JULIA A. KALOW Department of Chemistry Northwestern University work: (847) 467-4972 2145 Sheridan Road [email protected] Evanston, IL 60208-3113 http://sites.northwestern.edu/kalowlab/ PROFESSIONAL EXPERIENCE Assistant Professor of Chemistry, Northwestern University 2016–present • Research interests: polymer chemistry, synthetic methodology, photochemistry, catalysis, physical organic chemistry, tissue engineering, sustainable polymers, organic materials Ruth L. Kirschstein Postdoctoral Fellow, Massachusetts Institute of Technology 2013–2016 Advisor: Professor Timothy M. Swager • Developed an efficient synthesis of telechelic P3HT and a versatile strategy to prepare miktoarm branched polymers based on ring-opening metathesis polymerization. • Studied the self-assembly of novel architectures of conjugated polymers in solution and in bulk. • Designed responsive emulsions and developed strategies for the use of tunable complex emulsions in enzyme sensing. Graduate Research Assistant, Princeton University, Department of Chemistry 2008–2013 Advisor: Professor Abigail G. Doyle Thesis title: Catalytic strategies for asymmetric nucleophilic fluorination using a latent HF source: Development and mechanistic investigations • Initiated a program in asymmetric catalytic nucleophilic fluorination in the Doyle lab and introduced the use of benzoyl fluoride as a latent HF source for C–F bond formation. • Discovered key mechanistic insights into cooperative catalysis in the fluorination reactions that have led to additional projects, including selective radiofluorination. Intern, Merck Research Laboratories, Medicinal Chemistry, Boston, MA Summer 2007 • Investigated metal-catalyzed trifluoromethylation methods (with Dr. Jed Hubbs). Undergraduate Researcher, Columbia University, Department of Chemistry 2005–2008 Advisor: Professor James L. Leighton • Participated in studies toward the synthesis of isocyclocitrinol A (with Dr. Arash Soheili). • Developed an enantioselective imino-Nazarov rearrangement (with Dr. Gregory Notte). EDUCATION Princeton University, Princeton, NJ 2008–2013 Ph.D., Chemistry Columbia University, New York, NY 2004–2008 B.A. with honors, Chemistry and Creative Writing, summa cum laude AWARDS AND HONORS Marion Milligan Mason Award for Women in the Chemical Sciences, AAAS 2021 Julia Kalow: curriculum vitae 2 Organic Reactions Lecturer, Hope College 2019 RCSA Scialog Fellow: Chemical Machinery of the Cell 2019 Arthur K. Doolittle Award, PMSE 2019 NSF CAREER Award 2019 PMSE Young Investigator 2019 Searle Fellows Program, Searle Center for Advancing Learning and Teaching 2017-2018 3M Non-Tenured Faculty Award 2018 Thieme Chemistry Journal Award 2018 Young Investigator Award, Air Force Office of Scientific Research 2017 Rising Stars in Chemistry Symposium, invitee, University of Chicago 2015 Ruth L. Kirschstein NIH NRSA Postdoctoral Fellowship 2013–2016 Charlotte Elizabeth Procter Honorific Fellowship, Princeton University 2012–2013 ACS Division of Organic Chemistry Graduate Fellowship, sponsored by Pfizer 2011–2012 Third-Year Seminar Award, Department of Chemistry, Princeton University 2011 Bristol-Myers Squibb Endowed Fellowship in Synthetic Organic Chemistry 2010 National Science Foundation Pre-Doctoral Fellowship 2008–2011 Hugh Scott Taylor Award, Princeton University 2008–2012 Salutatorian, Columbia College 2008 Karen Osney Brownstein Prize for Creative Writing, Columbia College 2008 Phi Beta Kappa, Columbia College 2007 Barry M. Goldwater Scholarship, Honorable Mention 2007 Pfizer Summer Undergraduate Research Fellowship 2006 PUBLICATIONS (undergraduate co-authors are underlined) https://www.ncbi.nlm.nih.gov/myncbi/1Dqqd43Cbpcwzj/bibliography/public/ Independent career 13. Ishibashi, J. S. A.; Pierce, I. C.; Chang, A. B.; Zografos, A.; Fang, Y.; Weigand, S. J.; Bates, F. S. Kalow, J. A.* “Mechanical and structural consequences of associative dynamic cross-linking in acrylic diblock copolymers.” Macromolecules, in revision. [ChemRXiv, DOI:10.26434/chemrxiv.10000232] 12. Lin, T.-S.; Rebello, N.; Beech, H. K.; Wang, Z.; El-Zaatari, B.; Lundberg, D.; Johnson, J. A.; Kalow, J. A.; Craig, S. L.; Olsen, B. D.* “PolyDAT: a generic data schema for polymer characterization.” J. Chem. Inf. Model., accepted. [DOI: 10.1021/acs.jcim.1c00028] • Selected for ACS Editor’s Choice. 11. Padgaonkar, S.;† Eckdahl, C. T.;† Sowa, J. K.; López-Arteaga, R.; Westmoreland, D. E.; Woods, E. F.; Irgen- Gioro, S.; Nagasing, B.; Seideman, T.; Hersam, M. C.; Kalow, J. A.;* Weiss, E. A.* Nano Lett. 2020, 21, 854– 860. [DOI: 10.1021/acs.nanolett.0c04611] (†equal contribution) 10. Accardo, J. V.; McClure, E. R.; Mosquera, M. A.; Kalow, J. A.* “Using visible light to tune boronic acid–ester equilibria.” J. Am. Chem. Soc. 2020, 142, 19969–19979. [DOI: 10.1021/jacs.0c08551]. [ChemRXiv DOI:10.26434/chemrxiv.12756023] • Highlighted in the December 4 issue of Science, “Dynamic control of boron esters”. 9. Jung, D.; † Das, P.; † Atilgan, A.; Li, P.; Hupp, J. T.; Islamoglu, T.; Kalow, J. A.;* Farha, O. K.* “Reactive porous polymers for detoxification of a chemical warfare agent simulant.” Chem. Mater. 2020, 32, 9299–9306. [DOI: 10.1021/acs.chemmater.0c03160]. (†equal contribution) Julia Kalow: curriculum vitae 3 8. Review: Woods, E. F.;† Berl, A. J.; † Kalow, J. A.* “Advances in the synthesis of π-conjugated polymers by photopolymerization.” ChemPhotoChem 2020. (†equal contribution) [DOI:10.1002/cptc.202000212] 7. Editorial: Bowman, C.; Du Prez, P.; Kalow, J. A. “Introduction to chemistry for covalent adaptable networks.” Polym. Chem. 2020, 11, 5295-5296. [DOI:10.1039/d0py90102d] 6. El-Zaatari, B. M.; Ishibashi, J. S. A.; Kalow, J. A.* “Cross-linker control of vitrimer flow.” Polym. Chem., 2020, 11, 5339–5345. [DOI:10.1039/D0PY00233J] [ChemRXiv DOI: 10.26434/chemrxiv.11464968] • Featured on the back cover. 5. Woods, E. F.; Berl, A. J.; Kalow, J. A.* “Photocontrolled synthesis of n-type conjugated polymers.” Angew. Chem. Int. Ed., 2020, 59, 6062–6067. [DOI:10.1002/anie.201915819] [ChemRXiv DOI:10.26434/chemrxiv.8378405] • Highlighted in ChemistryViews, “Lighting the way to conjugated polymers”. 4. Lin, T.-S.; Coley, C. W.; Mochigase, H.; Beech, H. K.; Wang, W.; Wang, Z.; Woods, E.; Craig, S. L.; Johnson, J. A.; Kalow, J. A.; Jensen, K. F.; Olsen B. D.* “BigSMILES: A structurally-based line notation for describing macromolecules.” ACS Cent. Sci. 2019, 5, 1523–1531. [DOI:10.1021/acscentsci.9b00476] • Highlighted by MIT News, “Notation system allows scientists to communicate polymers more easily”, and in C&EN, “BigSMILES: Machine-readable notation goes polymeric”. • Open source tools at GitHub. 3. Accardo, J. V.; Kalow, J. A.* “Reversibly Tuning Hydrogel Stiffness through Photocontrolled Dynamic Covalent Crosslinks.” Chem. Sci., 2018, 9, 5987–5993. [DOI:10.1039/C8SC02093K] • Highlighted by Associate Editor Luis Campos [link]. 2. Ishibashi, J. S. A.; Kalow, J. A.* “Vitrimeric Silicone Elastomers Enabled by Dynamic Meldrum’s Acid-Derived Crosslinks.” ACS Macro Lett., 2018, 7, 482–486. [DOI:10.1021/acsmacrolett.8b00166] 1. Wang, X.; Kalow, J. A.* “Rapid aqueous photouncaging by red light.” Org. Lett., 2018, 20, 1716–1719. [DOI:10.1021/acs.orglett.8b00100] Mentored research 12. Zarzar, L. D.; Kalow, J. A.; He, X.; Walish, J. J.; Swager, T. M. “Optical Visualization and Quantification of Enzyme Activity using Dynamic Droplet Lenses.” Proc. Natl. Acad. Sci. 2017, 114, 3821–3825. 11. Sha, S.-C.; Zhu, R.; Herbert, M.; Kalow, J. A.; Swager, T. M. “Chemical Warfare Simulant-Responsive Polymer Nanocomposites: Synthesis and Evaluation.” J. Poly. Sci. A Polym. Chem. 2017, 55, 3034–3040. • Invited contribution in honor of Bob Grubbs’ 75th birthday. 10. Nagelberg, S.; Zarzar L. D.; Nicolas, N.; Subramanian, K.; Kalow, J. A.; Sresht, V.; Blankschtein, D.; Barbastathis, G.; Kreysing, M.; Swager, T. M.; Kolle, M. “Reconfigurable and Responsive Droplet-based Compound Micro-Lenses.” Nature Commun. 2017, 8, 14673. 9. Gray, E. E.; Nielsen, M. K.; Choquette, K. A.; Kalow, J. A.; Graham, T. J. A.; Doyle, A. G. “Nucleophilic (Radio)Fluorination of α-Diazocarbonyl Compounds Enabled by Copper-Catalyzed H–F Insertion.” J. Am. Chem. Soc. 2016, 138, 10802–10805. 8. Kalow, J. A.; Swager, T. M. “Synthesis of Miktoarm Branched Conjugated Copolymers by ROMPing In and Out.” ACS Macro Lett. 2015, 4, 1229–1233. Julia Kalow: curriculum vitae 4 7. Zarzar, L. D.; Sresht, V.; Sletten, E. M.; Kalow, J. A.; Blankschtein, D.; Swager, T. M. “Dynamic Reconfiguration of Complex Emulsions via Tunable Interfacial Tensions.” Nature 2015, 518, 520–524. • Featured in Chemical and Engineering News and MIT news. 6. Kalow, J. A.; Doyle, A. G. “34.9.2. b-Fluoro Alcohols (Update 2013).” Sci. Synth. 2013, 4, 417–467. • Invited contribution. 5. Kalow, J. A.; Doyle, A. G. “Enantioselective fluoride ring opening of aziridines enabled by cooperative Lewis acid catalysis.” Tetrahedron 2013, 69, 5702–5709. • Invited paper for Tetrahedron Young Investigator Award Symposium-in-Print in honor of Melanie Sanford. • Highlighted in SYNFACTS (2013, Issue 9). 4. Kalow, J. A.; Schmitt, D. E.; Doyle, A. G. “Synthesis of β-Fluoroamines by Lewis Base Catalyzed Hydrofluorination of Aziridines.” J. Org. Chem. 2012, 77, 4177–4183. 3. Shaw, T. W.; Kalow, J. A.; Doyle, A. G. “Fluoride ring-opening kinetic resolution of terminal epoxides: preparation of (S)-2-fluoro-1-phenylethanol.” Org. Synth. 2012, 89, 9–18. 2. Kalow, J. A.; Doyle, A. G. “Mechanistic investigations of cooperative catalysis in the enantioselective fluorination of epoxides.”