Rubin 5e Suggested Readings P. 1 of 97 Chapter 1 Baldwin KM, Haddad F: Skeletal muscle plasticity: Cellular and molecular responses to altered physical activity paradigms. Am J Phys Med Rehabil 81:S40–51, 2002. Bohr VA: Repair of oxidative DNA damage in nuclear and mitochondrial DNA, and some changes with aging in mammalian cells. Free Radic Biol Med 32:804–812, 2002. Copin MC, Buisine MP, Devisme L, et al.: Normal respiratory mucosa, precursor lesions and lung carcinomas: Differential expression of human mucin genes. Frontiers Biosci 6:D1264–1275, 2001. Faragher RG: Cell senescence and human aging: Where’s the link? Biochem Soc Trans 28:221–226, 2000. Farout L, Friguet B: Proteasome function in aging and oxidative stress: Implications in protein maintenance failure. Antiox Redox Signal 8:205–216, 2006. Giffard RG, Xu L, Zhao H, et al.: Chaperones, protein aggregation, and brain protection from hypoxic/ischemic injury. J Exp Biol 207:3213–3220, 2004. Glass DJ: Signalling pathways that mediate skeletal muscle hypertrophy and atrophy. Nat Cell Biol 5:87–90, 2003. Granger MP, Wright WE, Shay JW: Telomerase in cancer and aging. Crit Rev Oncol Hematol 41:29–40, 2002. Greider CW: Cellular responses to telomere shortening: Cellular senescence as a tumor suppressor mechanism. Harvey Lectures 96:33–50, 2000–2001. Harkema JR, Wagner JG: Non-allergic models of mucous cell metaplasia and mucus hypersecretion in rat nasal and pulmonary airways. Novartis Found Symp 248:181–197, 2002. Rubin 5e Suggested Readings P. 2 of 97 Henry CJ: Mechanisms of changes in basal metabolism during ageing. Eur J Clin Nutr 54:S77–91, 2000. Higami Y, Shimokawa I: Apoptosis in the aging process. Cell Tissue Res 301:125–132, 2000. Hodes RJ, Hathcock KS, Weng NP: Telomeres in T and B cells. Immunology 2:699–706, 2002. Holleyman CR, Larson DF. Apoptosis in the ischemic reperfused myocardium. Perfusion 16:491–502, 2001. Hursting SD, Lavigne JA, Berrigan D, et al.: Calorie restriction, aging, and cancer prevention: Mechanisms of action and applicability to humans. Annu Rev Med 54:131– 52, 2003. Iverson SL, Orrenius S: The cardiolipin-cytochrome c interaction and the mitochondrial regulation of apoptosis. Arch Biochem Biophys 423:37–46, 2004. Jaeschke H: Molecular mechanisms of hepatic ischemia-reperfusion injury and preconditioning. Amer J Physiol: Gastrointest Liver Physiol 284:G15–26, 2003. Jaeschke H, Knight TR, Bajt ML: The role of oxidant stress and reactive nitrogen species in acetaminophen hepatotoxicity. Toxicol Letts 144:279–288, 2003. Jassem W, Fuggle SV, Rela M, et al.: The role of mitochondria in ischemia/reperfusion injury. Transplantation 73:493–499, 2002. Jenkins GJ, Doak SH, Parry JM, et al.: Genetic pathways involved in the progression of Barrett’s metaplasia to adenocarcinoma. Br J Surg 89:824–837, 2002. Kaminski KA, Bonda TA, Korecki J, et al.: Oxidative stress and neutrophil activation: The two keystones of ischemia/reperfusion injury. Int J Cardiol 86:41–59, 2002. Rubin 5e Suggested Readings P. 3 of 97 Keller JN, Dimayuga E, Chen Q, et al.: Autophagy, proteasomes, lipofucsin, and oxidative stress in the aging brain. Int J Biochem Cell Biol 36:2376–2391, 2004. Kolesnick R, Fuks Z: Radiation and ceramide-induced apoptosis. Oncogene 22:5897– 5906, 2003. Kowald A: The mitochondrial theory of aging. Biol Signals Receptors 10:162–175, 2001. Kukan M: Emerging roles of proteasomes in ischemia-reperfusion injury of organs. J Physiol Pharmacol 55:3–15, 2004. Lalu MM, Wang W, Schulz R: Peroxynitrite in myocardial ischemia-reperfusion injury. Heart Fail Rev 7:359–369, 2002. Lawen A: Apoptosis: An introduction. Bioessays 25:888–896, 2003. Li C, Jackson RM: Reactive species mechanisms of cellular hypoxia-reoxygenation injury. Amer J Physiol Cell Physiol 282:C227–241, 2002. Liaudet L, Szabo G, Szabo C: Oxidative stress and regional ischemia-reperfusion injury: The peroxynitrite-poly(ADP-ribose) polymerase connection. Coron Artery Dis 14:115– 122, 2003. McBride WH, Iwamoto KS, Syljuasen R, et al.: The role of the ubiquitin/proteasome system in cellular responses to radiation. Oncogene 22:5755–5773, 2003. Mentzer RM Jr, Lasley RD, Jessel A, et al.: Intracellular sodium hydrogen exchange inhibition and clinical myocardial protection. Ann Thorac Surg 75:S700–708, 2003. Murphy E, Cross HR, Steenbergen C: Is Na/Ca exchange during ischemia and reperfusion beneficial or detrimental? Ann NY Acad Sci 976:421–430, 2002. Rubin 5e Suggested Readings P. 4 of 97 Nieminen AL: Apoptosis and necrosis in health and disease: Role of mitochondria. Int Rev Cytol 224:29–55, 2003. Ostler EL, Wallis CV, Sheerin AN, et al.: A model for the phenotypic presentation of Werner’s syndrome. Exp Gerontol 37:285–292, 2002. Piper HM, Meuter K, Schafer C: Cellular mechanisms of ischemia-reperfusion injury. Ann Thorac Surg 75:S644–648, 2003. Rao RV, Bredesen DE: Misfolded proteins, endoplasmic reticulum stress and neurodegeneration. Curr Opin Cell Biol 16:653–662, 2004. Reid MB: Response of the ubiquitin-proteasome pathway to changes in muscle activity. Am J Physiol Regul Integr Comp Physiol 228:R1423–R1431, 2005. Rensing L, Meyer-Grahle U, Ruoff P: Biological timing and the clock metaphor: Oscillatory and hourglass mechanisms. Chronobiol Int 18:329–369, 2001. Ryazanov AG, Nefsky BS: Protein turnover plays a key role in aging. Mech Ageing Dev 123:207–213, 2002. Sack MN, Yellon DM: Insulin therapy as an adjunct to reperfusion after acute coronary ischemia: A proposed direct myocardial cell survival effect independent of metabolic modulation. J Amer Coll Cardiol 41:1404–1407, 2003. Salvemini D, Cuzzocrea S: Superoxide, superoxide dismutase and ischemic injury. Curr Opin Invest Drugs 3:886–895, 2002. Saretzki G, Von Zglinicki T: Replicative aging, telomeres, and oxidative stress. Ann NY Acad Sci 959:24–29, 2002. Sax JK, El-Deiry WS: p53 downstream targets and chemosensitivity. Cell Death Diff 10:413–417, 2003. Rubin 5e Suggested Readings P. 5 of 97 Schmidt-Ullrich RK, Dent P, Grant S, et al.: Signal transduction and cellular radiation responses. Radiat Res 153:245–257, 2000. Schultz DR, Harrington WJ Jr: Apoptosis: Programmed cell death at a molecular level. Semin Arthritis Rheum 32:345–369, 2003. Shearer MJ: Role of vitamin K and Gla proteins in the pathophysiology of osteoporosis and vascular calcification. Curr Opin Clin Nutr Metab Care 3:433–438, 2000. Sohal RS: Role of oxidative stress and protein oxidation in the aging process. Free Radic Biol Med 33:37–44, 2002. Squier TC: Oxidative stress and protein aggregation during biological aging. Exp Gerontol 36:1539–1550, 2001. Steensma DP, Timm M, Witzig TE: Flow cytometric methods for detection and quantification of apoptosis. Meth Mol Med 85:323–332, 2003. Tabner BJ, El-Agnaf OMA, German MJ, et al.: Protein aggregation, metals and oxidative stress in neurodegenerative diseases. Biochem Soc Trans 33:1082–1086, 2005. Tatar M, Bartke A, Antebi A: The endocrine regulation of aging by insulin-like signals. Science 299:1346–1351, 2003. Thompson LH, Schild D: Recombinational DNA repair and human disease. Mutat Res 509:49–78, 2002. Walter L, Miyoshi H, Leverve X, et al.: Regulation of the mitochondrial permeability transition pore by ubiquinone analogs. A progress report. Free Rad Res 36:405–412, 2002. Wymann MP, Zvelebil M. Laffargue M: Phosphoinositide 3-kinase signalling: Which way to target? Trends Pharmacol Sci 24:366–376, 2003. Rubin 5e Suggested Readings P. 6 of 97 Yoshida H: The role of Apaf-1 in programmed cell death: From worm to tumor. Cell Struct Funct 28:3–9, 2003. Yu BP, Lim BO, Sugano M: Dietary restriction downregulates free radical and lipid peroxide production: Plausible mechanism for elongation of life span. J Nutr Sci Vitaminol 48:257–264, 2002. Yuasa Y: DNA methylation in cancer and ageing. Mech Ageing Dev 123:1649–1654, 2002. Chapter 2 Books Collins T: Leukocyte recruitment, endothelial cell adhesion molecules, and transcriptional control: Insights for drug discovery. Philadelphia: Kluwer, 2001. Cronstein BN, Weissmann G, Koch A, et al.: Inflammation. Philadelphia: Kluwer, 2004. Gallin JI, Synderman R, Fearon DT, et al.: Inflammation: Basic oprinciples and clinical correlates. Philadelphia: Lippincott Williams & Wilkins, 1999. Gorski A, Krotkiewski H, Zimecki M: Inflammation. Philadelphia: Kluwer, 2001. Honn KV, Marnett LJ, Nigam S, et al.: Eicosanoids and other bioactive lipids in cancer, inflammation, and radiation injury. Philadelphia: Kluwer, 2003. Ley K: Physiology of inflammation. Bethesda, MD: American Physiological Society, 2001. Pearson JD: Vascular adhesion molecules and inflammation. New York: Springer- Verlag, 2002. Rubin 5e Suggested Readings P. 7 of 97 Salvemini D, Billiar TM, Vodovotz Y: Nitric oxide and inflammation. Boston: Birkhauser, 2001. Van Eden W: Heat shock proteins and inflammation research. Boston: Birkhauser, 2004. Whicher JT, Evans SW: Biochemistry of inflammation. Philadelphia: Kluwer Academic/Plenum, 1992. Winyard PD, Evans BC: Free radicals in inflammation. Boston: Birkhauser, 2004. Yazici Z, Folco GC, Drazen JM, et al.: Advances in prostaglandin, leukotriene and other bioactive lipid research: Basic science and clinical applications. Philadelphia: Kluwer, 2003. Review Articles Baggiolini M: Chemokines in pathology and medicine. J Intern Med 250:91, 2001. Biedermann BC: Vascular endothelium: Checkpoint for inflammation and immunity. News Physiol Sci 16:84, 2001. Booth JW, Trimble WS, Grinstein S: Membrane dynamics in phagocytosis. Semin Immunol 13:357, 2001. Bornstein P, Sage EH: Matricellular proteins: Extracellular modulators of cell function. Curr Opin Cell Biol 14:608, 2002. Buckley CD, Pilling D, Lord JM, et al.: Fibroblasts regulate the switch from acute resolving to chronic persistent inflammation. Trends Immunol 22:199, 2001. Co DO, Hogana LH , Il-Kim S, et al.: T cell contributions to the different phases of granuloma formation. Immunol Letts 92:135, 2004. Rubin 5e Suggested Readings P. 8 of 97 De Maio A, Torres MB, Reeves RH: Genetic determinant influencing the response to injury, inflammation and sepsis.