Allergy Across the Life Course - From Origins Towards Prevention 32nd Symposium of the Collegium Internationale Allergologium 30 SEPT - 5 OCT 2018 Mallorca SPAIN Final PROGRAM TABLE OF CONTENTS Welcome Letter........................................................................................... 1 General Information........................................................................................ 2 Social Events ............................................................................................ 2 Optional Excursions ........................................................................................ 3 Program-at-a-Glance........................................................................................ 4 Alain L. de Weck Travel Grant Recipients .......................................................................... 6 Schedule of Events ........................................................................................ 7 Abstracts .............................................................................................. 17 Speaker and Chair Index.................................................................................... 75 Supporters ....................................................................................... Back Cover 30 SEPTEMBER - 5 OCTOBER 2018 Mallorca SPAIN 32nd Symposium of the Collegium Internationale Allergologicum 2016-2018 Dear Friends, COLLEGIUM COUNCIL On behalf of the Council, Marianna Castells and I welcome you to the 32nd Symposium of the Collegium Internationale PRESIDENT Allergologicum, entitled Allergy Across the Life Course - From Origins Towards Prevention, will be held in Palma, Mallorca on the 30 Stephen T. Holgate September - 5 October 2018. PAST PRESIDENT From its inception in 1954, the Collegium has been a very special international group of friends pursuing research excellence across Stephen J. Galli the full spectrum of allergic diseases and allied disorders, in a spirit of open intellectual exchange and debate at meetings held in VICE PRESIDENT/ interesting and stimulating locations across the Globe. We will be revisiting this vision, this time in the charming city of Palma, capital PAST SECRETARY of Mallorca (Majorca). As its name implies, Majorca is the largest island in the Spanish Balearic Islands archipelago in the beautiful GENERAL Mediterranean. Bruce S. Bochner Through oral and poster presentations, this Symposium will highlight the significant scientific progress being made by our discipline SECRETARY GENERAL worldwide, including some of the latest advances in allergy, asthma and immunology. With the genetic and environmental factors Thomas Bieber initiating allergy and the immunological and other factors driving the evolution of its different organ manifestations becoming ever clearer, there has never been a better opportunity to bring together researchers in these fields to explore mechanisms, prevention and COUNCIL MEMBERS novel therapeutic approaches. Eugene Bleecker Barbara Bohle Palma, Mallorca stands out as a jewel in the Mediterranean Sea with its rich and unique Spanish culture and cuisine, including the Mariana Castells famous paella. While we are on the island we will be visiting different parts to sample these as well as our traditional boat trip. We Peter S. Creticos have chosen the end of September for the 2018 meeting because of the lovely climate at this time of the year. Francesca Levi-Schaffer Gunnar Nilsson From the Council and the local organizers we thank you for attending the 32nd Symposium, and look forward to seeing you over the Ruby Pawankar next week in Palma de Mallorca! Massimo Triggiani Kindest Regards, SYMPOSIUM ORGANIZER Mariana Castells Stephen T. Holgate, MD, Mariana Castells, MD DSc FMedSci Organizer, 32nd Symposium President 555 E. Wells St., Suite 1100 Milwaukee, WI 53202 USA www.ciaweb.org 30 SEPTEMBER - 5 OCTOBER 2018 Mallorca SPAIN 1 GENERAL INFORMATION The 32nd Symposium of the Collegium will be held in Palma, Mallorca, Spain. Founded in 124 BC, Palma is a resort city and capital of the Spanish island of Mallorca (Majorca), in the western Mediterranean. The massive Santa María Cathedral, a Gothic landmark begun in the 13th century, overlooks the Bay of Palma. The adjacent Almudaina is a Moorish-style Arab fortress converted to a royal residence. West of the city, hilltop Bellver Castle is a medieval fortress with a distinctive circular shape. Currency The currency used in Spain is the Euro (EUR). There are ATMs widely available for cash withdrawal. Credit cards are also accepted at most hotels, restaurants and shops. The standard electrical voltage in Spain is 220 Volts and 50 Hertz. Language The official language of the 32nd Symposium is English. Social Events Time Zone All Social Events are included in the registration fee for both delegates and accompanying Palma, Mallorca is in the Western European Time Zone (UTC), which is one hour ahead of persons. the Coordinated Universal Time (UTC). Registration Desk Hours Tipping Sunday 30 September 16:00 - 20:00 Restaurants in Palma generally do not expect a tip on orders. If you feel that the service Monday 1 October 7:00 - 13:30, 16:00 - 19:00 warranted an extra amount you are free to but the general assumption is that tipping is Tuesday 2 October 7:30 - 13:00 not a requirement. Wednesday 3 October 7:30 - 13:00, 17:00 - 19:00 Thursday 4 October 7:30 - 13:30, 17:00 - 19:00 Travel Arrangements and Airport Transfers Friday 5 October 7:30 - 13:00 The Palma International Airport (PMI) is the closest airport to the hotel options. Welcome Reception CIA will not provide airport transportation from the Mallorca Airport to the hotels but there Sunday, 30 September 2018, 18:30 – 21:30 are local options that will be available for you to choose from. The Welcome Reception will be held at the Melia Palma Marina with refreshments and an assortment of hors d’oeuvres. To find more details on the transportation options please see the Mallorca Airport website, http://www.palma-airport.info/transportation.html. Informal Dinner Monday, 1 October 2018, 20:00 – 23:00 Venue The Informal Dinner will take place at the Finca Son Termes restaurant. The 32nd Symposium of the Collegium will be held at the Melia Palma Marina Hotel. Boat Ride Weather Tuesday, 2 October 2018, 13:30 – 19:00 The average temperature in October is between 75°F/24°C and 62°F/17°C. Following in the tradition of past Collegium meetings, a boat ride will take place on the third day of the meeting. The group will depart from the Gran Melia Hotel and Melia Palma Marina Hotel at 13:30 to depart on the boat at 13:45 Gala Dinner Thursday, 4 October 2018, 20:00 - 23:00 An elegant dinner will be held on the last evening of the Symposium at Moli de‘s Comte restaurant. 2 32nd Symposium of the Collegium Internationale Allergologicum 2018 TOUR CHOICES Cathedral Walking Miró Museum Tour Wednesday, 3 October, 9:00 – 13:00 Monday, 1 October, 9:00 – 13:00 Half Day Morning (4 hours) Half Day Morning (4 hours) Visit the Fundació Pilar i Joan Miró a Walking tour in the old town of Palma Mallorca, an exclusive museum dedicated to including Cathedral visit the work of artist Joan Miró. Miró had strong ties to Mallorca as his mother and wife were Price: €45.00 born there. The main building of the museum exhibits the work donated by the artist. In Excursion to La Granja addition guests can have a look at the library, a sculpture garden, the studio Sert as well as the Finca Son Boter which Miró used as atelier. Monday, 1 October, 9:00 – 13:00 Half Day Morning (4 hours) Price: €50.00 Visit the beautiful Majorcan country estate Valdermossa “La Granja” near by Esporales. The 17th Wednesday, 3 October, 9:00 – 18:00 century mansion is surrounded by lush Full Day (9 hours) vegetation, magnificent gardens and natural springs. Visitors will have an insight into Valldemossa is a very small town in the the crafts and life of past centuries on a typical Majorcan farm. Some of these handicrafts mountains of Mallorca. It is known for being are still in operation today! The group will get the possibility to taste typical liqueurs and the birth place of the only Majorcan saint, pastries from the region. Santa Catalina Tomàs. The kings of Mallorca valued the pleasant climate so much that they built their summer domiciles in this village Price: €50.00 and the Carthusian monks from Tarragona built their monastry here. The town Palma Bike Tour became famous, however only after the visit of Frédéric Chopin and George Sand who spent their winter 1838/1839 in the monastry. Visit the original Monastry Valldemossa Tuesday, 2 October, 9:00 – 11:30 including the Chopin cell and the Palace King Sancho. Quarter Day Morning (2.5 hours) Price: €75.00 Get to see beautiful Palma from a different angle – bike tour Excursion to Sóller and Price: €35.00 Sa Calobra Thursday, 4 October, 9:00 – 18:00 Cuevas del Drach in Full Day (9 hours) Porto Cristo Sóller is a small village in the heart of the Tuesday, 2 October, 8:30 – 12:30 Tramuntana Mountains which in 2011 Half Day Morning (4 hours) received the UNESCO world heritage status. The high mountain ranges separated the The Cuevas del Drach are impressive valley over centuries from the rest of the island, helping in that way to unfold its dripstone caves located on the east coast of unique charm. The group will take the traditional and most nostalgic railway of the island the island south of Porto Cristo. Mallorcans “Tren de Sóller” from Palma to Sóller city. After a stroll in the city, the group can take