Mathematical Biosciences Institute 2012-2013 ANNUAL REPORT Mathematical Neuroscience MBI receives major funding from the National Science Foundation Division of Mathematical Sciences and is supported by The Ohio State University. 2012Mathematical Biosciences Institute adheres to the AA/EOE guidelines. Message from the Director In 2012-13 MBI returned to the topic of its first annual program: Mathematical Neuroscience. The program emphasized progress that had been made in the past few years and was a great success, mainly due to the efforts of the program organizers: Carmen Canavier, John Rinzel, Steven J. Schiff, Eric Shea-Brown, and Murray Sherman. MBI’s missions include Math to Bio and Bio to Math. The first mission emphasizes the many ways that the mathematical sciences are used to clarify issues in the life sciences and the second emphasizes the ways that questions in biology are pushing developments in the mathematical sciences. The six MBI Current Topic Workshops that were held this year illustrated both of these missions with special emphasis on Bio to Math. There were two workshops on mathematical challenges spawned by models in different fields (bio-fluid dynamics and visualization) and one on statistical challenges (Statistics of Time Warping and Phase Variation). This year also saw MBI produce two milestone meetings: the MBI Tenth Anniversary Meeting (Math Biology: Looking at the Future) and The Keyfitz Centennial Symposium on Mathematical Demography. I want to point especially to the eleven spectacular talks at the tenth anniversary meeting, which can be viewed on our website. In addition, MBI organized successful three-part undergraduate research programs in summer 2012 and summer 2013. This innovative program begins with a two-week summer school for the 15 selected students. It is followed by an eight-week distributed REU, where the students divide into small groups and travel to six of our institute partners for mentoring. The program ends with a one-week Capstone Conference at MBI. At the Capstone Conference, 30-40 students who participated in math biology REU type summer programs around the country join our MBI REU students for a week of talks, posters, and special events (including a very popular grad school fair). In summer 2013, MBI continued its summer graduate program in cooperation with CAMBAM and NIMBioS. This year’s program was on Connecting Biological Data with Mathematical Models and was held at NIMBioS. MBI is about people: from our excellent staff members who make the institute work to the participants who attend our events. This year, Mathematical Biosciences Institute MBI supported 18 postdoctoral fellows who were mentored by 30-40 researchers, many at our institute partners (MBI now has more www.mbi.osu.edu | The Ohio State University | Jennings Hall 3rd Floor, 1735 Neil Ave. | Columbus, OH 43210 | 614-292-3648 than 50 IPs). During the past few years MBI has developed several innovative programs to enable more people to take advantage of MBI programming. Specifically I want to point to MBI Early Career Awards (which enable untenured tenure-track faculty to spend 3-9 months at MBI) and the MBI Conference Awards (which are best presentation prizes that provide support for each winner to attend one MBI workshop of his or her choice and are offered at conferences with a large number of women or underrepresented minority participants). MBI granted five Early Career Awards and four Conference Awards this year. Many wonder who generates MBI programs. Some are suggested by the MBI Directors, but almost all are not. The MBI Board of Trustees, the MBI Scientific Advisory Committee, the MBI Local Scientific Advisory Committee, and attendees at the annual MBI Institute Partner Meeting are all involved in program selection. The community also suggests topics for many of our workshops, and we are delighted to receive these suggestions. If you have an idea for a meeting or indeed some different way that MBI can help stimulate research at the interface between the mathematical and life sciences, please let us know. Marty Golubitsky - Director Tablecurrent of topic Contents workshops Table of Contents Current Topic Workshops MBI BioSciences Problem-Solving Workshop (PSW@MBI) 72 2012 Workshop for Young Researchers in Mathematical Biology 73-77 About MBI MBI 10th Anniversary Math Biology: Looking at the Future 78-80 MBI Mission 1 CTW: Mathematical and Computational Challenges in Cilia- and Flagella-Induced Fluid Dynamics 81-85 Institute Partners 2 CTW: Statistics of Time Warpings and Phase Variations 86-93 Directors 3-4 CTW: Mathematical Challenges in Biomolecular/Biomedical Staff 5-6 Imaging and Visualization 94-104 Postdoctoral Fellows 7-11 The Keyfitz Centennial Symposium on Mathematical Demography 105-111 Board of Trustees 12 Committees 13-15 Visiting Lecturer Program 16-17 Summer Programs Visitors 18-19 Undergraduate Research Program 112-113 Course Release 19 Joint 2013 MBI-NIMBioS-CAMBAM Workshops Summer Graduate Workshop 114 Workshop 1: Mathematical Challenges in Neural Network Dynamics 21-30 Workshop 2: Cognitive Neuroscience 31-37 Seminars 115-117 Workshop 3: Disease 38-45 Program Participation 118 Workshop 4: Rhythms and Oscillations 46-51 Future Programs 119-120 Workshop 5: Cellular and Subcellular 52-59 Publications 121-125 Workshop 6: Sensory Systems and Coding 60-71 About MBI Institute Partners IP Mentoring Program MBI Supported IP Meetings Researchers from both the mathematical and biological University of Nottingham sciences (broadly defined) at IP institutions can join the pool MBI Institute Partner conference Multiscale Modelling in of approved scientific mentors of MBI postdoctoral fellows. Medicine and Biology - September 3-5, 2012 Reasonable costs for off-site mentoring are borne by MBI, University of Miami and IP mentors can be similarly funded to visit MBI. Everything Disperses to Miami: The Role of Movement and Dispersal in Ecology, Epidemiology and Environmental Science - December 14-16, 2012 Arizona State University SMB Annual Meeting: 2013 Travel Grant for young researchers - June 10-13, 2013 Current Institute Partners Arizona State University University of California at Irvine Battelle University California at Los Angeles Boston University University of California at San Diego Case Western Reserve University University of Cincinnati Cornell University University of Exeter Drexel University University of Georgia Mission Institute Partners Duke University University of Glasgow To foster innovation in the application of mathematical, Florida State University University of Houston MBI welcomes the participation of other academic statistical, and computational methods in the resolution of Howard University University of Iowa institutions in the MBI Institute Partner Program. This significant problems in the biosciences; IBM University of KwaZulu-Natal program uses MBI matching funds to subsidize the travel expenses of IP member researchers to allow their Indiana University-Purdue University Indianapolis University of Maryland at Baltimore County To foster the development of new areas in the mathematical participation in MBI programs. Instituto Gulbenkian de Ciencia University of Miami sciences motivated by important questions in the Iowa State University University of Michigan biosciences; In addition MBI supports conferences in mathematical Konkuk University University of Minnesota biology held at IP institutions. To engage mathematical and biological scientists in these McGill University Universidad Nacional Autónoma de México pursuits; and Michigan State University University of Notre Dame IP representatives are invited to annual meetings to explore Mississippi State University University of Nottingham - CMMB research and educational opportunities and provide input To expand the community of scholars in mathematical for future institute programs. IP members also receive MBI National Tsing Hua University University of Oxford biosciences through education, training, and support of newsletters, proceedings, and annual reports. New Jersey Institute of Technology University of Pittsburgh students and researchers. The Ohio State University University of Southern California Ohio University University of Twente Penn State University University of Utah Princeton University University of Washington Texas Tech University University of Waterloo Trinity University University of Wyoming Tulane University Vanderbilt University 1 University of California at Davis Virginia Tech 2 About MBI Directors Directors Marty Golubitsky Michael Reed Helen Chamberlin Yuan Lou Director Senior Scientific Advisor Associate Director Associate Director The Director provides the scientific leadership, The Senior Scientific Advisor designs and Works with the director on diversity issues. Responsible for the summer promotes the institution’s mission and goals, implements new programs that promote the graduate program. and is responsible for the overall management mission of the Institute. The Senior Scientific and resource development of the institute. The Advisor will represent the Institute in the director reports to the Board of Trustees. Director’s absence. Tony Nance Grzegorz Rempala Deputy Director Deputy Director Andrej Rotter Laura S. Kubatko Associate Director Associate Director Oversees administration of the postdoctoral Greg Rempala provides scientific advice and Andrej Rotter chairs the MBI Colloquium Laura Kubatko is responsible for MBI education program and informational technology group, support to the