10/7/2015 6:29:47 AM 150111 Therapeutic Effects of Ursodeoxycholic Acid (UDCA) Vs. Endoscopic Retrograde Cholangiography in Biliary sludge and Microlithiasis ﻣﺠﺎﺭﯼ ﺻﻔﺮﺍﻭﯼ Category : 8 Introduction : Biliary microlithiasis and sludge has been considered as a main cause of cute biliary pain and pancreatitis. The standard therapeutic approaches are medical and interventional .There is not enough data regarding usage and chose one of them .To determine the therapeutic values of ursodeoxycholic acid Vs. endoscopic retrograde cholangiography Methods : Between 2013 to 2015, patients who were referred to gastrointestinal clinic for follow-up of biliary sludge and microlithiasis enrolled to this study. The exclusion criteria were presence of CBD stone, CBD dilatation, history of papillotomy, any related complications and need of intervention. All of them underwent physical exam, abdominal ultrasonography and endoscopic. They randomly divided in two groups; medical and ERCP. Patients follow-up for six months .The clinical manifestations as well as lab data was compared in the end of study. Results : A total 116 patients was enrolled in this study .24 patients excluded for complications or needs intervention also 8 patients refused to continue. 7 and 5 patients of UDCA and ERCP groups respectively underwent cholecystectomy during our follow-up. Pancreatitis was seen in 5 patients; 4 and 1 in UDCA and ERCP group .the clinical manifestation as well as lab data were improve in both group but this improvement was significant in ERCP group. Conclusion : Usage of UDCA improves all symptoms as well as lab test .It could be ordered in weak patients or who is in waiting list of ERCP or Surgery. FirstName LastName Institute University IsPresenter Firoozgar Farhad Zamani Gastrointestinal Hospital, Iran & Liver Disease University of Research Medical Center Sciences (GILDRC), Tehran, Iran. Firoozgar Mitra Ameli Gastrointestinal Hospital, Iran & Liver Disease University of Research Medical Center Sciences (GILDRC), Tehran, Iran. FirstName LastName Institute University IsPresenter Firoozgar Masoudreza Sohrabi Gastrointestinal Hospital, Iran & Liver Disease University of Research Medical Center Sciences (GILDRC), Tehran, Iran. Firoozgar Hossein Ajdarkosh Gastrointestinal Hospital, Iran & Liver Disease University of Research Medical Center Sciences (GILDRC), Tehran, Iran. Firoozgar Gholamreza Hemmasi Gastrointestinal Hospital, Iran & Liver Disease University of Research Medical Center Sciences (GILDRC), Tehran, Iran. Firoozgar Mohammad Hosseini Azar Gastrointestinal Hospital, Iran & Liver Disease University of Research Medical Center Sciences (GILDRC), Tehran, Iran. Firoozgar Mahmoodreza Khoonsari Gastrointestinal Hospital, Iran & Liver Disease University of Research Medical Center Sciences (GILDRC), Tehran, Iran. Firoozgar Mehdi Nikkhah Gastrointestinal Hospital, Iran & Liver Disease University of Research Medical Center Sciences (GILDRC), Tehran, Iran..