Oversight Committee Meeting February 15, 2017 Summary Overview of the February 15, 2017, Oversight Committee Meeting This summary provides an overview of major agenda items and background on key issues for Committee consideration at the February 15, 2017, Oversight Committee meeting. CEO Report Wayne Roberts will present the CEO’s report and address issues including a personnel update, including a discussion of Governor Abbott’s freeze on state agency hiring, action items from the November 16th Oversight Committee meeting, the FY 2016 annual report, a legislative update, and report on FY 2017 grant award funds available. Mr. Roberts will also present his annual report required by Tex. Health & Safety Code § 102.260(c). Chief Compliance Officer Report Vince Burgess will report on the status of required grantee reports, financial status report reviews, annual grantee certifications, desk reviews and site visits as well as grantee training and technical assistance. Chief Scientific Officer Report and Grant Award Recommendations Dr. James Willson will provide an update on the Academic Research Program and present the Program Integration Committee’s five award recommendations for Recruitment of Established Investigators and First-Time, Tenure-Track Faculty recruitment grants totaling $22 million. Dr. Willson will also present the PIC’s recommendation increasing the grant award amount previously approved by the Oversight Committee for CPRIT grant RP170259. CPRIT will not publicly disclose information related to the Academic Research grant applications recommended for funding until the Oversight Committee meeting. The information is available to board members through a secure electronic portal. Chief Prevention and Communications Officer and Grant Award Recommendations Dr. Becky Garcia will update the Oversight Committee on the Prevention Program activities as well as an update on the agency’s communications activities. She will present the Program Integration Committee’s nine award recommendations totaling $12,024,696. CPRIT will not publicly disclose information related to the Prevention Program grant applications recommended for funding until the Oversight Committee meeting. The information is available to board members through a secure electronic portal. Chief Product Development Officer Report Mr. Mike Lang will provide an update on the Product Development Program. He will also present proposed policy changes to the standard revenue sharing terms and matching fund requirements for grantees receiving a second award. Information regarding proposed contract February 15, 2017, Oversight Committee Meeting Overview Summary Page 2 amendments have been provided under separate cover and will be discussed in closed session with CPRIT’s General Counsel. Appointments - Scientific Research and Prevention Programs Committee and Advisory Committee on Childhood Cancers The Chief Executive Officer has provisionally appointed two new members to CPRIT’s Scientific Research and Prevention Programs Committees. CPRIT’s statute requires the Oversight Committee to approve the CEO’s recommendations before the appointment is final. Biographical sketches for the appointees are included in the board packet. In addition, Mr. Roberts has provisionally appointed 12 new members of the Advisory Committee on Childhood Cancer. Internal Auditor Report Weaver and Tidwell, CPRIT’s internal auditor, will provide an internal audit update. Advisory Committee Reports Both the University Advisory Committee and Advisory Committee on Childhood Cancers will present their annual reports to the Oversight Committee. The committees’ charters require each to provide updates to the Oversight Committee annually. Amendments to 25 TAC Chapters 701 - 703 Ms. Doyle will present the final order approving two amendments to Chapter 703 that the Oversight Committee provisionally approved at the November meeting. If approved, the amendments will become effective in March. Ms. Doyle will also present six proposed changes to the agency’s administrative rules. Texas Health and Safety Code § 102.108 authorizes the Oversight Committee to implement rules to administer CPRIT’s statute. Legal staff will bring back these rule changes to the Oversight Committee for final approval in May after the public has an opportunity to comment on the proposed rule changes. Chief Operating Officer Report Heidi McConnell will discuss the operating budget, performance measures, and debt issuance history for the first quarter of FY 2017. Subcommittee Business Presiding Officer Geren will present his recommendation for new members of the Prevention Program Subcommittee and for new chairs of the Audit Subcommittee Chair and Prevention Program Subcommittee. 2 Oversight Committee Meeting Agenda Texas Higher Education Coordinating Board 1200 E. Anderson Lane, Austin, TX 78752 Board Room 1.170 February 15, 2017 11:00 a.m. The Oversight Committee may discuss or take action regarding any item on this agenda, and as authorized by the Texas Open Meetings Act, Texas Government Code Section 551.001 et seq., may meet in closed session concerning any purpose permitted by the Act. Anyone wishing to offer public comments must notify the Chief Executive Officer in writing prior to the start of the meeting. The Committee may limit the time a member of the public may speak. 1. Call to Order 2. Roll Call/Excused Absences 3. Adoption of Minutes from the November 17, 2016 meeting TAB 1 4. Public Comment 5. Grantee Presentations TAB 2 6. Chief Executive Officer Report TAB 3 CEO Report Pursuant to Health & Safety Code § 102.260(c) 7. Chief Compliance Officer Report TAB 4 8. Chief Scientific Officer Report and Grant Award Recommendations TAB 5 RP170259 Contract Amendment 9. Chief Prevention and Communications Officer Report and Grant Award TAB 6 Recommendations 10. Chief Product Development Officer Report TAB 7 Standard Revenue Sharing Terms Matching Requirements for Second Awards RP110508/DP160057 Contract Amendment CP120038 Contract Amendment RP101219/DP140067 Contract Amendment 11. Scientific Research and Prevention Program Committee Appointments TAB 8 12. Advisory Committee on Childhood Cancers Appointments TAB 9 13. Internal Auditor Report TAB 10 14. Advisory Committee on Childhood Cancers – Annual Report TAB 11 15. University Advisory Committee – Annual Report TAB 12 16. Amendments to 25 T.A.C. Chapters 701 and 703 TAB 13 Final Order Approving Amendments to Chapter 703 Proposed Amendments to Chapters 701 and 703 and Authorization to Publish in Texas Register 17. Chief Operating Officer Report TAB 14 18. Subcommittee Business 19. Compliance Investigation Pursuant to Health & Safety Code § 102.2631 20. Consultation with General Counsel 21. Future Meeting Dates and Agenda Items TAB 15 22. Adjourn Oversight Committee Meeting November 16, 2016 1. Call to Order A quorum being present, Presiding Officer Geren called the Oversight Committee to order at 10:02 a.m. 2. Roll Call/Excused Absences Committee Members Present: Angelos Angelou Pete Geren Donald (Dee) Margo Amy Mitchell Bill Rice, M.D. Craig Rosenfeld, M.D. Ned Holmes Cynthia Mulrow, M.D. Committee Members Absent: Will Montgomery MOTION: On a motion made by Mr. Holmes and seconded by Ms. Mitchell, the Oversight Committee unanimously voted to excuse the absence of Mr. Montgomery. 3. Adoption of Minutes from August 17, 2016 and September 14, 2016 meetings MOTION: On a motion made by Dr. Mulrow and seconded by Mr. Margo, the Oversight Committee unanimously voted to approve the minutes of the Oversight Committee meetings held on August 17, 2016, and September 14, 2016. 4. Public Comment Presiding Officer Geren noted there are no requests for public comment. 1-1 5. Grantee Presentation Presiding Officer Geren noted that grantee presentations will become a regular part of CPRIT Oversight Committee meetings. He called on Dr. James Willson, Chief Scientific Officer, to introduce Dr. Thomas Yankeelov. Dr. Willson introduced CPRIT Grantee Dr. Thomas Yankeelov, Professor at The University of Texas at Austin, Biomedical Engineering Department. Dr. Yankeelov is a CPRIT grantee recruited to The University of Texas as an established investigator in December 2015. He is leader of the Strong Institute’s Cancer Research Program and also Director of the Computational Oncology Program in the Texas Institute of Computational Engineering and Science. His research focus is on using computational biology, advanced in vivo imaging, and mathematical modeling. His clinical research has an overall goal of improving patient care by employing advanced imaging methods for the early identification, assessment, and prediction of tumor response to therapy. He develops tumor forecasting methods by integrating advanced imaging technologies with patient-specific data and builds predictive, multi-scale biophysical models of tumor growth with the purpose of optimizing therapies for the individual cancer patient. Dr. Yankeelov summarized his research to develop tumor forecasting methods by integrating advanced imaging technologies with other patient-specific data to build predictive, multi- scale biophysical models of tumor growth to optimize therapy on a patient basis, and to provide leadership in these areas to the community. The first clinical trial is a community partnership model and includes The University of Texas at Austin, Seton Hospital, Austin Neurological Associates, and Texas Oncology. Dr. Yankeelov confirmed that this clinical trial includes all breast cancers. He is planning on conducting