Supplementary material BMJ Open Concept ID Name Class 1319998 Acebutolol Adrenergics 1154343 Albuterol Adrenergics 930021 alfuzosin Adrenergics 919986 apraclonidine Adrenergics 1111220 arformoterol Adrenergics 1314002 Atenolol Adrenergics 19034275 bambuterol Adrenergics 1322081 Betaxolol Adrenergics 1338005 Bisoprolol Adrenergics 915542 brimonidine Adrenergics 21603320 carbuterol Adrenergics 950370 Carteolol Adrenergics 1346823 carvedilol Adrenergics 19097824 Clenbuterol Adrenergics 1398937 Clonidine Adrenergics 19086622 dapiprazole Adrenergics 19061088 Dexmedetomidine Adrenergics 990009 Dipivefrin Adrenergics 1337720 Dobutamine Adrenergics 1363053 Doxazosin Adrenergics 1143374 Ephedrine Adrenergics 1343916 Epinephrine Adrenergics 19063575 esmolol Adrenergics 19053979 Fenoterol Adrenergics 1196677 formoterol Adrenergics 1366237 Guanabenz Adrenergics 1344965 Guanfacine Adrenergics 19068969 Hexoprenaline Adrenergics 1181809 Isoetharine Adrenergics 21603309 isoprenaline, combinations Adrenergics 1183554 Isoproterenol Adrenergics 1386957 Labetalol Adrenergics 1192218 Levalbuterol Adrenergics 932815 Levobunolol Adrenergics 1123995 metaproterenol Adrenergics 19009365 methoxyphenamine Adrenergics 1305447 Methyldopa Adrenergics 905531 Metipranolol Adrenergics 1307046 Metoprolol Adrenergics 1308368 Midodrine Adrenergics 42873636 mirabegron Adrenergics 1313200 Nadolol Adrenergics 21603310 orciprenaline, combinations Adrenergics 19026274 p-Hydroxyamphetamine Adrenergics 1327978 Penbutolol Adrenergics Brauer R, et al. BMJ Open 2020; 10:e032426. doi: 10.1136/bmjopen-2019-032426 Supplementary material BMJ Open 1335301 Phenoxybenzamine Adrenergics 1335539 Phentolamine Adrenergics 1135766 Phenylephrine Adrenergics 1345858 Pindolol Adrenergics 1125449 pirbuterol Adrenergics 1350489 Prazosin Adrenergics 19028950 Procaterol Adrenergics 1353766 Propranolol Adrenergics 1154332 Pseudoephedrine Adrenergics 19035396 reproterol Adrenergics 1137529 salmeterol Adrenergics 19012925 silodosin Adrenergics 924566 tamsulosin Adrenergics 1341238 Terazosin Adrenergics 1236744 Terbutaline Adrenergics 21603325 terbutaline, combinations Adrenergics 902427 Timolol Adrenergics 778474 tizanidine Adrenergics 21603319 tretoquinol Adrenergics 19043191 tulobuterol Adrenergics 43532539 vilanterol Adrenergics 19029393 aceclofenac Analgesics (inc. NSAIDs) 19029398 acemetacin Analgesics (inc. NSAIDs) 1125315 Acetaminophen Analgesics (inc. NSAIDs) 21603946 alclofenac Analgesics (inc. NSAIDs) 19059528 Alfentanil Analgesics (inc. NSAIDs) 19018431 alminoprofen Analgesics (inc. NSAIDs) 1103552 almotriptan Analgesics (inc. NSAIDs) 19018432 aloxiprin Analgesics (inc. NSAIDs) aminophenazone, combinations excl. 21604337 psycholeptics Analgesics (inc. NSAIDs) aminophenazone, combinations with 21604341 psycholeptics Analgesics (inc. NSAIDs) 19125628 Aminopyrine Analgesics (inc. NSAIDs) 1036059 Antipyrine Analgesics (inc. NSAIDs) 19136654 Apazone Analgesics (inc. NSAIDs) 1112807 Aspirin Analgesics (inc. NSAIDs) 40254364 avocado and soyabean oil, unsaponifiables Analgesics (inc. NSAIDs) 19016435 benorilate Analgesics (inc. NSAIDs) 21603972 benoxaprofen Analgesics (inc. NSAIDs) 19019620 Benzydamine Analgesics (inc. NSAIDs) 21604279 bezitramide Analgesics (inc. NSAIDs) 1139179 bromfenac Analgesics (inc. NSAIDs) 21604346 bucetin Analgesics (inc. NSAIDs) 21604350 bucetin, combinations excl. psycholeptics Analgesics (inc. NSAIDs) 21604353 bucetin, combinations with psycholeptics Analgesics (inc. NSAIDs) 19032724 Bufexamac Analgesics (inc. NSAIDs) Brauer R, et al. BMJ Open 2020; 10:e032426. doi: 10.1136/bmjopen-2019-032426 Supplementary material BMJ Open 19039703 bumadizone Analgesics (inc. NSAIDs) 1133201 Buprenorphine Analgesics (inc. NSAIDs) 1133732 Butorphanol Analgesics (inc. NSAIDs) 21604363 cannabinoids Analgesics (inc. NSAIDs) 21604318 carbasalate calcium Analgesics (inc. NSAIDs) carbasalate calcium combinations excl. 21604324 psycholeptics Analgesics (inc. NSAIDs) 1118084 celecoxib Analgesics (inc. NSAIDs) 1395573 Chondroitin Sulfates Analgesics (inc. NSAIDs) 19018512 clofezone Analgesics (inc. NSAIDs) 1201620 Codeine Analgesics (inc. NSAIDs) 21604268 codeine, combinations with psycholeptics Analgesics (inc. NSAIDs) 21603980 dexibuprofen Analgesics (inc. NSAIDs) 19056874 Dexketoprofen Analgesics (inc. NSAIDs) 19021940 Dextromoramide Analgesics (inc. NSAIDs) dextropropoxyphene, combinations with 21604282 psycholeptics Analgesics (inc. NSAIDs) 19088393 dezocine Analgesics (inc. NSAIDs) 19088915 diacetylrhein Analgesics (inc. NSAIDs) 21604262 DIAMORPHINE Analgesics (inc. NSAIDs) 1124300 Diclofenac Analgesics (inc. NSAIDs) 21603952 difenpiramide Analgesics (inc. NSAIDs) 1126128 Diflunisal Analgesics (inc. NSAIDs) 1189596 dihydrocodeine Analgesics (inc. NSAIDs) 1126557 Dihydroergotamine Analgesics (inc. NSAIDs) 21604370 dihydroergotamine, combinations Analgesics (inc. NSAIDs) 21604313 dipyrocetyl Analgesics (inc. NSAIDs) 21604323 dipyrocetyl, combinations excl. psycholeptics Analgesics (inc. NSAIDs) 21604328 dipyrocetyl, combinations with psycholeptics Analgesics (inc. NSAIDs) 19056645 droxicam Analgesics (inc. NSAIDs) 1189697 eletriptan Analgesics (inc. NSAIDs) 1145379 Ergotamine Analgesics (inc. NSAIDs) 21604372 ergotamine, combinations with psycholeptics Analgesics (inc. NSAIDs) 19059506 ethenzamide Analgesics (inc. NSAIDs) 21604322 ethenzamide, combinations excl. psycholeptics Analgesics (inc. NSAIDs) 21604327 ethenzamide, combinations with psycholeptics Analgesics (inc. NSAIDs) 1195492 Etodolac Analgesics (inc. NSAIDs) 19011355 etoricoxib Analgesics (inc. NSAIDs) 19095703 fenbufen Analgesics (inc. NSAIDs) 1153928 Fenoprofen Analgesics (inc. NSAIDs) 1154029 Fentanyl Analgesics (inc. NSAIDs) 21603950 fentiazac Analgesics (inc. NSAIDs) 19135796 Feprazone Analgesics (inc. NSAIDs) 21604014 feprazone, combinations Analgesics (inc. NSAIDs) 19054931 floctafenine Analgesics (inc. NSAIDs) 19110711 Flufenamic Acid Analgesics (inc. NSAIDs) 21604374 flumedroxone Analgesics (inc. NSAIDs) Brauer R, et al. BMJ Open 2020; 10:e032426. doi: 10.1136/bmjopen-2019-032426 Supplementary material BMJ Open 21603981 flunoxaprofen Analgesics (inc. NSAIDs) 19064698 flupirtine Analgesics (inc. NSAIDs) 1156378 Flurbiprofen Analgesics (inc. NSAIDs) 19113015 fonazine Analgesics (inc. NSAIDs) 1189458 frovatriptan Analgesics (inc. NSAIDs) 21604356 glafenine Analgesics (inc. NSAIDs) 1360332 Glucosamine Analgesics (inc. NSAIDs) 21604004 glucosaminoglycan polysulfate Analgesics (inc. NSAIDs) 21604317 guacetisal Analgesics (inc. NSAIDs) 1174888 Hydrocodone Analgesics (inc. NSAIDs) 1126658 Hydromorphone Analgesics (inc. NSAIDs) 21604295 hydromorphone and antispasmodics Analgesics (inc. NSAIDs) 1177480 Ibuprofen Analgesics (inc. NSAIDs) 21603979 ibuproxam Analgesics (inc. NSAIDs) 19069104 imidazole-2-hydroxybenzoate Analgesics (inc. NSAIDs) 21603958 indometacin, combinations Analgesics (inc. NSAIDs) 1178663 Indomethacin Analgesics (inc. NSAIDs) 21603976 indoprofen Analgesics (inc. NSAIDs) 19113032 iprazochrome Analgesics (inc. NSAIDs) 19069191 kebuzone Analgesics (inc. NSAIDs) 21604270 ketobemidone Analgesics (inc. NSAIDs) 21604293 ketobemidone and antispasmodics Analgesics (inc. NSAIDs) 1185922 Ketoprofen Analgesics (inc. NSAIDs) 21603985 ketoprofen, combinations Analgesics (inc. NSAIDs) 1136980 Ketorolac Analgesics (inc. NSAIDs) 1189766 Levorphanol Analgesics (inc. NSAIDs) 19071933 lonazolac Analgesics (inc. NSAIDs) 19049709 lornoxicam Analgesics (inc. NSAIDs) 19071936 loxoprofen Analgesics (inc. NSAIDs) 21603997 lumiracoxib Analgesics (inc. NSAIDs) 19125097 Meclofenamic Acid Analgesics (inc. NSAIDs) 19125195 Mefenamic Acid Analgesics (inc. NSAIDs) 1150345 meloxicam Analgesics (inc. NSAIDs) 40254075 meloxicam, combinations Analgesics (inc. NSAIDs) 1102527 Meperidine Analgesics (inc. NSAIDs) 19003010 Meptazinol Analgesics (inc. NSAIDs) metamizole sodium, combinations excl. 21604336 psycholeptics Analgesics (inc. NSAIDs) metamizole sodium, combinations with 21604340 psycholeptics Analgesics (inc. NSAIDs) 1103640 Methadone Analgesics (inc. NSAIDs) 21604280 methadone, combinations excl. psycholeptics Analgesics (inc. NSAIDs) 19005257 Methoxyflurane Analgesics (inc. NSAIDs) 1106740 Methysergide Analgesics (inc. NSAIDs) 19072129 mofebutazone Analgesics (inc. NSAIDs) 19072152 morniflumate Analgesics (inc. NSAIDs) 1110410 Morphine Analgesics (inc. NSAIDs) Brauer R, et al. BMJ Open 2020; 10:e032426. doi: 10.1136/bmjopen-2019-032426 Supplementary material BMJ Open 21604292 morphine and antispasmodics Analgesics (inc. NSAIDs) 19056115 MORPHOLINE SALICYLATE Analgesics (inc. NSAIDs) 1113648 nabumetone Analgesics (inc. NSAIDs) 1114122 Nalbuphine Analgesics (inc. NSAIDs) 40254094 naproxcinod Analgesics (inc. NSAIDs) 1115008 Naproxen Analgesics (inc. NSAIDs) 40254098 naproxen and misoprostol Analgesics (inc. NSAIDs) 1118117 naratriptan Analgesics (inc. NSAIDs) 19015602 Nefopam Analgesics (inc. NSAIDs) 909795 nepafenac Analgesics (inc. NSAIDs) 21604259 nicomorphine Analgesics (inc. NSAIDs) 21604334 nifenazone Analgesics (inc. NSAIDs) 19019023 Niflumic Acid Analgesics (inc. NSAIDs) 19069425 nimesulide Analgesics (inc. NSAIDs) 923829 Opium Analgesics (inc. NSAIDs) 19082874 orgotein Analgesics (inc. NSAIDs) 19003691 oxaceprol Analgesics (inc. NSAIDs) 21603953 oxametacin Analgesics (inc. NSAIDs) 1118045 oxaprozin Analgesics (inc. NSAIDs) 19082880 oxetorone Analgesics (inc. NSAIDs) 1124957 Oxycodone Analgesics (inc. NSAIDs) 1125765 Oxymorphone Analgesics (inc. NSAIDs) 19025925 Oxyphenbutazone Analgesics (inc. NSAIDs) 19129648 Papaveretum