http:/chicagoacs.org MAY• 2004 THE NINETY-THIRD PRESENTATION OF THE WILLARD GIBBS MEDAL (Founded by William A. Converse) to PROFESSOR RONALD BRESLOW sponsored by the CHICAGO SECTION AMERICAN CHEMICAL SOCIETY FRIDAY, MAY 21, 2004 North Shore Lights at The iation for a nametag , and your check. Acceptance of the Award Hotel Moraine Be sure to include your address. 700 North Sheridan Road Tables fo r ten are availab le. If you Highwood, Illinois would like a table for a group, please 847-433-6366 put the ir names on a separate sheet and include it with your registration. DIRECTIONS TO THE MEETING From the North or South: Take 1-294 (continued on page 2) (the TriState Tollway) to Route 22. Exit east, take it to Route 41 (Skokie Hwy). AWARD CEREMONY 8:30 P.M. Turn north to the next exit, Old Elm. Go east on Old Elm to Sheridan Road Oust The Willard Gibbs Medal across some railroad tracks) . Turn right/south for 3/4 mile. The hotel is on Milt Levenberg, Chair the right. Chicago Section, ACS From Downtown: Take the Kennedy Introduction of the Medalist Expressway north. At the split , follow the Edens Expressway , which turns Madeleine Jacobs Executive Director & CEO, ACS into Skokie Highway past Lake Cook Dr. Ronald Breslow Road. Continue north to Old Elm Road. Presentation of the Medal Samuel Latham Mitchill Professor of Turn right/east on Old Elm and follow Chemistry and University Professor the directions above to the hotel. Dr. Charles P. Casey Department of Chemistry President, ACS Columbia University Parking: Free New York, NY RECEPTION 6:00-7:00 P.M. Citation: For seminal work in the (continued on page 2, Column 1) development of anti-aromaticity; for NOTICE TO ILLINOIS DINNER 7:00 P.M. pioneering work in bioorganic chem­ istry; for inspiring the creation of the TEACHERS field of biomimetic chemistry, and for Dinner reservations are required. The Chicago Section-ACS is an ISBE Please send in the form enclosed in research in organic chemistry leading to advances in medical applications. provider for professional development this issue to the Chicago Section office units for Illinois teachers. Teachers who at 7173 N. Austin, Niles, IL 60614 with registerfor this month's meeting will have your menu choice, your name and affil- the opportunityto earn up to 4 CPDU's. 5/04 2 ACCEPTANCE ADDRESS He is a member of the U.S. National (continued from page 1, Column 2) Academy of Sciences (Chairman of the Tickets will be sent to you by mail. On­ "Progress on a New Approach to Chemistry Division 1974-77), of the line registrants may pick up their tickets Cancer Chemotherapy" American Academy of Arts and Sci­ at the door. No refunds will be made ences and of the American Philosophi­ after noon Tuesday May 18 for cancel­ Abstract: We have developed a group cal S~ciety (member of the Council , lations or no-shows. of potent molecules that acc?mplish a 1987-92), as well as other scientific The cost of the dinner is $40 for mem­ number of important goals in cancer societies including the New York bers and guests. The cost to non-mem­ therapy with a wide range of cancer Academy of Sciences. He is a Foreign be rs is $42. The cost for students, types. 1) The cancer cells cease growth. Fellow of the Indian National Science unemployed members and retirees is 2) They can differentiate into normal Academy, an Honorary Member of the $20. Note: Professors must make stu­ non-cancerous cells. 3) In some cases Korean Chemical Society, an Honorary dent reservations. they undergo apoptosis , programmed Member of the Royal Society of Chem­ Seating will be available after the din­ cell death. The compounds do not show istry of Great Britain, a Foreign Member ner for people not attending the dinner significant toxicity, are orally active, and of the Royal Society of Britain, a Fellow but interested in hearing the speaker. the lead compound has successfully fin­ of the World Innovation Foundation, an ished phase 1 and 2 clinical trials. The Honorary Member of the Chemical THE MENU: Lobster Bisque ; Salad intellectual path that led to the potent Society of Japan, and an Honorary Pro­ Maison with a field of greens, peppered compounds will be described, as well as fessor of the University of Science and orange , and tomato ; Main course the evidence on how they work and the Technology of China. choice of either Filet Mignon accented results of animal and human trials. He has been the Chairman of the by Grilled Jumbo Shrimp or Bro iled Board of Scientific Advisors of the Norwegian Salmon dressed with Lemon THE MEDALIST Alfred P. Sloan Foundation , and a Lime Herb Sauce; Duchess Potato; member of the Board of Trustees of Steamed Vegetable Medley. A vegetari­ Ronald Breslow was born in Rahway, Rockefeller University. He is on the Edi­ an entree of a Portabello Mushroom New Jersey on March 14, 1931. He torial Board of a number of scientific Tower atop Linguine Pasta adorned received his undergraduate and gradu­ journals, and has held over 200 named with red and green bel l peppers, ate training at Harvard Universi~y , and visiting Professorships. onions, and fresh spinach is available where he did his Ph.D. research with His major scientific awards include t~e on request. Dessert is a Flourless Professor R.B. Woodward. He then American Chemical Society Award in Chocolate Torte . Wine will be served spent a year in Cambridge, England as Pure Chemistry (1966), the Fresenius with dinner. a postdoctoral fellow with Lord Todd, Award of Phi Lambda Upsilon (1966), and came to Columbia University in the Baekeland Medal (1969), the Cen­ REGISTERTO ATTEND 1956 as Instructor in Chemistry. He is tenary Medal (1972) , the Harrison now the Samuel Latham Mitchill Profes­ Howe Award (1974), the Remsen Prize MONTHLYSECTION MEETINGS sor of Chemistry at Columbia and one (1977), the Roussel Prize in Steroids of twelve University Professors, and a (1978), the James Flack Norris Prize in ONLINE former Chairman of the Department. Physical Organic Chemistry of the at Professor Breslow's research interests American Chemical Society (1980), the www.ChicagoACS.org can be described generally as involving Richards Medal (1984) , the Arthur C. the design and synthesis of ~ew Cope Award (1987), the Kenner Award In This Issue molecules with interesting properties , (1988), the Nichols Medal (1989), the and the study of these properties. Exam­ National Academy of Sciences Award J'eatures ples include the cyclopropenyl cation, in Chemistry (1989), the Allan Day 1 Gibbs Award Ceremony & Dinner the simplest aromatic system and t~e Award (1990) , the Paracelsus Award 2 Gibbs Medalist first aromatic compound prepared with and Medal of the Swiss Chemical Soci­ 3 Volunteers Needed for ACS other than six electrons in a ring. ety (1990), and the U.S. National Medal Booth/IL State Fair His work establishing the phe­ of Science (1991). He was named one 4 Online Career Management Tools nomenon of anti-aromaticity has of the top 75 contributors to the chemi­ 5 Willard Gibbs Award History involved the synthesis of novel cal enterprise in the past 75 years by 1 wee Meeting molecules, as well as their study. Even Chemical & Engineering News (1997), 8 ALMA Disting uished Service in work on purely mechanistic ques­ and won the Priestley Medal (1999). In Award tions such as his discovery of the 2000 he won the New York City 8 Safety Publications chemical mechanism used by thiamine Mayor's Award in Science and in 2002 8 Death Notice of Dr. John Pople (vitamin B-1) in biochemical reactions , he has received the ACS Bader Award 9 Section's Affiliate Membership the synthesis and study of novel in Bioorganic or Bioinorganic Chemistry Form molecules played an important role. and the Esselen Award for Chemistry in 10 Leadership Initiative Sc ience Although he continues his interest in the Public Interest. In 2003 he received Education unusual conjugated systems, his major the Robert Welch Award in Chemistry. 11 Gibbs Dinner Reservation Form emphasis in recent years has been on He has also received the Mark Van the synthesis and study of ~olecul~s Doren Medal of Columbia University In 'Every Issue that imitate enzymatic reactions. This · and the Columbia University Great 1 Notice to Illinois Teachers work has included the development of Teacher Award . He was President ­ 3 ChemShorts for Kids remote functionalization reactions and Elect of the American Chemical Society 6 ALMA e-News the development of artificial enzymes. (1995), was ACS President (1996)., and 6 Free T-Shirts Recently he has developed a n~w was ACS Immediate Past President 7 wee Column: This Month­ group of cytodifferentiating agents with (1997) Ka Yee Lee potential use in cancer chemo~he~apy. 11 Ad Index He is the author of over 400 publications. 12 Calendar 5/04 3 exhibit.com . This experiment is on May, 2004 Vol. 91, No. 5. Published · page 25 of the Teacher 's Guide. 'CHEMSHORTS'' by the Chicago Section of The Ameri­ . Strange Matter is a traveling exhibition Iii.: can Chemical Society, Editorial Staff: developed by the Ontario Science Cen­ Cherlyn Bradley , Editor , and Fran tre and presented by the Materials The Elementary Education Committee Kravitz; Avrom Litin , Publications Research Soc iety with the support of of the Chicago Section ACS presents Business Manager. Address: 7173 the National Science Foundation. this column. They hope that it will reach North Austin , Niles , Illinois 60714; young children and help increase sci­ 847/647-8405. Subscr iption rates: Written by KATHLEEN CARRADO ence literacy.