] GSE3126 [6] GSE2019 [12] GSE30083 [12] GSE12465 [14] GSE4142 [14] 0.4 GSE36530 [6] GSE12581 [16] GSE18281 [33] GSE14012 [24] GSE8156 [6] GSE51804 [10] GSE24121 [9] GSE45895 [27] GSE21054 [8] 0.6 GSE53951 [10] GSE45820 [6] GSE21393 [6] GSE11110 [11] GSE13563 [6] GSE46242 [12] GSE17097 [20] GSE29318 [9] GSE48203 [9] 0.8 GSE11382 [10] GSE31598 [12] GSE13149 [25] GSE33156 [18] Score 213.97 215.07 215.65 217.13 219.76 221.45 222.06 224.16 226.00 226.01 226.51 226.74 229.94 230.12 230.21 234.31 234.74 234.74 234.92 237.00 237.31 237.94 240.03 241.68 241.75 242.39 245.71 248.11 250.11 250.98 252.77 256.09 261.40 1.0 Notes Symbol Num ofCEMGenes:17.Predicted546.SelectedDatasets:626.Strength:79.0 CEM 1,Geneset"[K]Oocytemeiosis",Page2 Arhgap11a Rad51ap1 Depdc1a Ncapg2 Ckap2l Zwilch Cenpp Cenpn Cenph Kpna2 Cenpk Kif18b Ercc6l Kif18a Cks1b Cdc45 Cep55 Cdca2 Ckap2 Ndc80 Esco2 Spc24 Fignl1 Mcm7 Mcm5 Gins1 Prim1 Brca1 Atad2 Kntc1 Spdl1 Sgol2 Uhrf1 Rrm2 Rrm1 Cdc6 Cks2 Exo1 Nek2 Ska3 Dbf4 Anln Ccnf Rfc5 Pole Ect2 Plk4 Lig1 Tk1 Stil 0.0 1.0 GSE40513 [6] GSE16874 [12] GSE17266 [59] Only showingfirst200datasets-Seetxtoutputforfulldetails. GSE53916 [6] GSE17794 [44] GSE39621 [51] GSE54215 [13] GSE6998 [32] GSE13225 [6] GSE46797 [6] GSE21224 [16] GSE57543 [6] GSE44260 [10] GSE13874 [14] GSE15303 [11] GSE31028 [6] GSE4694 [6] GSE27605 [8] GSE17796 [39] GSE48382 [10] GSE51385 [8] GSE17316 [12] GSE26290 [12] GSE30192 [6] GSE51883 [30] GSE20954 [14] GSE54490 [12] GSE51243 [7] GSE39449 [6] GSE7875 [16] GSE34839 [6] GSE25257 [6] GSE27786 [20] GSE21299 [12] GSE51075 [12] GSE12454 [13] GSE6957 [12] GSE54653 [6] GSE9287 [8] GSE29241 [6] GSE33308 [10] GSE15741 [6] GSE46185 [6] GSE6837 [8] GSE23845 [15] GSE26616 [6] GSE12498 [12] GSE21716 [28] GSE6875 [8] GSE12881 [6] GSE18135 [18] GSE21309 [9] GSE52474 [154] GSE32386 [13] GSE39034 [9] GSE16675 [72] GSE9763 [20] GSE45051 [18] GSE41342 [26] GSE17509 [57] GSE47959 [8] GSE12993 [6] GSE7020 [8] GSE45143 [6] GSE46209 [21] GSE31359 [8] GSE28621 [21] GSE46090 [12] GSE21900 [12] GSE30160 [6] GSE14769 [24] GSE12001 [6] GSE21379 [10] GSE10525 [18] GSE39082 [6] GSE22774 [6] GSE20302 [12] GSE11220 [44] GSE48397 [10] GSE24512 [29] GSE46606 [30] GSE28457 [24] GSE16684 [6] GSE34324 [12] GSE4260 [6] GSE8039 [32] GSE10176 [6] GSE6689 [12] GSE22180 [60] GSE28417 [12] GSE23502 [8] GSE15326 [10] GSE51628 [15] GSE13873 [27] GSE18326 [8] GSE7694 [12] GSE24628 [16] GSE4535 [6] GSE23505 [10] GSE8678 [6] GSE32330 [12] GSE27901 [23] GSE17745 [6] GSE21278 [48] GSE13611 [8] GSE15610 [12] GSE18115 [8] GSE13693 [9] GSE20100 [15] GSE33471 [12] GSE22124 [18] GSE50813 [24] GSE30745 [12] GSE39984 [18] GSE30485 [15] GSE18993 [13] GSE7657 [12] GSE30962 [16] GSE22005 [23] GSE11222 [42] GSE26355 [6] GSE23925 [6] GSE9247 [15] GSE19729 [14] GSE8660 [6] GSE13259 [10] GSE8960 [18] GSE32277 [33] GSE19885 [9] GSE20500 [6] GSE8025 [21] GSE31099 [24] GSE15872 [18] GSE31313 [22] GSE34729 [6] GSE20696 [8] GSE4768 [18] GSE28389 [20] GSE19925 [6] GSE27379 [6] GSE5041 [8] GSE5891 [6] GSE7460 [52] GSE45465 [39] GSE18534 [15] GSE40856 [8] GSE19004 [9] GSE13692 [8] GSE21491 [9] GSE49194 [14] GSE15267 [8] GSE43419 [20] GSE11201 [18] GSE18460 [16] CEM+ CEM GSE7503 [6] GSE24210 [16] GSE11818 [6] GSE48004 [6] GSE38031 [8] GSE27546 [51] 0.0 GSE7897 [60] GSE21711 [6] GSE47421 [24] Scale ofaveragePearsoncorrelations GSE9975 [36] GSE19369 [8] GSE13635 [6] GSE1435 [27] GSE12518 [6] GSE51608 [6] 0.2 GSE15580 [14] GSE7225 [9] GSE11186 [33] GSE42021 [27] GSE3126 [6] GSE2019 [12] GSE30083 [12] GSE12465 [14] GSE4142 [14] 0.4 GSE36530 [6] GSE12581 [16] GSE18281 [33] GSE14012 [24] GSE8156 [6] GSE51804 [10] GSE24121 [9] GSE45895 [27] GSE21054 [8] 0.6 GSE53951 [10] GSE45820 [6] GSE21393 [6] GSE11110 [11] GSE13563 [6] GSE46242 [12] GSE17097 [20] GSE29318 [9] GSE48203 [9] 0.8 GSE11382 [10] GSE31598 [12] GSE13149 [25] GSE33156 [18] Score 176.94 177.48 177.60 177.85 178.59 178.96 179.72 179.72 181.77 182.86 186.04 186.53 187.04 188.34 188.58 188.81 190.47 191.07 191.66 192.53 193.20 193.67 193.89 195.17 196.65 196.68 196.78 197.84 198.13 200.22 200.22 200.45 202.02 203.08 203.16 204.41 205.02 205.17 205.83 206.29 206.54 207.68 207.86 208.77 208.80 208.80 209.81 211.62 213.03 213.86 1.0 Notes Symbol Num ofCEMGenes:17.Predicted546.SelectedDatasets:626.Strength:79.0 CEM 1,Geneset"[K]Oocytemeiosis",Page3 BC055324 Arhgef39 Depdc1b Suv39h1 Mms22l Rad54b Topbp1 Parpbp Chaf1b Cenpm Wdhd1 Cenpw Iqgap3 Dnmt1 Cenpu Chtf18 Cdkn3 Trip13 Casc5 Gmnn Hirip3 Mcm6 Mcm2 Mcm4 Mybl2 Gins2 Prim2 Cenpl Atad5 Ube2t H2afx Pole2 Eme1 Pola1 Tcf19 Prr11 Mastl Gsg2 Rpa2 Pcna Hells Tipin Ezh2 Fen1 Oip5 Rfc4 E2f8 E2f7 Blm Pif1 0.0 1.0 GSE40513 [6] GSE16874 [12] GSE17266 [59] Only showingfirst200datasets-Seetxtoutputforfulldetails.