REQUEST FOR APPLICATIONS RFA P-21.2-TCL Tobacco Control and Lung Cancer Screening Please also refer to the Instructions for Applicants document, which will be posted on November 16, 2020 Application Receipt Opening Date: November 16, 2020 Application Receipt Closing Date: February 10, 2021 FY 2021 Fiscal Year Award Period September 1, 2020-August 31, 2021 TABLE OF CONTENTS 1. ABOUT CPRIT ........................................................................................................................ 5 1.1 PREVENTION PROGRAM PRIORITIES .................................................................................... 5 2. FUNDING OPPORTUNITY DESCRIPTION ...................................................................... 6 2.1 SUMMARY ........................................................................................................................... 6 2.2 PROJECT OBJECTIVES .......................................................................................................... 9 2.3 AWARD DESCRIPTION ....................................................................................................... 10 2.4 PRIORITIES ........................................................................................................................ 15 2.5 SPECIFIC AREAS OF EMPHASIS .......................................................................................... 16 2.6 OUTCOME METRICS .......................................................................................................... 16 2.7 ELIGIBILITY ....................................................................................................................... 18 2.8 RESUBMISSION POLICY ..................................................................................................... 19 2.9 EXPANSION POLICY ........................................................................................................... 20 2.10 FUNDING INFORMATION .................................................................................................... 21 2.11 OPPORTUNITY FOR APPLIED RESEARCH ............................................................................ 22 3. KEY DATES ........................................................................................................................... 23 4. APPLICATION SUBMISSION GUIDELINES ................................................................. 23 4.1 INSTRUCTIONS FOR APPLICANTS DOCUMENT ....................................................................... 23 4.2 ONLINE APPLICATION RECEIPT SYSTEM ............................................................................ 23 4.3 SUBMISSION DEADLINE EXTENSION .................................................................................. 24 4.4 APPLICATION COMPONENTS .............................................................................................. 24 4.4.1 Abstract and Significance (5,000 characters) .......................................................................... 24 4.4.2 Goals and Objectives (700 characters each) ........................................................................... 25 4.4.3 Project Timeline (2 pages) ...................................................................................................... 25 4.4.4 Project Plan (12 pages, fewer pages permissible) ................................................................... 25 4.4.5 People Reached (Indirect Contact) .......................................................................................... 28 4.4.6 Number of Services Delivered (Direct Contact)...................................................................... 29 4.4.7 Number of Clinical Services Delivered ................................................................................... 29 4.4.8 Number of Unique People Served (Direct Contact) ............................................................... 29 4.4.9 References ............................................................................................................................... 29 4.4.10 Resubmission Summary ........................................................................................................... 29 4.4.11 Expansion Application Documents .......................................................................................... 30 4.4.12 Most Recently Funded Project Summary, if Applicable (3 pages) ........................................... 30 4.4.13 CPRIT Grants Summary .......................................................................................................... 31 4.4.14 Budget and Justification .......................................................................................................... 31 4.4.15 Current and Pending Support and Sources of Funding ........................................................... 32 4.4.16 Biographical Sketches ............................................................................................................. 32 4.4.17 Collaborating Organizations ................................................................................................... 33 4.4.18 Letters of Commitment (10 pages) ........................................................................................... 33 5. APPLICATION REVIEW .................................................................................................... 33 5.1 REVIEW PROCESS OVERVIEW ............................................................................................ 33 5.2 REVIEW CRITERIA .............................................................................................................. 35 5.2.1 Primary Evaluation Criteria ........................................................................................... 35 5.2.2 Secondary Evaluation Criteria ........................................................................................ 37 CPRIT RFA P-21.2-TCL Tobacco Control and Lung Cancer Screening p.2/47 (Rev 10/16/2020) 6. AWARD ADMINISTRATION ............................................................................................. 38 7. CONTACT INFORMATION ............................................................................................... 39 7.1 HELPDESK ......................................................................................................................... 39 7.2 PROGRAM QUESTIONS ....................................................................................................... 39 8. RESOURCES ......................................................................................................................... 40 9. REFERENCES ....................................................................................................................... 41 APPENDIX A: KEY TERMS ......................................................................................................... 42 APPENDIX B: WRITING GOALS AND OBJECTIVES ............................................................... 45 CPRIT RFA P-21.2-TCL Tobacco Control and Lung Cancer Screening p.3/47 (Rev 10/16/2020) RFA VERSION HISTORY Rev 10/16/2020 RFA release CPRIT RFA P-21.2-TCL Tobacco Control and Lung Cancer Screening p.4/47 (Rev 10/16/2020) 1. ABOUT CPRIT The State of Texas has established the Cancer Prevention and Research Institute of Texas (CPRIT), which may issue up to $6 billion in general obligation bonds to fund grants for cancer research and prevention. CPRIT is charged by the Texas Legislature to do the following: Create and expedite innovation in the area of cancer research and enhance the potential for a medical or scientific breakthrough in the prevention of or cures for cancer; Attract, create, or expand research capabilities of public or private institutions of higher education and other public or private entities that will promote a substantial increase in cancer research and in the creation of high-quality new jobs in the State of Texas; and Develop and implement the Texas Cancer Plan. 1.1. Prevention Program Priorities Legislation from the 83rd Texas Legislature requires that CPRIT’s Oversight Committee establish program priorities on an annual basis. The priorities are intended to provide transparency in how the Oversight Committee directs the orientation of the agency’s funding portfolio. The Prevention Program’s principles and priorities will also guide CPRIT staff and the Prevention Review Council on the development and issuance of program-specific Requests for Applications (RFAs) and the evaluation of applications submitted in response to those RFAs. Established Principles: Fund evidence-based interventions and their dissemination Support the prevention continuum of primary, secondary, and tertiary (includes survivorship) prevention interventions Prevention Program Priorities Prioritize populations disproportionately affected by cancer incidence, mortality, or cancer risk prevalence Prioritize geographic areas of the state disproportionately affected by cancer incidence, mortality, or cancer risk prevalence Prioritize underserved populations CPRIT RFA P-21.2-TCL Tobacco Control and Lung Cancer Screening p.5/47 (Rev 10/16/2020) 2. FUNDING OPPORTUNITY DESCRIPTION 2.1. Summary The ultimate goals of the CPRIT Prevention Program are to reduce overall cancer incidence and mortality and to improve the lives of individuals who have survived or are living with cancer. The ability to reduce cancer death rates depends in part on the application of currently available evidence-based technologies and strategies.