FINE & SPECIALTY CHEMICALS 1/ 2019 I N © Maksym Yemelyanov - stock.adobe.com Yemelyanov © Maksym Markets & Companies Strategy & Management Technology & Innovation M&A: Asian Investment in Chemicals in Circular Economy, Flow Chemistry and Micro European Chemical Companies, Surfactants in Solutions and at Reaction Technology, Image Global Biologics CDMO Market, Interfaces, Price Erosion for Processing in Quality Control, Company News Biosimilars Threatens Companies Digital Chemical Sales 34th International Exhibition for Fine and Speciality Chemicals 26 – 27 June 2019 | Messe Basel, Switzerland Fine and speciality chemicals for various industries Europe’s most renowned industry hotspot Meet suppliers and experts from around the globe and find bespoke solutions, new approaches and innovative substances for your enterprise. fine chemicals • agrochemicals • pharmaceuticals • adhesives & sealants • paints & coatings colourants & dyestuffs • flavours & fragrances • pulp & paper chemicals household & industrial cleaning • leather & textile plastics additives • food & feed ingredients cosmetics • polymers • surfactants water treatment • petrochemicals electronic chemicals and much more Top conferences • Agrochemical Lecture Theatre and workshops offer • Chemspec Careers Clinic • Pharma Lecture Theatre valuable insights • Regulatory Services Lecture Theatre into ongoing • RSC Lecture Theatre R&D projects! • Innovative Start-ups www.chemspeceurope.com Organisers: C ONTENT ©Bits and Splits - stock.adobe.com TECHNOLOGY & INNOVATION Cheaper, Faster, Smaller, Cleaner 18 Prospects of Flow Chemistry for Fine & Specialty Chemicals and Pharma ©manop1984 - stock.adobe.com Volker Oestreich, CHEManager Flow Chemistry: Key Technology for Sustainable Processes 20 Experts Discuss Challenges and Opportunities MARKETS & COMPANIES of Micro Reaction Technologies Experts of BASF, Clariant, Ehrfeld Mikrotechnik, Asian Interest in European Chemical Firms 4 ©alphaspirit - stock.adobe.com Innosyn, Microinnova, Patheon, Sanofi, Syrris, Chemical M&A Buoyant after a Record Year in Asia and Università di Perugia share their opinions Bernd Schneider, Alantra Chemical Sales Going Digital: What to Expect? 23 The Missing Piece 6 STRATEGY & MANAGEMENT Are the New Digital and Global Opportunities in Chemicals in Circular Economy Chemicals more Threat or Possibility? Anne-Sofie Bäckar, ChemSec The R&D Footprint of the Chemical Industry 13 Alexander Lakemeyer, Pinpools Chemical R&D Spending Generates Long-Term Benefits A Better Way to Use Resources 8 for Society at Large Analyzing Pores Deep-Down 24 At Nouryon, Circular Projects Are Linked to Quality Control of Porous or Granular Substances Improving the Existing Value Chain The Need for Innovation in with Modern Image Processing Interview with Marco Waas, Nouryon Pharmaceutical Manufacturing 14 Daniel Balser, Strelen Single-Use Technologies and IIoT Solutions in Imagine Chemistry 2019 Generates 162 Ideas 9 Biopharmaceuticals Manufacturing Unmesh Lal, Frost & Sullivan Solving Challenges at Interfaces 10 EVENTS 26 Surfactants are used in a Variety of Biosimilars: The Price Challenge 16 Applications from Detergents to Cosmetics to Market Prices Have Come Down Significantly – IMPRINT 26 Crop Protection to Oil & Gas How Much Can Copycat Makers Really Earn? Staffan Asplund, CESIO Thorsten Schüller, CHEManager INDEX 26 Cover Page Periodic Table of Chemical Elements turns 150 The Periodic Table of Elements is anniversary, 2019 has been desig­ Qi­Feng Zhou, IUPAC president, mistry and show creative ideas on one of the most significant achie­ nated by UNESCO as the Internatio­ calls the periodic table “a map of this topic. The cover page of this vements in science. 150 years ago, nal Year of the Periodic Table (IYPT our knowledge, particularly in che­ edition of CHEManager Internatio­ Russian chemist and inventor Dmitri 2019). mistry, and a symbolic representa­ nal shows the periodic table to re­ Ivanovich Mendeleev created his far­ The discovery of the “periodic tion of the process of scientific re­ cognize its importance for gene­ sighted version of the periodic table. law” by Mendeleev and the creation search.” rations of chemical researchers. He used it to correct the properties of the tabular display of the chemi­ ChemPubSoc Europe, a part­ Without Mendeleev’s invention 150 of some already discovered elements cal elements in order of increasing nership of 16 continental Euro­ years ago, science would have ta­ and to predict the properties of eight atomic number has since been of pean chem ical societies, and Chem­ ken a different route or at least a elements yet to be discovered. ines timable value in the develop­ istryViews.org are highlighting the detour and many discoveries that The year 2019 marks the celeb­ ment of chemistry. Naming them all 150th anniversary of the 150th an­ have led to innovation and pro­ ration of the 150th anniversary of the would go beyond the scope of this niversary of the periodic table to gress would probably have never periodic table. On the occasion of this note. raise global awareness of che­ been made. (mr) CHEManager | Fine & Specialty Chemicals 3 M ARKETS & C O M PA N I E S Asian Interest in European Chemical Firms Chemical M&A Buoyant after a Record Year in Asia The chemical industry is one of the most international sectors with slowed down in the fourth quar­ activity dominated by cross border transactions. Chinese and other ter, but the first nine months saw 23 trans actions of which, for ex­ Asian firms have been particularly busy expanding their global foot- ample, ten in the consumer or a res­ print and taking advantage of the quality assets for sale. pective seven in the business services and energy, mining and utilities sec­ tors. By contrast, transactions in the US plummeted 94.6% to $3 billion Bernd Schneider, Worldwide, geopolitical tensions trade wars with the US caused a dra­ last year from a record $55.3 billion Alantra and slowing global economic growth matic shift in deal flow. Europe be­ in 2016, according to Mergermarket took its toll in terms of the number came the preferred destination with figures. of deals, according to Mergermarket The motives behind European presence in the plastics industry data for fiscal year (FY) 2018. How­ transactions are the same as those beyond chemicals trading and fertili­ ever, deal volumes jumped 11.5% to driving other global purchases — zer production. $3.53 trillion in 2018 compared to “Chinese and other Asian to close the gap through acquiring the prior year while more specifically firms have been particularly technological prowess as well as ex­ the Asia­Pacific (excl. Japan) M&A busy expanding their global pertise, proprietary formulations Growing Investment Interest region recorded 4,036 deals totaling footprint and taking and products. One example is the in Sustainable Industries $717.4 billion, a 2.6% hike over 2017. roughly €200 million sale of Euro­ Overall, the industrials and chem­ advantage of the quality pean engineering plastics specialist It has been well documented that icals sector was the most attractive assets for sale.” Elix Polymers by Sun European Part­ the Chinese economy is slowing to sector in 2018 by both value and vo­ ners to Beijing­based Sinochem. The 6% growth from an originally fore­ lume. The final tally was 318 deals deal supports the ABS Compound casted 6.5%, but growth is still re­ priced at $68 billion, compared to producer’s strategy to expand its ac­ latively robust compared to the low $82 billion across 321 deals in 2017. Chinese acquisitions in the region tivities in Asia, a region in which it is single growth figures of many deve­ China continued to be an active surging 81.7% to $60.4 billion from currently underrepresented. At the loped countries. Chinese companies participant although the on going $33.2 billion in 2017. Deal making same time, it will boost Sinochem’s will continue to look for opportunities ©manop1984 - stock.adobe.com 4 CHEManager | Fine & Specialty Chemicals M ARKETS & C O M PA N I E S in traditional chemical segments, but ger a wave of restructuring resulting stock market. Medium­sized com­ Bernd Schneider, managing di- they are also interested in buying or­ in new strategic plans and the hiving panies in the US and Europe such rector and global head of Chem- ganizations involved in pollution, wa­ off of subsidiaries. Specialists and as the German Mittelstand would icals, Alantra, Frankfurt am Main, ter and waste treatment solutions as niche companies would be particu­ be especially interested in them be­ Germany well as green and sustainable chemi­ larly attractive not only due to their cause many missed out on getting a cals and plastics. sharper competitive edge and tech­ foothold in the Chinese market due This is being driven by the nological expertise but also lower to increasing prices during the first [email protected] government’s new environmentally­ valuations on the back of a weaker wave of M&A activity. www.alantra.com friendly laws under the 12th Five­ Year Plan which aims to clamp down on unsustainable industries and in­ centivize clean and green energy businesses. Chinese Government Influence Your wish our goal We are a dedicated custom manufacturer for hazardous chemical reactions While the flow of deals has mainly been from China to the West, the such as Nitration and Phosgenation (COCl2). Our team of experts looks tide has not been just one way: Glo­ forward to helping you in all your needs for chemical intermediates and APIs. bal conglomerates