Table 1. DNA Content of Chordate Cell Nuclei DNA Content Species (Synonym) Cell Type or Source pg/nucleus Reference Mammalia Man Brain cortex 7.1 31 Stomach 5.36 49 Liver 5.8–6.3 87 5.64–22.1 49 10.83 18 Pancreas 5.18 49 Cecum 5.16 49 Lung 6.04 49 WI-38 (embryonic lung fibroblast) 7.94 11 Leukocytes 6.85 52 Normal 6.92 56 11.06 30 Blood 7.63 18 Bone marrow 9.41 18 Leukemic 3.8 30 Bone marrow Lymphocytic leukemia 7.37 54 Granulocytic leukemia 8.88 54 Lymphocytes 5.06 49 5.61 82 6.50 55 Kidney 6.34 49 8.99 18 Sperm 1.15–3.50 57 2.43 45 2.44 49 2.7–3.4 72 3.40 18 Infertile 2.0 45 Prostate 9.43 18 Breast 6.50 49 Amnion, primary cell 18.8 29 HeLa (human cervix carcinoma) 14.4 13, 62 15.8 51 17 50 Suprarenal gland 9.1 43 Skin 5.60 49 Buffalo Sperm 4.90 22 Cat Brain cortex 7.1 31 Cattle Liver 5.9–6.2 47 5.9–10.5 48 6.1–6.4 86 6.22–8.4 58 6.4 87 Continued 1 Table 1. Continued Species (Synonym) Cell Type or Source DNA Content Reference pg/nucleus 6.5 70 6.8 46 Tetraploid 19.1 48 Pancreas 6.9 86, 87 Leukocytes 6.93–6.98 52 Lymphocytes 6.4 72 Spleen 7.0 46 Lymph node 7.03 58 Kidney 5.9 86 6.0 87 6.25–6.81 58 Sperm 2.8–3.3 47, 48 2.82 58 2.95 75 3.0 81 3.04 45 3.2 72, 89 3.24 71 3.3 86 3.9 91 4.44 21 Infertile 2.16 45 Calf Thymus 5.7–6.4 48 6.4 89 6.4–6.8 86 6.6 87 6.66 23 6.8 41 6.9 81 7.15 58 7.9 24 Dog Brain cortex 6.5 31 Liver 5.0–5.5 87 7.2 4 Leukocytes 6.73 52 Splenic lymphocytes 6.39 55 Kidney 5.3 87 Guinea pig Liver 5.9 86, 87 Horse Liver 5.8 87 Mouse Liver 6.0 87 6.6 10 12.3 43 Tetraploid 12.6 81 Octaploid 25.1 81 Hexadecaploid 48.8 81 Leukocytes 5.52 95 Transplant leukemia, AK4 7.4 61 9421 7.5 61 Lymphocytes 5.31 55 Continued 2 Table 1. Continued Species (Synonym) Cell Type or Source DNA Content Reference pg/nucleus 5.64 82 6.6 61 Granulocytic leukemia, C 1498 7.48 55 Spleen 6.5 65 8.3 37 Spontaneous leukemia 7.3 61 Thymus 7.9 94 8.78 73 Kidney 5.0 87 Fibroblasts, embryonic 5.1 7 LP-3 24.3 60 Carcinoma Krebs 7.0 38 Lettre-Ehrlich, hyperdiploid 11.1 37 Ehrlich, hypotetraploid 18.0 37 Ehrlich ascites cells 12.9–14.0 47 14.2 38 20.0 39 Ascites lymphoma, L1 32.2 73 L2 10.9 73 Cloudman S91 melanoma, tetraploid 16.6 37 6C3HED Lymphoma, diploid 9.8 37 6C3HED-DBA2 Lymphoma, hypotetraploid 15.3 37 DBA Ascites lymphoma 6.7 47 E9514A Lymphoma, diploid 7.9 37 Brush-tailed possum1 Unspecified 6.0 69 Rabbit Liver 5.3 87 7.23 16 Lymphocytes 5.75 72 Kidney, KD cell 8.7 51 Sperm 3.1 91 3.25 72 Rat Submaxillary gland 10.5 43 Salivary gland 6.85 78 Liver 5.9–9.4 15 6.0–8.6 48 6.9 93 7.8 20 7.98–9.31 78 8.2 46 10.8 2 11.5–13.0 43 JTC-25.P3 22.5 60 Pancreas 7.41 78 10.35 43 Small intestine 7.50 78 Lung 6.55 78 Leukocytes 6.1 81 6.75 78 Continued 3 Table 1. Continued Species (Synonym) Cell Type or Source DNA Content Reference pg/nucleus Lymphocytes 5.58 82 6.05 72 Bone marrow 6.90 78 Spleen 6.0–6.5 15 6.92 78 Thymus 6.1–6.3 15 6.72 23 7.2 78 Kidney 5.5 46 5.7 81 6.82 78 9.25 43 9.75 42 13.4 63 Spermatocytes, primary 15.2 24 Sperm 3.11 72 3.9 24 Sheep Liver 5.4–6.1 87 5.7 84 Leukocytes 6.83 52 Sperm 2.57 22 2.9 1, 91 Swine Liver 4.7–5.0 86 5.0 87 Leukocytes 6.85 52 Kidney 5.2 86, 87 Sperm 3.44 35 Aves Agelaius phoeniceus Liver 3.7 5 Ardea herodias Liver 4.1 5 Cyanocitta cristata Liver 3.6 5 Dendroica coronata Liver 3.8 5 D. dominica Liver 3.9 5 D. palmarum Liver 4.4 5 Gallus gallus Erythrocytes 1.43 21 Sperm 0.73 21 (G. domesticus)2 Liver 2.39 58 2.45 70 2.52–2.77 17 3.5 5 Pancreas 2.51–2.83 16 Heart 2.67–2.75 16 Erythrocytes 1.70 41 2.2 89 2.34 58 2.4 83 Continued 4 Table 1. Continued Species (Synonym) Cell Type or Source DNA Content Reference pg/nucleus 2.5 81 2.54 66 2.62 16 2.63–2.70 17 3.1 91 3.30 72 Spleen 2.60–2.72 16 Kidney 2.38–2.57 16 Sperm 0.95 74 1.26 58 1.50 72 Fibroblasts 2.3 81 Embryo 1.4 91 Larus atricilla Liver 4.0 5 Melopsittacus undulatus Liver 3.3 5 Numida meleagris3 Diploid 2.27 85 Parus carolimemsis Liver 4.1 5 Pelecanus occidentalis Liver 3.9 5 Phalacrocorax auritus Liver 4.0 5 Pipilo erythrophthalmus Liver 3.6 5 Podiceps auritus Liver 4.2 5 Polioptila caerulea Liver 3.8 5 Regulus calendula Liver 3.7 5 Sayornis phoebe Liver 4.0 5 Serinus canarius Liver 4.1 5 Sialia sialis Liver 4.0 5 Sturnella magna Liver 4.1 5 Sturnus vulgaris Liver 3.6 5 Thalasseus sandvicensis Liver 3.9 5 Toxostoma rufum Liver 3.5 5 Duck Liver 2.1 87 Erythrocytes 2.3 85 2.65 85 Goose Diploid 1.9 88 2.92 85 Pheasant Diploid 1.7 88 Pigeon Diploid 2.0 88 Sparrow Diploid 1.9 88 Turkey Diploid 1.9 88 Reptilia Chelonia mydas Liver 4.6–5.1 70 5.12 58 Erythrocytes 5.27 58 Alligator Erythrocytes 4.98 85 Black racer snake Erythrocytes 2.85 85 Pilot snake Erythrocytes 4.28 85 Continued 5 Table 1. Continued Species (Synonym) Cell Type or Source DNA Content Reference pg/nucleus Water snake Erythrocytes 5.02 85 Snapping turtle Erythrocytes 4.97 85 Wood turtle Erythrocytes 4.92 85 Amphibia Alytes obstetricans Liver 21.0 14 Ambystoma mexicanum Liver 77.0 14 (Siredon mexicanum) Liver 10.7 24 Erythrocytes 6.88 23 11.2 24 Spermatocytes, primary 18.0 24 Sperm 3.36; 4.8 23, 24 Epithelium 10.9 24 A. tigrinum Liver 85.3 14 Amphiuma Erythrocytes 168 85 A. means Liver 192.8 14 Bombina bombina Liver 27.4 14 Bufo alvarius Erythrocytes 11.3 3 B. americanus Liver 10.8 14 Erythrocytes 12.7 3 B. bufo Liver 14.2 14 Erythrocytes 14.6 3 B. calamita Liver 9.2 14 Erythrocytes 10.7 3 B. fowleri Liver 12.6 14 Erythrocytes 14.2 3 B. marinus Liver 9.7 14 Erythrocytes 11.3 3 B. quercicus Erythrocytes 9.8 3 B. regularis Erythrocytes 8.9 3 B. retiformis Erythrocytes 13.4 3 B. terrestris Erythrocytes 11.1 3 B. valliceps Erythrocytes 9.2 3 B. viridis Erythrocytes 11.4 3 12.11 72 Sperm 5.4 72 Desmognathus fuscus Liver 36.0 14 Eurycea bislineata Liver 47.0 14 Hyla septentrionalis Liver 4.4 14 H. squirella Liver 10.4 14 Necturus Erythrocytes 48.4 85 N. lewisi Liver 270.0 14 N. maculosus Liver 196.8 14 N. punctatus Liver 264.0 14 Notophthalmus viridescens Liver 93.2 14 (Triturus viridescens) Diploid 98 76 Proteus anguinus Liver 105.1 14 Continued 6 Table 1. Continued Species (Synonym) Cell Type or Source DNA Content Reference pg/nucleus Rana catesbeiana Liver 15.2 14 R. esculenta Liver 14.1 14 Erythrocytes 14.6 53 Sperm 6.9 53 R. pipiens Liver 7.4–8.3 27 10.4 77 15.0 14 15.7 58 15.76 25 Erythrocytes 15.0 19, 58 Sperm 6.48 25 Ova 13.27 25 Embryo, late 13–16 77 14 9 R. temporatria Liver 8.8 14 Erythrocytes 8.2 91 8.9 72 (R. platyrrhina) Sperm 11–13 34 Scaphiopus bombifrons Liver 2.4 14 Triturus alpestris Liver 75.2 14 T. cristatus Liver 52.5 14 Erythrocytes 45.0 91 T. vulgaris Liver 71.0 14 Xenopus laevis Diploid 8.4 9 Liver 7.5 14 Erythrocytes 6.0 92 6.3 19 Toad Erythrocytes 7.33 58 Sperm 3.70 58 Dipnoi Protopterus Erythrocytes 100 85 Crossopterygii Latimeria chalumnae Erythrocytes 5.6 90 13.2 79 Osteichthyes Acanthurus chirurgus Erythrocytes 1.38 59 (A. hepatus) Acipenser stellatus Sperm 2.12–2.5 36 A. sturio Erythrocytes 3.2 59 Aequidens portalegrensis Haploid 1.2 32 Alosa pseudoharengus Haploid 1.4 32 (Pomolobus pseudoharengus) Continued 7 Table 1. Continued Species (Synonym) Cell Type or Source DNA Content Reference pg/nucleus A.