
INTRODUCTION TO CopyrightedPROTEINS STRUCTURE, FUNCTION, AND MOTION SECOND EDITION Materials - Taylor and Francis CHAPMAN & HALL/CRC Mathematical and Computational Biology Series Aims and scope: This series aims to capture new developments and summarize what is known over the entire spectrum of mathematical and computational biology and medicine. It seeks to encourage the integration of mathematical, statistical, and computational methods into biology by publishing a broad range of textbooks, reference works, and handbooks. The titles included in the series are meant to appeal to students, researchers, and professionals in the mathematical, statistical and computational sciences, fundamental biology and bioengineering, as well as interdisciplinary researchers involved in the field.Copyrighted The inclusion of concrete examples and applications, and programming techniques and examples, is highly encouraged. Series Editors N. F. Britton Department of Mathematical Sciences University of Bath Materials Xihong Lin Department of Biostatistics Harvard University Nicola Mulder University of Cape Town - South Africa Taylor Maria Victoria Schneider European Bioinformatics Institute and Mona Singh Department of Computer Science Princeton University Francis Proposals for the series should be submitted to one of the series editors above or directly to: CRC Press, Taylor & Francis Group 3 Park Square, Milton Park Abingdon, Oxfordshire OX14 4RN UK Published Titles An Introduction to Systems Biology: Bayesian Phylogenetics: Methods, Design Principles of Biological Circuits Algorithms, and Applications Uri Alon Ming-Hui Chen, Lynn Kuo, and Paul O. Lewis Glycome Informatics: Methods and Statistical Methods for QTL Mapping Applications Zehua Chen Kiyoko F. 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Wilkinson Golan Yona Big Data in Omics and Imaging: Big Data in Omics and Imaging: Association Analysis Integrated Analysis and Causal Momiao Xiong Inference BigCopyrighted Data Analysis for Bioinformatics and Momiao Xiong Biomedical Discoveries Shui Qing Ye Materials - Taylor and Francis Copyrighted Materials - Taylor and Francis INTRODUCTION TO CopyrightedPROTEINS STRUCTURE, FUNCTION, AND MOTION SECONDMaterials EDITION - Taylor and AMIT KESSEL • NIR BEN-TALFrancis Copyrighted Materials CRC Press Taylor & Francis Group 6000 Broken Sound Parkway NW, Suite 300 Boca Raton, FL 33487-2742 - Taylor © 2018 by Taylor & Francis Group, LLC CRC Press is an imprint of Taylor & Francis Group, an Informa business No claim to original U.S. Government works Printed on acid-free paper and Version Date: 20180208 International Standard Book Number-13: 978-1-4987-4717-2 (Hardback) This book contains information obtained from authentic and highly regarded sources. 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Visit the Taylor & Francis Web site at http://www.taylorandfrancis.com and the CRC Press Web site at http://www.crcpress.com Contents List of Figures xxi List of Tables xxxi List of BoxesCopyrighted xxxiii Preface xxxv Changes in Second Edition xli Acknowledgments xliii Authors xlv Physical Quantities and Constants xlvii List of Acronyms Materials xlix Chapter 1 ■ Introduction 1 1.1 IMPORTANCE OF PROTEINS IN LIVING ORGANISMS 1 1.1.1 Life, proteins and mysterious forces - 1 1.1.2 Molecular organization of living organismsTaylor 2 1.1.3 Proteins have numerous biological roles 6 1.1.3.1 Catalysis of metabolic processes 6 1.1.3.2 Energy transfer and 8 1.1.3.3 Gene expression 11 1.1.3.4 Transport of solutes across biological membranes Francis13 1.1.3.5 Cellular communication 13 1.1.3.6 Molecular recognition 16 1.1.3.7 Defense 17 1.1.3.8 Forming intracellular and extracellular
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