ASBMR 2013 Annual Meeting Baltimore Convention Center October 4-7, 2013 TABLE OF CONTENTS ASBMR Council/Staff ......................................................................................... iv Program Committee ............................................................................................ iv Abstract Reviewers .............................................................................................. v ASBMR Committee Members/Representatives ............................................................ vii Award Winners .................................................................................................. x Supporters ....................................................................................................... xii General Information .......................................................................................... xiii ASBMR Policies ............................................................................................... xiv Continuing Medical Education Credit ..................................................................... xvi Meeting Resource Materials ................................................................................ xvii Travel Resources ............................................................................................. xviii ASBMR Networking Center ................................................................................. xix Information for Speaker and Poster Presenters ........................................................... xx FRIDAY, OCTOBER 4, 2013 Day-at-a-Glance ............................................................................................ 1 ASBMR Registration Open ............................................................................... 3 Morning Networking ...................................................................................... 3 Gerald D. Aurbach Lecture - Wnt Signaling and Stem Cell Control ............................. 3 Networking Break .......................................................................................... 3 Meet-the-Professor Sessions ............................................................................... 3 Meeting Overview for Health Professionals ............................................................ 4 Grant Writing Workshop - Mock Study Section: Insights into Grant Reviewing Processes ... 5 Distinguished Orals - Lifestyle ........................................................................... 5 Distinguished Orals - Basic Science Approaching Clinical Application ........................... 6 Networking Break .......................................................................................... 7 Symposium - Greg Mundy Memorial Session: Malignancy and Bone ............................ 8 Symposium - Sarcopenia/Osteopenia: One Affliction? ............................................... 8 Networking Break .......................................................................................... 9 Symposium - FGF2013 ..................................................................................... 9 Symposium - Personalized Medicine: Application to Bone Diseases ............................... 9 Networking Break ......................................................................................... 10 Symposium - What’s Hot in Inflammatory Bone Disease .......................................... 10 ASBMR/ECTS Clinical Debate - Treatments Developed for Fracture Prevention in Osteoporosis Can Be Used in Patients with Chronic Kidney Disease ......................... 10 Oral Poster Presentations: Clinical ..................................................................... 11 Oral Poster Presentations: Basic ........................................................................ 12 Discovery Hall Opening .................................................................................. 14 Young Investigator/First-Time Attendee/Minority Investigator Reception ...................... 14 Welcome Reception & Plenary Poster Session ........................................................ 14 The ASBMR 2013 Brightest Boneheads Quiz Show ................................................. 31 Young Investigator and Minority Investigator Networking Hour ................................ 31 Nutrition Working Group ............................................................................... 31 Rare Bone Disease Working Group .................................................................... 31 Bone Turnover Markers Working Group ............................................................. 32 Working Group on Skeletal Aging ..................................................................... 33 Muscle and Bone Working Group ...................................................................... 33 ASBMR Speed Networking Event ...................................................................... 34 i SATURDAY, OCTOBER 5, 2013 Day-at-a-Glance ........................................................................................... 35 ASBMR Networking Breakfast ......................................................................... 37 ASBMR Registration Open .............................................................................. 37 Morning Networking ..................................................................................... 37 Posters Open ............................................................................................... 37 Distinguished Orals - Dynamics of the Musculoskeletal System .................................. 37 John H. Carstens Memorial Distinguished Orals - Osteoporosis Treatment .................... 39 Discovery Hall Open ...................................................................................... 40 Discovery Hall Networking Break ...................................................................... 40 Success in Research: Leadership Lessons from 2013 ASBMR Esteemed Awardees ............ 41 Oral Poster Presentations: Basic ........................................................................ 41 Oral Poster Presentations: Clinical ..................................................................... 43 Meet-the-Professor Sessions .............................................................................. 45 Poster Session I & Poster Tours ........................................................................ 46 Late-Breaking Posters I ................................................................................. 108 Clinical Roundtable/Case Conference - Interpretation of Clinical Laboratory Testing ...... 112 Louis V. Avioli Lecture - Epigenetic Regulation of Skeletal Biology and Pathology ........ 112 Concurrent Orals - Bone Active Drugs: Clinical ................................................... 113 Concurrent Orals - Bone Active Drugs: Translational ............................................ 113 Concurrent Orals - Bone Disorders .................................................................. 114 Concurrent Orals - Mechanical Loading Mechanisms ............................................ 115 Discovery Hall Networking Break .................................................................... 115 State-of-the-Art Lectures - Osteocytes Take Center Stage ........................................ 115 Symposium - Hidden Regulators of Skeletal Metabolism: Energy, Fat, Fluid ................ 116 Clinical Evening at ASBMR - Do Our Treatments for Osteoporosis Harm Our Patients? . 117 Basic Distinguished Orals & Networking Reception - Multi-Organ Interactions with the Musculoskeletal System ............................................................................. 117 ASBMR Bone Bash Networking Event .............................................................. 119 SUNDAY, OCTOBER 6, 2013 Day-at-a-Glance ......................................................................................... 120 Morning Networking ................................................................................... 122 ASBMR Registration Open ............................................................................ 122 Distinguished Orals - New Perspectives in Metabolic Bone Disease ............................ 122 Distinguished Orals - Powerful Signaling Pathways ............................................... 124 Posters Open ............................................................................................. 125 Discovery Hall Open .................................................................................... 125 Discovery Hall Networking Break .................................................................... 125 Funding Opportunities in a Changing NIH Landscape ........................................... 125 Oral Poster Presentations: Clinical ................................................................... 125 Oral Poster Presentations: Basic ...................................................................... 127 Meet-the-Professor Sessions ............................................................................ 129 Poster Session II & Poster Tours ..................................................................... 130 Late-Breaking Posters II ............................................................................... 190 Clinical Roundtable/Case Conference - Treating Osteoporosis Associated with Chronic Kidney Disease ....................................................................................... 194 JBMR Publications Workshop .......................................................................