Atlas of Genetics and Cytogenetics in Oncology and Haematology Home Genes Leukemias Solid Tumours Cancer-Prone Deep Insight Portal Teaching X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA Atlas Journal Atlas Journal versus Atlas Database: the accumulation of the issues of the Journal constitutes the body of the Database/Text-Book. TABLE OF CONTENTS Volume 8, Number 3, Jul-Sep 2004 Previous Issue / Next Issue Genes BCAS3 (breast carcinoma amplified sequence 3)(17q23). Jean-Loup Huret, Sylvie Senon. Atlas Genet Cytogenet Oncol Haematol 2004; 8 (3): 367-369. [Full Text] [PDF] URL : http://AtlasGeneticsOncology.org/Genes/BCAS3ID766.html BCAS4 (breast carcinoma amplified sequence 4) (20q13). Jean-Loup Huret, Sylvie Senon. Atlas Genet Cytogenet Oncol Haematol 2004; 8 (3): 370-372. [Full Text] [PDF] URL : http://AtlasGeneticsOncology.org/Genes/BCAS4ID767.html C11ORF30 (chromosome 11 open reading frame 30) (11q13.4). Jean-Loup Huret, Sylvie Senon. Atlas Genet Cytogenet Oncol Haematol 2004; 8 (3): 373-375. [Full Text] [PDF] URL : http://AtlasGeneticsOncology.org/Genes/C11ORF30ID173.html CHEK2 (CHK2 checkpoint homolog (S. pombe)) (22q12.1). Nancy Uhrhammer. Atlas Genet Cytogenet Oncol Haematol 2004; 8 (3): 376-381. [Full Text] [PDF] URL : http://AtlasGeneticsOncology.org/Genes/CHEK2ID312.html LPP (lipoma preferred partner) (3q27-q28). Marleen M Petit. Atlas Genet Cytogenet Oncol Haematol 2004; 8 (3): 382-389. [Full Text] [PDF] URL : http://AtlasGeneticsOncology.org/Genes/LPPID72.html MRE11A (11q21). Nancy Uhrhammer. Atlas Genet Cytogenet Oncol Haematol 2004; 8 (3): 390-395. [Full Text] [PDF] Atlas Genet Cytogenet Oncol Haematol 2004; 3 I URL : http://AtlasGeneticsOncology.org/Genes/MRE11ID247.html OLIG2 (21q22.11). David Rowitch. Atlas Genet Cytogenet Oncol Haematol 2004; 8 (3): 396-399. [Full Text] [PDF] URL : http://AtlasGeneticsOncology.org/Genes/OLIG2ID236.html STAT3 (Signal Transducer and Activator of Transcription 3) (17q21.2). Brent H Cochran. Atlas Genet Cytogenet Oncol Haematol 2004; 8 (3): 400-406. [Full Text] [PDF] URL : http://AtlasGeneticsOncology.org/Genes/STAT3ID444.html TFE3 (transcription factor E3) (Xp11.2) - updated. Roland P Kuiper. Atlas Genet Cytogenet Oncol Haematol 2004; 8 (3): 407-413. [Full Text] [PDF] URL : http://AtlasGeneticsOncology.org/Genes/TFE3ID86.html TFEB (transcription factor EB) (6p21). Roland P Kuiper. Atlas Genet Cytogenet Oncol Haematol 2004; 8 (3): 414-418. [Full Text] [PDF] URL : http://AtlasGeneticsOncology.org/Genes/TFEBID531.html CHFR (Checkpoint with fork-head associated and ring finger) (12q24.33). Ayse E Erson, Elizabeth M Petty. Atlas Genet Cytogenet Oncol Haematol 2004; 8 (3): 419-426. [Full Text] [PDF] URL : http://AtlasGeneticsOncology.org/Genes/CHFRID526.html DIRC1 (2q33). Anita Bonné, Eric Schoenmakers, Ad Geurts van Kessel. Atlas Genet Cytogenet Oncol Haematol 2004; 8 (3): 427-429. [Full Text] [PDF] URL : http://AtlasGeneticsOncology.org/Genes/DIRC1ID499.html FGA7 (Fused Gene 7 to AML1)(4q28). Fady M Mikhail, Giuseppina Nucifora. Atlas Genet Cytogenet Oncol Haematol 2004; 8 (3): 430-433. [Full Text] [PDF] URL : http://AtlasGeneticsOncology.org/Genes/FGA7ID525.html HSPBAP1 (HSPB (heat shock 27kDa) associated protein 1) (3q21.1). Anita Bonné, Eric Schoenmakers, Ad Geurts van Kessel. Atlas Genet Cytogenet Oncol Haematol 2004; 8 (3): 434-437. [Full Text] [PDF] URL : http://AtlasGeneticsOncology.org/Genes/HSPBAP1ID513.html NQO1 (16q22.1) - updated. David Ross. Atlas Genet Cytogenet Oncol Haematol 2004; 8 (3): 438-448. [Full Text] [PDF] URL : http://AtlasGeneticsOncology.org/Genes/NQO1ID375.html Atlas Genet Cytogenet Oncol Haematol 2004; 3 II SERPINB5 (18q21.33). Jim Heighway, Shirley Smith, Naomi Bowers, Daniel Betticher. Atlas Genet Cytogenet Oncol Haematol 2004; 8 (3): 449-459. [Full Text] [PDF] URL : http://AtlasGeneticsOncology.org/Genes/SerpinB5ID42267.html TNF (tumor necrosis factor (TNF superfamily, member 2)) (6p21.3). Fei Chen. Atlas Genet Cytogenet Oncol Haematol 2004; 8 (3): 460-467. [Full Text] [PDF] URL : http://AtlasGeneticsOncology.org/Genes/TNFaID319.html TRC8 (translocation in renal carcinoma, chromosome 8 gene) (8q24.31). Anita Bonné, Eric Schoenmakers, Ad Geurts van Kessel. Atlas Genet Cytogenet Oncol Haematol 2004; 8 (3): 468-471. [Full Text] [PDF] URL : http://AtlasGeneticsOncology.org/Genes/TRC8ID500.html BCL11B (B-cell lymphoma/leukaemia 11B) (14q32.2). Roderick A F MacLeod, Stefan Nagel. Atlas Genet Cytogenet Oncol Haematol 2004; 8 (3): 472-479. [Full Text] [PDF] URL : http://AtlasGeneticsOncology.org/Genes/BCL11BID392.html DDIT3 (DNA damage inducible transcript 3) (12q13.1-q13.2). Pedro A Pérez-Mancera, Isidro Sánchez-Garc&iicute;a. Atlas Genet Cytogenet Oncol Haematol 2004; 8 (3): 480-488. [Full Text] [PDF] URL : http://AtlasGeneticsOncology.org/Genes/DDIT3ID80.html FUS (fusion involved in t(12;16) in malignant liposarcoma) (16p11.2). PA Pérez-Mancera, Isidro Sánchez-García. Atlas Genet Cytogenet Oncol Haematol 2004; 8 (3): 489-498. [Full Text] [PDF] URL : http://AtlasGeneticsOncology.org/Genes/FUSID44.html Smad2, mothers against decapentaplegic homolog 2 (Drosophila) (18q21.1). Raphael Saffroy, Antoinette Lemoine, Brigitte Debuire. Atlas Genet Cytogenet Oncol Haematol 2004; 8 (3): 499-505. [Full Text] [PDF] URL : http://AtlasGeneticsOncology.org/Genes/SMAD2ID370.html Leukaemias t(2;3)(p15-23;q26-27). Marian Stevens-Kroef. Atlas Genet Cytogenet Oncol Haematol 2004; 8 (3): 506-508. [Full Text] [PDF] URL : http://AtlasGeneticsOncology.org/Anomalies/t0203p15q26ID1091.html Multiple myeloma - updated. Franck Viguié. Atlas Genet Cytogenet Oncol Haematol 2004; 8 (3): 509-513. [Full Text] [PDF] URL : http://AtlasGeneticsOncology.org/Anomalies/MMULID2038.html Atlas Genet Cytogenet Oncol Haematol 2004; 3 III Polyclonal B Lymphocytosis with Binucleated Lymphocytes (PPBL). Xavier Troussard, Hossein Mossafa. Atlas Genet Cytogenet Oncol Haematol 2004; 8 (3): 514-517. [Full Text] [PDF] URL : http://AtlasGeneticsOncology.org/Anomalies/PolyclonalLymphoID2040.html +6 or trisomy 6. Edmond SK Ma, Thomas SK Wan. Atlas Genet Cytogenet Oncol Haematol 2004; 8 (3): 518-522. [Full Text] [PDF] URL : http://AtlasGeneticsOncology.org/Anomalies/tri6ID1013.html Solid Tumours Bone: Aneurysmal bone cysts - updated. Paola Dal Cin. Atlas Genet Cytogenet Oncol Haematol 2004; 8 (3): 523-527. [Full Text] [PDF] URL : http://AtlasGeneticsOncology.org/Tumors/AneurBoneCystID5133.html Lung: small cell cancer. Jim Heighway, Daniel C Betticher. Atlas Genet Cytogenet Oncol Haematol 2004; 8 (3): 528-533. [Full Text] [PDF] URL : http://AtlasGeneticsOncology.org/Tumors/LungSmallCellID5142.html Kidney: Clear cell renal cell carcinoma. Eva van den Berg, Stephan Störkel. Atlas Genet Cytogenet Oncol Haematol 2004; 8 (3): 534-540. [Full Text] [PDF] URL : http://AtlasGeneticsOncology.org/Tumors/ClearCellRenalCC5020.html Cancer Prone Diseases Deep Insights Deep insight into microarray technology. Claudia Schoch, Martin Dugas, Wolfgang Kern, Alexander Kohlmann, Susanne Schnittger, Torsten Haferlach. Atlas Genet Cytogenet Oncol Haematol 2004; 8 (3): 541-563. [Full Text] [PDF] URL : http://AtlasGeneticsOncology.org/Deep/MicroarraysID20045.html Case Reports Educational Items © Atlas of Genetics and Cytogenetics in Oncology and Haematology X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA Home Genes Leukemias Solid Tumours Cancer-Prone Deep Insight Portal Teaching For comments and suggestions or contributions, please contact us Atlas Genet Cytogenet Oncol Haematol 2004; 3 IV [email protected]. Atlas Genet Cytogenet Oncol Haematol 2004; 3 V Atlas of Genetics and Cytogenetics in Oncology and Haematology BCAS3 (breast carcinoma amplified sequence 3) Identity Other MAAB names GAOB1 Hugo BCAS3 Location 17q23 DNA/RNA Description spans 715 kb; orientation direct strand; at least 77 exons Transcription alternate splicings: 3.9 kb, 3.3 kb, 2.3 kb, 1.5 kb, 1.3 kb. Protein Expression ubiquitous Localisation nuclear (potential) Implicated in Entity BCAS3 is overexpressed in about 10% of breast cancers, and a hybrid gene BCAS4-BCAS3 was found in breat cancer cell line with a t(17;20)(q23;q13) Hybrid/Mutated 5' BCAS4 is fused to the 2 last exons (23 and 24) of BCAS3; Gene transcript includes exon 1 from BCAS4 and 21 bp from BCAS3 exon 23; it encodes a 66 aminoacids protein; no reciprocal transcript External links Nomenclature Hugo BCAS3 GDB BCAS3 Entrez_Gene BCAS3 54828 breast carcinoma amplified sequence 3 Cards Atlas BCAS3ID766 GeneCards BCAS3 Ensembl BCAS3 CancerGene BCAS3 Genatlas BCAS3 GeneLynx BCAS3 Atlas Genet Cytogenet Oncol Haematol 2004; 3 -367- eGenome BCAS3 euGene 54828 Genomic and cartography BCAS3 - 17q23 chr17:56110015-56824973 + 17q23.2 (hg17- GoldenPath May_2004) Ensembl BCAS3 - 17q23.2 [CytoView] NCBI Genes Cyto Gene Seq [Map View - NCBI] OMIM Disease map [OMIM] HomoloGene BCAS3 Gene and transcription Genbank AF260268 [ SRS ] AF260268 [ ENTREZ ] Genbank AF361219 [ SRS ] AF361219 [ ENTREZ ] Genbank AJ511332 [ SRS ] AJ511332 [ ENTREZ ] Genbank AJ518105 [ SRS ] AJ518105 [ ENTREZ ] Genbank AJ518836 [ SRS ] AJ518836 [ ENTREZ ] RefSeq NM_017679 [ SRS ] NM_017679 [ ENTREZ ] RefSeq NT_086883 [ SRS ] NT_086883 [ ENTREZ ] AceView BCAS3 AceView - NCBI TRASER BCAS3 Traser - Stanford Unigene Hs.463702 [ SRS ] Hs.463702 [ NCBI ] HS463702 [ spliceNest ] Protein : pattern, domain, 3D structure Polymorphism : SNP, mutations, diseases OMIM 607470 [ map ] GENECLINICS 607470 SNP BCAS3 [dbSNP-NCBI] SNP NM_017679 [SNP-NCI] SNP BCAS3 [GeneSNPs - Utah] BCAS3 [SNP - CSHL] BCAS3] [HGBASE - SRS]