Minnesota Department of Health, Chemicals of High Concern List, 2019 Persistent, Bioaccumulative, Toxic (PBT) or very Persistent, very High Production CAS Bioaccumulative Use Example(s) and/or Volume (HPV) Number Chemical Name Health Endpoint(s) (vPvB) Source(s) Chemical Class Chemical1 Maine (CA Prop 65; IARC; IRIS; NTP Wood and textiles finishes, Cancer, Respiratory 11th ROC); WA Appen1; WA CHCC; disinfection, tissue 50-00-0 Formaldehyde x system, Eye irritant Minnesota HRV; Minnesota RAA preservative Gastrointestinal Minnesota HRL Contaminant 50-00-0 Formaldehyde (in water) system EU Category 1 Endocrine disruptor pesticide 50-29-3 DDT, technical, p,p'DDT Endocrine system Maine (CA Prop 65; IARC; IRIS; NTP PAH (chem-class) 11th ROC; OSPAR Chemicals of Concern; EuC Endocrine Disruptor Cancer, Endocrine Priority List; EPA Final PBT Rule for 50-32-8 Benzo(a)pyrene x x system TRI; EPA Priority PBT); Oregon P3 List; WA Appen1; Minnesota HRV WA Appen1; Minnesota HRL Dyes and diaminophenol mfg, wood preservation, 51-28-5 2,4-Dinitrophenol Eyes pesticide, pharmaceutical Maine (CA Prop 65; IARC; NTP 11th Preparation of amino resins, 51-79-6 Urethane (Ethyl carbamate) Cancer, Development ROC); WA Appen1 solubilizer, chemical intermediate Maine (CA Prop 65; IARC; IRIS; NTP Research; PAH (chem-class) 11th ROC; EPA Final PBT Rule for 53-70-3 Dibenzo(a,h)anthracene Cancer x TRI; WA PBT List; OSPAR Chemicals of Concern); WA Appen1; Oregon P3 List Maine (CA Prop 65; NTP 11th ROC); Research 53-96-3 2-Acetylaminofluorene Cancer WA Appen1 Maine (CA Prop 65; IARC; IRIS; NTP Lubricant, antioxidant, 55-18-5 N-Nitrosodiethylamine Cancer 11th ROC); WA Appen1 plastics stabilizer Maine (CA Prop 65; IRIS; NTP 11th Pesticide (EPA reg. ROC); WA Appen1; Minnesota HRL cancelled), fire reduction, 56-23-5 Carbon tetrachloride Cancer x solvent, fumigant, dry cleaning Environmental Surveillance and Assessment Section [email protected] 651-201-4899 Minnesota Department of Health, Chemicals of High Concern List, 2019 Persistent, Bioaccumulative, Toxic (PBT) or very Persistent, very High Production CAS Bioaccumulative Use Example(s) and/or Volume (HPV) Number Chemical Name Health Endpoint(s) (vPvB) Source(s) Chemical Class Chemical1 Maine (EuC Endocrine Disruptor Antimicrobials, slimasides Priority List; EU PBT List; OSPAR Chemicals of Concern; ECHA 56-35-9 Bis(tributyltin)oxide (TBTO) Endocrine system x Substances of Very High Concern; Canada PBiT); WA Appen1; Oregon P3 List Maine (CA Prop 65; EuC Endocrine Research Disruptor Priority List; EPA Final Cancer, Endocrine 56-49-5 3-Methylcholanthrene x PBT Rule for TRI; WA PBT List; system OSPAR Chemicals of Concern); WA Appen1 Maine (CA Prop 65; IRIS; NTP 11th Research; PAH (chem-class) ROC; EPA Final PBT Rule for TRI; 56-55-3 Benzo(a)anthracene Cancer x OSPAR Chemicals of Concern); WA Appen1; Oregon P3 List NTP Solvent, dye assistant, phase 56-93-9 Trimethylbenzylammonium chloride Systemic Toxicity x transfer catalyst 2,4,11,13- Maine (Canada PBiT); WA Appen1 Biocide Tetraazatetradecanediimidamide, 56-95-1 x N,N''-bis(4-chlorophenyl)-3,12- diimino-, diacetate IRIS; WA Appen1; Minnesota HRL Electroplating, chemicals Nervous system, 57-12-5 Cyanide, free mfg, naturally occurring in Thyroid, Weight Loss some foods Maine (CA Prop 65; NTP 11th ROC); Rocket fuel or propellant, 57-14-7 1,1-Dimethylhydrazine (UDMH) Cancer WA Appen1 photography, plant growth regulators HSDB; IRIS; WA Appen1 Pesticide, pharmaceutical 57-24-9 Strychnine Nervous system Maine (CA Prop 65; OSPAR Pesticide (EPA reg. Chemicals of Concern; EuC cancelled) Endocrine Disruptor Priority List; Cancer, Endocrine 57-74-9 Chlordane x EPA Final PBT Rule for TRI; TRI PBT system Chemical List; EPA Priority PBT; WA PBT List); WA Appen1 Environmental Surveillance and Assessment Section [email protected] 651-201-4899 Minnesota Department of Health, Chemicals of High Concern List, 2019 Persistent, Bioaccumulative, Toxic (PBT) or very Persistent, very High Production CAS Bioaccumulative Use Example(s) and/or Volume (HPV) Number Chemical Name Health Endpoint(s) (vPvB) Source(s) Chemical Class Chemical1 Maine (CA Prop 65; Canada PBiT; Antimicrobial NTP 11th ROC; OSPAR Chemicals of Concern; EuC Endocrine Disruptor Hexachlorocyclohexane, gamma-, Cancer; Endocrine 58-89-9 x Priority List; NWM Priority (Lindane) system Chemicals; OSPAR Chemicals of Concern); WA Appen1; Oregon P3 List 58-90-2 2,3,4,6-Tetrachlorophenol Liver IRIS; WA Appen1 Pesticide, preservative Maine (CA Prop 65; NTP 11th ROC); Solvent, chemical synthesis 59-89-2 N-Nitrosomorpholine Cancer WA Appen1 Maine (CA Prop 65); WA Appen1 Dye 60-09-3 p-Aminoazobenzene (Aniline Yellow) Cancer Maine (CA Prop 65; NTP 11th ROC); pH indicators - spot tests 60-11-7 4-Dimethylaminoazobenzene Cancer WA Appen1 OECD - SIDS/SIAR Dyestuff, chemical Eyes, Cardiovascular 60-24-2 2-Mercaptoethanol intermediate, chemical mfg x system, Liver, Skin Maine (CA Prop 65); WA Appen1 Solvent, plasticizer, 60-35-5 Acetamide Cancer stabilizer, humectant 60-51-5 Dimethoate Nervous system IRIS; WA Appen1 Pesticide Maine (CA Prop 65; IRIS; EPA Pesticide (not EPA Cancer, Development, Priority PBT; WA PBT List; OSPAR registered) Endocrine system, Chemicals of Concern); WA 60-57-1 Dieldrin x Immune system, Liver, Appen1; Oregon P3 List; Minnesota Nervous system HRL Maine (CA Prop 65; NTP 11th ROC; Pesticide Cancer, Endocrine 61-82-5 Amitrole EuC Endocrine Disruptor Priority system List); WA Appen1 62-38-4 Phenylmercuric Acetate Kidney IRIS; WA Appen1 Preservative Maine (CA Prop 65; NTP 11th ROC); Research, catalyst in 62-50-0 Ethyl methanesulfonate Cancer WA Appen1 chemical mfg Maine (CA Prop 65; IRIS); WA Chemical mfg, (polyurethane Appen1; WA CHCC foam, varnishes, perfumes, 62-53-3 Aniline Cancer x printing inks) Environmental Surveillance and Assessment Section [email protected] 651-201-4899 Minnesota Department of Health, Chemicals of High Concern List, 2019 Persistent, Bioaccumulative, Toxic (PBT) or very Persistent, very High Production CAS Bioaccumulative Use Example(s) and/or Volume (HPV) Number Chemical Name Health Endpoint(s) (vPvB) Source(s) Chemical Class Chemical1 Maine (CA Prop 65; NTP 11th ROC); Inorganic chemical analysis, WA Appen1 motor fuel stabilizer, accelerator in vulcanization 62-55-5 Thioacetamide Cancer of buna rubber; former uses as solvent in leather, textile, paper industries Maine (CA Prop 65; NTP 11th ROC); Fire retardant, hair dyes, 62-56-6 Thiourea Cancer WA Appen1; WA CHCC boiler water treatment, x photography chemicals Cancer, Nervous Maine (CA Prop 65; IRIS); WA Pesticide 62-73-7 DDVP (Dichlorvos) system Appen1; Minnesota HRV Maine (CA Prop 65); WA Appen1 Pesticide 62-74-8 Sodium fluoroacetate Reproduction Maine (CA Prop 65; IARC; IRIS; NTP Industrial solvent, 62-75-9 N-Nitrosodimethylamine Cancer 11th ROC); WA Appen1 antioxidant Maine (EuC Endocrine Disruptor Pesticide 63-25-2 Carbaryl Endocrine system Priority List); WA Appen1 Maine (CA Prop 65; IARC); WA Solvent, fuel, cosmetics, Appen1 drinks, antifreeze, 64-17-5 Ethanol Cancer, Development x detergents, hair spray, fragrances, lotions HSDB; WA Appen1 Pesticide, acidulating agent 64-18-6 Formic acid Eyes x in dyeing, solvent Maine (CA Prop 65; IARC; NTP 11th Ethylating agent, chemical 64-67-5 Diethyl sulfate Cancer ROC); WA Appen1 intermediate in dye mfg Maine (CA Prop 65; IARC; NTP 11th Research, catalyst 66-27-3 Methyl methanesulfonate Cancer ROC); WA Appen1 Cal Prop 65 solvent, antifreeze, fuel, (reproductive/developmental) chemical production, paint, 67-56-1 methanol Development adhesive, detergent, home x cleaners Maine (CA Prop 65; IRIS; NTP 11th Solvent Cancer, Development, ROC); WA Appen1; Minnesota HRL; 67-66-3 Chloroform Immune system, x Minnesota HRV Reproduction Environmental Surveillance and Assessment Section [email protected] 651-201-4899 Minnesota Department of Health, Chemicals of High Concern List, 2019 Persistent, Bioaccumulative, Toxic (PBT) or very Persistent, very High Production CAS Bioaccumulative Use Example(s) and/or Volume (HPV) Number Chemical Name Health Endpoint(s) (vPvB) Source(s) Chemical Class Chemical1 Maine (CA Prop 65; NTP 11th ROC; Organic chemical synthesis, NWM Priority Chemicals; OSPAR pyrotechnics, solvent 67-72-1 Hexachloroethane Cancer x Chemicals of Concern); WA Appen1 OECD - SIDS/SIAR; WA Appen1; Solvents, chemical 68-12-2 N,N-dimethylformamide Liver x Minnesota HRV intermediates, paints N-Methyl-N'-nitro-N- Maine (CA Prop 65; IARC; NTP 11th Research 70-25-7 Cancer nitrosoguanidine ROC); WA Appen1 Maine (OSPAR Chemicals of Antibacterial, disinfectant, phenol, 2,2'-methylenebis[3,4,6- 70-30-4 x Concern); WA Appen1; Oregon P3 pesticide (EPA reg. trichloro- List cancelled) Maine (CA Prop 65; IARC; EU Inks, rubbers, lacquers, paint Blood, Cancer, Carcinogen; IRIS; NTP 11th ROC); remover, gasoline additive Development, 71-43-2 Benzene WA Appen1; WA CHCC; Minnesota x Immune system, HRL; Minnesota HRV Reproduction ECHA Substances of Very High bleaching agent and drier for 71-48-7 Cobalt(II) diacetate Reproduction, Cancer Concern lacquers, varnishes x Maine (CA Prop 65; WA PBT List; Pesticide (EPA reg. OSPAR Chemicals of Concern); WA cancelled) 72-20-8 Endrin Development x Appen1; Oregon P3 List Maine ( EuC Endocrine Disruptor Pesticide (EPA reg. Priority List; EPA Final PBT Rule for cancelled) TRI; TRI PBT Chemical List; NWM Priority Chemicals; OSPAR 72-43-5 Methoxychlor Endocrine system x Chemicals of Concern; OSPAR Chemicals for Priority Action); WA Appen1 Maine (CA Prop 65; IRIS;