Table S1, SDC. Common deregulated genes between WS and S (L1 vs. L2) S WS Group S Group WS Symbol Entrez Gene Name (Fold- (Fold- (Probesets) (Probesets) change) change) ATP-binding cassette, sub- ABCA1 203504_s_at -1.4 203505_at -1.3 family A (ABC1), member 1 ATP-binding cassette, sub- ABCC4 family C (CFTR/MRP), 203196_at -1.4 203196_at -1.5 member 4 ATP-binding cassette, sub- ABCD3 202850_at -1.4 202850_at -1.2 family D (ALD), member 3 ADCY1 adenylate cyclase 1 (brain) 213245_at -2.0 213245_at -2.1 ADM adrenomedullin 202912_at 2.4 202912_at 2.0 ADORA3 adenosine A3 receptor 206171_at -1.6 206171_at -1.4 ADRB2 adrenoceptor beta 2, surface 206170_at 2.4 206170_at 2.2 argonaute RISC catalytic AGO1 218287_s_at -1.3 218287_s_at -1.3 component 1 anaphase promoting complex ANAPC5 208722_s_at -1.3 211036_x_at -1.3 subunit 5 apolipoprotein L domain APOLD1 221031_s_at 2.8 221031_s_at 3.2 containing 1 AREG amphiregulin 205239_at 4.7 205239_at 4.7 ADP-ribosylation factor ARFGEF2 guanine nucleotide-exchange 218098_at -1.7 218098_at -1.4 factor 2 (brefeldin A-inhibited) ariadne RBR E3 ubiquitin ARIH1 201878_at 1.4 201878_at 1.3 protein ligase 1 ARL2 ADP-ribosylation factor-like 2 202564_x_at -1.2 202564_x_at -1.3 ADP-ribosylation factor-like ARL4C 202207_at 1.5 202207_at 1.7 4C ARMC8 armadillo repeat containing 8 203486_s_at -1.2 203486_s_at -1.3 ARRB1 arrestin, beta 1 43511_s_at -1.2 221861_at -1.1 ATF3 activating transcription factor 3 202672_s_at 11.9 202672_s_at 10.8 ATXN1 ataxin 1 203232_s_at -1.4 203232_s_at-1.5 AVL9 AVL9 homolog (S. cerevisiase) 212474_at -1.5 212474_at -1.4 BAG3 BCL2-associated athanogene 3 217911_s_at 3.3 217911_s_at 3.0 BCL2A1 BCL2-related protein A1 205681_at 4.5 205681_at 2.9 BCL3 B-cell CLL/lymphoma 3 204908_s_at 2.2 204908_s_at 1.8 basic helix-loop-helix family, BHLHE40 201170_s_at 3.0 201170_s_at 2.9 member e40 baculoviral IAP repeat BIRC3 210538_s_at 7.3 210538_s_at 4.6 containing 3 BMP2 bone morphogenetic protein 2 205290_s_at 2.1 205289_at 2.0 BTG2 BTG family, member 2 201236_s_at 2.5 201235_s_at 1.6 BTG3 BTG family, member 3 205548_s_at 1.9 205548_s_at 1.6 chromosome 14 open reading C14orf132 218820_at -1.6 218820_at -1.7 frame 132 carbamoyl-phosphate synthetase 2, aspartate CAD 202715_at -1.2 202715_at -1.5 transcarbamylase, and dihydroorotase CBX5 chromobox homolog 5 212126_at -1.6 212126_at -1.5 coiled-coil domain containing CCDC121 220321_s_at -1.3 220321_s_at -1.3 121 coiled-coil domain containing CCDC93 209688_s_at -1.5 209688_s_at -1.9 93 chemokine (C-C motif) ligand CCL20 205476_at 10.8 205476_at 5.6 20 chemokine (C-C motif) ligand CCL3 205114_s_at 4.5 205114_s_at 5.2 3 chemokine (C-C motif) ligand CCL4 204103_at 7.5 204103_at 7.2 4 CD160 CD160 molecule 207840_at -1.5 207840_at -1.3 CD55 molecule, decay accelerating factor for CD55 201925_s_at 2.2 201925_s_at 1.5 complement (Cromer blood group) CD59 molecule, complement CD59 212463_at -1.3 212463_at -1.4 regulatory protein CD83 CD83 molecule 204440_at 3.0 204440_at 2.6 cyclin-dependent kinase CDKN1A 202284_s_at 2.7 202284_s_at 2.0 inhibitor 1A (p21, Cip1) CCAAT/enhancer binding CEBPB 212501_at 1.5 212501_at 1.4 protein (C/EBP), beta CCAAT/enhancer binding CEBPD 203973_s_at 2.0 203973_s_at 1.9 protein (C/EBP), delta Cbp/p300-interacting transactivator, with Glu/Asp- CITED2 207980_s_at 2.2 207980_s_at 2.9 rich carboxy-terminal domain, 2 CDC28 protein kinase CKS2 204170_s_at 2.7 204170_s_at 3.1 regulatory subunit 2 chloride channel, voltage- CLCN3 201732_s_at -1.5 201735_s_at -1.5 sensitive 3 calmin (calponin-like, CLMN 213839_at -2.4 213839_at -2.4 transmembrane) CLTC clathrin, heavy chain (Hc) 200614_at -1.5 200614_at -1.4 COPB1 coatomer protein complex, 201359_at -1.4 201359_at -1.3 subunit beta 1 CPD carboxypeptidase D 201941_at -1.3 201941_at -1.3 CUL3 cullin 3 201370_s_at -1.4 201371_s_at-1.4 chemokine (C-X-C motif) CXCL1 ligand 1 (melanoma growth 204470_at 4.6 204470_at 2.9 stimulating activity, alpha) chemokine (C-X-C motif) CXCL3 207850_at 5.0 207850_at 3.6 ligand 3 chemokine (C-X-C motif) CXCL8 202859_x_at 12.2 202859_x_at 7.5 ligand 8 chemokine (C-X-C motif) CXCR4 217028_at 2.4 209201_x_at 1.6 receptor 4 cysteine-rich, angiogenic CYR61 201289_at 3.1 201289_at 3.6 inducer, 61 DCP2 decapping mRNA 2 212919_at -1.7 212919_at -2.0 DEAH (Asp-Glu-Ala-His) box DHX32 218198_at -1.2 218198_at -1.2 polypeptide 32 DnaJ (Hsp40) homolog, DNAJB1 200666_s_at 3.8 200666_s_at 4.3 subfamily B, member 1 DPH5 diphthamide biosynthesis 5 222360_at -1.2 219590_x_at -1.2 DUSP10 dual specificity phosphatase 10 215501_s_at 2.0 215501_s_at 2.6 DUSP2 dual specificity phosphatase 2 204794_at 2.1 204794_at 1.8 DUSP3 dual specificity phosphatase 3 201536_at -1.3 201536_at -1.3 DUSP5 dual specificity phosphatase 5 209457_at 3.4 209457_at 4.0 EGR1 early growth response 1 201693_s_at 3.6 201693_s_at 3.6 EGR2 early growth response 2 205249_at 4.6 205249_at 4.5 eukaryotic translation initiation EIF1 212130_x_at 1.3 212227_x_at 1.3 factor 1 E74-like factor 3 (ets domain ELF3 transcription factor, epithelial- 210827_s_at 2.4 210827_s_at 2.2 specific ) elongation factor RNA ELL 204096_s_at 1.2 204096_s_at 1.2 polymerase II elongation factor, RNA ELL2 214446_at 1.7 214446_at 1.5 polymerase II, 2 v-ets avian erythroblastosis ETS2 201329_s_at 2.3 201329_s_at 2.1 virus E26 oncogene homolog 2 family with sequence similarity FAM172A 212936_at -1.7 212936_at -1.7 172, member A family with sequence similarity FAM178A 203482_at -1.5 203482_at -1.5 178, member A family with sequence similarity FAM46A 221766_s_at 2.6 221766_s_at 1.8 46, member A FAM46C family with sequence similarity 220306_at 1.7 220306_at 1.6 46, member C Fanconi anemia, FANCC 205189_s_at -1.4 205189_s_at -1.4 complementation group C FEM1C fem-1 homolog c (C. elegans) 213341_at 1.6 213341_at 1.8 FBJ murine osteosarcoma viral FOS 209189_at 5.6 209189_at 5.5 oncogene homolog FOSL2 FOS-like antigen 2 218880_at 2.8 218880_at 2.5 FZD4 frizzled class receptor 4 218665_at -1.5 218665_at -1.3 growth arrest and DNA- GADD45A 203725_at 1.9 203725_at 1.7 damage-inducible, alpha growth arrest and DNA- GADD45B 209305_s_at 4.4 209305_s_at 4.5 damage-inducible, beta polypeptide N- GALNT10 acetylgalactosaminyltransferase 212256_at -1.4 207357_s_at -1.2 10 glutamate-cysteine ligase, GCLM 203925_at 1.2 203925_at 1.3 modifier subunit GCN1 general control of GCN1L1 amino-acid synthesis 1-like 1 212139_at -1.5 212139_at -1.5 (yeast) golgi-associated, gamma GGA2 adaptin ear containing, ARF 208914_at -1.4 208914_at -1.3 binding protein 2 GLUL glutamate-ammonia ligase 200648_s_at1.5 200648_s_at1.5 GPR183 G protein-coupled receptor 183 205419_at 3.3 205419_at 2.8 glycosyltransferase-like GTDC1 219770_at -1.2 219770_at -1.2 domain containing 1 granzyme B (granzyme 2, GZMB cytotoxic T-lymphocyte- 210164_at 1.8 210164_at 1.7 associated serine esterase 1) granzyme K (granzyme 3; GZMK 206666_at -1.6 206666_at -1.3 tryptase II) HBA1/HBA2 hemoglobin, alpha 1 217414_x_at 2.4 217414_x_at 2.7 heparin-binding EGF-like HBEGF 203821_at 2.5 203821_at 2.2 growth factor hydroxycarboxylic acid HCAR3 205220_at 3.3 205220_at 2.8 receptor 3 HDAC4 histone deacetylase 4 204225_at -1.3 204225_at -1.7 hypoxia inducible lipid droplet- HILPDA 218507_at 1.6 218507_at 1.4 associated HSPA1A/HSPA1B heat shock 70kDa protein 1A 202581_at 12.6 202581_at 11.4 heat shock 105kDa/110kDa HSPH1 206976_s_at 2.7 208744_x_at 2.4 protein 1 HTT huntingtin 202389_s_at -1.2 202390_s_at-1.2 ICAM1 intercellular adhesion molecule 202638_s_at4.5 202638_s_at3.1 1 IER2 immediate early response 2 202081_at 2.9 202081_at 2.1 IER3 immediate early response 3 201631_s_at 3.5 201631_s_at 2.2 IER5 immediate early response 5 218611_at 2.6 218611_at 2.1 IL1B interleukin 1, beta 39402_at 3.3 39402_at 3.1 interleukin 1 receptor IL1RN 212657_s_at 5.4 212657_s_at 5.0 antagonist IL6 interleukin 6 205207_at 2.8 205207_at 2.0 INHBA inhibin, beta A 210511_s_at 1.5 210511_s_at 1.5 IPO5 importin 5 211954_s_at -1.5 211954_s_at-1.4 inositol-trisphosphate 3-kinase ITPKC 213076_at 1.9 213076_at 1.4 C influenza virus NS1A binding IVNS1ABP 206245_s_at 1.6 206245_s_at 1.8 protein JMJD6 jumonji domain containing 6 212723_at 1.8 212722_s_at 1.6 JUN jun proto-oncogene 201466_s_at 5.4 201466_s_at6.1 JUNB jun B proto-oncogene 201473_at 2.5 201473_at 2.1 JUND jun D proto-oncogene 203752_s_at 2.8 203752_s_at 3.4 potassium voltage-gated KCNE4 channel, Isk-related family, 222379_at 2.1 222379_at 1.6 member 4 KH and NYN domain KHNYN 212356_at -1.4 212356_at -1.6 containing KIAA0100 KIAA0100 201729_s_at -1.8 201728_s_at-1.5 KLF2 Kruppel-like factor 2 219371_s_at 2.3 219371_s_at 2.2 KLF4 Kruppel-like factor 4 (gut) 221841_s_at 3.4 221841_s_at 3.1 KLF6 Kruppel-like factor 6 208961_s_at 4.0 208961_s_at 4.6 KLF9 Kruppel-like factor 9 203542_s_at 1.6 203542_s_at 1.7 KLHDC10 kelch domain containing 10 209256_s_at -1.8 209256_s_at -1.5 Kirsten rat sarcoma viral KRAS 214352_s_at 1.3 214352_s_at 1.3 oncogene homolog lymphocyte cytosolic protein 2 LCP2 (SH2 domain containing 205269_at 1.7 205270_s_at 1.3 leukocyte protein of 76kDa) long intergenic non-protein LINC00341 219563_at -1.9 219563_at -2.1 coding RNA 341 LOC102724428/SIK1 salt-inducible kinase 1 208078_s_at 3.4 208078_s_at 4.2 uncharacterized LOC103344931 213739_at -1.2 213739_at -1.3 LOC103344931 leucine-rich pentatricopeptide LRPPRC 211615_s_at -1.3 211615_s_at -1.3 repeat containing LRRC37A3 (includes leucine rich repeat containing 221740_x_at -1.4 221740_x_at -1.6 others) 37, member A3 MAFF v-maf avian 36711_at 8.0 36711_at 5.0 musculoaponeurotic fibrosarcoma oncogene homolog