PROGRAM AND PAPERS ON NEW RESEARCH IN SUMMARY FORM THE ONE HUNDRED AND FORTY-SECOND ANNUAL MEETING OF THE AMERICAN PSYCHIATRIC ASSOCIATION SAN FRANCISCO, CALIFORNIA May 6-11, 1989 Papers presented at New Research Sessions are not automatically the property of the American Journal of Psychiatry. Authors are free to submit them to the Ameri­ can Journal of Psychiatry, Hospital & Community Psychiatry, or another publication of their choice. SUBCOMMITTEE ON NEW RESEARCH OF THE SCIENTIFIC PROGRAM COMMITTEE Allan Tasman, M.D. Farmington, CT Charles A. Kaufmann, M.D. Peter S. Jensen, M.D. John Markowitz, M.D. New York, NY Fort Gordon, GA New York, NY John Morihisa, M.D. Susan Fiester, M.D. Arnold Werner, M.D. Washington, DC Nashua, NH East Lansing, MI Outside Reviewers for New Research Program Hagop S. Akiskal, M.D. Charles P. O'Brien, M.D. Nancy C. Andreasen, M.D. John M. Oldham, M.D. Jack D. Barchas, M.D. Davia Pickar, M.D. Wade H. Berrenttini, M.D. Robert M. Post, M.D. Richard L. Borison, M.D. William Z. Potter, M.D. Gabrielle A. Carlson, M.D. Joachim Puig-Antich, M.D. Joseph T. Coyle, M.D. Fred M. Quitkin, M.D. Raymond R. Crowe, M.D. Murray A. Raskind, M.D. Glen C. Davis, M.D. Stephen G. Rayport, M.D. Marshal F. Folstein, M.D. Elliott Richelson, M.D. Arnold J. Friedhoff, M.D. Peter P. Roy-Byrne, M.D. Abby J. Fyer, M.D. A. John Rush, M.D. Elliott S. Gershon, M.D. Michael H. Sacks, M.D. Ira D. Glick, M.D. Charles A. Shamoian, M.D. Judith H. Gold, M.D. Larry J. Siever, M.D. Jack M. Gorman, M.D. Jonathan M. Silver, M.D. Igor Grant, M.D. Andrew E. Skodol, M.D. Katherine A. Halmi, M.D. Robert L. Spitzer, M.D. Dilip V. Jeste, M.D. Michael J. Stanley, M.D. John. M. Kane, M.D. Marvin Stein, M.D. Frederick I. Kass, M.D. James J. Strain, M.D. Herbert D. Kleber, M.D. Trey Sunderland, M.D. Donald F. Klein, M.D. Kenneth J. Tardiff, M.D. Joel E. Kleinman, M.D. Gary J. Tucker, M.D. Donald S. Kornfeld, M.D. Joe P. Tupin, M.D. David J. Kupfer, M.D. Thomas W. Uhde, M.D. Michael D. Liebowitz, M.D. Fred Vokmar, M.D. Markku V. Linnoila, M.D. B. Timothy Walsh, M.D. Herbert V. Meltzer, M.D. Daniel R. Weinberger, M.D. John M. Morihisa, M.D. George E. Woody, M.D. Charles B. Nemeroff, M.D. Stuart C. Yudofsky, M.D. Monday, May 8, 1989, 9:00 a.m.-10:30 a.m. New Research 1-Poster Session-Yosemite Room, Ballroom Level, Hilton YOUNG INVESTIGATORS' POSTER SESSION Moderator: Harold Alan Pincus, M.D. NR1 Abuse and Self-Injury in Adolescent Inpatients Timothy G. Lesaca, M.D. NR2 Ventricle-Brain Ratio in Schizophrenia: Clinical Correlations John R. Dequardo, M.D., Raymond Kloss, M.D., Rajiv Tandon, M.D. NR3 Trait Anxiety and Psychomotor Activity Duncan Clark, M.D., Roy King, M.D., Jurgen Margraf, Ph.D., Walton T. Roth, M.D., Stewart Agras, M.D., C. Barr Taylor, M.D. NR4 Anticholinergics and Cardiac Function During ECT Shashidhar M. Shettar, M.D., Leon Grunhaus, M.D., Atul C. Pande, M.D., Rajiv Tandon, M.D., Ziad Kronfol, M.D. NR5 Relationship Between Sleep EEG Measures and ECT Seizure Length Shashidhar M. Shettar, M.D., James E. Shipley, M.D., Leon Grunhaus, M.D., Roger F. Haskett, M.D., Alan S. Eiser, Ph.D. NR6 Spread of Cocaine Among Adults and Adolescents John E. Hickey, L.C.S.W., Anne F. Kolar, M.D., Barry S. Michaelson, M.A., Anneke Chung, B.A., Carolyn Haynie, M.D., Barry S. Brown, Ph.D. NR7 Cocaine: Perceived, Risk and Sources of Information John E. Hickey, L.C.S.W., Barry S. Brown, Ph.D., Anne S. Chung, B.A., Anne F. Kilar, M.D., Barry S. Michaelson, M.A. NR8 Age and the Prevalence of Dissociation Robert W. Hermanowski, 8.S., Moshe S. Torem, M.D., Kathryn J. Curdue, M.D. NR9 Profile of Dropouts and Attenders in a Family Support Group Mary L. De Florio, M.D., Stephen A. Cole, M.D., Samuel Simmens, Ph.D., Robert Shapiro, Ph.D., Stuart Barr, M.D., Danny Wu, M.D. NR10 Negative Symptom Assessment in Schizophrenia Raman Sood, M.D., Rodney J. Pelchat, M.D., Larry D. Alphs, M.D., Jerome Levine, M.D., Harini Balu, M.D., Allen Raskin, Ph.D. NR11 Comparison of Negative Symptom Scale Jose de Leon, M.D., George M. Simpson, M.D., William H. Wilson, M.D. NR12 CCRT: A Method for Comparing Neurotics and Borderline Ellen K .. Schiefer, M.D., Michael A. Selzer, M.D., John Clarkin, Ph.D., Frank Yeomans, M.D., Lester Lubarsky, M.D. NR13 Serotonin Probes in Obsessive Compulsive Disorder Teresa A. Pigott, M.D., Dennis L. Murphy, M.D., Michele T. Pato, M.D., James L. Hill, Ph.D., Gay Grover, M.S.N., Chawki Benkelfat, M.D. 1 NR14 Clomipramine Versus Buspirone in OCD: A Controlled Trial Michele T. Pato, M.D., Teresa A. Pigott, M.D., James L. Hill, Ph.D., Gay Grover, M.S.N., Suzanne E. Bernstein, B.S., Dennis L. Murhpy, M.D. NR15 Somatostatin in Alzheimer's Disease Susan E. Molchan, M.D., David R. Rubinow, M.D., Brian A. Lawlor, M.D., Rick A. Martinez, M.D., James L. Hill, Ph.D., Alan M. Mellow, M.D., Trey Sunderland, M.D. NR16 The Impact of Locked Units on Seclusion Practices Michael J. Sedlacek, M.D., William J. Burke, M.D., Steven Wengel, M.D. NR17 The DST: Refinement of Predictive Value Scott B. Patten, M.D. NR18 Effect of Vasopressin and Naloxone on Cortisol E. Jane Garland, M.D., A. P. Zis, M.D. NR19 Metabolic Rates in OCD and Comprisons with Panic Disorders Thomas E. Nordahl, M.D., Chawki Benkelfat, M.D., William E. Semple, Ph.D., Murray B. Stein, M.D., Thomas A. Mellman, M.D., Michael Gross, M.D., Thomas W. Uhde, M.D., Robert M. Cohen, M.D. NR20 5-HT Function in the Biochemical Response to MCPP John P. Selbyl, M.D., Dennis S. Charney, M.D., John H. Krystal, M.D., Lawrence H. Price, M.D., George R. Heninger, M.D. NR21 Do Mast and Cage Scores Help Detect Alcoholism? Connie M. Marsh, M.D., Donna A. Vaughan, M.D. NR22 Long-Staying Inpatients: A Descriptive Study Terry M. Brown, D.O., Robert N. Golden, M.D., David Ekstrom, M.Ph., Helen L. Miller, M.D., Dwight L. Evans, M.D. NR23 Cognitive Impairment in Tardive Dyskinesia Michael F. Egan, M.D., James Gold, Ph.D., Terry Goldberg, Ph.D., Darrell G. Kirch, M.D., David G. Daniel, M.D., Richard Jed Wyatt, M.D., Daniel R. Weinberger, M.D. NR24 DSPECT in Obsessive Compulsive Disorder John R. Debus, M.D., Michael D. Devous, Ph.D., John W. Cain, M.D., John Battaglia, M.D., S. Nadeem Ahmed, M.D., A. John Rush, M.D. NR25 Effect of Weight Loss on Brain Neuropeptide mRNAs Mark A. Smith, M.D., Linda S. Brady, Ph.D., Philip W. Gold, M.D. NR26 Psychiatry Resident Identification in a Strike Robert Kohn, M.D., Ronald M. Wintrob, M.D. NR27 Anti-HLA Antibodies and Chlorpromazine Robert C. Alexander, M.D., Mark A. Coggiano, M.S., Richard Jed Wyatt, M.D. NR28 Brain Structure and Function in Schizophrenia Ana Maria Andia, M.D., Julie Kuck, M.A. NR29 Ventricular Brain Ratios in Dementia: Depression and Controls Rick A. Martinez, M.D., Susan E. Molchan, M.D.,James L. Hill, Ph.D., Brian A. Lawlor, M.D., David Rubinow, M.D., Trey Sunderland, M.D. NR30 Stimulant/Haldol Study of SPEM CPT and P50 in Normals Dolores Malaspina, M.D., Edward Maclin, Ph.D., Barbara Cornblatt, Ph.D., Eliza A. Coleman, B.A, Harold Sackeim, Ph.D.,. Charles A. Kaufmann, M.D. 2 NR31 Substance Abuse in Borderline Personality Disorder Rebecca A. Dulit, M.D., Minna Fyer, M.D., Timothy Sullivan, M.D., Allen J. Frances, M.D. NR32 AIDS Knowledge and Attitudes in Psychiatric Staff Carol L. Alter, M.D., Gregory Miller, M.D., Ellen Dickinson, M.D. NR33 Effects of Different Light Wavelengths in SAD Dan A. Oren, M.D., George C. Brainard, Ph.D., Jean R. Joseph-Vanderpool, M.D., Elizabeth Sorek, R.N., Scott Johnston, B.A., Norman E. Rosenthal, M.D. NR34 Deep White Matter Hyperintensity on MRI Raymond F. Deicken, M.D., Victor I. Reus, M.D., Luisa Manfredi, B.A., Owen M. Wolkowitz, M.D. NR35 Changes in Cerebral Laterality with the Menstrual Cycle Margaret Altemus, M.D., Bruce Wexler, M.D., Glenna King, B.A. NR36 Comparison of Symptoms in OCD and Tourette's Kathy J. Tobias-Smith, M.D., David L. Pauls, Ph.D. NR37 Structural Changes in Astrocytes in an Experimental Model of Temporal Lobe Epilepsy Aldo Joseph Castiglioni Jr., M.D., Steve Peterson, Ph.D., Evelyn Tiffany-Castiglioni, Ph.D. NR38 Alcoholism and CSF IgG Synthesis in HIV Seropositive Men Karen P.G. Drexler, M.D., James Rundell, M.D., George Brown, M.D., Susan Paolucci, M.D., Joseph Pace, M.D., Susan McManis, M.D. NR39 Irritability and Apathy in Huntington's Disease Carol E. Peyser, M.D., Marshal F. Folstein, M.D., Sergio E. Starkstein, M.D., Susan E. Folstein, M.D. NR40 Fluoxetine Induced Mania David E. Hon, M.D., Sheldon H. Preskorn, M.D. NR41 Abuse, Dissociation and PTSD in LLPDD Patients Margaret F.