CURRENT Investigator Brochure List Date Posted Size 003801 - Methoxyamine hydrochloride (TRC102) - 10-14 - Ver3..pdf 10/09/2014 1,021 KB 048006 - 5-Fluoro-2’-deoxycytidine (FdCyd) - 01-14.pdf 01/09/2014 537 KB 102816 - Azacitidine - 08-15 Ver 12.pdf 10/01/2015 3 MB 102816 - Azacitidine - Summary of Changes - 08-15 Ver 12.pdf 10/01/2015 140 KB 127716 - Decitabine (5-aza-2'-deoxycytidine) - 04-12 - Ver6.pdf 09/24/2012 1 MB 281612 - DMS612 (Dimethane Sulfonate) - 04-14.pdf 04/24/2014 175 KB 301463 - Poly ICLC Hiltonol - 05-14 - Ver9.pdf 08/26/2014 412 KB 630176 - Romidepsin (Depsipeptide; FK228) - 04-15 - Ver 14.pdf 04/16/2015 939 KB 630176 - Romidepsin (Depsipeptide; FK228) - Summary of Changes - 04-15 - Ver 14.pdf 04/16/2015 93 KB 639966 - Perifosine - 03-14 - Ver 14.pdf 04/14/2014 4 MB 663249 - Triapine (injection and capsule) - 09-15.pdf 10/08/2015 1 MB 663249 - Triapine (injection and capsule) - Summary of Changes - 09-15.pdf 10/08/2015 125 KB 66847 - Thalidomide (Thalomid) - 12-15 - Ver14.pdf 03/17/2016 1 MB 66847 - Thalidomide (Thalomid) Summary of changes - 12-15 - Ver14.pdf 03/17/2016 165 KB 672423 - InterLEUKIN-12 - 12-14.pdf 02/09/2015 1 MB 676422 - Immunotoxin LMB-2 (Anti-Tac(Fv)-PE-38) - 05-15.pdf 06/02/2015 466 KB 681239 - Bortezomib - 06-15 - Ver18.pdf 08/11/2015 1 MB 681239 - Bortezomib - Summary Of Changes - 06-15 - Ver18.pdf 08/11/2015 153 KB Prepared by CTEP 4/1/2016 Page 1 of 8 CURRENT Investigator Brochure List Date Posted Size 683864 - Temsirolimus (PF-05208748) - 12-15.pdf 01/28/2016 909 KB 683864 - Temsirolimus (PF-05208748) - Summary of Changes - 12-15.pdf 01/28/2016 3 MB 686673 - Nelarabine (506U78) - 11-05 - Ver7.pdf 11/19/2014 1 MB 688097 - RO0452317 Herceptin (Trastuzumab) - 10-15 - Ver16.pdf 11/02/2015 2 MB 696599 - FLT3 Ligand CDX-301 - 11-15 Ver 3.pdf 11/30/2015 992 KB 701852 - Vorinostat (SAHA, Zolinza) - 08 -13 - Ver 8.pdf 08/05/2013 8 MB 702818 - R115777 (tipifarnib, Zarnestra) - 05-08 - Ver11.pdf 05/14/2009 2 MB 702818 - R115777 (tipifarnib, Zarnestra) - Summary of Changes - 05-08 - Ver11.pdf 05/14/2009 35 KB 703813-Revlimid (Lenalidomide)- 02-15 -Ver 18.pdf 03/30/2015 1 MB 703813-Revlimid (Lenalidomide)- Summary of Changes - 02-15- Ver 18.pdf 03/30/2015 173 KB 704865 - Bevacizumab(Avastin) - 11-15 - Ver.23.pdf 12/09/2015 1 MB 706995 - MS-275 (SNDX-275, Entinostat) - 11-15 Ver14.0.pdf 12/17/2015 1 MB 706995 - MS-275 (SNDX-275, Entinostat) - Summary of Changes - 11-15 Ver14.0.pdf 12/17/2015 53 KB 707389 -E7389(ERIBULIN)- Summary of Changes 08-14-Ver 12.pdf 01/26/2015 114 KB 707389 -E7389(ERIBULIN)-07-14-Ver 12.pdf 01/26/2015 1 MB 707389 -E7389(ERIBULIN)-Addendum -08-14-Ver 12.pdf 01/26/2015 80 KB 710428 - BMS 247550 (ixabepilone, Ixempra) - 06-09 - ver10.pdf 06/30/2009 1,010 KB 710658; 708039 - rF-TRICOM; rV-TRICOM - 08-10.pdf 10/05/2010 200 KB Prepared by CTEP 4/1/2016 Page 2 of 8 CURRENT Investigator Brochure List Date Posted Size 717170; 717171 - PROSTVAC-VF - 12-14 - Ver3.pdf 06/16/2015 1 MB 718781 - OSI-774 - Erlotinib (Tarceva) ASP5901 - 02-15 - Ver19.pdf 08/20/2015 1 MB 718781 - Summary Of Changes OSI-774 - Erlotinib (Tarceva) ASP5901 - 02-15 - Ver19.pdf 09/11/2015 94 KB 724770 - Ziv-aflibercept, VEGF-Trap, AVE0005 -12-15-Ver 14.pdf 02/17/2016 2 MB 724770 - Ziv-aflibercept, VEGF-Trap, AVE0005- Summary Of Changes -12-15-Ver 14.pdf 02/17/2016 171 KB 724772 - BAY 43-9006 (SORAFENIB) - 08-15-Ver16.0.pdf 01/28/2016 1 MB 726188 -5-iodo-2-pyrimidinone - deoxyribose-IPdR - 01-15.pdf 01/26/2015 457 KB 726388 - CAT-5001 (SS1(dsFv) PE38) - 7-13.pdf 07/16/2013 491 KB 726630 - PXD-101(Belinostat) - 04-15 - Ver 12.pdf 07/29/2015 2 MB 727027; 727026 - PANVAC-VF - 12-13.pdf 12/27/2013 259 KB 727989 - GW572016 (Lapatinib) - 01-16 - Ver 17.pdf 03/31/2016 1 MB 727989 - GW572016 (Lapatinib) - Summary of Changes - 01-16 - Ver 17.pdf 03/31/2016 53 KB 729968 -Reolysin - 02-16 - Ver15..pdf 03/31/2016 1 MB 732208 - AZD2171 (Cediranib, Recentin) Appendix A - 09-15 - Ver17.pdf 09/24/2015 174 KB 732208 - AZD2171 (Cediranib, Recentin)-09-15 - Ver17.pdf 09/24/2015 892 KB 732442 -Ipilimumab-(MDX-010; Transfectoma-derived) - 03-16 - Ver 19.pdf 03/31/2016 11 MB 732517 - BMS-354825 (DASATINIB) - 06-15 - Ver 15.pdf 08/07/2015 10 MB 732517 - BMS-354825 (DASATINIB) Summary of Changes - 06- 15 - Ver 15.pdf 08/07/2015 1 MB Prepared by CTEP 4/1/2016 Page 3 of 8 CURRENT Investigator Brochure List Date Posted Size 733504 - Everolimus (Afinitor RAD001) - 05-15 - Ver 14.pdf 11/02/2015 822 KB 733504 - Everolimus (Afinitor RAD001) Erratum - 05-15 - Ver 14.pdf 11/02/2015 753 KB 733504 - Everolimus (Afinitor RAD001) Summary of Changes - 05-15 - Ver 14.pdf 11/02/2015 143 KB 736511 - Sunitinib Malate - Investigator's Brochure - 06-15.pdf 01/07/2016 2 MB 736511 - Sunitinib Malate - Summary Of Changes - 06-15.pdf 01/07/2016 3 MB 737664 - Veliparib (ABT-888) - 06-15 - Ver9.pdf 12/17/2015 6 MB 737754 - GW786034-(Pazopanib) - 12-14 - Ver12.PDF 02/20/2015 2 MB 737754 - GW786034-(Pazopanib) -Memo- 12-14 - Ver12 - Redistribution memo.pdf 02/20/2015 158 KB 737754 - GW786034-(Pazopanib) -Memo- 12-14 - Ver12.pdf 02/20/2015 189 KB 740102 - Pertuzumab - 02-15- ver14.pdf 03/18/2015 1 MB 742460 - IMC-A12 (Cixutumumab) - 09-13-.pdf 11/20/2013 4 MB 745101 - Recombinant Human IL-15 - 06-15.pdf 07/01/2015 3 MB 747135 - SCH 727965 (Dinaciclib, MK-7965) - 10-14 - Ver.11.pdf 10/07/2014 6 MB 747691-Vismodegib (GDC- 0449) -01-16-Ver 10.pdf 02/05/2016 2 MB 747856 - Olaparib(AZD2281) -06-15-Ver12.pdf 10/08/2015 2 MB 747888 - MLN8237 - 07-15 - Ver10.pdf 11/02/2015 2 MB 748645 -PCI-32765 (Ibrutinib) - 06-15 - Ver9.pdf 07/13/2015 710 KB 748645 -PCI-32765 (Ibrutinib) - Summary Of Changes - 06-15 - Ver9.PDF 07/13/2015 102 KB Prepared by CTEP 4/1/2016 Page 4 of 8 CURRENT Investigator Brochure List Date Posted Size 748645 -PCI-32765 (Ibrutinib) - Addendum 1 06-15 - Ver9.pdf 01/07/2016 64 KB 748645 -PCI-32765 (Ibrutinib) - Addendum 2 06-15 - Ver9.pdf 01/07/2016 79 KB 748726 - BMS936558 (Nivolumab) - 06-15 - Ver14.pdf 07/14/2015 4 MB 748726 - BMS936558 (Nivolumab) Erratum 01 - 06-15 - Ver14.pdf 01/21/2016 2 MB 748727; 741078 - AZD6244 (Capsules and Powder&Oral Suspension) - 01-16 - Ver 16.pdf 01/28/2016 6 MB 749005 - Crizotinib (PF-02341066) - 10-15.pdf 01/07/2016 927 KB 749005 - Crizotinib (PF-02341066) -Summary of Changes - 10- 15.pdf 01/07/2016 1 MB 749225 - RO4929097 - 06-10 - ver4.pdf 07/13/2010 2 MB 749607-MK-2206-02-14-Ver7.pdf 09/22/2014 2 MB 749710 - SGN-35 - 10-15 - Ver 13.pdf 11/02/2015 1 MB 749712 - AT13387 - 03-15 - Ver 10.pdf 03/30/2015 3 MB 750008 - AMG 479 (Ganitumab) - 11-13 - Ver 9.pdf 05/23/2014 665 KB 750008 - AMG 479 (Ganitumab)-Summary of Changes - 11-13 - Ver 9.pdf 05/23/2014 131 KB 750238 - ABT-263 - (Navitoclax) 12-15 - Ver 12.pdf 01/05/2016 2 MB 750393 - Z-Endoxifen HCL - 01-15.pdf 02/18/2015 668 KB 750691 - Afatinib - 07 -15 -Ver16.pdf 09/21/2015 2 MB 750832 - ARQ 197 - 11-13 - Ver9.0.pdf 11/25/2013 2 MB 750832 - ARQ 197 - SOC - 11-13 - Ver9.0.pdf 11/25/2013 170 KB Prepared by CTEP 4/1/2016 Page 5 of 8 CURRENT Investigator Brochure List Date Posted Size 751082 - Linsitinib (ASP7487, OSI-906) - 03-15 - Ver 5..pdf 05/14/2015 3 MB 751084 -AZD1775 - 02-15 - Ver12.pdf 03/19/2015 1 MB 751173 - Trebananib (AMG 386) - 12-15 Ver 11.pdf 01/20/2016 1 MB 751173 - Trebananib (AMG 386) Summary of Changes- 12-15 Ver 11.pdf 01/20/2016 71 KB 754227 - TRC105-01-16-Ver9.0.pdf 02/17/2016 2 MB 756502 - (birinapant)TL32711 , 04-15, Ver7.pdf 11/19/2015 2 MB 761968 - Cabozantinib(XL184) - 07-15 - Ver 11-Summary of Changes.pdf 07/28/2015 408 KB 761968 -Cabozantinib(XL184) - 07-15 - Vers 11.pdf 07/28/2015 1 MB 763093 - GSK1120212-Trametinib - 01-16 - Ver7.pdf 02/17/2016 1 MB 763093 - GSK1120212-Trametinib - Summary Of Changes - 01-16 - Ver7.pdf 02/17/2016 140 KB 763737 - Glembatumumab Vedotin-CDX-011 -08-15 -ver6.pdf 09/28/2015 3 MB 763760 - GSK2118436 (Dabrafenib) -10-15 -Ver7.pdf 11/09/2015 2 MB 763760 - GSK2118436 (Dabrafenib) Mono and in Combination with Trametinib Release Memo_IB V7_14....pdf 11/09/2015 326 KB 764038 – Chimeric Monoclonal Antibody - Summary of Changes14.18 – 09-15.PDF 10/22/2015 1 MB 764038 – Chimeric Monoclonal Antibody 14.18 – 09-15.PDF 10/22/2015 5 MB 765986 - Blinatumomab (AMG 103) - 04-15 - Ver 16.1.pdf 01/20/2016 1 MB 765986 - Blinatumomab (AMG 103) Summary of Changes - 04- 15 - Ver 16.1.pdf 01/20/2016 174 KB 766086 - INCB024360 - 12-15 - Ver7.pdf 01/28/2016 1 MB Prepared by CTEP 4/1/2016 Page 6 of 8 CURRENT Investigator Brochure List Date Posted Size 767034 - GSK2141795 - 09-14 - Ver7.PDF 10/15/2014 746 KB 767034 - GSK2141795 - SOC - 09-14 - Ver7.pdf 03/02/2015 769 KB 767909 - Pomalidomide (CC-4047) - 05-15 - Ver 21.pdf 07/02/2015 2 MB 767909 - Pomalidomide (CC-4047) - Summary of Changes - 05- 15 - Ver 21.pdf 07/02/2015 133 KB 768435 - MLN0128 - 03-15 - Ver 8.pdf 04/10/2015 834 KB 771561 - Talazoparib (BMN 673) - 04-15 - Ver6.pdf 05/14/2015 423 KB 772256 – Palbociclib (PD-0332991) 12-15.pdf 01/07/2016 1 MB 772256 – Palbociclib (PD-0332991) Summary of Changes - 12- 15.pdf 01/07/2016 3 MB 772468 - CDX-1401 - 10-13 - Ver3.pdf 11/12/2013 2 MB 776864 - MK-3475 - 08-15 - Ver10.pdf 09/11/2015 2 MB 777169 - Ganetespib - 11-15 - Ver 11.pdf 12/01/2015 2 MB 778372 - (Varlilumab) CDX-1127 - 07-14 - Ver 4.0.pdf 01/20/2016 2 MB 778709 - MEDI4736 - 09-15 - Ver 8.pdf 10/01/2015 3 MB 778795 - GDC-0032 (RO5537381 Taselisib) - 12-15 - Ver 6.pdf 12/18/2015 759 KB 780162 - VX-970 - 05-15 - Ver5.0.pdf 08/28/2015 2 MB 780263 - Ado-Trastuzumab Emtansine - 12-14 - Ver.