Name Class Date 33.1 The Circulatory System Lesson Objectives Identify the functions of the human circulatory system. Describe the structure of the heart and explain how it pumps blood through the body. Name three types of blood vessels in the circulatory system. Lesson Summary Functions of the Circulatory System The circulatory system transports oxygen, nutrients, and other substances throughout the body, and removes wastes from tissues. The Heart The muscle layer of the heart is the myocardium. Its powerful contractions pump blood through the circulatory system. The human heart has four chambers. A wall called the septum separates the right side of the heart from the left side. On each side of the septum are an upper and lower chamber. ▶ Each upper chamber, or atrium (plural: atria), receives blood from the body; each lower chamber, or ventricle, pumps blood out of the heart. ▶ Flaps of connective tissue called valves are located between the atria and the ventricles and between the ventricles and blood vessels leaving the heart. The valves open and close to keep blood moving in one direction. The heart pumps blood through two pathways: ▶ Pulmonary circulation pumps blood from the heart to the lungs and back to the heart again. Blood picks up oxygen and releases carbon dioxide in the lungs. ▶ Systemic circulation pumps blood from the heart to the rest of the body. Cells absorb much of the oxygen and load the blood with carbon dioxide. The heart muscle beats in an orderly and coordinated way. A small group of cardiac muscle fibers, the sinoatrial node (SA node), is also called the pacemaker. When the pacemaker fires, an electrical impulse causes the atria to contract. Another group of muscle fibers, the atrioventricular node (AV node), causes the ventricles to contract. The nervous system influences the SA node, increasing or decreasing heart rate to meet the body’s needs. Blood Vessels Blood flows through the circulatory system in blood vessels: ▶ Arteries are large vessels that carry blood away from the heart to the tissues of the body. Except for the pulmonary arteries, all arteries carry oxygen-rich blood. ▶ Capillaries are the smallest vessels. Their thin walls allow oxygen and nutrients to pass from blood into tissues and wastes to move from tissues into blood. ▶ Veins return blood to the heart. Many have valves that prevent backflow. The contractions of the heart produce a wave of fluid pressure in the arteries, known as blood pressure. Without that pressure, blood would stop flowing through the body. The body regulates blood pressure through actions of the brain and the kidneys. Lesson 33.1 • Workbook A • Copyright © by Pearson Education, Inc., or its affi liates. All Rights Reserved. 514 013368718X_CH33_513-528.indd 2 1/5/09 12:48:24 PM Name Class Date Functions of the Circulatory System 1. Why do animals with millions of cells “need” a circulatory system while animals with few cells can do without one? If all cells are in direct contact with the environment, diffusion and active transport can provide nutrients and oxygen and remove wastes. Large, multicellular organisms have cells that are not in direct contact with the environment. A circulatory system is required to serve those functions. 2. Marie lives in a large city. She is disabled and cannot leave her home. Everything she needs must be delivered to her, and all her garbage must be hauled away. Compare how the streets and highways of the city supply Marie’s needs with how the circulatory system supplies the needs of individual cells of the human body. Marie’s food, medicines, and other supplies are brought to her door by delivery people who travel along streets and highways. Garbage collectors use those same streets and highways to collect and haul away her trash. The same thing happens in the body. Delivery people (blood cells) travel along streets and highways (arteries and veins). They deliver supplies like oxygen and nutrients. They also collect waste prod- ucts like carbon dioxide and haul them away. The Heart 3. Complete the table. Circulation Pathway Side of Heart Destination After Blood Change Pumping Leaving Heart Pulmonary Right Lungs Oxygen poor to oxygen rich Systemic Left Body Oxygen rich to oxygen poor Lesson 33.1 • Workbook A • Copyright © by Pearson Education, Inc., or its affi liates. All Rights Reserved. 515 013368718X_CH33_513-528.indd 3 1/5/09 12:48:26 PM Name Class Date 4. Label the diagram at the points indicated to show the structures of the human circulatory system. Add arrows to show the direction of blood flow. Capillaries of head and arms a. Superior b. Aorta vena cava c. Pulmonary artery Pulmonary Capillaries of f. Capillaries of e. vein right d. lung left lung Inferior g. vena cava Capillaries of abdominal organs and legs 5. Complete the flowchart to show the actions that keep the heart beating in an orderly way. The SA node fires Electrical impulse Impulse from the spreads through SA node is picked the atria and the up by the AV node atria contract Impulse is AV node produces Ventricles contract delayed while the impulses that and pump blood atria contract spread through out of the heart and pump blood the ventricles to the ventricles Lesson 33.1 • Workbook A • Copyright © by Pearson Education, Inc., or its affi liates. All Rights Reserved. 516 013368718X_CH33_513-528.indd 4 1/5/09 12:48:29 PM Name Class Date Blood Vessels 6. As blood flows through the body, it passes through three types of blood vessels. Complete the table by naming each type and describing its structure and function. Blood vessels Structure Function Arteries Thick, elastic walls containing Carry blood from the heart to the connective tissue, smooth tissues of the body muscle, and endothelium Capillaries Smallest blood vessels; Allow oxygen and nutrients to diffuse extremely thin walls from blood into tissues, and wastes to move from tissues into blood Veins Large vessels; many contain Carry blood toward the heart valves to ensure that blood flows in one direction 7. Complete the feedback diagram to show how the nervous system regulates blood pressure. Neurotransmitters Neurotransmitters relax smooth muscles cause smooth muscles in in blood vessel walls. vessel walls to contract. Nervous System Blood pressure falls. Blood pressure rises 8. The left side of the heart is larger and more muscular than the right side. Also, artery walls are thicker than those of veins. Explain how those differences in structure are important to function. SAMPLE ANSWER: The left side of the heart must pump blood through the entire body. It has to be stronger than the right side, which only pumps blood to the lungs. Arteries carry blood away from the heart. They must be stronger and more flexible than veins to withstand the pressure of the pumping heart. Lesson 33.1 • Workbook A • Copyright © by Pearson Education, Inc., or its affi liates. All Rights Reserved. 517 013368718X_CH33_513-528.indd 5 1/5/09 12:48:31 PM Name Class Date 33.2 Blood and the Lymphatic System Explain the functions of blood plasma, red blood cells, white blood cells, and platelets. Describe the role of the lymphatic system. List three common circulatory diseases. Describe the connection between cholesterol and circulatory disease. Lesson Summary Blood Blood has four main components: ▶ Plasma is a straw-colored fluid. It is about 90 percent water and 10 percent dissolved gases, salts, nutrients, enzymes, hormones, waste products, plasma proteins, cholesterol, and other important compounds. Parts of plasma help control body temperature, transport substances, and fight infection. Plasma proteins are involved in blood clotting. ▶ Red blood cells transport oxygen. Blood gets its red color from the iron in hemoglobin, a protein that binds oxygen in the lungs and releases it in the capillaries. ▶ White blood cells guard against infection, fight parasites, and attack bacteria. ▶ Platelets are cell fragments involved in blood clotting. The Lymphatic System The lymphatic system is a network of vessels, nodes, and organs that collects the fluid that leaves the capillaries, “screens” it for microorganisms, and returns it to the circulatory system. ▶ Lymph is fluid that consists of blood components that have moved through the walls of capillaries. ▶ Lymph vessels transport materials and lymph nodes act as filters, trapping microorganisms, stray cancer cells, and debris. Circulatory System Diseases Three common and serious diseases of the circulatory system are: ▶ Heart disease: A leading cause of heart disease is atherosclerosis, a condition in which fatty deposits called plaque build up in artery walls and eventually cause the arteries to stiffen. A heart attack occurs as heart muscle cells become damaged. ▶ Stroke: A clot that blocks a blood vessel in the brain may cause a stroke, which is the sudden death of brain cells when their blood supply is interrupted. A stroke can also occur if a weak vessel breaks and causes bleeding in the brain. ▶ High blood pressure, or hypertension, is usually defined as blood pressure higher than 140/90. Uncontrolled high blood pressure can damage the heart and blood vessels. It can also lead to heart attack, stroke, and kidney damage. Understanding Circulatory Disease Cholesterol is a lipid that is part of animal cell membranes. It is transported in the blood primarily by two types of lipoproteins: low-density lipoprotein (LDL) and high-density lipoprotein (HDL). The liver manufactures cholesterol, but it also comes from animal product foods. High cholesterol levels, along with other risk factors, lead to atherosclerosis and higher risk of heart attack. Lesson 33.2 • Workbook A • Copyright © by Pearson Education, Inc., or its affi liates. All Rights Reserved. 518 013368718X_CH33_513-528.indd 6 1/5/09 12:48:34 PM Name Class Date Blood For Questions 1–5, write True if the statement is true.