Authors: Ron Caspi Pedro R. Romero Peter D. Karp Carol Fulcher Jonathan Wagg An online version of this diagram is available through BioCyc.org and may be used for analysis of omics datasets. Lines in the diagram correspond to reactions; nodes correspond to metabolites. Markus Krummenacker Dan Weaver Pathways are colored according to their cellular function, such as biosynthesis of cofactors. HumanCyc: Homo sapiens Cellular Overview Reactions not assigned to any pathway are in the far right of the cytoplasm. Peter E Midford Dheepika Weerasinghe In the membrane are transporters (with arrows) and other membrane proteins. gly cys gln arg gln a monocarboxylate a monocarboxylate a monocarboxylate gly ser thr asn chloride arg creatine sn-glycerol lactate lactate lactate ala pro (R)- gln connections between pathways are omitted for legibility. sulfate met ser gly serotonin hydrogencarbonate leu phosphate 3-phosphate (R)-3-hydroxybutanoate (R)-3-hydroxybutanoate (R)-3-hydroxybutanoate pro noradrenaline [+ 4 more] ala [+ 2 more] [+ 2 more] [+ 2 more] [+ 3 more] cAMP- Na+ Segment Sodium- Sodium- Sodium- Advanced TC10/ Zinc finger dependent HLA class I HLA class I HLA class I Sodium- dependent HLA class I T-cell HLA class I Putative HLA class I HLA class I HLA class I TBC1 krev polarity Thrombospondin Immunoglobulin Immunoglobulin Carcinoembryonic Immunoglobulin Ras GTPase- N-formyl y+LAT- Immunoglobulin Glycerol-3- coupled Chloride coupled y+LAT- Neural cell Immunoglobulin dependent Olfactory glycosylation ADP- CDC42 MYND Src kinase- protein Olfactory histocompatibility Immunoglobulin Immunoglobulin Olfactory Immunoglobulin Immunoglobulin Integrin beta- histocompatibility Serine histocompatibility Olfactory Immunoglobulin Protocadherin Sulfate dependent neutral Immunoglobulin histocompatibility Transmembrane receptor histocompatibility olfactory histocompatibility Olfactory Immunoglobulin Immunoglobulin histocompatibility histocompatibility Olfactory Immunoglobulin Lymphocyte domain interaction protein type-1 domain- Bw-22 Aw-69 Nav1.6 lambda kappa antigen-related cell kappa Loricrin activating SSc5D peptide Siah-1 2/4F2hc AS250 heavy Aw-19 SPR-2E CT1 hPD-1 phosphate MCT 1 MCT 2 MCT 3 hPAT1 ASCT1 neutral 5HTT NBCe2 anion NET neutral 2/4F2hc adhesion kappa CSF-1R phosphate receptor B’DT end product- P2Y4 Bw-41 PAP-IV HERV-K Aw-66 Tetraspanin-17 Tetraspanin-6 E-NPP4 Semaphorin-3F CD99 c-FLIP TFPI CAT-2 ribosylation Plexin-D1 GTPase- CT2 domain- citrin LRP-12 AE 1 CT-R BSSP-4 associated ANT 2 IMP4 kinase receptor 8G2 antigen, B-67 heavy variable 4-31 heavy variable 3-64 receptor 5H2 heavy variable 5-51 heavy variable 4-28 like protein 1 antigen, Cw- protease 41 antigen, B-82 receptor 2T10 heavy variable 3-53 gamma-B3 transporter proline amino acid heavy constant mu antigen, Cw- protease serine 2 alpha chain V antigen, B-39 receptor 8G3 antigen, Cw- receptor 13C7 heavy variable 3-13 kappa variable 6-21 antigen, B-18 antigen, A-23 receptor 2T5 kappa variable 1-12 antigen 6L family trapped dishevelled containing HLA class I variable 4-3 variable 1D-8 adhesion molecule 20 variable 3D-11 protein 4B receptor 3 complex variable 4-30-2 transporter amino acid exchanger amino acid complex molecule L1 variable 3D-7 transport 2A1/2A42 specific factor 5 activating containing phosphoprotein 2 type II-beta alpha chain 6 alpha chain alpha chain transporter transporter 18 alpha chain region PY14 alpha chain pseudogene 1 alpha chain alpha chain alpha chain member 3D protein 1 homolog protein 7A histocompatibility transporter 5 transporter 1 protein 2C receptor protein protein 10 regulatory Immunoglobulin B(0)AT3 DVL-2 antigen, Cw- a monocarboxylate a monocarboxylate subunit kappa variable 1-13 a monocarboxylate cys 5 alpha chain lactate lactate gly (R)- lactate thr serotonin hydrogencarbonate creatine sn-glycerol (R)-3-hydroxybutanoate (R)-3-hydroxybutanoate (R)-3-hydroxybutanoate sulfate ala gln noradrenaline arg arg gly ser hydrogencarbonatechloride 3-phosphate [+ 2 more] [+ 2 more] [+ 2 more] pro asn leu pro ser ala hydrogencarbonate gln phosphate gln gly Arg3.