US 20100310518A1 (19) United States (12) Patent Application Publication (10) Pub. No.: US 2010/0310518 A1 Hungenberg et al. (43) Pub. Date: Dec. 9, 2010 (54) COMBINATIONS OF FLUBENDIAMIDE AND (30) Foreign Application Priority Data BENEFICIAL SPECIES Jun. 3, 2009 (DE) ......................... 102OO9026699.2 (75) Inventors: Heike Hungenberg, Langenfeld Publication Classification (DE): Hans-Jürgen Schnorbach, (51) Int. Cl Monheim (DE); Wolfram AoiN3/00 (2006.01) Andersch, Bergisch Gladbach AOIN 63/04 (2006.01) (DE); Udo Reckmann, Koln (DE) AOIN 65/00 (2009.01) AOIP 7/04 (2006.01) Correspondence Address: AOIP 7/02 (2006.01) SERNE, KESSLER, GOLDSTEIN & FOX P.L. (S2) usc. 424/93.3; 424/93.5; 424/93.4: 1100 NEW YORKAVENUE, N.W. 424/93.6; 424/538; 424/520 WASHINGTON, DC 20005 (US) (57) ABSTRACT The novel combinations of flubendiamide and beneficial spe (73) Assignee: Bayer CropScience AG, Monheim cies comprising flubendiamide and at least one beneficial (DE) species from the orders or Suborders of the Araneae, Acari, Dermaptera, Hymenoptera, Coleoptera, Neuroptera, Thysan (21) Appl. No.: 12/793,078 optera, Heteroptera, Diptera, Hemiptera, Dermaptera and/or Parasitiformes or at least one bacteria strain or at least one (22) Filed: Jun. 3, 2010 virus strain for the effective control of unwanted pests. US 2010/0310518 A1 Dec. 9, 2010 COMBINATIONS OF FLUBENDAMIDE AND insects and arachnids from the orders or suborders of the BENEFICIAL SPECIES Araneae, Acari, Dermaptera, Hymenoptera, Coleoptera, Neuroptera, Thysanoptera, Heteroptera, Diptera, Hemiptera, Dermaptera and/or Parasitiformes, Plannipennia, particularly 0001. The present invention relates to combinations of preferably from the families of the Vespidae, Aphelinidae, flubendiamide and beneficial species comprising 3-iodo-N'- Trichogrammatidae, Encyrtidae, Mymaridae, Eulophidae, (2-mesyl-1,1-dimethylethyl)-N-(4-1.2.2.2-tetrafluoro-1- Alloxystidae, Megaspilidae, Braconidae, Cantharidae, Coc (trifluoromethyl)ethyl-o-tolyl-phthalamide, known as cinellidae, Cleridae, Chrysopidae, Hemerobiidae, Anthoc flubendiamide, and at least one type of beneficial species for oridae, Miridae, Forficulidae, Phytoseiidae, Carabidae, Sta the effective and environmentally friendly control of animal phylenidae. Ichneumonidae, Bracconidae, Aphidiidae, pests such as insects and/or unwanted acarids. Eumenidae, Sphecidae, Tachnidae, Syrphidae, Cecidomyi 0002. The insecticidal and acaricidal action of 3-iodo-N'- idae, Stigmaeidae, Angstidae, Trombidiidae, Nabidae, Pen (2-mesyl-1,1-dimethylethyl)-N-(4-1.2.2.2-tetrafluoro-1- tatomidae, Reduviidae, Coniopterygidae, Chameiidae, Asil (trifluoromethyl)ethyl-o-tolyl-phthalamide (flubendiamide) idae and Euzetidae (soil mites). Furthermore predatory mites and also its Suitability as pest control agent have been known and nematodes. for a longtime and were described for the first time in EP-A-1 0008 Preference is given to combinations of flubendia 006 107. It is also known that the activity of flubendiamide mide and beneficial species comprising flubendiamide and at can be increased by combining it with other chemicals such least one beneficial species selected from the insects and as, for example, insecticides. Thus, for example, EP-A-1 380 arachnids from groups (1) to (7): 209 and WO 2004/034786 describe the enhanced activity of (1) predatory mites from the order Amblyseius spp., Such as, combinations comprising flubendiamide and other insecti for example, Amblyseius barkeri and Ambly seius cucumeris, cides. An increased insecticidal and acaricidal activity of and also from the order Hypoaspis spp., Such as, for example, flubendiamide by addition of ammonium or phosphonium Hypoaspis miles, Hypoaspis aculeifer and from the order salts has also been described (WO 2007/068357). Phytoseiulus spp., Such as, for example, Phytoseiulus persi 0003. The use of beneficial species for controlling pests is milis, generally known (for example from “Knowing and recogniz (2) nematodes from the order Steinernema spp., Such as, for ing'; M. H. Malais, W. J. Ravensberg, published by Koppert example, Steinernema feltiae and Steinernema carpocapsae, B.V., Reed Business Information (2003)). Beneficial species and from the order Heterorhabditis spp., such as, for are in most cases arachnids or insects which are in some way example, Heterorhabditis bacteriophora, or other useful for man, in particular by relying on other (3) bugs (Heteroptera) from the orders Anthocoris spp. insects, for their part referred to as pests, as food or as a host. (flower bugs). Such as, for example, Anthocoris memorum, However, the term “beneficial species” is not limited to arach Orius spp. Such as, for example, Orius majusculus, and Mac nids and insects. In the present invention, it also includes rolophus spp. (predatory bugs), Such as, for example, Mac fungi or bacteria or virus strains Suitable for controlling pests. rolophus caliginosus and Macrolophus pygmaeus, Beneficial species are particularly suitable for controlling (4) lacewings (Plannipennia) from the orders Chrysoperla pests in greenhouses. The use of beneficial species has the spp. Such as, for example, Chrysoperla carnea (common advantage that no resistencies are developed and that there are green lacewing) and Chrysopa perla (golden-eyes), and no waiting times for cultivation and care measures and for Hemerobius spp. Such as, for example, Hemerobius humuli harvesting. Moreover, by employing beneficial species, the nus (aphid lions); user is not exposed to crop protection agents. (5) hymenopterans (Hymenoptera) from the orders Tri 0004 For pest control, a sufficient quantity of beneficial chogramma spp., Aphidius spp. (ichneumon wasps), such as, species is released or inoculated at the site of action (for for example, Aphidius Colemani, A. Aphidius ervi., Lariopha example in a greenhouse). In general, the beneficial species gus spp. (pteromalid wasp). Such as, for example, Lariopha are only employed in case of an attack by pests (curative). gus distinguendus, Lysiphlebus spp., Such as, for example, Since beneficial species are the natural enemies of the pests to Lysiphlebus testaceipes, Encarsia spp. (ichneumon wasp), be controlled, their activity spectrum is frequently limited to Such as, for example, Encarsia formosa, Dacnusa spp., Such the specific pest and in some cases even to specific develop as, for example, Dacnusa Sibirica, Aphelinus spp., Such as, ment stages of these pests. However, since a plurality of pest for example, Aphelinus abdominalis, Diglyphus spp., Such as, species having different control requirements, such as, for for example, Diglyphus isaea, Leptomastix spp., Such as, for example, time of application, beneficial species and benefi example, Leptomastix abnormis, Dabnusa spp., Such as, for cial species climate, may occur in a crop, the crop has to be example, Dabnusa Sibirica, Trichogramma spp. (ichneumon monitored regularly and requires a rapid reaction in the case wasp). Such as, for example, Trichogramma brassicae, Tri of an attack. Moreover, the user has to have in-depth knowl chogramma dendrolini and Trichogramma evanescens. edge of the crop, the pests and the beneficial species. pteromalid wasp Lariophagus distinguendus, 0005. If the attack by pests is noticed too late and as a result the pest population has grown too much, beneficial (6) beetles (Coleoptera) from the orders Coccinella spp., such species alone are not sufficient to control the pests, and a as, for example, Coccinella Septempunctata and Cryptolae combined use of the beneficial species with chemical pesti mus spp., Such as, for example, Cryptolaemus montrouzieri; cides is required. (7) Diptera from the orders Episyrphus spp., Such as, for 0006. It has now been found that a combination of fluben example, Episyrphus balteatus, Feltiella spp., Such as, for diamide and beneficial species avoids the disadvantages men example, Feltiella acarisuga, and Aphidoletes spp., Such as, tioned above and is additionally highly effective. for example, Aphidoletes aphidimyza (predatory gall midge); 0007. The beneficial species that can be used in the com or selected from the following microorganisms: Bacillus thu bination according to the invention are microorganisms such ringiensis, Bacillus firmus, Bacillus subtilis, Baculoviruses, as fungi (for example Metarhizium anisopliae or Beauveria Beauveria brongniartii and Beauveria bassiana, Metarhi bassiana) or bacteria or virus strains (for example Bacillus Zium anisopliae, Metarhizium acridum and Thanasinus for strains or baculoviruses such as granulosis viruses) and also inicarius. US 2010/0310518 A1 Dec. 9, 2010 0009 Preference is given to combinations of flubendia eficial species are also present when the beneficial species is mide and beneficial species comprising flubendiamide and at present on the plant even before the treatment, and the treat least one beneficial species selected from the beneficial spe ment with flubendiamide shifts the balance between pest and cies mentioned in Table 1. beneficial species in favour of the beneficial species. 0010 For the purpose of the present invention, combina 0011. Accordingly, the invention also relates to the use of tions of flubendiamide and beneficial species also include flubendiamide in combination with beneficial species, pref those combinations where flubendiamide and the beneficial erably a beneficial species selected from one of groups (1) to species are applied at different times and/or locations. Thus, (7), for controlling animal pests. Preferably, flubendiamide