ISSN 0110-5566 (Print) ISSN 2624-1161 (Online) Volume 84, No.3, October 2020 Metal-organic frameworks as a platform for transition metal catalysis A review of the impact of anthelmintic resistance on the New Zealand sheep industry: current scenario and potential solution Sentiment analysis: a lens for viewing chemistry narratives Oligonucleotide-based therapeutic agents: challenges and advances Something old, something new: foldamers as catalysts Published on behalf of the New Zealand Institute of Chemistry in January, April, July and October. The New Zealand Institute of Chemistry Printed byGraphic Press Disclaimer Incorporated The views and opinions expressed in Chemistry in PO Box 13798 New Zealand are those of the individual authors and Johnsonville are not necessarily those of the publisher, the Wellington 6440 Editorial Board or the New Zealand Institute of Email: [email protected] Chemistry. Whilst the publisher has taken every Editor precaution to ensure the total accuracy of material Dr Catherine Nicholson contained in Chemistry in New Zealand, no C/- BRANZ, Private Bag 50 908 responsibility for errors or omissions will be Porirua 5240 accepted. Phone: 04 238 1329 Email: [email protected] Copyright The contents of Chemistry in New Zealand are subject to copyright and must not be reproduced in any Publishing Editor form, wholly or in part, without the permission of Raoul Solomon the Publisher and the Editorial Board. Email: [email protected] Advertising Sales Email: [email protected] Volume 84, No.3, October 2020 Articles and features 91 Metal-organic frameworks as a platform for transition metal catalysis Bernhard Auer and Shane G. Telfer 96 A report on the 3rd International Conference on Metal Organic Frame- works and Porous Polymers (EuroMOF 2019) Joel Cornelio 98 A review of the impact of anthelmintic resistance on the New Zealand sheep industry: current scenario and potential solution Arka Gupta, Preet Singh, Catherine Whitby, Bill Pomroy and David RK Harding 105 Sentiment analysis: a lens for viewing chemistry narratives Peter Hodder 119 Oligonucleotide-based therapeutic agents: challenges and advances Harikrishnan M. Kurup* and Vyacheslav V. Filichev 127 Clayton (Ru) Bennett: world class industrial chemist Laurence D. Melton 131 A meeting report on the first nucleic acid chemical biology workshop in New Zealand Vyacheslav V. Filichev, Tracy K. Hale, Elena Harjes and Geoffrey B. Jameson 137 Something old, something new: foldamers as catalysts Suraj Patel and Gareth J. Rowlands 148 NZIC2019 conference report Rebecca Severinsen 150 Atoms and elements Richard Sorrenson Other Columns 82 From the President 152 Author Index 83 October NZIC news 153 Subject Index 136 Obituary for Michael Moore 81 A word from the President Chemistry in New Zealand October 2020 in situ and are very interactive with the ability to include animation, videos and narration. I have been very impressed with Welcome to the October edition of the standard of presentation and the work Chemistry in New Zealand. As there was no that is going on across the Commonwealth July issue, this edition is a bumper one with in support of the UN Sustainable lots of articles. Our new publishing editor Development Goals. It is wonderful to see Raoul Solomon has been working hard on the links being made and to hear feedback the new look for the publication and we hope about the networking that is taking place. I you like it. am delighted that our original representatives from New Zealand, Anna With great sadness Council has accepted the Garden (Otago), Catherine Whitby resignation of our administrator Joanna (Manawatu) and Sangata Kaufononga Dowle. Joanna has worked closely and (Waikato) are all taking part and their tirelessly with the NZIC Council since 2018 posters look awesome! Many and has recently accepted a full time congratulations to Anna Garden who was position elsewhere utilising her chemistry one of the poster prize winners. One of the skills. We are recruiting a replacement and things we were not sure about was the hope to make an announcement soon. In the difference in time zones but the multiple 2hr meantime I want to thank Joanna for all her poster sessions are working well and I have incredible work for NZIC and her support of been able to connect with so many amazing institute, she will be very hard to replace! researchers. I look forward to another event like this in the not too distant future and to I recently presided over my last Council being able to open up participation to a meeting before handing the reins over to broader audience. Michael Mucalo. It was a full meeting and one of the great jobs we had to do was decide our 2020 NZIC prize winners. Many congratulations to Geoffrey Waterhouse (Maurice Wilkins Centre Prize for Chemical Science), Justin Hodgkiss and Kai Chen (Industrial and Applied Chemistry Prize) and Murray Thompson (sciPAD Denis Hogan Chemical Education Award). This year saw applications for the inaugural JEOL Brian Halton Award. This was very well subscribed and I’m delighted to announce that Lynn Lisboa is the recipient. It is very pleasing that the field for these awards was strong and the decisions took a lot of discussion. This is a reflection of the strength and depth of talent in chemistry in New Zealand from the established to early career researchers. Finally this is my last column before stepping Congratulations to all of you. I hope to be down as president of NZIC. I have been very able to connect with you all to present your privileged to hold the term for two years and awards this year. believe that we have achieved a great deal in that time. I am very grateful to those with The NZIC AGM will be held on 30 November whom I have worked closely, and thank at 4.30pm, and this will be held online for everyone on Council and the Chemistry in the first time ever. The aim is to enable New Zealand editorial and publishing team everyone to attend regardless of location for their collegiality and kindness. I look and make the event inclusive for all forward to remaining on Council next year in members. More details will be circulated to the Past President role to support Michael the membership nearer the time. and to seeing NZIC continue to progress and modernise, all the while supporting our The inaugural online poster conference for members. Commonwealth Chemistry is taking place as Sarah Masters this column is typed. This has been a NZIC President fantastic event held online using poster conference technology. Posters are created 82 Chemistry in New Zealand October 2020 October News Notice of NZIC AGM Things”: how do you know that Date: Monday 30 November 2020 the data are re- Venue: Via Zoom video liable? Diarmid Institute commercialisa- conference. Zoom details will be tion manager Kevin Sheehy. sent out to members closer to the NZIC Auckland Branch Seminars time. The University of Auckland hosted Dr Hannah Holtkamp was the following NZIC Auckland awarded the Kelliher Charitable Time: 4:30pm Branch Seminars: Trust Emerging Research Start-up Award, receiving $30,000 towards Dr Courtney Ennis (University of her research costs for her Auck- AUCKLAND Otago): Laboratory simulations of land Medical Research Foundation Titan’s cyanide aerosols. (AMRF) research project. The University of Auckland Dr Love-Ese Chile (Regenerative Dr Muhammad Hanif received an QS Rankings Waste Labs, Vancouver, Cana- AMRF grant to attend the Metals Chemistry at the University of da): Advocacy, education and re- in Medicine Gordon Research Con- Auckland is back in the 101-150 search to build a circular bioecon- ference in Andover, USA. range in the latest QS rankings af- omy for plastics. ter briefly being ranked in the 151- Dr Daniel Furkert and Dame Mar- 200 range last year. The QS rank- Staff Successes garet Brimble received AMRF ing includes research productivity Congratulations to Dr Bruno funding for the project, Antiviral and citations, as well as external Fedrizzi on his Young Scientist therapeutics and development perceptions from peers and em- 2020 award from the Agricultural platform for COVID-19. ployers. and Food chemistry Division of the American Chemical Society. In July, Neuren Pharmaceuticals Our Changing World Bruno’s research in wine extends announced that they had raised James Wright andCameron Weber from studying aroma in New Zea- AUS$20 million to fund clinical tri- were interviewed by Alison Bal- land’s flagship wines to investigat- als of NNZ-2591, the second drug lance for an episode of Our Chang- ing ways to decrease the alcohol candidate developed by the Brim- ing World on the topic of Green content in wine, developing meth- ble group to have reached this Chemistry: ods to measure and modulate the stage. NNZ-2591 is being tested as https://www.rnz.co.nz/national/pro- concentrations of sulfur-contain- a treatment for Phelan-McDermid grammes/ourchangingworld/audio/ ing flavour compounds in wine, syndrome, Angelman syndrome 2018760034/green-chemistry-better- and developing methods to ex- and Pitt Hopkins syndrome, each safer-more-sustainable tract valuable chemicals from of which has orphan drug designa- Nature article grape waste (marc). tion in the United States. The School of Chemical Sciences at the University of Auckland fea- Student Successes tured in an article in Nature on PhD Completions how university research is re- Congratulations to the following starting after COVID-19 lock- students on their successful PhD downs: defences: https://www.nature.com/articles/ d41586-020-01587-z Jinal Patel defended her PhD the- sis, Structural and inhibitor binding School of Chemical Sciences Sem- studies of tyrosyl-DNA phosphodi- inars esterase 1. Jinal was supervised by The School of Chemical Sciences Dr Ivanhoe Leung and co-super- at the University of Auckland has vised by Dr Jóhannes Reynisson continued to host several semi- and Associate Professor Chris nars this year: Squire.