Order: (888)-282-5810 (Phone) (818)-707-0392 (Fax) [email protected] Web: www.Abiocode.com ADCY1 (N) Antibody, Rabbit Polyclonal Cat#: R0758-1 Lot#: Refer to vial Quantity: 100 ul Application: WB, IP Predicted | Observed MW: 123 | 130-180 kDa Uniprot ID: Q08828 Background: Adenylate cyclase type 1 (ADCY1) is a multi-pass membrane protein that belongs to the adenylyl cyclase class-4/guanylyl cyclase family. ADCY1 is the neural-specific calmodulin-sensitive adenylyl cyclase. Adenylyl cyclases are a group of enzymes that convert adenosine-5'-triphosphate (ATP) into 3',5'-adenosine monophosphate (cAMP) and pyrophosphate. ADCY1 may be involved in regulatory processes in the central nervous system. It may play a role in memory acquisition and learning. Other Names: Adenylate cyclase type 1, ATP pyrophosphate-lyase 1, Adenylate cyclase type I, Adenylyl cyclase 1, Ca(2+)/calmodulin-activated adenylyl cyclase Source and Purity: Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the N-terminal region of human ADCY1. Antibodies were purified by affinity purification using immunogen. Storage Buffer and Condition: Supplied in 1 x PBS (pH 7.4), 100 ug/ml BSA, 40% Glycerol, 0.01% NaN3. Store at -20 °C. Stable for 6 months from date of receipt. Species Specificity: Human, Mouse Tested Applications: WB: 1:500-1:2,000 (detect endogenous protein*) IP: 1:100-1:200 *: The apparent protein size on WB may be different from the calculated M.W. due to modifications. For research use only. Not for therapeutic or diagnostic purposes. Abiocode, Inc., 29397 Agoura Rd., Ste 106, Agoura Hills, CA 91301 Order: (888)-282-5810 (Phone) (818)-707-0392 (Fax) [email protected] Web: www.Abiocode.com Product Data: IP A B -1 kDa IgG R0758 175 ADCY1 kDa 175 ADCY1 80 80 58 58 46 46 WB: R0758-1 WB: R0758-1 Fig 1. A) Western blot of total cell extracts from mouse brain, using anti-ADCY1 (N) (R0758-1) at RT for 2 h. B) Total extracts from mouse brain were immunoprecipitated with IgG or anti-ADCY1 (N) (R0758-1); followed by WB with the same Ab. For research use only. Not for therapeutic or diagnostic purposes. Abiocode, Inc., 29397 Agoura Rd., Ste 106, Agoura Hills, CA 91301.